Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:10731762-10772195[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.5 86 3.4 0.9 3 21 474 492 472 496 0.91

2 14 0.43 24 5.2 0.4 2 23 518 540 517 540 0.91

3 14 0.039 2.2 8.5 1.0 1 23 557 580 557 580 0.95

4 14 0.28 16 5.8 0.5 1 22 585 606 585 609 0.90

5 14 0.029 1.7 8.8 0.2 2 23 660 682 659 682 0.92

6 14 0.42 24 5.2 0.1 1 21 687 707 687 708 0.92

7 14 2.5 1.4e+02 2.7 1.2 2 23 731 752 730 752 0.90

8 14 7.9e-05 0.0045 16.9 2.2 2 23 765 785 764 785 0.97

9 14 0.00024 0.014 15.4 1.5 1 23 791 814 791 814 0.97

10 14 0.00034 0.02 14.9 0.5 1 23 845 867 845 867 0.98

11 14 2.1 1.2e+02 3.0 0.2 1 23 874 898 874 898 0.89

12 14 0.16 9.2 6.5 4.0 1 23 903 927 903 927 0.97

13 14 0.00071 0.041 13.9 2.1 1 23 940 962 940 962 0.97

14 14 0.0019 0.11 12.6 4.6 1 20 968 987 968 989 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.5	86	3.4	0.9	3	21	474	492	472	496	0.91
2	14	0.43	24	5.2	0.4	2	23	518	540	517	540	0.91
3	14	0.039	2.2	8.5	1.0	1	23	557	580	557	580	0.95
4	14	0.28	16	5.8	0.5	1	22	585	606	585	609	0.90
5	14	0.029	1.7	8.8	0.2	2	23	660	682	659	682	0.92
6	14	0.42	24	5.2	0.1	1	21	687	707	687	708	0.92
7	14	2.5	1.4e+02	2.7	1.2	2	23	731	752	730	752	0.90
8	14	7.9e-05	0.0045	16.9	2.2	2	23	765	785	764	785	0.97
9	14	0.00024	0.014	15.4	1.5	1	23	791	814	791	814	0.97
10	14	0.00034	0.02	14.9	0.5	1	23	845	867	845	867	0.98
11	14	2.1	1.2e+02	3.0	0.2	1	23	874	898	874	898	0.89
12	14	0.16	9.2	6.5	4.0	1	23	903	927	903	927	0.97
13	14	0.00071	0.041	13.9	2.1	1	23	940	962	940	962	0.97
14	14	0.0019	0.11	12.6	4.6	1	20	968	987	968	989	0.95

Sequence Information

Coding Sequence: ATGAACTCGGAATCGGACGATCTGGAGGACACGCACCTGTGCATCAAGTGCAATGCGACGATTGTGGGTCTGCGCAAATACATAGATCATCGCAAGCAGAATTGTCTGAGCATTGCCGGCAACGAGCGCAAGGAGAAGCCAATGGTGGCCAGGACAACGACAGCTTCTGGTGCGGAGCATGCGGCGTCTGCAATCATAAGTCGCGCCAATTTGGAGCACAGCTACGATGGCTTTCACTTCGCAGAGCCGGAGGCGCCGAGCAGTTACTTGCGCAAGACGACGGCCAGCCATGGGGGCAAGACGTCCAAGGCCCTGACCGAGGCTTATGATCCTACCTACGAGCTGGGCGCTGATGTCTTCTTTTCCtcactgcagctgcagagcgTCTCGACGGGCGGCAAGACGGGTGCACGGCCCGAACGTGGCGCCAAGGAGGAGCACAACTGGCATTCATCCAGCAACTGCTCCGATCCACTGCTGAAGGCGGTGCGGGAACATGAGGAATCCGACTTTAAGCCGCTTAAGTTCGTGCACTCACCAGAGGCGAGCGAGGAAGAGGAGGATGACGAGGAGCCCGACGACTTTGATGGCGATGATGACGAAGCAGATCAGATGCacgagcaggagcaggagcaggaccAAGAACATGATCACGATCCTGATCCCGATGAAGATTACGATGGGCGACGCCACTCGCCGCCGACTGTGCCTGCCACGCACACAGGTGGCAAGTGGAAGCCGGAGCACCGACCACAGCTGCGCCACACGCATCTGGAACGCATCTCGCCCAGCTGGGATGAGCCGCCCGAGGATGCGCACGACCATCCACCCGCCGAGCACACGCACGGCAAGTGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGGGAAAACATTGATCTGaccaagctgcagcagccggaCGCCAGCTACTGGTGCAACATCTGTTGTCGCCGGCTCAAGACGCGCCTCAACTACGATCAGCATCTGCGCAGCGGCTACCATCTGCGGCGCGCGGATGCTGAGTGCCAATTGGAGCAGGCCAACCTCGAGTCCGCCAATCTGACGCTCAACAAGAACTTTGCCCAGCCGCCGGCTCCTGCCACGGAGCAACTGcatcgacgtcgtcgtcgtcgtgccAATCTCTTGCGCTGCGAACTGTGCCGCCACAGCATGGCGCGCCATCTCATGGGCAAGCACCTGATCTCCCACTATCACTATCGacgcctgcagcagcagcagcagctgcgcagcCAGAGCTCGCTGCACGCCATCCTGGAGCACATGGGCAGCATTGTGCGACAGGCGCCCTTCCAGTGCCTGCCCTGTCGATTCTATGCCAACACAGAGCAAACTTTTCAGGCTCATTGGCGCTCGTCTGCTCATGTGGAGCTGACCGAGCGACTTGGCGGCACTTTCTGGTGCAGCTACTGCCAGTTCGAGTGCGACAGCAACGAGGAGATGTGGCAGCATCTGCTGGGCAACACGCACAAGGAAGTGCTCTTTGCGATCAATCGATCGGTGCCCGTTTGCATTGCTCAGCGGCGTCTTCTGAGCTGCTCCGAGTGCAGCGCCAGCTTTCTCTACAATCTGCAGCTGCGGCGGCATTTCGCCTCGGAACATGCGGGAGTCGTGGCCACGGGCAGCGCCTCGGACGAGTACCAGTGTCGCTTCCGCTGCCAGATTTGCGGAGCTGCCCAAAGATCGCGCGTGGCACTGCAGCGCCACGAGAAGCACAAACATCGTCTGGCCAAATATTATTGCGCCCTTTGTCATCTGGAGTTCGAGACGCCGCTGGCTGCTCGCCGGCATCGCAATCTCATGCAGCACAAGCAGCATGCGAATCGTCGGAGCAGTCGCAAACGCAGCAGCCCCAAGCAACCGCCGCCCGAAATGGAAATTGAGCACATGCTGCGCGAGGTGCTGGAGGATGAGGCTGCGCAGCCGACGACGAGCTCCAAGGAGCGGCGTGCGAGCAGCCAATGTGTGAGCTGTCAGCTGAGCTTTGAGACGTCCCAAGCGCTGATTCAGCATCGCAGCGAAGCACATCCCATGGACAATCATGCCTGTCTCAGCTGTGGCGGCAGCTTCCAGTCGGCCCAGGCGCTGGGGCGGCACACGCGCAGCTGCCAGCCCATTGCCTCGACCTCGGCGGCTGCGTCGGCTCGTTCAGTGTCGCTCGCGAAGTCCTGGCACTGCGATCAGTGCGGCTTCAGTGCGCAATACGAATCAGATCTGCTCTATCATCGCTTCTTTCACACACGCGGCTCCTCCATTGGCAAGGACGAGCTGCTGCAGTGCCCGCTCTGCCCCAAGCAATTCCGCAAGCACTCGCTGCGTGCCCATCTGCGCAATCACACGAACGAACGCATCTTCGAGTGTGCCGAGTGCCTCTCCAAGTTCGCCAGGCGACACAATCTGAAGAACCACATGGCCACCATGCATGGCCAGCGGGCACAGACGAAGCCAGACGGCGCCCAGACAACAGCTAAGCAGACCACGACAAAGACGACGACAACGAAGCCCAAGCAGAAGTTTCAATGTGGCACTTGCGGCAAAATATTGGCCAAAAAaTATTCACTTAAACTGCACGAGATGAGCCATGCCACGCCGAAGCGGCAATTCCCTTGCCCCCACAAGGACTGCTCCTTCGCCGGTCTCACGCCGGAGGGCCTCAAAATCCATCTGAAGTCCCACTCACAGGGCACGCACAAATGTGAACGCGAGAACTGCAGCTACGTGGGCAAGAGTGAGCTGCACCTGAAGCGGCACCTCAAATCGCATTCGAGTGACCTAGAGCTGGCTGAGAGTGGCAAATGGTTCGCGTGCGATCAGTGCGAGTTCAAAGCGCGAGTCAAAGGTCACCTCAATCGTCACATGCGCCGACATACCGGAGAGAAGCCCCATAAATGTCCCCATTGCGACTTCCAGTGCAGCAGCTTCGACAATCTGCGCAAACACATCGTAAAGACAGGAAAACATCCAGGCAAGTTCATCTACGAGTGTTCGACCTGTACAGCTTTTAAGGGCAACAGCTTTAAGGACTATCAGATGCATTTGAGCACCCATAAGACGGAAAATCCATGA
Protein Sequence: MNSESDDLEDTHLCIKCNATIVGLRKYIDHRKQNCLSIAGNERKEKPMVARTTTASGAEHAASAIISRANLEHSYDGFHFAEPEAPSSYLRKTTASHGGKTSKALTEAYDPTYELGADVFFSSLQLQSVSTGGKTGARPERGAKEEHNWHSSSNCSDPLLKAVREHEESDFKPLKFVHSPEASEEEEDDEEPDDFDGDDDEADQMHEQEQEQDQEHDHDPDPDEDYDGRRHSPPTVPATHTGGKWKPEHRPQLRHTHLERISPSWDEPPEDAHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPDASYWCNICCRRLKTRLNYDQHLRSGYHLRRADAECQLEQANLESANLTLNKNFAQPPAPATEQLHRRRRRRANLLRCELCRHSMARHLMGKHLISHYHYRRLQQQQQLRSQSSLHAILEHMGSIVRQAPFQCLPCRFYANTEQTFQAHWRSSAHVELTERLGGTFWCSYCQFECDSNEEMWQHLLGNTHKEVLFAINRSVPVCIAQRRLLSCSECSASFLYNLQLRRHFASEHAGVVATGSASDEYQCRFRCQICGAAQRSRVALQRHEKHKHRLAKYYCALCHLEFETPLAARRHRNLMQHKQHANRRSSRKRSSPKQPPPEMEIEHMLREVLEDEAAQPTTSSKERRASSQCVSCQLSFETSQALIQHRSEAHPMDNHACLSCGGSFQSAQALGRHTRSCQPIASTSAAASARSVSLAKSWHCDQCGFSAQYESDLLYHRFFHTRGSSIGKDELLQCPLCPKQFRKHSLRAHLRNHTNERIFECAECLSKFARRHNLKNHMATMHGQRAQTKPDGAQTTAKQTTTKTTTTKPKQKFQCGTCGKILAKKYSLKLHEMSHATPKRQFPCPHKDCSFAGLTPEGLKIHLKSHSQGTHKCERENCSYVGKSELHLKRHLKSHSSDLELAESGKWFACDQCEFKARVKGHLNRHMRRHTGEKPHKCPHCDFQCSSFDNLRKHIVKTGKHPGKFIYECSTCTAFKGNSFKDYQMHLSTHKTENP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00531326;
90% Identity: iTF_00502875;
80% Identity: -