Basic Information

Insect: Drosophila incognita
Gene Symbol: ush
Assembly: GCA_035042225.1
Location: JAWNLQ010000727.1:3228539-3234981[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.054 3.6 8.3 0.0 1 20 193 212 193 214 0.89

2 9 0.00031 0.021 15.3 0.8 1 23 269 291 269 291 0.98

3 9 0.056 3.7 8.3 1.0 2 21 341 360 341 361 0.92

4 9 0.039 2.5 8.8 3.0 2 21 740 759 739 760 0.93

5 9 0.01 0.66 10.6 0.0 3 21 810 828 808 829 0.91

6 9 0.021 1.4 9.6 0.0 2 23 899 920 898 920 0.98

7 9 0.0043 0.28 11.8 1.3 1 23 926 948 926 948 0.99

8 9 0.0014 0.089 13.3 1.8 1 23 1017 1040 1017 1040 0.96

9 9 0.34 22 5.8 0.7 2 20 1150 1168 1149 1170 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.054	3.6	8.3	0.0	1	20	193	212	193	214	0.89
2	9	0.00031	0.021	15.3	0.8	1	23	269	291	269	291	0.98
3	9	0.056	3.7	8.3	1.0	2	21	341	360	341	361	0.92
4	9	0.039	2.5	8.8	3.0	2	21	740	759	739	760	0.93
5	9	0.01	0.66	10.6	0.0	3	21	810	828	808	829	0.91
6	9	0.021	1.4	9.6	0.0	2	23	899	920	898	920	0.98
7	9	0.0043	0.28	11.8	1.3	1	23	926	948	926	948	0.99
8	9	0.0014	0.089	13.3	1.8	1	23	1017	1040	1017	1040	0.96
9	9	0.34	22	5.8	0.7	2	20	1150	1168	1149	1170	0.91

Sequence Information

Coding Sequence: ATGGTCGACTGTTTGACTCTTCGACTGGCCGACAACCTCGATATGGGAGCCTTTGATTCCAAAGAATTGGCCGCACACGAGCTGAGCGAggagaagcaacagcaacaccagcagcaccaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCCTGCAACCCGTCGAGACTGACATGGACCAGGAACTGGAGGAGGCACAAGCGGCAGCCCAGGATTCCAGCGAACAGAAGTTGGAGGATAATCCGACAATGACAACGCCGCCGCGTAGCCCAACGCCCGAACTGGTGCCAAAGCTGGAGCGAGCTGATACGCCGCCCTCAGTTCCGGTCACGCCCAGTCCACCACCGCGTACGCCCACACCGCCGCCAATTGTGCTGCCAAAGCTGCGACTCAATGCGTTGCTTGCCTCCGATCCGGCATTGAAGCCCGATGCCAAGGAGCTCAATATGCACGAGTCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAACCGAGTCTGCAGCCGGATGTGGAGCCGCTGTTGAAACCGGCGCGATTTATGTGCCTGCCCTGCAGCATCGCTTTCAGTTCACCCTCAACACTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGGAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCcaatgccaacagcagctCCAGCGGCTCAAGTGCCACCGGCTCCGAGCCACCCAACAAGGTGTCCCGCATTGGCAAACAGTATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGACACATGCGCATGCATCAAACATCCCCAGCGGCACCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAATGGTGTTGTTGCCgcggctgctgccgccgctgcggcagctgccgctgctgctggtgcgcAGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGCGACGGACAACTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGAAGTGGAGTtggtggagctggagctggtggTGGGGGTGGAGCTGtatcagttgctgctgttgctgccggcaAGCACAGCCCACAGACGCGCAACAAGACGCCAACGCCAGCaatggttgctgctgccgccgccgcggctgcggctgctgctgcctcgctGCAGGTGGCACCACCGCAACCCTTCCTAGCGCTGCCCACCAATCCAATTATCATAGTGCCCTGCTCGCTAATACGTGCAGCCAGCTTGATACCTGGACCACTCACCACCTCTACGTCGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACAGCTCTAAACATAAATTCGCTAGGGGGCAGTGCCACGCCTACGCCTATGCCCAGCAGCAATCAGATACCGATTCCCGCTTTAGAGCCAGATCGTCCAACCCCTGTGAGCATTTCAAGCAACCTGGAAACGGAACCCAAGAAAAGTCCACCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACACCCCTGGATTTGTCGCTGAGGCGCTCGCCAATCTCTGCGCTATTGCAGCGCCAGCGTATCGCGCGCTCTGCCGCTGCGCTGCTGGACGCCGAGGATGCTGCAGGCAAGGATTCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCGGGAGCTGGGAGCGCTTCGTCGATGTCACCGCCAGCCCATCACATACTGGATAATTTGCCGCCGTTGCGCTCCATGCTGCCCTCCGACTTTAATCTCTCCGAATCGCTGCTGGCCAAAACGAATCCAGAACTGGCCCTCAAactggcggcggcagcagcggctgctgtggCAGGCAGTGGCTCGGCGGAGCTGGCTAAACTAGGATTTTCAGGAGGCGGTGCAGCAACCAGCAGTGGTGCTACTGCACCATCCTCTGCACAGAATGCACCACAGATCTATGTGAAGCAGGGCGTCTCCAAGTGTAAGGACTGCAATATTGTATTCTGCAAATATGAGAATTATTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAGGCGGGCCTGGATGGAGATGCCTCCAAGAGCGCTGTAACGCCCCCCAGTGGACTATCGTCAGTTGGTGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCCGCCTGTGGCATTAAGTACACCTCGCTGGATAATTTGCGTGCGCATCAGAATTACTACTGTTTGAAAGGAggcgctgcggctgctgcaacgCCAGCTgaggcagcaccagcaccacaacTGCCACTAGCCCATCCCAAGGAGAAGTGCCCAAAATGCAAGACTCATCATGAGCACGGACAGAATTGTccaccacctccaccaccGGCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTACCACGTCGAATAGTGTCAATAAGTGCCCCGTTTGTGGCGTAATTAGTCCCACAGCTGCCCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATCCGCACACATTTCGATAAGAAGACCAGCGATGTGAATGAGGAGCACTACATGACATGCATCTTTGAGGAAGAtgctgcagcagtggcagctaCAGTTGCTGCTCCAACTCAATCCTTGAATCTAGATCTGCCCGCtgtggcagcggcggcggcggcagcagcagcagcagcagcagcagctcaagaGCAACTGGAACAGCATCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTATAAGGGCAACGTGCTGCGTCACATGAAATTACTGCATCCACATGTGGCCATTAGTTCGCCTTCCATTTCACCCGAGTCGCGCGAACACGAAGCCAATCCTCATGCCCTACCCGAAATATCGCTGGTTAATGGGGAACGGGAGGCAGCATCTATGCCCATCTTCCACATTAAAACGGAGGCATTGGAGGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTGGCACACCACTTACCCACATTAAAGCAGAGCCCATGGAACTTGGTGTAGATGTGTCAGTACCGTCTCTACCCCCGCCGATGGCCAACTCCCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTAAAAACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCACTCCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGCAGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagaAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MVDCLTLRLADNLDMGAFDSKELAAHELSEEKQQQHQQHQQQQQQLEDQAEDEQLEQQSNNSSLQPVETDMDQELEEAQAAAQDSSEQKLEDNPTMTTPPRSPTPELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNMHESRLLGPPPKPEQQPSLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSSATGSEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAAAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGITGSGVGGAGAGGGGGAVSVAAVAAGKHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINSLGGSATPTPMPSSNQIPIPALEPDRPTPVSISSNLETEPKKSPPEPKRKETSGIRETTPLDLSLRRSPISALLQRQRIARSAAALLDAEDAAGKDSHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHILDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFSGGGAATSSGATAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQEAGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSTTSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAATVAAPTQSLNLDLPAVAAAAAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHALPEISLVNGEREAASMPIFHIKTEALEAPVATLSLVHENNNSPIGTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPLRPEANDSPSPTVGSGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -