Basic Information

Insect: Drosophila infuscata
Gene Symbol: ZNF639
Assembly: GCA_035042205.1
Location: JAWNLR010000096.1:1448854-1451977[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.015 1.1 10.0 0.4 3 23 310 331 309 331 0.91

2 10 0.00016 0.012 16.2 0.5 6 23 340 357 340 357 0.99

3 10 9.7e-06 0.0007 20.0 0.3 1 23 363 386 363 386 0.98

4 10 0.00013 0.0096 16.4 0.5 1 23 398 420 398 420 0.98

5 10 0.00032 0.024 15.2 7.7 1 23 427 450 427 450 0.96

6 10 1.4e-05 0.00098 19.6 1.8 1 23 456 478 456 478 0.96

7 10 0.34 25 5.7 0.9 2 23 487 508 486 508 0.96

8 10 0.00013 0.0094 16.5 2.8 2 23 514 536 513 536 0.95

9 10 2.3e-07 1.7e-05 25.1 0.7 2 23 543 564 542 564 0.97

10 10 0.0002 0.015 15.9 4.4 1 23 570 593 570 593 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.015	1.1	10.0	0.4	3	23	310	331	309	331	0.91
2	10	0.00016	0.012	16.2	0.5	6	23	340	357	340	357	0.99
3	10	9.7e-06	0.0007	20.0	0.3	1	23	363	386	363	386	0.98
4	10	0.00013	0.0096	16.4	0.5	1	23	398	420	398	420	0.98
5	10	0.00032	0.024	15.2	7.7	1	23	427	450	427	450	0.96
6	10	1.4e-05	0.00098	19.6	1.8	1	23	456	478	456	478	0.96
7	10	0.34	25	5.7	0.9	2	23	487	508	486	508	0.96
8	10	0.00013	0.0094	16.5	2.8	2	23	514	536	513	536	0.95
9	10	2.3e-07	1.7e-05	25.1	0.7	2	23	543	564	542	564	0.97
10	10	0.0002	0.015	15.9	4.4	1	23	570	593	570	593	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCCGTCTATCTGTTCGAAACGAACGACACCCTGGCCGAATCCTCGCTGCTCAAGATAATAGCCAAGTTTCTGCAGCTGGAGATAATGCCCGATGACAACATCTCGACGAACGTTTGCCACGATTGCTGCGAACATTTGGAGGACTTTAACAACTTCTGGCAGCTGGTCGAGCAAAAGCAATTAACACTTAAAAAGGAATTCCTCAATGTGGACGTCGACTGCGTGGCCCTGAAATGGACTGGCGGAATCGATGTCGATGTCAATATTGATGAACTGCCGCTGGTCACCGACGAGATGGACGAGAAGCCACTCGATATACACAATCTCAGTCTGCTCGGCAGCGTTCTCGATGTGAATGTGGACAGTGTGGAGGTGCCGCAGCTGCATGCTGCCCCAAAGCATTTGCACAATCCCGACCAGCTGCTGCCCCTGCACGCCTTCAATCCTGACGAAGATGATGTCGATGATgaagacaacgacgacgacgacgatgtgGATGAGAAACCCCTAATGAATGAGAGCAGCGATAGCACGCCGCACACTTCCTCAGATGATGATGATGAAGTACCTCTGGTGAAGCTGAAGCACAAGCTCAAACCAAAGCGGAAGGGACGCAATGAGCAGCGCCGGCTTACGCTCGCCCAGGAGCTGAATCAGCTGCTGGATGACACCGACACTGGATGCGATAATGAtaacgatggcgatggcgtcAATCGAGGGCGTCGCAAGCAGCgcaacacaaacagaaacacaatGAATAATGCCCCAACGGATACACAGAAGACCGAGCTGCAGGCGGCCATGGAACGGAAGCCAAAGGGCTGCTCGCGGGCGCAGTTATCGAAGCGGTACGAGGAGGCCATCGCCAGCTATATGAATGCCGACTGTGATCTGTGCGACTTCAGCACCAAGTACCTGTCCCAGTTGAAGGTCCACTTCCTGGAGGTGCATCAGCGTGACGCGTATCTCAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAACTGATGGATCACATACGCAAGCACATCAATCCCAAGCTATTCACCTGTTCGATTTGCAATAAGTCGCTAAATTCCCAGGATTATCTGGCCACGCACATTGAGACGGTGCACAACAAGGTCGCCCAGATTGGCAAGGTACTAAAGTATCCGTGCCCGAAATGCGAGCGCACCTTCAGTAGCGAGAGGCGTTTGGGTAATCATTTGCTGAAGCACGACACGGATCAATTGGAGCACAGTTGCCACATATGCCACAAGAGCTTTGCGAATGTGCACCGACTCCGTCGGCATATACAGTCGATCCATGAGGATGTGCATCCGCATGTCTGCGATATTTGTGGCAAGAAGTTCAAGTTTAAGCCATCGTTTGAGCGCCACTTGCTAGAACATCAGGGCGTCGTCGCACCAGCGATGGAGTGCTCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTTTGCGACTGCATCGATTTACGCACGATAGCACCGATACCGTCTGTCCCCATTGCTCCAAGACGTGCAGTTCGCGTACAGCGTTGCGCGCCCATGTTAAATATGCTCACAAGCTGACCACAAATCTGCAGTGCACTTATTGCGAGAAGACCTTCAAGCAGCAGCGCAACCTTGAGGAGCACATGGCGATACACACCGGCCTTCAGCTATACAATTGCCCCCACTGTCCCAAGGAGTGCAGGTCGCGCTCCAACATGTATGTCCACATCAAGCAGAGGCATGCGGACGAGTGGCTCAAGGCCAAAATGGCACGCTCCCACAATCCGCAGTTTAAGCCGCTCGCCTAA
Protein Sequence: MICRLCLKSINANNAVYLFETNDTLAESSLLKIIAKFLQLEIMPDDNISTNVCHDCCEHLEDFNNFWQLVEQKQLTLKKEFLNVDVDCVALKWTGGIDVDVNIDELPLVTDEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQLHAAPKHLHNPDQLLPLHAFNPDEDDVDDEDNDDDDDVDEKPLMNESSDSTPHTSSDDDDEVPLVKLKHKLKPKRKGRNEQRRLTLAQELNQLLDDTDTGCDNDNDGDGVNRGRRKQRNTNRNTMNNAPTDTQKTELQAAMERKPKGCSRAQLSKRYEEAIASYMNADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDVHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHVKYAHKLTTNLQCTYCEKTFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPLA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00553200;
80% Identity: -