Dinn002207.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila innubila
Gene Symbol
ftz-f1
Assembly
GCA_004354385.1
Location
NW:21134289-21186517[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 2 1.3e+04 -7.7 17.3 46 113 25 93 8 120 0.62
2 5 0.12 8.1e+02 -1.3 3.9 48 140 131 217 120 271 0.54
3 5 2 1.3e+04 -11.0 14.9 33 156 222 345 197 392 0.44
4 5 2e-19 1.3e-15 57.3 0.4 1 79 565 642 565 704 0.79
5 5 1.2e-71 7.6e-68 229.3 1.1 157 408 790 1034 757 1036 0.90

Sequence Information

Coding Sequence
ATGAATAACTTTAATGTACCTTTGATGGccgagagcagcagcagcaacattgttAGCTATGCAGCtagcaacaatgacaacaacaaccatcaACAGCATcaccatcagcaacagcaaccgcaacaacaacagcacctgCAACACcatcaccaacaacaccaacaacaacaattgctgccACATCATCACAAGGATCAAATGCTTGCTGCTGGCAGCACACCAATGATTCCGTTTATCACCTACACACAACTGCAGAAGGacgcacaacagcagcaacaacagcaacagcagaattCCAATTCGAATCCGCCCGTTGATAGTTTTAGCACACTTCAGGCCATCAATGACAGCCAATTGGATGGTGGCGTCTCCCTAAGTGGACTCTGTGAACGCATCTTCGCCAGTCCAAATCCACATAGCAATAGCAATCACACCcccagcaataataacaacaacaacaacacaaataacaacaacaacaatgtggaTGACAAGTTAACAACGCCATCTAGCGGTGGTGTCATCAATAATGGTGCTGTCATCATTGAATCAGTCACAATGCCATCATTTGCCAACTTATTGttcaacaacaaccgcaacaaccacaacaatcacaacaaccacagcaacaacaacaatcaggcTACAGTCAATGGTGTTGAGTCTTTAAATAGCATTGATCCCGTGTTGTTGCAAAAGTCAAACACTATGGAATATCATCAGCTGAAGCCGTTGGAGAATGTTGCAAGTTctgctgtggcagctgttgtAAGCACCTCAAGTTTCCTTAGCTCAACAACGGCGCAGTTGTTGGACTTTGAGGTGGTTGCCACTAAGGATAcatcagttgttgttgttgctggtaatGGTATTGctgatacaacaacaactgctgctcccgctgctgcagcaacaacaacaaccactgcCAATCGTAGCTCGTTGCACAGCATCGAGGAATTAGCAGCCAGTTCCTGTgccacaaacaaaacaacaagcaacaatacaacaagtacaacacaacaacaacaattgcatcatcagcaacaacaacaacaacaggctgGCAATCTCAGTGGCTCTAATCTCAGCTCAGATGATGAGTCAATGTCGGAGGATGAATTTGGTCTAGAGATTGATGATCATGGGGGCTATCAGGAGACCAACTCATCCCATTCGCAACAAAGTGGCAATGGAGCtgctggcaatggcaatgccaacGCTGGCAACTCTGGCCAACTATTGAATGGCACTGGCGGTGGCAGCTCTGGTGGCAACGGTTACATGTTGCTGCCACcagctggtggtggtggtggtggcaacAACTCTGCCTCTGGCGCCTCACACATGTCCGGCAATATTGGCAGCGGCGGCGGTGCGGGCGGTGGAGCGGGCACAACCGCTGGCAGTGGACATCATGGCGGAACGAGTGCCACATCCGGCGGTGGTGAAGCCATCGATTTCAAGCATCTGTTTGAGGAGCTTTGCCCCGTCTGCGGTGACAAGGTGAGTGGGTATCATTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGATTCTTCAAGCGCACCGTTCAAAACAAAAAGGTCTACACATGCGTTGCGGAGCGTTCCTGCCACATTGATAAGACACAGCGCAAACGCTGTCCATACTGTCGATTCCAAAAGTGCCTCGAGGTGGGCATGAAACTGGAGGctGTTCGAGCGGATCGCATGCGTGGCGGTCGGAACAAGTTCGGACCGATGTACAAAAGGGATCGGGCGCGAAAGCTGCAGGTGATGCGTCAGCGCCAATTGGCGCTTCAGGCGCTGCGCAGTTCGATGGGATCGGACATAAAGCCGACGCCTCTGTCGCCGGGTTATCAGCAAGCATATccaaatatgaatattaagcaagaaatacaaatacctCAGGTATCCTCACTCACACAGTCGCCGGATTCATCGCCTAGTCCCATTGCCATTGCTTTGGGCCAGGTTAATGCGAGCGGGGGCGGTGTGATAGCCACGCCCATGAATGCCGGCAATGTGAGTggcggcaatggcaacggcagcTCCTCATTgggcagtggcaacaacaacaacaacaataccaacaacaacagcagcagcagcacaggCAGCGGTGGCAGTGCAggcggcggaggaggaggaggaggtggtgGCAACAACgctggcggcggcggcggtggcaacAACgctggcggcggcggcggtggcaacaacaacaacagcaacaatggcgATGGCCTGCTACGCAACGGAAAcggcagcaatggcaacagcaacagcagctgccatGAAACCGGAACTGGATCTCTGCAGAACTCAGCCGAATCGAAATTGTGctttgaTTCTGGCACACATCCATCGAGCACAGCCGATGCGCTCATTGAGCCCCTGAGggtatcgcCAATGATACGTGAATTTGTGCAATCGATCGACGATCGGGAATGGCAGACGCAACTGTTTGCGCTGCTGCAGAAGCAGACGTACAATCAGGTGGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTCGATCAGAATCTGTTCTCGCAAGTCGATTGGGCAAGAAACACCGTCTTCTTTAAGGATCTGAAGGTGGACGATCAGATGAAGCTGCTGCAGCATTCGTGGTCCGATATGCTTGTACTTGATCATCTGCATCATCGCATACATAACGGTCTGCCGGATACGACGCAATTGAATAACGGTCAGGTCTTCAATCTAATGAGCCTCGGCCTCTTGGGCGTACCCCAGTTGGGTGATTACTTCAATGAGTTGCAAAATAAACTGCAGGATCTAAAGTTCGATATGGGCGATTATGTGTGCATGAAATTCCTAATACTATTAAATCCAGATGTGCGCGGCATTGTCAACAAGAAGACCGTCTTGGAGGGACACGAGAGTGTGCAGGCAGCGCTGCTGGATTACACGCTTACGTGTTATCCCTCAGTCAATGACAAATTCAGGAGGCTATTAAACATACTACCGGAAATCCACGCCATGGCCGCACGGGGCGAGGAGCATCTCTACTCGAAGCACTGCGCGGGAAGTGCGCCAACGCAGACGCTGCTCATGGAGATGTTGCATGCCAAGAGGAAGGTGTAA
Protein Sequence
MNNFNVPLMAESSSSNIVSYAASNNDNNNHQQHHHQQQQPQQQQHLQHHHQQHQQQQLLPHHHKDQMLAAGSTPMIPFITYTQLQKDAQQQQQQQQQNSNSNPPVDSFSTLQAINDSQLDGGVSLSGLCERIFASPNPHSNSNHTPSNNNNNNNTNNNNNNVDDKLTTPSSGGVINNGAVIIESVTMPSFANLLFNNNRNNHNNHNNHSNNNNQATVNGVESLNSIDPVLLQKSNTMEYHQLKPLENVASSAVAAVVSTSSFLSSTTAQLLDFEVVATKDTSVVVVAGNGIADTTTTAAPAAAATTTTTANRSSLHSIEELAASSCATNKTTSNNTTSTTQQQQLHHQQQQQQQAGNLSGSNLSSDDESMSEDEFGLEIDDHGGYQETNSSHSQQSGNGAAGNGNANAGNSGQLLNGTGGGSSGGNGYMLLPPAGGGGGGNNSASGASHMSGNIGSGGGAGGGAGTTAGSGHHGGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPMNAGNVSGGNGNGSSSLGSGNNNNNNTNNNSSSSTGSGGSAGGGGGGGGGGNNAGGGGGGNNAGGGGGGNNNNSNNGDGLLRNGNGSNGNSNSSCHETGTGSLQNSAESKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDTTQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHESVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00472411;
90% Identity
iTF_00523005;
80% Identity
iTF_00523005;