Basic Information

Insect: Drosophila falleni
Gene Symbol: Zbtb41
Assembly: GCA_035045575.1
Location: JAWNOV010000167.1:3143337-3145523[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0078 0.59 10.9 5.9 2 23 223 244 222 244 0.97

2 12 0.00036 0.027 15.1 4.7 1 23 250 275 250 275 0.95

3 12 0.0017 0.13 13.0 0.4 1 23 282 307 282 307 0.95

4 12 0.0002 0.015 15.9 1.8 1 23 315 337 315 337 0.95

5 12 0.00028 0.021 15.4 0.8 3 23 346 366 344 366 0.98

6 12 5.5e-05 0.0041 17.6 0.6 1 23 372 394 372 394 0.98

7 12 3.1e-05 0.0023 18.4 0.6 1 23 400 423 400 423 0.97

8 12 0.012 0.89 10.3 5.9 1 23 429 451 429 451 0.96

9 12 3.6e-05 0.0027 18.2 0.8 1 23 457 479 457 479 0.99

10 12 0.00019 0.015 15.9 0.3 3 23 553 574 552 574 0.97

11 12 0.011 0.83 10.4 5.4 1 23 580 602 580 602 0.96

12 12 0.00016 0.012 16.2 5.1 1 23 608 630 608 630 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0078	0.59	10.9	5.9	2	23	223	244	222	244	0.97
2	12	0.00036	0.027	15.1	4.7	1	23	250	275	250	275	0.95
3	12	0.0017	0.13	13.0	0.4	1	23	282	307	282	307	0.95
4	12	0.0002	0.015	15.9	1.8	1	23	315	337	315	337	0.95
5	12	0.00028	0.021	15.4	0.8	3	23	346	366	344	366	0.98
6	12	5.5e-05	0.0041	17.6	0.6	1	23	372	394	372	394	0.98
7	12	3.1e-05	0.0023	18.4	0.6	1	23	400	423	400	423	0.97
8	12	0.012	0.89	10.3	5.9	1	23	429	451	429	451	0.96
9	12	3.6e-05	0.0027	18.2	0.8	1	23	457	479	457	479	0.99
10	12	0.00019	0.015	15.9	0.3	3	23	553	574	552	574	0.97
11	12	0.011	0.83	10.4	5.4	1	23	580	602	580	602	0.96
12	12	0.00016	0.012	16.2	5.1	1	23	608	630	608	630	0.99

Sequence Information

Coding Sequence: ATGAATGAGGAGACTCTAGCCTCAATACATACAATATGCCGCACTTGTTTGTCCAGCTTGGAGATCGCTGAAGCCTTCGATCTGTTTGTTGTTCCGGGTCTGGCCAagaagttgtgtgtgtgtacttcgCTGTCAGTGGAGCACCAGGATGGATTCCCGAGGAACCTCTGCACCACCTGTCACAGCCGTCTCAACGATTTGCATGACTTCCAGAAGCAATGCGTGGATTCAGTGCAGAGATTCAAGGAGTTGGTGTCCAGAAACTGCTTCGTTATCCGAGCTCTGCCGGACGACGATCATCCTGTCGTGAATGCTGCGCTGCAGGATGATGTCGATGAAGAGGAGCACATTATCTTTGACCCTCTGTTGACTTCTAAAATAGAAATTGACAACGAGGaaagtgtttttaaaatgattgaaGATGTCGACAAAGAATCTGATGATGTTGATAATTCGGAGGATGCATTTGATGACAGCGGAAGCGACTATATCAATGACGACATGGATTCTCAAGTAGATAGCAGCGAGTCCGATGACGAGAGGCCGTTGTCCCGCCTGCGAAATAGTTCCAGAGCTACAAAATCTAAGAAAGAAACGGATAAGCCTACAGAGAAGCCAAAACGTAAGCGTGTTCCAGCTGCTGAGAGGCAATTGAATCGCCCCATAGAATGTCACATTTGCAATCAGAAGTTTATTAAGGAATCTTGCTACGAAGAGCATATGAAACATCACAATGACCAATTACCATTTCAGTGCTCAGTGGAGAAGTGTAAAAAGGGATTCACGACTTCTAAAGGACTAAAGCATCATATGGAACACACTCACACGGAGCTATGCAAACTTCATCCCTGTACGGTCGAAGGATGCAGTGAAGCCTTTGCACAAACTCGAATGCTGACTCAACATCTGAGAAAGGTACATAATGTTGCCAAGCCCATTATACATCCATGTCCAGAATGCGATAAAGTATTCCGTTGTCCAATGGCACTGAAGAAACATATGTATGATCACACTGGAGAGGAGCTGCCCTTCGGCTGTAACATTTGCCAGAAACGCTATCGAGTGAATACCGAACTCCGTGATCATCTTTTGCGCCACGCCGGGATCAGAAACTTTGTTTGTCCTCATTGCGGTGTGGGCAGGACCACAAAACAGGAGTTGGACAAGCACATGCTGACTCACACAAAGGAAAAGAAGTTCAAGTGTGATCAATGCGATCAGACCTTCAAGGACAAGCCATCTGTGTCCAGACACGTCAAGGTGGTGCACATGCAAATTAGGAACTTTGTCTGCCAGTATTGCCAAAAGTCCTTCGCCAGCGCTTATCACTGCAAGACTCACGAGAAATTACACACTAGGAACGATTGTTTCGAATGCAAAATCTGTGGCAGCAGCTTCCCTTTTGGAAGTAGATTAACAAAGCACTTAAGGACCCATGAGAAAGGCAAGAAGACGAAAACTGATGGGGTTGTTCAGAAGGAGTCCAAAGAACCAGATGttaaaaagaaaccaaaaattCCTGCCAAGCCAAGAGATCTACGTCGTGTTAAGGTAGTGAATATATCACAATTAGCTGGCACTGCTGTTAATCCGTTTTCAACGGTACTAGTATCATCCCCGCAAGAAAATTTAACCAAAAGCGAAGCAAGACCCTTTTGTCTGCTCTGTGACAAAAATTTCACCACAATTGGTGGTTTGAGAATCCACATCAAGACGGTACACGATAAGATCAAGGACTTTGCCTGCCGCTTCTGTCCCAATCGTTTTAGCAAAAAATGTAATCTACGTCGTCATGAGTATACACATACAGGGGAAAAGCCGTACGAGTGTAACGTATGCAATCAGCATTTTAGACATGATAAAACCTTAATAAATCATATGAAATCACACAACAGAAAAGAACCgaggaaaagaaagaaagctgagcccaaaacaaaatatcCTTCAAAAGAACCTGAGGTCTCTAGAGTGAGACTAAATACGGAACCAGTAAAAAACTACGAGCAGTTTCAAGATCCAGATGCAGAACGAGCTGCTGCAATGGCTCAATTGATGGCGCAACAATTGGAAGAAAGTGAAGCGAAGCGTAAAGCGGAAGAGAAAACTCGGAAAATTCAGGAGGCAGCGTGCGAGCAGCTCCAGAAATTGCAAAAGCCGCAGATCACCTATGATAGGCTTTCTAAATAA
Protein Sequence: MNEETLASIHTICRTCLSSLEIAEAFDLFVVPGLAKKLCVCTSLSVEHQDGFPRNLCTTCHSRLNDLHDFQKQCVDSVQRFKELVSRNCFVIRALPDDDHPVVNAALQDDVDEEEHIIFDPLLTSKIEIDNEESVFKMIEDVDKESDDVDNSEDAFDDSGSDYINDDMDSQVDSSESDDERPLSRLRNSSRATKSKKETDKPTEKPKRKRVPAAERQLNRPIECHICNQKFIKESCYEEHMKHHNDQLPFQCSVEKCKKGFTTSKGLKHHMEHTHTELCKLHPCTVEGCSEAFAQTRMLTQHLRKVHNVAKPIIHPCPECDKVFRCPMALKKHMYDHTGEELPFGCNICQKRYRVNTELRDHLLRHAGIRNFVCPHCGVGRTTKQELDKHMLTHTKEKKFKCDQCDQTFKDKPSVSRHVKVVHMQIRNFVCQYCQKSFASAYHCKTHEKLHTRNDCFECKICGSSFPFGSRLTKHLRTHEKGKKTKTDGVVQKESKEPDVKKKPKIPAKPRDLRRVKVVNISQLAGTAVNPFSTVLVSSPQENLTKSEARPFCLLCDKNFTTIGGLRIHIKTVHDKIKDFACRFCPNRFSKKCNLRRHEYTHTGEKPYECNVCNQHFRHDKTLINHMKSHNRKEPRKRKKAEPKTKYPSKEPEVSRVRLNTEPVKNYEQFQDPDAERAAAMAQLMAQQLEESEAKRKAEEKTRKIQEAACEQLQKLQKPQITYDRLSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00523112;
90% Identity: iTF_00523112;
80% Identity: -