Basic Information

Insect: Drosophila infuscata
Gene Symbol: Hr39
Assembly: GCA_035042205.1
Location: JAWNLR010000102.1:671895-675202[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.83 8.1e+03 -4.0 12.2 32 206 43 211 33 217 0.44

2 3 2 1.9e+04 -10.4 26.9 40 143 191 321 175 366 0.40

3 3 1.8e-101 1.8e-97 327.5 12.1 1 408 496 885 496 885 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.83	8.1e+03	-4.0	12.2	32	206	43	211	33	217	0.44
2	3	2	1.9e+04	-10.4	26.9	40	143	191	321	175	366	0.40
3	3	1.8e-101	1.8e-97	327.5	12.1	1	408	496	885	496	885	0.88

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTCTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAGAACATGTCGACGGCGACAGTGACGCCAGCGTCgccgcatcagcagcagcagcgtcacaATGTGTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTTATAGCCAactataataatcataatcacaatcacaatcacaatcatAGCGGCAGCTTGCGCATTCCCCTCGGTGGCAACGGGGATGAGTCCGATTCGGATGCGGAGTTGGCCAACATTGAGAATCTGAAGGTGCGAAGACGTGCGGCAGACAAAAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGCCGGCGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAGgtgagcagcagcaccagcagcagcagcagtgccacAACGATGGCCAGCAGTCAGGTGAACGCCATGTTGCAACCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcagcagcagcagcaacaacagcaacaacagcagcagcagcagcaacaacagcagcaacatcagcagcagcaccaactgcaacaccaacaactgcagctgcagcaacaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAACAACAAACTGAAACTGGCTCCGACGCAAAGTGATCCcatcaatttgaaatatgagccaacgacaacgacaacatctTCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCCATTTGCCACTGTTGCCCGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTATACGCCCTCGCTGAGCAGGAACAACAGCGATGCGTCGCACAGTAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCAATTCAGGCGCGTCATGCGCCACCCGCCGGCGTTGCTGCCTTGTTTAGCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTTTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTCAGCATGGATGCGGGTGGTGCTGCATTGGATGCCAGTGCAACGTTGGCTGCCTCGCCAGCGGGCATCTCGCGTCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGGTGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgtggcgGTCCCTGCCAGGTGAGCATCTCGACTCGCAAAAAGTGTCCCGCCTGCCGTTTCGAAAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGGCAGCCgctgcagccgcagccgccgttgtcaatcagcagcaacagcagcagcaacaccaacagcagcgacttcaacagcatcagcagcagcagcaacaacagcagcaacagcagcaacatggtCCACTCAATGGctttggtggtggtggctccAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAGCGGAGCAGCTTAATCATCATACGTCATCATCAACGCGAGCCTCAAGCATTCCACCTCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCGTTTGCAACTGGTGGCTCATCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCCTCCAATGGCGAGAACGCCAATCCCGATCTGATTGCGCACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATTTGCCTGCTAATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGATCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCCGAAAGATTACGCTGGCACAGGCTAAAACCAATGGTTTGCAGGCGTGCATTGAGCGGATGTTGAATCTGACCGATCATTTGAGACGACTGCGCGTTGACCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACCACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTCTGCAGGCCTACACTCTGGCCCATTATCCCGATACGCCGTCCAAATTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGAGcagattttaatttgctgATGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPASPHQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAAGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQHQQQHQLQHQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFSGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQQHQQQRLQQHQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQAEQLNHHTSSSTRASSIPPLLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00522221;