Basic Information

Insect: Drosophila infuscata
Gene Symbol: L
Assembly: GCA_035042205.1
Location: JAWNLR010000343.1:6406500-6415393[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.1e-05 0.00078 19.9 2.9 1 23 171 193 171 193 0.98

2 17 0.37 27 5.6 6.2 1 23 199 221 199 221 0.97

3 17 1.8e-07 1.3e-05 25.5 3.2 1 23 227 249 227 249 0.99

4 17 1.3e-05 0.00095 19.6 0.4 1 23 255 277 255 277 0.99

5 17 0.13 9.1 7.1 0.1 2 23 351 376 350 376 0.92

6 17 0.00044 0.032 14.8 0.4 2 23 409 431 408 431 0.96

7 17 0.029 2.1 9.1 0.7 1 23 496 518 496 518 0.97

8 17 0.0054 0.39 11.4 0.1 2 23 526 547 525 547 0.91

9 17 0.00022 0.016 15.8 0.1 1 23 555 579 555 579 0.93

10 17 5.4 3.9e+02 1.9 1.6 2 23 615 637 614 637 0.95

11 17 0.0027 0.19 12.3 1.1 1 23 688 711 688 711 0.97

12 17 0.0068 0.49 11.1 1.6 2 23 886 908 885 908 0.96

13 17 0.12 8.7 7.1 0.1 1 23 914 936 914 936 0.92

14 17 0.58 42 5.0 0.4 2 23 944 965 943 965 0.93

15 17 0.68 49 4.8 0.6 2 23 1067 1088 1067 1088 0.94

16 17 0.051 3.7 8.3 0.0 1 23 1098 1120 1098 1120 0.94

17 17 0.00023 0.017 15.7 1.2 1 23 1125 1147 1125 1147 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.1e-05	0.00078	19.9	2.9	1	23	171	193	171	193	0.98
2	17	0.37	27	5.6	6.2	1	23	199	221	199	221	0.97
3	17	1.8e-07	1.3e-05	25.5	3.2	1	23	227	249	227	249	0.99
4	17	1.3e-05	0.00095	19.6	0.4	1	23	255	277	255	277	0.99
5	17	0.13	9.1	7.1	0.1	2	23	351	376	350	376	0.92
6	17	0.00044	0.032	14.8	0.4	2	23	409	431	408	431	0.96
7	17	0.029	2.1	9.1	0.7	1	23	496	518	496	518	0.97
8	17	0.0054	0.39	11.4	0.1	2	23	526	547	525	547	0.91
9	17	0.00022	0.016	15.8	0.1	1	23	555	579	555	579	0.93
10	17	5.4	3.9e+02	1.9	1.6	2	23	615	637	614	637	0.95
11	17	0.0027	0.19	12.3	1.1	1	23	688	711	688	711	0.97
12	17	0.0068	0.49	11.1	1.6	2	23	886	908	885	908	0.96
13	17	0.12	8.7	7.1	0.1	1	23	914	936	914	936	0.92
14	17	0.58	42	5.0	0.4	2	23	944	965	943	965	0.93
15	17	0.68	49	4.8	0.6	2	23	1067	1088	1067	1088	0.94
16	17	0.051	3.7	8.3	0.0	1	23	1098	1120	1098	1120	0.94
17	17	0.00023	0.017	15.7	1.2	1	23	1125	1147	1125	1147	0.97

Sequence Information

Coding Sequence: ATGATGGCCTTAAAGATGTTATATCGTGGTCCCAGTTCGCGTTTGGAGAATTTGATTGAAAAGATTCAGGCCACAAAGGAGATTACAAATAACGaCATGTACAGCACGCACACCTCGTCGAGCTACTCGCCCAGCATCTCGGATGGCACATTGACGCCCAACTCGgtacagcagctgcagcagcagtcgtcCAAGGCTGCCGGCGAGGACACTCACAGCGAAGAGTCCAAGGCAAATGGTGAGGGTCCTGCTGCGGAGCAACAGGATCAGGCCAAGCCGAAGCGACCCGCTCAtttgcatcatcatcatcatcatcattatcatcatcagcaggcGCTGAAAATTGCCAACAAGCTGCGCAAAATCAATAAGGAAGCCAAGTTGGCAAACGCCGGAGCAGGAGCACATGgcacaggagcagcaggagcaggtggtggaggtggtggAGTTGCCGCCAGCAAGTTTGATAAGTTGACAGGCGAGGGAATTAAAAGTCGCGGCGACGGCTCCTATCAGTGTCAGTTCTGTGATAAATCATTTCCGCGACTCGGCTACTTGAAGCATCACGTCCAGaGCCATGCCGAACATTTGCCTTTCAAGTGCGAATACTGCGCCAAGCTGTTCAAGCATAAGCGATCCCGAGATCGCCACAAGAAGCTCCACACAAACGAGAGGAACTACAAGTGTCCGCATTGTGAGGCTGCTTTCTCCAGAAGCGATCATTTAAAGATTCACATGAAGACGCACGATATCCAGAAGCCGTTCCAGTGCAGCATGTGCAATCGTGGCTACAACACTGCCGCCGCTTTGACCTCGCACATGCAGAAGCACAAGAAGAATGCTGCAATTCTGGCAGCTGGTGGCAATCCCAATGCCCTGAATTATAGTCCACGCTCCACGGGATCAGCGTCCATTTCGAGCAATGGCAGTCTGCACAAGCGACGCTATGCTTTGGCGCTCGCCTCGGACAGCAGTCCGAGTCGTCTGGAGTTCCCCAAGCGGGCACGTGGTGCTACCGTgccgaccacgcccactccaacGCCCCTGCTCAGATGCAGCTACTGCAGTCCCAAGGTGACCGAGTTTAGCAGCCTGGAACAGTTGAATGCCCATCTGCAGGCGGCAcacgaacagcaacagcagccgggTGCCAGGAGTTCGACAGCCACCAGCAGAGAGACCACAGTGGAGTCAGTGGAGCCACCCACGAATGGTTTCCAGCTCAGCTGCGAATATTGCACAATGAAATTTGGGAATATTGCGGCACTCTTTCAACACATGCGGACCACCCACTTGGATCGCCTGAGCAGTCCCAATTCGTATTATGAGCACTTTAATCGTTTGGCCACCGCTGGAACGTTTAGTCCACGTTTGGATATGGCCAAGATCAAGCAGGATTTGCCTAGTCCGCCGGCGGAGGAGCTGCCAACGGATCTGAGCAGCAATAAGCGACGAACGTTGACACCGCCAGCGCCACCTGGCGTCTTCTTTTGCAATCAGTGCAACGCAGGGTTGCCAGACTTTGAGAGTTTTCGCAATCATCTCAAGACGCACATTGCGGAGGGCATGCAACTGATATGTCCCCACTGCGGATTGAGTCTGCCGGAGCAGAGTGAATTCGAGCGACACGTGGTCGCCCATTTCCTGATCACCAGTTCCGAGTTCAATTGCGGCGCCAGCTGTGGCAAATCGTTTGCCAAATCGGAGGAGCTGCAACAGCATCTGATCAGCGAACACGTTCAGACGCTGCTCAAGTGTGTGATCTGCTCGGAGCTGTGCGAGAATCGCATGTCGATGCAGCTCCATTTGGCCTGTGCCCACAGCCAGGAGACGAAGCTGCTCCGTTGCAGCGCCTGCTTGGAGCTCTTTCGCAACGATACCGATTTTCATGTGCATGTCAAGACTCGTCATCAACTGGTAGGTGGTGGCAGTGCGTCGGGCGGTGCAGTTGGTGGACCACCCACTGCTCCGCCTGCCAATCCGTTGCAGTGCATGTTTTGTCGCGCCGTTTGCGCCTCGGAGCTGGAAATGCATTTCCATTTGGCAGCGCACGCCCGTCAATTCCGTTGTCCCAGTTGCCCGGAAACGTTCCACGTCGAATTCCTGCTCGATCGGCATATGCAGAGCCAGCATGGCGGTGTCAAGGATGgcaagcaggagcagcagggcGCCAACAATGCGATGGGCAGTCTTTATGTGAACGCCTTGTTGCCACcgttggcggcggcggcagcggctgcggcagctgccacaaataATAACAGTAATCTGCATATTGATTACAATGTGGCATTCAAGGGTCTCTTTGGAGGCggcaatgccacgcccaccaacACACAGCCAGCCAACAAGTTCTACAGTCCTTTGCAGGTGGATACAAGTGCGCTGAAGCCGCAACAAACCCCGCATCCCGCACTGATGTACGGACTCAGTCAGCGCTATTTGATGGAGATGTATGCGGCGAAGGCAACCTCACCGGCGGCCAGTGCACCCGAGCTGCCGGCACAGGCAACCCAAAATGCGGCAAATGCGACGGCATCCAGCACCGGCAGCAGTTACAGTTGTGGCATGTGCGAGCGCCAGGATTTGCGCAGCGAGGCCGAACTCCATTCGCATCGCAAGTTGGCGCATAATCTGAAGACGGGTGTCAGTTTGAGATGTGCCTACTGCTCGGGCAATTACAAGTCGCGGgcggagctggagcagcacaTGAAGAGCTGCCACAATTCGAGTGGCAAGCACAAGTGTCTCATTTGCGACGAGATCTTTCCGTCGCCGGCGATACTCGCCGAGCACAAGTTGCAGCACTCGAAGGTGGGTCAGTCGGGTAAGTGTGCCCATTGtggccagcagctggagcatGTCGCCGCATTCCGTGCCCATCTCGGCGAGCATGGTAACGATGGTAATTTGCCGATGGCCTGCATTTGTTGCCGGCAAACTTTGCACTCGGAATTCGAGTTGAGTTTGCATGCAAAATTCCACACAAAATCACCAAGTTGTGGCAGCCTCCAGGAGCCCGTGTGTGCGCTGTGCCTGGAACCCTTGCCTGGTGCGGGAGAAACCGCCAAGCTGTGTGAGAAATGTTGTCGCAAACATAATCTGAATGGCAAACGCAACAAGGATGCAGCTgttccaccaccaccagcaccacccacagcagcagcagcagccaactcTGTGGCTTATCTCGAGAATCGTTGTAATCTGTGCAAACTGATATTGCCACATGCCAAGAAACTGCAGGAGCATCTTGTGGAGCACACATTCGCGGGCACCGAGCAACGTGGTTTTAATTGCTACATTTGCTCGGCGGTTTTTACGGCACCCGGTGGTCTCCTGGCCCACATTGGGGAGCACGGTGCTCGACCCTACGATTGCAATTTGTGCCCGGAGAAGTTTTACTTCCGCGCCGAGCTCGAGCATCATCAGCGTGCCCATGAGCTGAGGCAAATCCCAGCTATCGCTCCGCCACGGCCCACAACCAAACAGGAGACCCAGCTCAGCTCGTCGGCCAGTTCACCCGTTCTCACGCTCAGTCCCAGTCATGTGAAGCAGGAGCTCTACGAATCGGAGGCGGAGCGAAACTCACCGCAACCCGACGAGGACTCGCCCGCCcccgaggaggaggagtacATTGAGGTCGAGCAGATGCCGCATGAGACTCGCTCCAATGAACTGGTCACCACGGAACGCTCCAGCAACAGCGCCTAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEITNNDMYSTHTSSSYSPSISDGTLTPNSVQQLQQQSSKAAGEDTHSEESKANGEGPAAEQQDQAKPKRPAHLHHHHHHHYHHQQALKIANKLRKINKEAKLANAGAGAHGTGAAGAGGGGGGVAASKFDKLTGEGIKSRGDGSYQCQFCDKSFPRLGYLKHHVQSHAEHLPFKCEYCAKLFKHKRSRDRHKKLHTNERNYKCPHCEAAFSRSDHLKIHMKTHDIQKPFQCSMCNRGYNTAAALTSHMQKHKKNAAILAAGGNPNALNYSPRSTGSASISSNGSLHKRRYALALASDSSPSRLEFPKRARGATVPTTPTPTPLLRCSYCSPKVTEFSSLEQLNAHLQAAHEQQQQPGARSSTATSRETTVESVEPPTNGFQLSCEYCTMKFGNIAALFQHMRTTHLDRLSSPNSYYEHFNRLATAGTFSPRLDMAKIKQDLPSPPAEELPTDLSSNKRRTLTPPAPPGVFFCNQCNAGLPDFESFRNHLKTHIAEGMQLICPHCGLSLPEQSEFERHVVAHFLITSSEFNCGASCGKSFAKSEELQQHLISEHVQTLLKCVICSELCENRMSMQLHLACAHSQETKLLRCSACLELFRNDTDFHVHVKTRHQLVGGGSASGGAVGGPPTAPPANPLQCMFCRAVCASELEMHFHLAAHARQFRCPSCPETFHVEFLLDRHMQSQHGGVKDGKQEQQGANNAMGSLYVNALLPPLAAAAAAAAAATNNNSNLHIDYNVAFKGLFGGGNATPTNTQPANKFYSPLQVDTSALKPQQTPHPALMYGLSQRYLMEMYAAKATSPAASAPELPAQATQNAANATASSTGSSYSCGMCERQDLRSEAELHSHRKLAHNLKTGVSLRCAYCSGNYKSRAELEQHMKSCHNSSGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCAHCGQQLEHVAAFRAHLGEHGNDGNLPMACICCRQTLHSEFELSLHAKFHTKSPSCGSLQEPVCALCLEPLPGAGETAKLCEKCCRKHNLNGKRNKDAAVPPPPAPPTAAAAANSVAYLENRCNLCKLILPHAKKLQEHLVEHTFAGTEQRGFNCYICSAVFTAPGGLLAHIGEHGARPYDCNLCPEKFYFRAELEHHQRAHELRQIPAIAPPRPTTKQETQLSSSASSPVLTLSPSHVKQELYESEAERNSPQPDEDSPAPEEEEYIEVEQMPHETRSNELVTTERSSNSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538445;
90% Identity: iTF_00525350;
80% Identity: -