Basic Information

Insect: Drosophila innubila
Gene Symbol: -
Assembly: GCA_004354385.1
Location: NW:3534116-3536562[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0029 0.16 12.1 6.4 2 23 223 244 222 244 0.97

2 11 0.00026 0.015 15.3 3.9 1 23 250 275 250 275 0.95

3 11 0.00058 0.033 14.3 0.6 1 23 282 307 282 307 0.95

4 11 0.00015 0.0082 16.1 1.8 1 23 315 337 315 337 0.95

5 11 0.00015 0.0087 16.1 0.4 3 23 346 366 344 366 0.98

6 11 0.00012 0.0069 16.4 0.1 1 23 372 394 372 394 0.98

7 11 1.6e-05 0.00089 19.2 0.7 1 23 400 423 400 423 0.98

8 11 0.0087 0.49 10.5 5.9 1 23 429 451 429 451 0.96

9 11 2.6e-05 0.0015 18.5 0.8 1 23 457 479 457 479 0.99

10 11 4.6e-06 0.00026 20.9 0.2 3 23 553 574 552 574 0.97

11 11 0.0082 0.46 10.6 5.4 1 23 580 602 580 602 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0029	0.16	12.1	6.4	2	23	223	244	222	244	0.97
2	11	0.00026	0.015	15.3	3.9	1	23	250	275	250	275	0.95
3	11	0.00058	0.033	14.3	0.6	1	23	282	307	282	307	0.95
4	11	0.00015	0.0082	16.1	1.8	1	23	315	337	315	337	0.95
5	11	0.00015	0.0087	16.1	0.4	3	23	346	366	344	366	0.98
6	11	0.00012	0.0069	16.4	0.1	1	23	372	394	372	394	0.98
7	11	1.6e-05	0.00089	19.2	0.7	1	23	400	423	400	423	0.98
8	11	0.0087	0.49	10.5	5.9	1	23	429	451	429	451	0.96
9	11	2.6e-05	0.0015	18.5	0.8	1	23	457	479	457	479	0.99
10	11	4.6e-06	0.00026	20.9	0.2	3	23	553	574	552	574	0.97
11	11	0.0082	0.46	10.6	5.4	1	23	580	602	580	602	0.96

Sequence Information

Coding Sequence: ATGAATGAGGAGACTCCAGCcttaatttatacaatatgCCGCACTTGTTTGTCCAACTTGCTAGAAGATGAAGCCTtcgatttgtttgttgttccgGACCTGGCCAAgaagttgtgtgtgtgtacttcgCTGTCGGTGGAGCACCTGGATGGATTCCCGAGGAACCTCTGCACCACCTGTCACAGCCGTCTAAACGATTTGCATGACTTTCGGAAGCAATGTGTGGAATCTGTGCAGAGATTCAAGGAGTTGATGTCCAGAAACACCTTCATAATCCAAACTATGCCGGACGACGATCATCCTGTTGTGAATGCAGCGCTGCAGGATGATGTTGATGAAGAGGAGCACATTAAATTTGACCCTCTGTTGACTTCAAAAATAGAAATCGACAACGAggataatgtttttaaaatgattaaagaTGTTGACAAAGAATCCGATGATGTAGATAATCTGGAGGATGCATTTGATGACAGCGGAAGCGACTATATCAATGAGGACATGGATTTTCAAGTAGATAGTAGCGATTCCGATGATAAGATGCCGTTGACACGTCTGCGAAGTAGTTCAAGAGCCACAAAGTCCAAGAAAATAACGGATAAGCCCAAAGAGAAGGCAAAACGTAAGCGTGTTCCAACTGCTGAGAGACAATTGAATCGCCCCATTGAATGTCACATTTGTAATCAGAAGTTTATTAAGTCATCATGTTACGAGGAGCATATGAAACACCACAATGATCAATTACCATTTCAGTGTTCAGTGGAGAAGTGTAAAAAGGGATTCACGACTTCCACAGGACTAAACCATCATATGGAGCATACGCACCCGGAATTATGCGAACTTCATCCCTGTACAGTCGAAGGATGCAGTGAATCCTTTGCCCAAACTCGAATGCTGACTCAACATCTGCGAAAAGTACATAATATTGCGAAGCCCATAATACATCCATGTCCGGAATGCGATAAAGTATTCCGTTGTCCAATGGCTCTGAAGAAGCACATGTATGATCACACTGGAGAGGAGCTGCCCTTCGGCTGTAACATCTGCCAGAAACGCTATCGAGTGCCCACGGAACTTCGGGATCATCTTTTGCGCCACGCCGGGATCAGAAACTTTGTTTGTCCTCTTTGCGGTGTGGGCAGGACCACAAAACAGGAGTTGGACAAGCACATGCTGACTCACACAAAGGAAAAGAAGTTCAAGTGTGATCGATGCGATCAAACCTTCAAAGACAAGCCATCTGTGTCCAGGCACATCAAGGTGGTGCACTTGCAAATTAGGAACTTTGTCTGCCAGTATTGCCAAAAGTCCTTCGCCAGCGCTTATCACTGCAAGACTCACGAGAAATTACACACTAGAAACGATTGTTTTGAATGTAAGATCTGTGGAAGCAGTTTCCCTTTTGGGAGTAGATTAACAAAGCACTTAAGGACTCATGAGAAAGGCAAGAAGACGAAAACTGATGGGGATGTTCAGAAGGAGGTGAAAGAACCAGTTGTaataaagaaaccaaaaattCCTGCCAAACCAAGAGATCTACGTCGTGTGGAGGTAGTTAATATATCTCAATTAGCTGGCACTGCTGTTAATCCGTTTCCATCGGTACTAGTATCATCCCCGCAAGATAATTTAACCAAAAGCGAAGGAAAACCCATTTGTCTGGACtgtgacaaaaattttaccaCAATTGGTAATTTGAGGATCCACATCAAGACGGTACACGATAAGATCAAGGACTTTGCCTGCCGCTTCTGTCCCAATCGGTTTAGCAAAAAGTGTAATCTCCGTCGTCATGAGTATACGCATACGGGGGAAAAGCCGTACGAGTGTAAAAAAAGAGCCgaggaaaagaaagaaagctaA
Protein Sequence: MNEETPALIYTICRTCLSNLLEDEAFDLFVVPDLAKKLCVCTSLSVEHLDGFPRNLCTTCHSRLNDLHDFRKQCVESVQRFKELMSRNTFIIQTMPDDDHPVVNAALQDDVDEEEHIKFDPLLTSKIEIDNEDNVFKMIKDVDKESDDVDNLEDAFDDSGSDYINEDMDFQVDSSDSDDKMPLTRLRSSSRATKSKKITDKPKEKAKRKRVPTAERQLNRPIECHICNQKFIKSSCYEEHMKHHNDQLPFQCSVEKCKKGFTTSTGLNHHMEHTHPELCELHPCTVEGCSESFAQTRMLTQHLRKVHNIAKPIIHPCPECDKVFRCPMALKKHMYDHTGEELPFGCNICQKRYRVPTELRDHLLRHAGIRNFVCPLCGVGRTTKQELDKHMLTHTKEKKFKCDRCDQTFKDKPSVSRHIKVVHLQIRNFVCQYCQKSFASAYHCKTHEKLHTRNDCFECKICGSSFPFGSRLTKHLRTHEKGKKTKTDGDVQKEVKEPVVIKKPKIPAKPRDLRRVEVVNISQLAGTAVNPFPSVLVSSPQDNLTKSEGKPICLDCDKNFTTIGNLRIHIKTVHDKIKDFACRFCPNRFSKKCNLRRHEYTHTGEKPYECKKRAEEKKES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00507044; iTF_00575761;
90% Identity: iTF_00507044;
80% Identity: -