Basic Information

Insect: Drosophila incognita
Gene Symbol: hb
Assembly: GCA_035042225.1
Location: JAWNLQ010000719.1:7573418-7575949[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.00094 0.062 13.9 0.2 1 23 279 301 279 301 0.99

2 6 0.0076 0.5 11.0 4.5 2 23 309 330 308 330 0.97

3 6 0.00033 0.022 15.3 5.0 1 23 336 358 336 358 0.98

4 6 0.043 2.8 8.6 5.3 1 23 364 388 364 388 0.93

5 6 0.00026 0.017 15.6 0.4 1 23 790 812 790 812 0.96

6 6 0.0038 0.25 11.9 0.2 1 22 818 839 818 842 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.00094	0.062	13.9	0.2	1	23	279	301	279	301	0.99
2	6	0.0076	0.5	11.0	4.5	2	23	309	330	308	330	0.97
3	6	0.00033	0.022	15.3	5.0	1	23	336	358	336	358	0.98
4	6	0.043	2.8	8.6	5.3	1	23	364	388	364	388	0.93
5	6	0.00026	0.017	15.6	0.4	1	23	790	812	790	812	0.96
6	6	0.0038	0.25	11.9	0.2	1	22	818	839	818	842	0.91

Sequence Information

Coding Sequence: atgcagAACTGGGAGACGAGCACCGCAGCGCCCAATTATGAGCAGCACAATGCGTGGTACAGCAGCATGTTTGCCGCGAACATCAAGCAGGAGCCCATctcgcatcatcatcaccatcatcatgcCCATCACAGTCATCATGCtcacgacagcaacagcaacagcaatgcaaGCAGCCCGCACCAATCGCCGTTGCCCTCACCCAATCCGCCCAGCAACACCAATCTGCAACTGGAGCACTATctcaaacaacagcaacaacaacagcagcagcagcagcagcaacaacaacaacaacaacccatGGATACACTTTGTGGTGCTGCCATGACTCCATCGCCCAGCAACAATGATCAGAATAGCTTGCAACACTTTGATGCCAccctgcagcagcaaatcttgcagcagcagcaatatcagcAACACTTTCaggcagcacaacaacaacaacagcagcaacatcatcatctcACATTGGGCGGCTTCAATCCGCTGACGCCGCCCGGATTGCCCAATCCCATGCAGCACTATTATGCCAGCAATATGCGTCCCAGccccacagcaacaacagcaacggcagctgctgctgctccaacgacaacagcagcagcaattgcactGCAAGCCAATGACAAATTACAGGCACTAACGCCTCCCATGGATGTGACACCTCCAAAGTCACCGGCCAAGTCCCAGCAATCGTGTGCGGAGCCCGAGAAGGAGCATGATTTAATGTCCAATTCGAGCGAGGATATGAAATACATGGCCGAGTCGGAGGATGATGACACCAACATACGGATGCCCATCTACAATTCGCATGGCAAGATGAAGAACTACAAGTGCAAGACGTGCGGCGTTGTGGCCATTACCAAGGTGGATTTCTGGGCGCATACGCGCAACCACATGAAACCGGACAAGATACTGCAGTGCTCCAAGTGTCCCTTTGTCACCGAGTTCAAGCATCATCTGGAGTACCACATACGCAAGCACAAGAACCAGAAGCCGTTCCAGTGCGACAAGTGCAGCTATACGTGTGTGAACAAATCGATGCTCAACTCGCATCGCAAGTCGCACAGTTCGGTGTATCAGTATCGGTGTGCCGATTGTGATTATGCCACCAAATATTGCCACAGCTTCAAGCTGCATCTGCGCAAGTATGGTCACAAACCGGGCATGGTGCTGGACGAGGATGGCACACCCAATCCTTCGCTGGTCATTGATGTCTATGGCACCCGACGTGGCCCCAAAAGCAAATCGGTTCTGGGCAACGGCAACTCCAGCAACGGTTCCAgttccagcagcaacaagcgcGGCagtgcaacagctgccacagcagcactGCTGCACCAGCAACCAGTTattccagcagcaacatctcAGTTATCGGCTGCATTGCAAGGATTCCCAATGccagctgcggctgcagcaccagctgcagttgcaacaactgtGCCGCCTGTGTCGCCACCATCGCCAGCGAAGAGTGTTGCCAGCAGCGTTGAGCAGGCGCCCAGTTTGTCGAACGCTTTGCTGCCACCTTTGGCCAGCCTGTTGCAACAGAATCATCGCAACATGGCCTTCTTTCCCTACTGGAATCTCAATCTGCAAATGCTTGCCGCCCAGCAGCAGGCTGCAGTTCTTGCCCAGCTATCGCCGCGCATGCGtgaacagctgcaacaacaacaacagcagcagcaacatcagcaacaccagcagcaacatctgcaACAATTGCCCGCGCACAGCGAcaacgaggaggaggagcaggagccgGAGGAGGATGAAGCCGAGGATGATTTTGAGCGCAAATCGGTAGATTCAGCCATGGATCTGTCCCAAGGCACTCCGATCAAGGAggagccacagcaacagcagcgaacaCTGAACAATCACATGGCCATCAATTTAAAGATCAAGGACGAGGATACACCgctgatcagcagcagcagcgcctccCGACGCAAGGGCCGTGTGCTCAAGTTGGACAcgttgctgcagctgaagtCCGCCGCAATGTCCACGCCGGAGCAACAGCTCAAGTTGCCAGCGAGTGTGCTGCCCACCGCCTCATCTCCGATCTCTGGCAGCAGTGCAAACAAGCAGCTGGCGGACGACCCATGCTCGGGTGCCAGCTCAGCGGATGAGTCCATGGAGACCATGGGACATGCGCCGCAGGTCAATACCAGTGCCAGTTCAACGGCCTCCAGCTCCGGCAACAGCTcgaatgccagcagcagcagcaacccgactccagctgcaacagttgccgcctCAAGCTCAACCTCTACGTCCGCGTCTGCATCCGCATCTGCATCCGCGTCCGTGTCCAGCTCGtcctcgagcagcagcagcagctcaccGGCCATTTATGAGTGCAAGTATTGTGATATTTACTTCAAGGACGCCGTGCTCTACACCATCCACATGGGCTACCACAGCTGCGACGATGTCTTCAAGTGCAACATGTGCGGTGAGAAATGCGATGGACCCGTCGGACTCTTCGTGCACATGGCACGCAATGCCCACTCCTAA
Protein Sequence: MQNWETSTAAPNYEQHNAWYSSMFAANIKQEPISHHHHHHHAHHSHHAHDSNSNSNASSPHQSPLPSPNPPSNTNLQLEHYLKQQQQQQQQQQQQQQQQQPMDTLCGAAMTPSPSNNDQNSLQHFDATLQQQILQQQQYQQHFQAAQQQQQQQHHHLTLGGFNPLTPPGLPNPMQHYYASNMRPSPTATTATAAAAAPTTTAAAIALQANDKLQALTPPMDVTPPKSPAKSQQSCAEPEKEHDLMSNSSEDMKYMAESEDDDTNIRMPIYNSHGKMKNYKCKTCGVVAITKVDFWAHTRNHMKPDKILQCSKCPFVTEFKHHLEYHIRKHKNQKPFQCDKCSYTCVNKSMLNSHRKSHSSVYQYRCADCDYATKYCHSFKLHLRKYGHKPGMVLDEDGTPNPSLVIDVYGTRRGPKSKSVLGNGNSSNGSSSSSNKRGSATAATAALLHQQPVIPAATSQLSAALQGFPMPAAAAAPAAVATTVPPVSPPSPAKSVASSVEQAPSLSNALLPPLASLLQQNHRNMAFFPYWNLNLQMLAAQQQAAVLAQLSPRMREQLQQQQQQQQHQQHQQQHLQQLPAHSDNEEEEQEPEEDEAEDDFERKSVDSAMDLSQGTPIKEEPQQQQRTLNNHMAINLKIKDEDTPLISSSSASRRKGRVLKLDTLLQLKSAAMSTPEQQLKLPASVLPTASSPISGSSANKQLADDPCSGASSADESMETMGHAPQVNTSASSTASSSGNSSNASSSSNPTPAATVAASSSTSTSASASASASASVSSSSSSSSSSSPAIYECKYCDIYFKDAVLYTIHMGYHSCDDVFKCNMCGEKCDGPVGLFVHMARNAHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00547606;
90% Identity: iTF_00570685;
80% Identity: -