Dhet002271.1
Basic Information
- Insect
- Drosophila heteroneura
- Gene Symbol
- -
- Assembly
- GCA_035042245.1
- Location
- JAWNLO010000162.1:764029-767584[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 0.14 8.7 6.9 0.0 1 13 355 367 355 375 0.81 2 8 0.0004 0.026 14.9 1.5 1 21 726 746 726 747 0.95 3 8 0.00086 0.055 13.8 3.4 1 23 764 786 764 786 0.97 4 8 0.00011 0.0068 16.7 6.5 1 23 792 814 792 814 0.97 5 8 3.8e-05 0.0024 18.1 0.9 1 23 820 842 820 842 0.98 6 8 0.00061 0.039 14.3 1.4 1 23 848 870 848 870 0.98 7 8 0.011 0.72 10.3 0.0 2 23 877 898 876 898 0.96 8 8 0.017 1.1 9.7 0.1 3 21 906 924 904 925 0.91
Sequence Information
- Coding Sequence
- ATGACGCCAGCAGCTGTTGAGGATGGGCGTGAGAAATGCGGCAGCGTCTACACTTGGAACTGTGCTGGCGAACTCTATGGCATCGAGTGTGAGCTGTGCGAGGAGCGACCCCTTTGTGCACTCGATGAGTTTGCCGAGCATATGGAGCTGTGGCACTCCGACTGGCAACAGGCACCGGAGGATGAGCTTATGCAGGAGGTCCTCGCCGAACAGTCCAGCAGCAACTGCGAGGTCAATGAACTCAAACAGCAGCTGGTTCAAGAGCTCAACTCACACgataaacagcaacagcaaccacagcagcaaccacagcagcagccacagcagcagccacagctgaTGGACACATTTCAACTGAACGATCAAGTTCAGTTCAATGCGGATaGTGGCCTGCCCAGTGTGGAAACGGCAGCGAAGCTGACGACGGAGCATGTGCAGCAGCTGATTGAGCTATATCGATCGCATCCGCGACTGTGGGATCAATCGCATCCAGAGTTCCGGGACGTGGAGCAGTGTCGCCACTCGTGGCGCCAGATAACGGATGCGTGGAGTGCCCACTGTGGACGTGGCTTCAGTGTGACCGATGTGCGCATCCGGATCTCAACGCTGTGCCAGCGATTCCTCAAGCAGCGTGAACGCATCGATGCCGAGGGTGATCTCGATGAGGGCGCCAAATTCGTCCACTACGATCAGTTGCGTTTCCTCTGTGAGCAGCAGGCGCTGCTGAAGCGCCAGGAGCACTTTGCCCGCGAGAATCGCAAACTGCTCGAGATCTACGAGCATTATCCAATACTCTGGCACAATGCCCACAAGCGATTGCGCTGCGCCGCAACGGTGAAGAGGCGCCACGAGGCACACCGTGGCCTCCAGCTGGCGTTGCGTATGTGCGGCATTAATCTGTCCGGCTTGGCGATGCAGCGGCGACTCCAGTCGCTGAGGAAACGCTATCGCCTGGAGAAGATACGCTATCTGCACAGTGTCGTCGAGGGCAAACAATCGGAGTTTGTGTCCATCTTTGAGCATTATGCCGAAATGGAGTTTCTGCACAAGCACATCGATCCCTATGTCTGTGCTGGCTGCGGCAAGATCTTTGAGAATCTGATTGGTCATCAGGCGCATGTGCAAGATAGCTGCGAGGAGCAATCGCTGGCTGCAGCCGATTGCAAACAGTTGACCGAATCGGAGGCGACGCTGGGCGAGCTTATggtgcagctggagcagcacgaattacagcagcagcaacagcaacaccagcagcagcagcagcagcagcaacagcagcagtctgTCGGAGAAGAAACCGAGCAGCTGCAGGTAGTGGAGCAAgtggaacagcagcaggaccAGCTGGTGGCAGCTGCATCTACAACTGAGCTGGCCACGCCACTGCTGCATAGTCTAGCCGAACAGGAGGACGCGCAGCAGGTGGAGATTGAGCAGCATCCTGACAAAGAAGATCCGCACGGCAAGGAGTCCTTCTCCGAGGATAGCCTGTCGACGGGTGGACAGCTACGCATGCGCCTCAGCCTGGAGCTGACCAATAAACTGATTGAGCTCTATCAATCGCATCCAAATCTCTGGGATCCCAATCATCTGGACTATCATGCGAGGAAACAGCGACGCCAGGCCTGGCACAACATTGCCGCCCAGCTGAATACATTTGCCGGCTGTCCGGACCGCTTCAGCTGGCAGATGCTGCATCGCAAGCTCACCGACTATGTCAAGTACTATCGACGCGAACGCCAGCGAGAGGAGCTGGCGGTTGGAGGTGGTGGCGAGGGCACACGTTGGGGCTTCTACGAGGCGTTCAGCTTTATGGACGATGTGGTCCCGATAAATCGTGTGCTGCAGAAATCATTGCAGCAGCGCGACAGCAATCTGAAGATCATCCAGGTGTATCAGAGCTACGAGCAGCTGTGGTGCACCACACATCCGGATTACACGAAACGTAAGCAGCGCTTGCGGCACCTGGAATCGCTGTGCACCCGCCTGCAGGAGGAATGCAATCTGCAGATAACCGTTGAGCGTTTGAAGAGTCGTCTGATCGAGTTTCGCTGCCAGTATCGTCAGTGCAAGGAGGCACGCCAGGCGGCGCTGCAGCGCAACAATGCCAACTGGCAGCCGACCTATGAGTATTATGCGCCGTTGCAGTTTCTCGAACTGCACGTGTCGCCGTTCAACTGCGAACGGTGCACGGCGAGCTTTAAGCGGCGCAGCGATTATCTGCGGCATCAGCGCAACCGACGCCGTCGCATGCGACGTGGCACGAATGCGACAAATCCGCTGGAGCACATCTGTCACATTTGCGCGATGAAATTCTCGTTGCGCACCAGCCTCCAGGCGCATCTGCGTCGCCATTTGGGGCAGCGGACGCACTGTTGCACCGACTGTCCCAAGAAGTTCTTCAATTCGACATCGTTGCGGGTGCATCAGCGCAGCCATACCAAAGAGCTGCCGTATGTGTGCGAGCATTGTGCCCGGGGCTTTGTCAATGCCAGCAAACTGAATCAGCATGTTAAGCGGCATACGGAGAAACGGGATTATCCGTGCACCCGCTGCGACAAGGCGTTCTATACGGCACACGAGCGAGATCGCCACTTGCGCGCCCATCTCAACATTAGGGACAAGGTGTGTCCGTATTGCAGTCGGGCCTTTGTCGTTGGCAGCGCCTATTATGCCCATCTAAATTTGCATCGGGGCGAGAAGCGTTATGGCTGTGCCGCATGTGGCAAGCGATTCGCTCAGTATGCGGGTCTCTATAAGCATCGCAAGCGCTGCACAATCGCCCAGCTGCAGGAGAAGTGa
- Protein Sequence
- MTPAAVEDGREKCGSVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHSDWQQAPEDELMQEVLAEQSSSNCEVNELKQQLVQELNSHDKQQQQPQQQPQQQPQQQPQLMDTFQLNDQVQFNADSGLPSVETAAKLTTEHVQQLIELYRSHPRLWDQSHPEFRDVEQCRHSWRQITDAWSAHCGRGFSVTDVRIRISTLCQRFLKQRERIDAEGDLDEGAKFVHYDQLRFLCEQQALLKRQEHFARENRKLLEIYEHYPILWHNAHKRLRCAATVKRRHEAHRGLQLALRMCGINLSGLAMQRRLQSLRKRYRLEKIRYLHSVVEGKQSEFVSIFEHYAEMEFLHKHIDPYVCAGCGKIFENLIGHQAHVQDSCEEQSLAAADCKQLTESEATLGELMVQLEQHELQQQQQQHQQQQQQQQQQQSVGEETEQLQVVEQVEQQQDQLVAAASTTELATPLLHSLAEQEDAQQVEIEQHPDKEDPHGKESFSEDSLSTGGQLRMRLSLELTNKLIELYQSHPNLWDPNHLDYHARKQRRQAWHNIAAQLNTFAGCPDRFSWQMLHRKLTDYVKYYRRERQREELAVGGGGEGTRWGFYEAFSFMDDVVPINRVLQKSLQQRDSNLKIIQVYQSYEQLWCTTHPDYTKRKQRLRHLESLCTRLQEECNLQITVERLKSRLIEFRCQYRQCKEARQAALQRNNANWQPTYEYYAPLQFLELHVSPFNCERCTASFKRRSDYLRHQRNRRRRMRRGTNATNPLEHICHICAMKFSLRTSLQAHLRRHLGQRTHCCTDCPKKFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEKRDYPCTRCDKAFYTAHERDRHLRAHLNIRDKVCPYCSRAFVVGSAYYAHLNLHRGEKRYGCAACGKRFAQYAGLYKHRKRCTIAQLQEK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01322149;
- 90% Identity
- iTF_00499824;
- 80% Identity
- -