Dimm004730.1
Basic Information
- Insect
- Drosophila immigrans
- Gene Symbol
- Aef1
- Assembly
- GCA_963583835.1
- Location
- OY757141.1:41127928-41129003[-]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0044 26 5.0 0.1 21 48 209 236 203 240 0.85 2 4 2.6e-05 0.15 12.2 0.0 21 52 237 268 234 270 0.89 3 4 0.03 1.8e+02 2.4 0.1 21 48 265 292 263 296 0.85 4 4 8.2e-05 0.48 10.6 0.1 21 47 293 319 289 326 0.88
Sequence Information
- Coding Sequence
- ATGATGCATATCAAGAGCCTGCCACACGCACATCAGGCCGCTGCGGCAATGAGCAATTGTGACATTGTCATTGTTGCCGCGCAACCGCAAACAAccagcgccaacaacaacaacaacgataccGTTACACAGGCCAGCCATGCCAACCATGTGGCGGCCGTTGCCCACGCCCAGCATcaggcacagcagcagcagcaacaacaacaacagcagcaacaacaacagcagcaacaacaacagcagcagcagcaacaacaacaacacaatcaacaacagcaacaacagccgccCGCGCCCACAGAAATCGCTTTGCCCTTTAATATGCATCTGTCGGGCATTGCACAGGAGGCGCACAGTGCCGCTCAAGCGGCCGCCATGGCAGCTGCGCAGGCCGCGGCAGCTcaagccgcagcagcagatcaacagcagcagcagccaccgcAGTCCTCAGCGACGCTGTCGCATCTGGTGGCGAGTGCAACGCATAGTCCGCCCACACAGCACGATGCTGGCCAGCATTATGTGACCAGCAATGGGCATGGCAACGATCCAGGCGCTGGCGAGGCGAACGGTTCGAATAGCAGCagtggaggcggcggcggcggtggcagtGGTGGTCGGGAGCAGGAGAAACCGTTCCATTGCACTGTGTGCGATCGACGCTTTCGGCAGTTGAGCACGCTGACCAACCACGTGAAGATTCATACGGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACGTTCCGTCAATCGTCCACGCTGACGAATCATCTGAAGATCCATACGGGCGAGAAGCCCTATAACTGCAACTATTGTCCCAAGCATTTCCGTCAGCTCAGCACATTGGCGAATCACGTCAAAATTCATACGGGTGAAAAGCCGTTCGAGTGCGTCATCTGCAAGAAACAATTCCGGCAATCGAGCACGCTCAACAATCACATAAAGATCCATGTCATGGACAAGGTCTATGTGCCTGTCAAGATCAAAACCGAGGAGGACGAGGGGTGA
- Protein Sequence
- MMHIKSLPHAHQAAAAMSNCDIVIVAAQPQTTSANNNNNDTVTQASHANHVAAVAHAQHQAQQQQQQQQQQQQQQQQQQQQQQQQQQHNQQQQQQPPAPTEIALPFNMHLSGIAQEAHSAAQAAAMAAAQAAAAQAAAADQQQQQPPQSSATLSHLVASATHSPPTQHDAGQHYVTSNGHGNDPGAGEANGSNSSSGGGGGGGSGGREQEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00610880;
- 90% Identity
- iTF_00589756;
- 80% Identity
- iTF_00520855;