Basic Information

Insect: Drosophila heteroneura
Gene Symbol: hang
Assembly: GCA_035042245.1
Location: JAWNLO010001130.1:145564-162070[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.36 23 5.6 1.0 3 23 516 537 515 537 0.93

2 18 1 66 4.1 3.2 3 22 644 663 642 663 0.89

3 18 0.00078 0.049 14.0 3.3 1 22 774 795 774 797 0.90

4 18 0.089 5.7 7.5 0.1 2 21 809 828 808 829 0.93

5 18 0.0009 0.057 13.8 0.2 2 23 977 999 976 999 0.95

6 18 0.0026 0.16 12.3 0.1 1 23 1007 1030 1007 1030 0.96

7 18 0.0002 0.013 15.9 0.2 2 23 1121 1142 1120 1142 0.97

8 18 0.00037 0.024 15.0 2.9 2 23 1237 1259 1236 1259 0.97

9 18 0.029 1.9 9.0 0.2 2 23 1268 1290 1267 1290 0.95

10 18 0.0017 0.11 12.9 0.3 1 23 1303 1326 1303 1326 0.97

11 18 0.00016 0.01 16.1 1.1 1 23 1366 1388 1366 1388 0.99

12 18 0.0025 0.16 12.4 0.9 1 23 1396 1419 1396 1419 0.96

13 18 0.088 5.6 7.5 0.4 2 19 1427 1444 1427 1445 0.94

14 18 0.002 0.13 12.7 0.3 3 23 1554 1574 1553 1574 0.98

15 18 0.0014 0.086 13.2 0.1 1 23 1609 1631 1609 1631 0.97

16 18 0.00077 0.049 14.0 0.6 2 23 1725 1747 1724 1747 0.93

17 18 0.0083 0.53 10.8 0.3 3 23 1803 1823 1803 1823 0.98

18 18 8.7e-05 0.0055 17.0 2.1 1 23 2255 2277 2255 2277 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.36	23	5.6	1.0	3	23	516	537	515	537	0.93
2	18	1	66	4.1	3.2	3	22	644	663	642	663	0.89
3	18	0.00078	0.049	14.0	3.3	1	22	774	795	774	797	0.90
4	18	0.089	5.7	7.5	0.1	2	21	809	828	808	829	0.93
5	18	0.0009	0.057	13.8	0.2	2	23	977	999	976	999	0.95
6	18	0.0026	0.16	12.3	0.1	1	23	1007	1030	1007	1030	0.96
7	18	0.0002	0.013	15.9	0.2	2	23	1121	1142	1120	1142	0.97
8	18	0.00037	0.024	15.0	2.9	2	23	1237	1259	1236	1259	0.97
9	18	0.029	1.9	9.0	0.2	2	23	1268	1290	1267	1290	0.95
10	18	0.0017	0.11	12.9	0.3	1	23	1303	1326	1303	1326	0.97
11	18	0.00016	0.01	16.1	1.1	1	23	1366	1388	1366	1388	0.99
12	18	0.0025	0.16	12.4	0.9	1	23	1396	1419	1396	1419	0.96
13	18	0.088	5.6	7.5	0.4	2	19	1427	1444	1427	1445	0.94
14	18	0.002	0.13	12.7	0.3	3	23	1554	1574	1553	1574	0.98
15	18	0.0014	0.086	13.2	0.1	1	23	1609	1631	1609	1631	0.97
16	18	0.00077	0.049	14.0	0.6	2	23	1725	1747	1724	1747	0.93
17	18	0.0083	0.53	10.8	0.3	3	23	1803	1823	1803	1823	0.98
18	18	8.7e-05	0.0055	17.0	2.1	1	23	2255	2277	2255	2277	0.99

Sequence Information

Coding Sequence: ATGTGCGACgctgccacaaaaacaacaacaacagcagcagcaacgacaacaacaactgcagcagcagtagcacaaggaacaggagcaggagctgctgGCGATACAGCGATGGAAGAACAAAATCAACGAGAGCGACAAAGCTGCTGTCGCCTATGCATTGCGCCCGCCAGTGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCGCTGGCCACTAAAATACACAACTGCGTAAATATCAAGATCACATCGGTGGATCGTCTGTCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTTAGCTCACAGTCGAAGCAGCGCCAATGGCTGGAGACGGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAATACCattgagcaacaacagcagcagcaacagcagcagcacgaatTGAAAATGGATTCAGCGACGGCTGCAGCTGAAAAGGTGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGAAAATCGTTAACAGTCTATGTGAGTCCGAGTcataagcaacagcagcaagcacagcaacaacagtcgcagcaACATTCTCAGCAACAGCATGCAACAGGGGCAAGATCAACAACGAAAACatcagcggcggcggcagcggtggcagAGTCGCAACAAACATTGCAAACCCTTTTATTGCAGGTgcccacagcagcagcagcagcagcagcgacattGGCAACGTCGtcaacacagcaacagcaacagcagcgcaagtatcaacagcagcagcaacagcaacgtggcaagcagcagcaacatcagtatcatcaacagcagcagcgacagagTCGCGTTCGTCAACCgcgacgacagcaacaagcCGCAACGGGCAAATTCAGGAGCAAGTTGTATGTGCCATTGGATATATCGGTGCCAGCACTACCAGCGCTgttgccgccaccgccgccagctgttgctgatgcagcgtcgttgccattgccgctgtcgctgccaCTTGATTTCAGCCAGAATCcgaatccaaatccaaatcccaATCCAAATCTAAATCAGAGATATACAAGTAGCGTTTTAGtgtcgcagccgcagccgccgccgctgccgctgccccCGCCAGTTGCAACAATTAGCAGCAACGAGGCTGCCATTGCCGCTGCCATTGGCTGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTACTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCGGCTGCATCGCTGCCGGCCAGCGCCGTTGCCAATGTGGCCGCCGCTGGCGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCAATCACCAAACCGACCCCGGCCCTCGCCGCCGCCTTGGAGATACAGCgtgcagcggcggcggcagcggcaaccGCTGAGGCAACGCGTGCCGCTGCCGGTGGCAATATATCGGCGCAAAAGTATCGACAGGTGGTGATGAACACGTTCATCAAATGCGAAAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCACGACAAGGTCGACTTCATACAGGAGAACAGCGAGTTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTACTTCAACACGTACAAAAACTTTATGGCGCACGTACGCAAAAAGTATCCATTGTTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTccatgccaatgccaatgcctcATCCACTTCCACTCCAGCCGCAACGACTGCtgtacaccagcagcagcagcagcagcaacagttggtgACAGCAAacgaaacagcagcaacaccaacagcaacaacatcaacggaTCGACCGGAGAAGTTGCGTGCCAAGGAGCTCCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACAAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTCCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCCGTAGATCGGCGAAGGCACTACAATAACATGGATTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCGAAACTGGAGACGCATCAGCGATTCCTCGACCATGTCTATCAGGATCATTTGGGTGGGGTGAGCAGTGATAATGCATCGTCCACGGCGACGACCAGCGGCATGGATCATTCGCCCGGGAAGCGCAGTTTGCTGGGCGCCCTTGGCATCGGCGTTGTCAGTCAATCCTCCAATGATGAGtcgcgcagcagcaacaaccacaacaacaacaataataacaacagcaacaacaacaacaacaacaatacaccTCTAACCTCGACACCTAAACTACCAACCgtagcaggagcagcaacagttgttggaggaggaggaggagcagcagcagcaaccagtgGCGGATCGACAACATCGGGCAGTCGAGATGCACCCAAATCACAGTATTTCTCACGAATGCCACAGGTCTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATATAAGTGTGTCCGTTGCGGATTGGGCTATCCGCGGATATCCTACCTGCGGGAGCACATGATCAATGTGCATGGCGTCGACAAGAATCGGCATTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTGATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgatgatggcGGCAACGGCGGCAACATTGCCAAAAAGATGAGACTCGAtgatagcagcaacaacagcagcagcatcaacatgAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTTAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAACCGCATGACGCCCAAATCGCTGACAATAACAGCGACGCCACCGCTGGAGacaacgacagcaactacaactgcagCGGGAGttgcagcatcatcatcaggaGCAGTTGCCTCAACAGCATCAGGATCAGGCTCATCATCCGGCAACTTGCCGCCAGCAATGGTCCATCAGACGGCACAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGCATCTGTCAGCGCAGATTCAGTTCGAAGAAATCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGGCGGGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACGGTCTACAGTTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACACGCCAGTgattcatcatcatcagcagctggTGGtcctgCTGAGCTGGTCGCAGACACATCATCCTCGTCGGGGACGGCGGGTGCGGCAATTCTGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAATTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTCTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcaacagcagcagcagcagcaacaacaacagcagcaacaacagctgcagctgcaacatcaTCAGCGACGCATCTTCAAGCACAAAAcgggcgatgatgatgacgaggaggaggacgatgaTCAGTTGCTGCTAATGGACGATGGTGGTGGCGGCAGCAATGATAGCAATGCTGGCAATGCCattgcatcagcagcagcggcagcagcagcagcggcagcagcagcagtcacaatAAATACGAGCACAATGAAGATACGCATTCCGGAGGTTGCATGCACCATTTGCGGTGCCCGTTTCACCGATCAGGAAATATTCACCAAGCATATACAGAAACACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGGTTGAACACCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCGCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCAATCAACGACGGCGAAGCGACAACgctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTGGGTCTGATGcccaatcagcagcaacaccaaaaacaacaacagcaacaacaacagcagcagcaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGCGAATATTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGGCGTGTCGCCGTTGCGGCGATCTACAATTTGATACCAAAGAGCAGTGGATCGAACATAAGCTGGCCGATGCGCGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAGCCACCAGCACCGGCAGCAGCCCATAAaactgcagcggcagcagcggcagcaacaacaccaacaacagcggcaacaacaacaacaattgccgccgcagcaacagttgcagctgctacatcagcagcagcagcaacggcggcGACGAAGTCagcgtcaacagcagcaaaagaacaTAAGGctaaacaacagcagcaggaggatgAGGACCTGCAGCTGGATGATGAGAAGCTagcgaagcagcagcaacaggaggaggaggaggatgataGTGATATGGATGATGGTAGCGATAGTGGcaatgatgatgaggagggCAGCACCAGtgctgacgatgatgatgatgatgacgatgatgatgaggagggCGAcggcgatgacgacgatgatgatgatgacgaagaagaagacaacGACAATGGCGAAAATGTTGTtgcgcagcagcaaatgctgcaacaacagcctcaaaatacaaacagcaacaccaacaacaacaacaacaacggcagcagcagcgcaattGAAAATGACGATGATCTCATTGAGGAGGTGATCGAGGATGATGGCATTGTCGAGCAGCTGGacgtcgatgatgatgaggaagacgatgatgatgatgacgacgatgatgatgatgatggcgaagacgatgacgatatcgatgaggatgaggacgaggacgatgagCAGCATCAGCCGAGGCGCCTCAATTTCGACTACTCGCGCACCGACAGCACCAAGCTAAATGGCAACGGTGGCAAACAGTCTGTGGCAAAATCAAAGACACAGCCACAGTTGCAGccacagttgcagcaacagttgctgacACAGCCAATGCTGGTCATGCACAGTAGTAGTAGTCGCCACGTGGATGATGGCGAGGAGGAGGTGGATGATAtggatgatgatgttgatgacgatgatgttgTGGGTGAAGCGATGACCATTGATGATATTATTGAAGAGGATGATGaagatgatgatgacgacgatgatgatgacgatgatgttgAGGAGGAcatggatgatgatgatgatgatggggaCGACGACGATGCCGATGTCAACAACACCAATATTGGCAACGGTGTTGGCCGTGTGGGTCGAGAAGatgctgatggtgatggtgatggtgatggggatggtgatggtgatggtgatgttGATGGTGGTTCATCATCATCTGAGAGCgagtcgacaacaacaacatcgcaTTCAACTGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTGCAGACACATATTAAAAGTCATTTTCTCAATGGGCCATCGGcggggagcagcagcaacagcaacaagagcaacggCGCCAGCAGGAgcaccaataacaacagcaacaacaacagtagcaacagcaacagcagtaacaaaatCAATACCAAAAAGTCCGGCTTGGATGCAacgaagacaacaacaacaacaacagttaagGCTGCTGCAGTAGCGGACGCTGTAACGGGCTTCAACTGA
Protein Sequence: MCDAATKTTTTAAATTTTTAAAVAQGTGAGAAGDTAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLETDKTKQQTLLGYLDLNRAENGNTIEQQQQQQQQQHELKMDSATAAAEKVSAANILDGIPQLKKRKSLTVYVSPSHKQQQQAQQQQSQQHSQQQHATGARSTTKTSAAAAAVAESQQTLQTLLLQVPTAAAAAAATLATSSTQQQQQQRKYQQQQQQQRGKQQQHQYHQQQQRQSRVRQPRRQQQAATGKFRSKLYVPLDISVPALPALLPPPPPAVADAASLPLPLSLPLDFSQNPNPNPNPNPNLNQRYTSSVLVSQPQPPPLPLPPPVATISSNEAAIAAAIGCGATATATAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATRAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLSHDKVDFIQENSEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANANASSTSTPAATTAVHQQQQQQQQLVTANETAATPTATTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTATTSGMDHSPGKRSLLGALGIGVVSQSSNDESRSSNNHNNNNNNNSNNNNNNNTPLTSTPKLPTVAGAATVVGGGGGAAAATSGGSTTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDDGGNGGNIAKKMRLDDSSNNSSSINMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLETTTATTTAAGVAASSSGAVASTASGSGSSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSHASDSSSSAAGGPAELVADTSSSSGTAGAAILLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQLQLQHHQRRIFKHKTGDDDDEEEDDDQLLLMDDGGGGSNDSNAGNAIASAAAAAAAAAAAAVTINTSTMKIRIPEVACTICGARFTDQEIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPINDGEATTLNNSSNNSSSSNNNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQQQQQQQQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLACRRCGDLQFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPPAPAAAHKTAAAAAAATTPTTAATTTTIAAAATVAAATSAAAATAATKSASTAAKEHKAKQQQQEDEDLQLDDEKLAKQQQQEEEEDDSDMDDGSDSGNDDEEGSTSADDDDDDDDDDEEGDGDDDDDDDDEEEDNDNGENVVAQQQMLQQQPQNTNSNTNNNNNNGSSSAIENDDDLIEEVIEDDGIVEQLDVDDDEEDDDDDDDDDDDDGEDDDDIDEDEDEDDEQHQPRRLNFDYSRTDSTKLNGNGGKQSVAKSKTQPQLQPQLQQQLLTQPMLVMHSSSSRHVDDGEEEVDDMDDDVDDDDVVGEAMTIDDIIEEDDEDDDDDDDDDDDVEEDMDDDDDDGDDDDADVNNTNIGNGVGRVGREDADGDGDGDGDGDGDGDVDGGSSSSESESTTTTSHSTAAHGAAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPSAGSSSNSNKSNGASRSTNNNSNNNSSNSNSSNKINTKKSGLDATKTTTTTTVKAAAVADAVTGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596083;
90% Identity: iTF_00486003;
80% Identity: -