Basic Information

Insect: Drosophila hydei
Gene Symbol: ush
Assembly: GCA_003285905.2
Location: NW:3437548-3497331[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0057 0.33 11.1 0.0 1 20 208 227 208 229 0.90

2 9 0.00025 0.014 15.4 0.8 1 23 284 306 284 306 0.98

3 9 0.044 2.5 8.3 1.0 2 21 351 370 351 371 0.92

4 9 0.043 2.4 8.3 2.9 2 21 748 767 747 768 0.93

5 9 0.0079 0.45 10.6 0.0 3 21 817 835 815 836 0.91

6 9 0.0057 0.32 11.1 0.0 2 23 895 916 894 916 0.98

7 9 0.0033 0.19 11.8 1.3 1 23 922 944 922 944 0.99

8 9 0.0012 0.067 13.2 1.9 1 23 999 1022 999 1022 0.96

9 9 0.26 15 5.8 0.7 2 20 1129 1147 1128 1149 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0057	0.33	11.1	0.0	1	20	208	227	208	229	0.90
2	9	0.00025	0.014	15.4	0.8	1	23	284	306	284	306	0.98
3	9	0.044	2.5	8.3	1.0	2	21	351	370	351	371	0.92
4	9	0.043	2.4	8.3	2.9	2	21	748	767	747	768	0.93
5	9	0.0079	0.45	10.6	0.0	3	21	817	835	815	836	0.91
6	9	0.0057	0.32	11.1	0.0	2	23	895	916	894	916	0.98
7	9	0.0033	0.19	11.8	1.3	1	23	922	944	922	944	0.99
8	9	0.0012	0.067	13.2	1.9	1	23	999	1022	999	1022	0.96
9	9	0.26	15	5.8	0.7	2	20	1129	1147	1128	1149	0.91

Sequence Information

Coding Sequence: ATGTCACGACGCAAACAGTCGAATCCAAAGCCGTTGAATAAAGGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGATTTGGGCGCACACGAGCTGAGCGAggagaaacaacagcagcagctggaggagcagCCCGAGGACGAGCAGCtggatcagcagcagcaagcaagcAACGCCGCTGAACAGATCGAGGAGACTGACATGGATCAGGAAATGGTTGAGGAGGAGCAGGCAGCCGCCCAGGAGGCCagtgcacaacaacaaaatgtggcCGACAGCTCGACGACTCCACCACGTAGTCCCACGCCACCTGAACTCGTGCCCAAGTTGGAGCGTGCCGATTCGCCGGCAACGCCGCCTTCAGTggcagccacgcccagtcCGCCACCAACGCCCACGCCGCCCTTGGTGCTGCCCAAGCTGCGTCTCAATGCGCTGCTCGCTTCCGATCCGGCTCTTAAGCCCGATGCCAAGGAGCTAAATTTGGAGCCACGCTTGCTCGGTCCGCCGCCGCAGCTGGCAAAGCCtgagcagtcgcagcagcagcagagcttaCCGGATCCAAGCAGTCTAGTGGAGCCGCTGCTCAAGCCGGCGCGTTTTATGTGCCTGCCCTGCGGCATAGCTTTCAGCTCGCCTTCAACGCTGGAGGCGCACCAGGCCTACTACTGCTCGCATCGCAACAAGGATGCCGACGAGGAGTCGGCCACCGGCGACaaggcagcagccgcagctgctggcggcggcaatccaaatgccagcaacagctccagcGGCGGCAGCTCCGGCTCGGAGCCACCAGCCAAGGTAGCGCGCACGGGCAAGCAGTACGCCTGCACGCAGTGTTCCTACAGCGCCGACAAGAAGGTCTCCCTCAATCGCCACATGCGCATGCATCAGACCTCGCCAGCAGCGCCCACCCTGAACAGCCTGTCCGGGTTGGCCGCCAACGGTGTGGCTGtggccgccgccgccgctgccgctgcggccAGCGCGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATACGCTTCAACAACATCAAGACCTATCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGCGACGGCCAGCTGACGCCCAAGCCCGAGGCGAACAGCACTGGCAACACGGCAGGCTCTGCAGTGGGAGTTGCCGCCGCGGCGGCCAAGCACAGCGGCGCTCACAGTCCGCAGACGCGCAACAAGACGCCGACGCCTGCTATGgtcgcggctgctgctgctgcggctgccgctgctgcagcggccgcCTCGCTGCAGGTGGCACCGCCGCAGCCCTTCCTGGCGCTGCCCACCAATCCCATCATCATAGTGCCCTGCTCGCTAATACGCGCAGCCAGCCTCATTCCAGGACCACTCACCACCTCCACGTCGGGTATTGTCAATCCGGAGTCCACGTGCTTCACCCTTGACAATGGAGCACTCAAGCCGCTGGCCACGGCGCTCAATATAAATGCGCTGGCAggcaatgccacgcccacgccaacGCCCACACCCATGCCTAGCAGCAATCAGCTGAGCATGCCCGCCCTGGAGCCAGAGCGGCCCAGCGCCAGCAGCGTCTTGGAGGCGGAGGTCAAGAGCAGTCCGCCAGAGCCCAAGCGCAAGGAAGCCAGCGGCGTACGCGATACCACGCCCCTAGACTTGTCGCTGCGTCGTTCGCCAATttcgccgctgctgcagcgccaCCGCTTGATGGAGGAGGCGCTGCTCAGCGCCGGCAAGGAGAGCCTGGAGAGCAGCGCCAGAACTGGTGGCAGCGTTACGCCGGAACAGATTGTGTGCGCGCCCTCGCTGCCCAGCAGCCCATCGATGAGTCCCTCGCCCAAGCGACGTGCGATCAGTCCACGCAGCTCTGGGGCGGGTAGTGCTTCCTCCATGTCGCCGCCAGCCTTGGCAGTGCCCCATCTGCTGGACAACCTGCAATTGCGCTCAATGTTGCCCGCCGACTTTGCACTATCCGAATCGCTGCTGGCCAAGACCAATCCGGAGCTGGCGCTGAAGttggcagcagccgccgctgcagctgtggcGGGCAGCAGCCCCGCCGAGCTGGCCAGCAAACTAGGCTTCAGCCCAGCAACTGGGCCTGCACCTCCTCCGGCTGTGGCTAGCGTGGCAGCCAACGCGTCCAACAGCCAGCCGCAGATCTATGTGAAGCAGGGCGTGTCCAAGTGCAAGGAGTGCAACATAGTCTTCTGCAAGTACGAGAACTATCTGGCGCACAAGCAGCACTACTGCTCCGCGCGCAACCAGGACACAGGTGCGGATGGTGACGTCAAGAATGCAGTGACACCGCCCGCCGCACCGGGTCCAGGCGTAGCCGGGTCCGGTGCCTCCGCGCTGGAGACCACGCCCGTGGCCTATCAGCAGCTGATCTGCGCCGCCTGTGGCATCAAGTACACCTCGCTGGATAATCTGCGCGCACATCAAAACTACTATTGCCCCAAGGGCGGAGCGGCAGCCACGCCAGCCGAGGCAGCCACACCACAGCTGCCATTGCCCAAGGAGAAGTGCGTTAAGTGCAAGACACTGCATGAGCATGGCCAGCcctgtgccacgcccccagccGCGCCCCAGCTGCCGCCGGCCAGTGTGGCGAATAGCGTGAACAAGTGTCCCGTTTGCGGTGTGGTCAGCCCCACCGCTGCGCTGGCCCGCAAGCACATGGAAATGCACGGCACGGTGAAAGCATTCCGTTGCAGCATCTGCCAGTATAAGGGCAATACGCTGCGCGGCATGCGCACCCACATACGCACCCATTTCGATAAGAAGACGAGCGATGTCAACGAGGAGCACTACATGACCTGCATCTTCGAGGAGgatgcggcagctgcagcggcaccGCTACCCCCGGCCATGGGCTTGGACCTGCCCGCCGTGACAGCGGCCCAGGAACAGCTGGAACAGCACGCGGCACAGATCTTCAACTGCGATCACTGCAACTATGCCTCCACCTACAAAGGCAATGTGCTGCGTCACATGAAACTGTTGCATCCACACGTGGCAATCAACTCGCCCTCCATATCACCCGAGTGCCGTGAGCAGGATTCCACAGCACATGCCCTGCCCGAGGTAGCCCTGGTAAATGGCGAGCGCGAGGCGGCCAGtTTCCACATTAAGTCGGAGCCCTTGGAGCCACCTGTCGCTACATTGGGTCTGGTGCATGAGAACAACAATTCGCCCATTGGCACGCCGCACACGCACATCAAAGCCGAGCCGCTGGACATGGGCATTGAGCTAACCGCACCCACACTGCCACCGCCCATGGCGAATTCGCCGCTGGGGCCGAGCGCCGCGGAGGCCATGAAGAAATATTGTTCCACCTGCGACATATCGTTCAACTATGTGAAGACCTTTTTGGCACACAAACAGTTCTACTGCAAGAGCAAGCTACACCGACCGGAGGCCAGTGACAGCCCCAGTCCCACTGTGGGCGTTGGTGGCACCGCCATGCCACTGCAGTCGCCCagcgagctgctgttgctgcaaaagAACAAGGAGAATCTTCAGGAGGCGGCCATTTGA
Protein Sequence: MSRRKQSNPKPLNKGDCSDTTEEMTVDSRDSKDLGAHELSEEKQQQQLEEQPEDEQLDQQQQASNAAEQIEETDMDQEMVEEEQAAAQEASAQQQNVADSSTTPPRSPTPPELVPKLERADSPATPPSVAATPSPPPTPTPPLVLPKLRLNALLASDPALKPDAKELNLEPRLLGPPPQLAKPEQSQQQQSLPDPSSLVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRNKDADEESATGDKAAAAAAGGGNPNASNSSSGGSSGSEPPAKVARTGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPTLNSLSGLAANGVAVAAAAAAAAASALEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEANSTGNTAGSAVGVAAAAAKHSGAHSPQTRNKTPTPAMVAAAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINALAGNATPTPTPTPMPSSNQLSMPALEPERPSASSVLEAEVKSSPPEPKRKEASGVRDTTPLDLSLRRSPISPLLQRHRLMEEALLSAGKESLESSARTGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPALAVPHLLDNLQLRSMLPADFALSESLLAKTNPELALKLAAAAAAAVAGSSPAELASKLGFSPATGPAPPPAVASVAANASNSQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQDTGADGDVKNAVTPPAAPGPGVAGSGASALETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAAATPAEAATPQLPLPKEKCVKCKTLHEHGQPCATPPAAPQLPPASVANSVNKCPVCGVVSPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAAAAPLPPAMGLDLPAVTAAQEQLEQHAAQIFNCDHCNYASTYKGNVLRHMKLLHPHVAINSPSISPECREQDSTAHALPEVALVNGEREAASFHIKSEPLEPPVATLGLVHENNNSPIGTPHTHIKAEPLDMGIELTAPTLPPPMANSPLGPSAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPTVGVGGTAMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598429;
90% Identity: iTF_00532635;
80% Identity: -