Basic Information

Insect: Drosophila heteroneura
Gene Symbol: Znf639
Assembly: GCA_035042245.1
Location: JAWNLO010000094.1:160472-163599[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.015 0.93 10.0 0.4 3 23 313 334 312 334 0.91

2 10 0.00016 0.01 16.2 0.5 6 23 343 360 343 360 0.99

3 10 9.4e-06 0.0006 20.0 0.3 1 23 366 389 366 389 0.98

4 10 0.00013 0.0082 16.4 0.5 1 23 401 423 401 423 0.98

5 10 0.00032 0.02 15.2 7.7 1 23 430 453 430 453 0.96

6 10 1.3e-05 0.00084 19.6 1.8 1 23 459 481 459 481 0.96

7 10 0.33 21 5.7 0.9 2 23 490 511 489 511 0.96

8 10 0.00013 0.008 16.5 2.8 2 23 517 539 516 539 0.95

9 10 2e-07 1.3e-05 25.3 0.7 2 23 546 567 545 567 0.97

10 10 0.0002 0.013 15.9 4.4 1 23 573 596 573 596 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.015	0.93	10.0	0.4	3	23	313	334	312	334	0.91
2	10	0.00016	0.01	16.2	0.5	6	23	343	360	343	360	0.99
3	10	9.4e-06	0.0006	20.0	0.3	1	23	366	389	366	389	0.98
4	10	0.00013	0.0082	16.4	0.5	1	23	401	423	401	423	0.98
5	10	0.00032	0.02	15.2	7.7	1	23	430	453	430	453	0.96
6	10	1.3e-05	0.00084	19.6	1.8	1	23	459	481	459	481	0.96
7	10	0.33	21	5.7	0.9	2	23	490	511	489	511	0.96
8	10	0.00013	0.008	16.5	2.8	2	23	517	539	516	539	0.95
9	10	2e-07	1.3e-05	25.3	0.7	2	23	546	567	545	567	0.97
10	10	0.0002	0.013	15.9	4.4	1	23	573	596	573	596	0.96

Sequence Information

Coding Sequence: ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCTGTCTATCTGTTCGAAACGAACGACACGCTGGCCGAATCCTCGCTGCTCAAGATAATAGCCAAGTTTCTGCAGCTGGAGATAATGCCCGATGACAACATCTCGACGAACATTTGCCACGATTGCTGCGAACATTTGGAGGACTTTAACAACTTCTGGCAGCTGGTCGAGCAAAAGCAGTTAACACTTAAAAAGGAGTTCCTTAACGTAGACGTCGATTGCGTGGCCCTCAAATGGACGGGCGGTATCGATGTGGATGTCAACATAGATGAGCTACCGCTGGTCACCGATGAGATGGACGAGAAGCCCCTCGATATACACAATCTCAGTTTGCTCGGCAGCGTCCTCGATGTGAATGTGGACAGTGTGGAGGTGCCGCAGCTGCATGCTGCaccaaaacttttgcataaCCCCGACCAGCTGCTGCCCCTGCACGTCTTCAATcctgacgatgatgatgacgacaacgacgacgatgtcGATGAGAAGCCCATAATGAATGAGAGCAGCGATAGCACGCCGCACACTTCCTCAGATGATGATGATGAAGTGCCTCTGGTGAAGCTGAAGCACAAGCTCAAACCAAAGCGGAAGGGACGCATTGTGGCACGCAATGAGCAGCGCCGGCTAACGCTCGCTCAGGAGTTGAATCAGCTGCTGGATGACACCGACACTGGAtgcgataacgataacgatggCGATAGCGTCAATCGAGGGCGTCGCAAACAGCGgaacacaaacagaaacacaaacacaaacacaaataataatgcgCCAACGGACACACAGAAGAGCGAGCTGCAGGCGGCCATGGAACGGAAACCGAAGGGCTGCTCGCGGGCGCAGCTATCGAAGCGTTACGAGGAGGCCATAGCCAGCTATATGAATGCCGACTGTGATCTGTGCGACTTCAGCACCAAGTACCTGTCCCAGTTGAAGGTCCACTTCCTGGAGGTGCATCAGCGCGACGCGTATCTCAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAACTGATGGATCACATCCGCAAGCACATCAATCCCAAGCTATTCACCTGTTCGATTTGCAACAAATCGCTAAATTCCCAGGATTATCTGGCCACGCACATTGAGACGGTGCACAACAAGGTCGCCCAGATTGGCAAGGTGCTGAAGTATCCGTGCCCGAAATGTGAGCGCACCTTCAGCAGCGAGAGGCGTTTGGGTAATCATTTGCTGAAGCACGACACGGATCAGTTGGAGCACAGTTGCCACATATGCCACAAGAGCTTTGCGAATGTGCACCGACTGCGTCGGCATATACAGTCGATCCATGAGGATGTGCATCCGCATGTCTGCGACATTTGTGGCAAGAAGTTCAAGTTTAAGCCATCGTTCGAGCGCCATTTGCTGGAACATCAGGGCGTCGTCGCACCAGCGATGGAGTGCTCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTCTGCGACTGCATCGATTTACGCACGATAGCACCGATACTGTCTGTCCCCATTGCTCCAAGACGTGCAGTTCGCGGACAGCGTTGCGCGCCCATGTTAAATATGCTCACAAGCTGACCACAAACCTGCAGTGCACGTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAACCTCGAGGAGCACATGGCGATACACACCGGCCTCCAGCTATACAATTGCCCCCACTGTCCCAAGGAGTGCAGGTCGCGCTCCAACATGTATGTCCACATCAAGCAGAGGCATGCGGACGAGTGGCTCAAGGCCAAAATGGCACGCTCCCATAATCCGCAGTTTAAGCCGCACGCCTAA
Protein Sequence: MICRLCLKSINANNAVYLFETNDTLAESSLLKIIAKFLQLEIMPDDNISTNICHDCCEHLEDFNNFWQLVEQKQLTLKKEFLNVDVDCVALKWTGGIDVDVNIDELPLVTDEMDEKPLDIHNLSLLGSVLDVNVDSVEVPQLHAAPKLLHNPDQLLPLHVFNPDDDDDDNDDDVDEKPIMNESSDSTPHTSSDDDDEVPLVKLKHKLKPKRKGRIVARNEQRRLTLAQELNQLLDDTDTGCDNDNDGDSVNRGRRKQRNTNRNTNTNTNNNAPTDTQKSELQAAMERKPKGCSRAQLSKRYEEAIASYMNADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDVHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHVKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00610817;
90% Identity: iTF_00553200;
80% Identity: -