Dimm010984.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila immigrans
Gene Symbol
Hr39
Assembly
GCA_963583835.1
Location
OY757143.1:20329005-20333195[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.48 2.8e+03 -2.7 0.1 146 176 18 48 4 106 0.57
2 4 3 1.8e+04 -12.7 26.5 37 147 177 305 164 339 0.44
3 4 1.6e-22 9.2e-19 68.1 1.8 1 130 493 650 493 662 0.87
4 4 6.4e-83 3.8e-79 267.0 0.4 183 408 673 889 668 889 0.96

Sequence Information

Coding Sequence
ATGCCCAACATGTCGAGCATCAAGACGGAGCAAAGCGTGTCTCCAGGCGCCAGCGGCGCCAGCTACCAGCTGCCCGTGAACATGTCCTCGACGCCCTCCTCCACCCGCCACAATGTCTCCGTGACGAACATCAAGTGCGAGCTGGACGAGCTGCCGACACCGAACGGCAACCTGGTGCCCGTTATAGCCAACTacaacaatcacaatcacaaccaTAATCACAATCATGGCGGCAGCCTGCGAATTCCGCTCGGCATGCAGGCGGCCAAGGAGGATGAGTCCGACTCGGAGCCGGAGCTGGCCAGCATTGAGAATCTGCAGAAGGTGCGACGACGTGCTGCCGACAAGAATGGACCGCGACCCATGTCCTGGGAGGGGGAGCTCAGTGAGCCCGAGACGGCGGTCGACGAGGAGCTGATGGACACGGAGACGGTCATCAAGAGCGAGGAGCGAAGCGGCGGCCAAGTGTCGGGCATGATGCAGCCCATCAAAACCGAGCTGGAGCACATAGCTGgcgaactgcagcagcaacagcaactgcagcacgagcagcatcatcatcatcatcaccatcagcaacaccatcatcatcagcatcagcatttgcagcagcagcagcagcagcagcagcagcatcaacagcagccacagcatctGCAGACCATCAAGCAGAACTTTGGCCAGCAGCCGAACAAACTGAAGCTGGCGCCGACGCAAAGTGATCCCATCAACCTGAAGTACGAGCCGACGTCATCGACGACGACGCTCTGCGATCGCAGCAAGTCCAACAGCGGCGGCCACTTGCCTCTGCTGCCCGCCAACCCCAGTCCAGATTCTGCCATACATTCCGTTTACACGCACAGCAgtccgtcgcagtcgccgctgACGTCGCGCCACGCCCCCTACACGCCGTCGCTGAgtcgcaacaacagcgatgCCTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCCATCCAGGCGCGTCATGCGCCACCCGGTGGCGCCTCCCTGTTGCCCTCGGCTAGCAGTTATGCCaatggcggcggtggcggcggtcCAGCTGCACTGCATCATCACAGTGTGCTGTATCGTCCGCTCAACGTGGAGCCACCGAACGCCGGCAGCTCGAGTGGTGGCCAGGAGGCGCAAAATCTCAGCATGGATGCCAGCGGCGCCGCATTGGATGCAACGGCTGCGCTGCCAGCCTCGCCGGCGGGCATCTCACGCCAGCAGCTGATCAACTCACCGTGTCCGATATGTGGCGATAAAATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCATGCAAGGGCTTCTTCAAGCGCACCGTTCAGAACCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAGAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAGCTGGAGGCCATACGCGAGGACCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGTTGCCCAACTCGATGCTCAGTCCGCTGCTCAGTCCAGATCAGGCggctgccgcagcagcagcggccgccGTCgtcaaccagcagcagcaacaacagcagcagcagcaacatcaccaGCGTTTgcaccagcaccagcaacagcatcagacACCGCAgacagcacagcagcaacacggACCACTCAACGGgtttggcggcggcggctgcagcgGTGGCAGCAGCGTTGGATCCAACTCCCTGCCGGCCAGTCCCAGTCTGGGCACATCTATCAAGACGGAGCAAGCGGAGCCGCTGAATCATCATGCGACGCGCGCCTCAAGCATTCCAGCCCTCCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATACACCGATGCCGAATTGGCTCGCATCAATCAGCCGCTGTCCTCATTCGCAACTGGCGGTTCCTCGTCAGGCTCTGGCGGAGGTTCGGGCACAGGGGGACATCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAATGGCGAGAACGCCAACCCCGATCTGATCGCCCATCTCTGCAATGTCGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATTTCGATTGACGATCAGATCTGCCTGCTAATCAACTCGTGGTGCGAGCTCTTGCTCTTCTCCTGCTGCTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGGAAGATTACCTTGGCTCAGGCGAAAACCAATGGCTTACAGGCTTGCATTGAGCGTATGTTGAATCTGACGGATCATTTGCGACGTCTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGATACCACGGAGCTACATGAGGCGGTCAAGGTACGAGAGTGCCAGGAGAAGGCGCTGCAGGGTCTGCAGGCATATACGCTGGCCCACTATCCCGACACGCCGTCCAAATTTGGGGAGCTATTGCTGCGCATTCCCGATCTGCAGCGCACATGTCAGTTGGGCAAGGAGATGCTGACGATCAAGACCCGCGATGGTGCCGATTTCAACTTGTTGATGGAACTGCTGCGGGGAGAGCATTGA
Protein Sequence
MPNMSSIKTEQSVSPGASGASYQLPVNMSSTPSSTRHNVSVTNIKCELDELPTPNGNLVPVIANYNNHNHNHNHNHGGSLRIPLGMQAAKEDESDSEPELASIENLQKVRRRAADKNGPRPMSWEGELSEPETAVDEELMDTETVIKSEERSGGQVSGMMQPIKTELEHIAGELQQQQQLQHEQHHHHHHHQQHHHHQHQHLQQQQQQQQQHQQQPQHLQTIKQNFGQQPNKLKLAPTQSDPINLKYEPTSSTTTLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPGGASLLPSASSYANGGGGGGPAALHHHSVLYRPLNVEPPNAGSSSGGQEAQNLSMDASGAALDATAALPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQQQQQHHQRLHQHQQQHQTPQTAQQQHGPLNGFGGGGCSGGSSVGSNSLPASPSLGTSIKTEQAEPLNHHATRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSGSGGGSGTGGHHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575636;
90% Identity
iTF_00614235;
80% Identity
iTF_00520679;