Basic Information

Insect: Drosophila hydei
Gene Symbol: -
Assembly: GCA_003285905.2
Location: NW:788044-792755[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00033 0.019 15.0 0.1 1 23 161 184 161 184 0.96

2 14 0.00018 0.01 15.8 2.3 2 23 233 255 232 255 0.97

3 14 0.011 0.63 10.2 0.9 1 23 361 384 361 384 0.93

4 14 0.53 30 4.9 3.9 2 23 433 455 432 455 0.95

5 14 0.0029 0.17 12.0 0.5 1 23 519 542 519 542 0.88

6 14 1.8 1e+02 3.2 0.1 2 14 561 573 560 585 0.85

7 14 0.00062 0.035 14.1 3.3 2 23 593 615 593 615 0.96

8 14 0.00073 0.042 13.9 0.1 1 23 714 737 714 737 0.95

9 14 7.5e-05 0.0043 17.0 0.3 1 23 789 812 789 812 0.93

10 14 0.001 0.059 13.4 2.2 2 23 862 884 861 884 0.97

11 14 0.0011 0.063 13.3 1.4 1 23 976 999 976 999 0.92

12 14 0.12 7 6.9 1.5 1 21 1051 1071 1051 1072 0.95

13 14 0.23 13 6.0 0.3 2 23 1114 1137 1113 1138 0.88

14 14 5 2.9e+02 1.8 0.6 1 13 1156 1168 1156 1180 0.71

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00033	0.019	15.0	0.1	1	23	161	184	161	184	0.96
2	14	0.00018	0.01	15.8	2.3	2	23	233	255	232	255	0.97
3	14	0.011	0.63	10.2	0.9	1	23	361	384	361	384	0.93
4	14	0.53	30	4.9	3.9	2	23	433	455	432	455	0.95
5	14	0.0029	0.17	12.0	0.5	1	23	519	542	519	542	0.88
6	14	1.8	1e+02	3.2	0.1	2	14	561	573	560	585	0.85
7	14	0.00062	0.035	14.1	3.3	2	23	593	615	593	615	0.96
8	14	0.00073	0.042	13.9	0.1	1	23	714	737	714	737	0.95
9	14	7.5e-05	0.0043	17.0	0.3	1	23	789	812	789	812	0.93
10	14	0.001	0.059	13.4	2.2	2	23	862	884	861	884	0.97
11	14	0.0011	0.063	13.3	1.4	1	23	976	999	976	999	0.92
12	14	0.12	7	6.9	1.5	1	21	1051	1071	1051	1072	0.95
13	14	0.23	13	6.0	0.3	2	23	1114	1137	1113	1138	0.88
14	14	5	2.9e+02	1.8	0.6	1	13	1156	1168	1156	1180	0.71

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCAATGTTTTCAACCGATTTCGATGAAGGCGATGGTGAGGCGGAGAGCCACAATAATGGTAATAACACGCTCACAGACGATTTTATaggagaggaggaggaggacgaaCAGGAGGCTGAAGAGGATGAGGGCTCGGCCGACGACAGAGGCAGCAAACGAAAAGGACACGAGCCCGATGACGATGccatatttgattttgaacTAGCGCCCCTTGTTAGCATTGCGGAACCAGAACTGGAACCGTTGCCTAGACCAACGGCGGCACTTCTGCAGCCTCCAATCCCAACGGTTGCAGCCGTCCGACCCCAGCATCGTCAGTCGTTGCCAGCTTCGTTTGGCTCCCAGCAAACGATGGGTCGTGGCAGTGCAGGTACAGCAACCACAAGGCCAACAACCTCACAGATCAATGCCACAGATGAGAACGGTCTGCCCATCAACTATGAACTGGGCGTTACCTATATATGCCCCGCCTGCGGCGCAGAGTATCGGCAGCAGGATTTGTGGAAGCGTCACATGAACCAGATGCATCAGTACAATACTCGGCGTGGTCTCAATTTCGTGGCCATTGACAAGCTGTATCATCGGTGTCTGGAGTGCAACAAGCGGATCGCGATGCACAGTCGAGAGAATTTGCTTAAGCACAAGTTCACCCACTTACCATTTCGGTGCACCAAGTGTCACATATGCAAGCGCGAGTACAAATACAGGCAGGACCTGATGGTACATTTGCGTATGGTGCACTGTGATGAGGTGGTGGCCATGATGCGTGGTGGCAAATTAAGTGCTGGGCGCAAGACGCGTGTTCGCGAGCCGCGCATTGAACATCACCGCGAACATTACGGACAGGCTAATGAAGATGATGGTGTAGAAGTCAAGAATGAGCTGATGGAAGCGGAGAGCAGTGCGCAGCCATCTGAAGAACCCAATCTCGACTTGGATGATGAACACAGTCACAGTTCAAATCAAGCGGCTATAAAAAAACGTAACACTGGTGTGGCAGGAAATGGCAGTGGAAATAACAGTGGTGCAGCTGATATTTGCGAGGACTATATACACTATATGTGTCCGGACTGTGGCACCGATTGTGATACACACGCCCAGTGGAGTCAGCATATTGAATTTGTACACGATTATGTCAGTCGCAGGGGTCTGAACTTTCGTTGCGttgatatgcaaatgcaatgccTCGAGTGCAAGCAGtttgtcaTTCCGAACACCATTAAGACGCTGCGCGCCCACAAGTTTAGCCACTTGCCCCAACCGGAGTGGATGCGCTGCAAACTGTGCTATAAGGGTTTTACGGAGCATCATGAAATACTAACGCATCTTCTTAAACAGCATAATTTGGAAACCTTAATGCCTgagaaggaggaggaggaacaGCAGCCCTTAGCTGTAGCCAGCGTGAGTGATGAGTATGAGGATAATCCTGGCATTGGCTGCGACGATGAAACTTCATTACATTGGGACGATGTGCCTCGTCGAGGTGGTCGTATTGGTAGCGATGATATGTACGAGCCGCATATTGATTATCTATGTCCGCAGTGCGGCAGGGAGTTCATAGAGAAGAAACATTGGCGCACGCATGTTGTCCAAGTGCACGGCATGAATGATCTGACCAAGTTGAATTTTGAGGTGATCAATGATCGCCAGTTAAAGTGCACCGAATGCGATAAGATAATAACGAATGCCTACGGCATACAGAATGCCCAGCAACATAGGATAACACATTTGCCCTACAAAGCCTACGCAAGATGCCGCAAATGCCATAAATCCTATACGGATCGCAAGGGTCTTGTCAAACATTTGGCTACTTACCATCGCGTGGGCTATGAGCCGCGCAAAACTGTTGGAACAGGTGCTGCTACTTTGACGCCAACCACAACACAGACGCCACGCAAGCAGATTGTCACCGTGGCCAATGAAACTTATGAGATTATCTATTTGGATGAGGAGCGATCGCCgcctaataataataatattaacgaAGAGAATGATTTTGGCGAGCAAATGCAAGCGGACGACGATGATTATGCCATAGGTAGTACCAGTGGAACAACGGGACGCCAGGCGCAAACACCTACTACTGCTGCACACAATCCTAATCCCAATCGCTATAAATGTGTAGATTGCGGCTCACTATTTGCCACACAGACAGCATTAAAGACGCACATCAGCGAAGAACATGATTTTATGGACACGCAATACAGTGCAAAAAAGTTTGACAATGCGGAGCCAACGGAGGACGCAGCTGTAGTACCTGTTGCCGTTACAAACACTGCAGGTGGTACGCCTGCAATGAACACCTCAGGTGCTTCCACCATAGAGCAGAATTATATATTCCTGTGCCCGTCGTGTGGAAAGGCCTATAAGACGCAGTTCGAGTGGCGACGTCACATCAACGAAGAGCACAATTTCGACAAGCGgcagtatttaaatatgcgcCAGCTGGACAAATATCGCTATCAGTGTACCCTCTGCAAGGATATTGTATGCAATTCAAAGCTGAAAGGCCTGCAGGATCATCACTTTCGGCATTTGCCTTACCGGTTATATCTGAAGTGCCTGGTATGCGGCACCTGCTACAATCACAAGCCCAACATTGCAGCGCATCTGCGCACACGACACAACATCTACGAGCGCGAGTCTTCTTCCTCATCTTGGCGTGACCAGCAGCAAAAGACCCAGAATGGCCACGAGCAGCCTAAgtataaggataaggataatgATAGGGATACGCAAGCCACAGTTGCCACCGGCACTAACTCTGCTTCACCTACACCCGGCAGTAGTCGCACGCTCAAGCCACAGCCGGGCGTGCTGCCCACACGACCTGCCGGTCTCAACACGTTGGAGGATAGTATATCGTATCATAATGCCGTGGATCTGGACTTTATTACTTATTATTGTCccaagtgcaataaaaattttgaCTCGCACGCCTTTTGGCGCAAACACATCGTAGAGATACACAACTATAATAGTCGGCAAGGTCTAAATTTTCGCCAGATTGACAACCATCACTATCTGTGCCTGGAATGCTATAAACGTGTGACAGTGACGCACACTAAGGGCGCTATCGGGCAGCTACAGTCGCACAAGTTCCGGCATTTGCCGTATCGCTCTTTCAAGTGCTTGACCTGCAGCGGGGAGTTTGTGCGCaagcaaatgtttttcaaGCATTTAAATCGTGACACCAATCGTTGCGACAACAAGCCATTAAGTGGCCAGGATGATGAGGATACAGCGGATCAGCCAGACAGGCCAGCTACCATGCTCGCCAAGGAGACACTTGATGTTGCGGCGTATCGTCTAATGTGTCCACAGTGCGGCGATGACTTTACCACCAGCAGCAAAGCTTTGTGGCGAGAGCACATTAACATCCATCATAGCTTGGGGAAGCGAGAGATGCTGCACATGCGCAAGCTAGGCGACGAACTTTATCGCTGCACTGACTGTGAAGAGCAGCTGGAAACGAAGCATCTGCGAGTGCTACAGCAACATCGCTTTCAGCATTTGCCGTATGCCGCGTATATTCGCTGCCAGCTATGCGAACAGCAGTCGGCGGATGAGGTGGGTCATGGTGTAGCGTCTGCCGGTTTACATAGTATGCGCGAACTGCAGCAACACATACGCAACGAACATCCGGATGTGGTTGAGCAGAACGAGCAAATGCAAGCACTACTCGACGAGGAGGAGGATAGTCAGAAGCCAGCGGCTAGCAATGAAACAACAGACACTGGTCTATAcatgccgctgccgccgcatTTGCTAGACGATGATGTGGAGGACATGGAGTTCGAGGAACAGTATCTGCTAGGCTAA
Protein Sequence: MEGMDLWTSMFSTDFDEGDGEAESHNNGNNTLTDDFIGEEEEDEQEAEEDEGSADDRGSKRKGHEPDDDAIFDFELAPLVSIAEPELEPLPRPTAALLQPPIPTVAAVRPQHRQSLPASFGSQQTMGRGSAGTATTRPTTSQINATDENGLPINYELGVTYICPACGAEYRQQDLWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCHICKREYKYRQDLMVHLRMVHCDEVVAMMRGGKLSAGRKTRVREPRIEHHREHYGQANEDDGVEVKNELMEAESSAQPSEEPNLDLDDEHSHSSNQAAIKKRNTGVAGNGSGNNSGAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYKGFTEHHEILTHLLKQHNLETLMPEKEEEEQQPLAVASVSDEYEDNPGIGCDDETSLHWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLTKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKTVGTGAATLTPTTTQTPRKQIVTVANETYEIIYLDEERSPPNNNNINEENDFGEQMQADDDDYAIGSTSGTTGRQAQTPTTAAHNPNPNRYKCVDCGSLFATQTALKTHISEEHDFMDTQYSAKKFDNAEPTEDAAVVPVAVTNTAGGTPAMNTSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERESSSSSWRDQQQKTQNGHEQPKYKDKDNDRDTQATVATGTNSASPTPGSSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEIHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCSGEFVRKQMFFKHLNRDTNRCDNKPLSGQDDEDTADQPDRPATMLAKETLDVAAYRLMCPQCGDDFTTSSKALWREHINIHHSLGKREMLHMRKLGDELYRCTDCEEQLETKHLRVLQQHRFQHLPYAAYIRCQLCEQQSADEVGHGVASAGLHSMRELQQHIRNEHPDVVEQNEQMQALLDEEEDSQKPAASNETTDTGLYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00532646;
80% Identity: -