Basic Information

Insect: Drosophila heteroneura
Gene Symbol: Hr39
Assembly: GCA_035042245.1
Location: JAWNLO010000276.1:520008-523466[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 2 1.7e+04 -6.4 18.9 40 204 38 219 22 226 0.45

2 3 2 1.7e+04 -11.4 31.2 27 138 211 335 199 378 0.37

3 3 2.2e-99 1.8e-95 320.6 19.8 1 408 515 916 515 916 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	2	1.7e+04	-6.4	18.9	40	204	38	219	22	226	0.45
2	3	2	1.7e+04	-11.4	31.2	27	138	211	335	199	378	0.37
3	3	2.2e-99	1.8e-95	320.6	19.8	1	408	515	916	515	916	0.85

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGTTAACATGTCGACGGCGACAGTGACGCCagcgtcgcagcagcagcagcaacagcagcagcaacagcagcagcagcagcgccacaaTGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcacagcGGCAGCCTGTGCATACCCCTCGGCGGCAATGGGGATGAGTCCGATTCGGATGCGGAACTGGCCAACATTGAGAATCTGAAGGTGCGACGACGTGCGTCAGACAAGAATGGTCCGCGTCCCATGTCTTGGGAGGGTGAGCTGAGTGAGAACGAAACGAATGGCGGCGCCGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcaccagcagcagcagtagtgcCACAACAATGGCCAGCAGACAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGAACATAGCCGGCgagatgcaacagcaacagcaacagcagcagcagcagcagcaacaacagcagcagcagcaacaacaacagcagcagcaacaacaacaacagcagcagcaacaacaacagcagcagcagcagcaacaacttcagctgcaacaacaacaacaacaattgctgccaCTGAAGCAACAGAGCTTTGCACCGAACAACAAACTGAAATTGGCGCCGACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTATACGCCCTCGCTGAGCAGGAACAACAGCGATGCGTCGCACAGTAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCCATTCAGGCGCGTCATGCGCCACTCGCTGGCGTCGCTGCCTTGTTCACGGGCAATGCAAATGGCGGTGCACTGCATCATCACAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTAAGCATGGACGCGGGTGGTGCATCATTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGCCAGCAGCTGATCAATTCACCGTGTCCGATTTGTGGGGATAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgaggcgGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGTGGCGGTCGCTCCACCTATCAGTGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGCCCCGATCAGGCGGCAGCCgctgcagccgccgccgccgttgtcaatcaacagcagcagcagcagcatcagcaccagcatcagcagcagcatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacatcagcagcagcagcaacatggtCCACTCAATGGCTTTGGTGGTGGCGGTTCCAATTCGCTGCCAGCTAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAATCGGAGCAGCTAAATCATCATACGTCATCATCAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACGGGTGGCTCATCGTCGAGCAGCACGGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCGCATCCAACGGCGAGAACGCCAATCCCGATCTGATTGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGACACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGTTGAATCTGACCGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGCTTGCAGGCCTACACGCTGGCCCATTACCCCGAGACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTgcagattttaatttgctaatGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPVNMSTATVTPASQQQQQQQQQQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLCIPLGGNGDESDSDAELANIENLKVRRRASDKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSTSSSSSATTMASRQVNAMLQPIKTELENIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQQQQLLPLKQQSFAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPLAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGASLDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQQQHQHQHQQQHQQHQQQRLQQHQQQQQQQQHQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQSEQLNHHTSSSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSSTGGSSSAGQHTGNAQQMTNPLLASAGLASNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00518486;