Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018404.1:5163218-5169769[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0007 0.067 14.1 1.5 1 23 145 167 145 167 0.97

2 14 4.1 3.9e+02 2.3 0.8 1 23 173 196 173 196 0.89

3 14 0.00043 0.041 14.8 0.5 1 23 381 403 381 403 0.98

4 14 7 6.7e+02 1.5 5.6 1 23 409 432 409 432 0.93

5 14 1.7 1.6e+02 3.5 0.1 1 23 447 470 447 470 0.92

6 14 0.0044 0.42 11.6 2.1 5 23 774 792 771 792 0.92

7 14 0.05 4.8 8.3 1.4 1 23 798 821 798 821 0.98

8 14 0.00097 0.093 13.7 0.7 1 23 901 924 901 924 0.97

9 14 0.0041 0.39 11.7 0.2 1 23 1185 1208 1185 1208 0.92

10 14 0.011 1 10.4 2.7 1 23 1220 1242 1220 1242 0.98

11 14 0.0065 0.62 11.1 0.6 1 23 1247 1270 1247 1270 0.93

12 14 0.0021 0.2 12.6 3.8 1 23 1276 1301 1276 1301 0.95

13 14 0.0041 0.39 11.7 4.1 1 23 1306 1328 1306 1328 0.97

14 14 0.0011 0.1 13.5 0.8 1 23 1334 1357 1334 1358 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0007	0.067	14.1	1.5	1	23	145	167	145	167	0.97
2	14	4.1	3.9e+02	2.3	0.8	1	23	173	196	173	196	0.89
3	14	0.00043	0.041	14.8	0.5	1	23	381	403	381	403	0.98
4	14	7	6.7e+02	1.5	5.6	1	23	409	432	409	432	0.93
5	14	1.7	1.6e+02	3.5	0.1	1	23	447	470	447	470	0.92
6	14	0.0044	0.42	11.6	2.1	5	23	774	792	771	792	0.92
7	14	0.05	4.8	8.3	1.4	1	23	798	821	798	821	0.98
8	14	0.00097	0.093	13.7	0.7	1	23	901	924	901	924	0.97
9	14	0.0041	0.39	11.7	0.2	1	23	1185	1208	1185	1208	0.92
10	14	0.011	1	10.4	2.7	1	23	1220	1242	1220	1242	0.98
11	14	0.0065	0.62	11.1	0.6	1	23	1247	1270	1247	1270	0.93
12	14	0.0021	0.2	12.6	3.8	1	23	1276	1301	1276	1301	0.95
13	14	0.0041	0.39	11.7	4.1	1	23	1306	1328	1306	1328	0.97
14	14	0.0011	0.1	13.5	0.8	1	23	1334	1357	1334	1358	0.95

Sequence Information

Coding Sequence: ATGGCATCAAACAATAGATTGAAAACGGGCTCAGGATCATCCGAAATAAACTACAAGTTTACATGTCGCTGCTGTCTGAAATCCGATGCGGAGTTCCTCAAGCTGGACACGCTGTCGGTGGCGCGCAATCTGGATCCAAGCGAATCCGATAAAATACCCCTTCTGCGTTGTTTGCTGTTCTGCATACGCGCGGAAAATTCGCCGGAGCTGCCGCAATACATATGCGTTGAGTGCAGCAAGAGCTTGCAAATAGCCTACTATTTCTTGCAAAATGCACTGCGCGCACACGAAATACTCTGCCGCAAACTGTGTCCGGGAAAGTCGCGTCCTACGCTGGCACAGCGCTTCAATGGTTCCATCAAACAGCCAGagGTGGCGTCGCGGCAGGCGGGTGCGGGCGACGACAAGACGAAGCCACATAAGGCATTTCGGCACGAGTGCAAACTCTGCGGCTTTGTCGTCTATAATCGGATGGAGCTAAAGCAGCACATACGTCAGCACGTTGATGGGAGCTCCTACAGCTGCAAGGTGTGCAGCTTCGTTACCCTGAAGCAGCGTCTCCTGCAAGAGCACTACAGTGCGACCCATGGCATGTCCGGCAATCAGGCGGACGAGCAAGGTAAACCCAAATCATTCTACAGTGCGGCCCCATCGACTTCATCCGCGTCCGCTGCGGCTGCCAAGGAGGAAGTTAAAGTGTGCACCCTGGAGGACATGGAGCTGCTGATTCCCACTGTTCTCACGCCCGGGGACTACATGCAACCGTCCATCGACGAAGAGCAGCTGCGCGACATCGAACAGCAATTGGCCGCCAGCATGGGGGAGCCCGTTGTCGGTGGCGAGACTTTGGCCTCCAACCTGACACAAATGGAGGGCAACAATATGAGCATTGGCACCGAGTATGTCGTGATGCCCGATGGAACCTTGCAGATCAACGGAGGCGGTGTGGTCATAGAATACATCGATGATAGCAGGCCAAATACCCACCCCACTGGGAACTTAAGCCTGCAAAATCTCCTTGGCAGCAGTCCCGAAAACGAGCCCATGGACATCGACGTCAGTGAGCTGATTGTGGAGGATACGGTGCCGCAGATAAAAGTCAAGCCAAAACCAATACCCATTGGATCTGCTCCCCTCAAGTACAAGTGCAAAGCCTGTCCCAAAGCATTTGTCACCATGGCGCGTCTGAAATCTCACCAGTTGAGCCACAGCCATTTGCCCAAGTTCTACTGCGATCAGTGCCCCTTCTATTCGCTGCGCTCTTCCGATCTCTGCCACCACTACAAGATAAAGCATCTCAAGAACGAACAGAACGGAAAGGTGGCCGCCGACGCAACCTATGCCTGCGACACGTGCCTTTTCGAAGCGAGGACCGCCACCCAGCTAGCGGTGCACATAACTGAAAAGCACAAGACTAAACCCTCGGATATAGATCTGCGTCCCACTTGGCAAAGTAGTTTGTCCGCCTCCTGTGGCGGCGTCGGCTCGGCTAGTACCAGTGGCCAGGAGCAGGGCAGTCAGCCACAGCAACCCGAAATTCCACTGGGCATTCAATATCCGTCTGCAGcgctggcggcggcggtgaCAGTTGAAAATCAGCCATtgcatcagcatcaacagcaacagcagcagcagccacaggagcaacagcagcagctcctgccAGCGATAGCAACCCAAACATCCACGATAACGCAGTCGGGCGAAATCAATGTGGTGGTAGATGCCACACCTTTGTTCTATGCGACGCCAACGACAGGgcctggcactggcactgggactgTGACTGGGGCAGAGTTAGTTGGCCAGGGACAGGGAGCTCCGGGTACAATATCCACCGAAGCAATGGCCAACGGAGACGGGCTGAACATCGGCAACACATATGACATCTTTCCAGAAATCTCAACGAGCAGTCTGGCAGTGACTCAGCCCGTGCCGGCATTGCCAACGACAACGTCGGCGAACGTCTCGATGTTTGGGGATATGCAGGATTTTATAGACAACACAGATGTGGCCGCCATATGCACCATACCCGCCGATGATATGCCGGTGGTGGATGGTGACGATATTGTAATTGATAATAACAACATCAGCTTGGACTTTGATGCTGAGAATCTGTTTGAGGACTTTGAGGATGACGAAGAGGCCGTtggcgaggaggaggaggaggacgacgaagacgaagacgcCGAGAATGAGGATGAAAATGACAACAATGACGCGGCCACCGATCAGAATCTGCTGCTAACAAGTGACGACGACGATGTGGATGACTTTGACGACGAGCAATCGAAGCATCTGCAAAAACCCTACTGCATATTCTGCAACAAAAAGTTTACGAGCCAATACAAGTTCGAGAATCACATGTTTGTGCACCGAGGTCTGGCCCCCTACCGCTGTGAGCTCTGCACCAATCTGTACAACATGAAGCGTCTCCTCATCAGGCACTACAAGACCGTACACAGGCGCATGCCCACACGGGACATGGTCCAGGCGAAGGGCGACAAAGTATTGGTGGCCCGTACCAATATCGAGACAATTCAACTGGATCAGGACAGGAAGCCCATGCTGATGTGTGCCAAGTGTCCGTTCGAGTGTGAACTGGATGCGGAAATGCGAAAGCATTTGAATGCGCACCACGGCATCAACGATGGTGTGTCCGTGCATGCCAACGAGGTGTTCATTATCCGCAAACTACCCTTTGAGTGTCCGCGATGCATTCGCTCATTTGCGGCCAAGAGCACACTGACCCGCCATCTGCAGCGTAGCCATTTGGTGGACACGATAATTGAGATGCAATCCAACCAAATAACAACAAACTCGGCAGCCACAACCACCAGTACCACGTGCACAGCAACCACCTCATTGCCGGCGAACACGGCTGACGATAATGGGAATAAAGGGCAGCAGCTCGAGACAGATCGGCCGGCAACGTCGGAGACGGTTGGCTATGGCGATGGGGAATGCGAGGTAGCTGTCAAACCTGAAGGCGCAACGACAACAGCAGCCGGAGCTGAAAAAGAAGAGCCAACGACTAGTTCagccgcatccgcatccgcatcatcatcatccataATATCAACCATAAAAGCAGACCCAGCATCAGAAAGAATTCCTAATCCCCCCGACGAATCGTCAGAGCCACGAGCCATGAACAGCATAGATTATATTCCAGTCAAGGGCGAGACAGCATCTCCGGGCGCAAAAGCATCGGCACATACCGCCACAATAGCGTCATCGTCAtccacaccaatgccatttgATTTTGACTTTGATTTTATTGGGGATGGAGGAAAAACCAGGCTCACGCCTACGCCCACCACACACAGTACGCCCAACAAAACTAGCAACAAACAAATCGTCAGCACCACAGAAGCAACACCACAGTTCCCTTGCACTACCAATCCGAGCACGAGCACCACCAACATTAGCACCAGCACCAATGCCTTTGCACCGAGCGCCCTACTCAACGGCAGCGACAAACTGTTGACTGCCGCAATGGAGCCATCGCCCATTAAGGGCCTACGTCCGCGCCTCCCCCGTACCCCCAACTACGCGTGCAAGCTCTGCAAAAAGAGCTTCGATGAGCTGGGAAAGCTGGTAAAGCATGAGATGGACGCGCATACCGTTGGCCAATCGACACGCTTGGGCTATGAGCACCGATGTGGCACCTGCGGCACAACGTATCGCACAGTAGCCCTCCTCAAGTTCCACATGAAGCGGCACCAGACCCGCAAGTTTACGTGCAAGCTGTGTGCAAAGGAATTTGTATTCAAAACTGAATTGGACAGGCACGTGCTGGCCAAACATGCCACCGAGAAGTCGTTCCGGTGTTCTCTGGATGGCTGTCGCAAGATGTTCGCCTTCAAGCATCATTTGGTGCGGCATCAGAATGCATCCCATCTGAAGTTGCGCCATGTGTGCGCGATATGCCAGAAAGAGGTGAAGACCAGCCTGCATCTGAGGCACCACATGACCGTGCACAGAGGCATGACGGCCTACAAGTGCCCCAAATGTGACCGCACATATTTACGTCGCGGAGCCCTTCGTGTCCATGCGCTGTCCGTCCATCATGTGCAGCTTACGGAGACAGAACTGGCCGAAGTCTTTCGCAACAATGTGGGCTATACCAATCCGCACGACATGAAGGTATTCACACGCAACGGGCAATTGGTGCGCCGCAAGGAGCTGGAGGCCGGAAAGGAAAGGGAAATGCAGATGGGCGACGAATCATCCACGGCAGTGGCGAATATATCCAAATAA
Protein Sequence: MASNNRLKTGSGSSEINYKFTCRCCLKSDAEFLKLDTLSVARNLDPSESDKIPLLRCLLFCIRAENSPELPQYICVECSKSLQIAYYFLQNALRAHEILCRKLCPGKSRPTLAQRFNGSIKQPEVASRQAGAGDDKTKPHKAFRHECKLCGFVVYNRMELKQHIRQHVDGSSYSCKVCSFVTLKQRLLQEHYSATHGMSGNQADEQGKPKSFYSAAPSTSSASAAAAKEEVKVCTLEDMELLIPTVLTPGDYMQPSIDEEQLRDIEQQLAASMGEPVVGGETLASNLTQMEGNNMSIGTEYVVMPDGTLQINGGGVVIEYIDDSRPNTHPTGNLSLQNLLGSSPENEPMDIDVSELIVEDTVPQIKVKPKPIPIGSAPLKYKCKACPKAFVTMARLKSHQLSHSHLPKFYCDQCPFYSLRSSDLCHHYKIKHLKNEQNGKVAADATYACDTCLFEARTATQLAVHITEKHKTKPSDIDLRPTWQSSLSASCGGVGSASTSGQEQGSQPQQPEIPLGIQYPSAALAAAVTVENQPLHQHQQQQQQQPQEQQQQLLPAIATQTSTITQSGEINVVVDATPLFYATPTTGPGTGTGTVTGAELVGQGQGAPGTISTEAMANGDGLNIGNTYDIFPEISTSSLAVTQPVPALPTTTSANVSMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDDEEAVGEEEEEDDEDEDAENEDENDNNDAATDQNLLLTSDDDDVDDFDDEQSKHLQKPYCIFCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHRRMPTRDMVQAKGDKVLVARTNIETIQLDQDRKPMLMCAKCPFECELDAEMRKHLNAHHGINDGVSVHANEVFIIRKLPFECPRCIRSFAAKSTLTRHLQRSHLVDTIIEMQSNQITTNSAATTTSTTCTATTSLPANTADDNGNKGQQLETDRPATSETVGYGDGECEVAVKPEGATTTAAGAEKEEPTTSSAASASASSSSIISTIKADPASERIPNPPDESSEPRAMNSIDYIPVKGETASPGAKASAHTATIASSSSTPMPFDFDFDFIGDGGKTRLTPTPTTHSTPNKTSNKQIVSTTEATPQFPCTTNPSTSTTNISTSTNAFAPSALLNGSDKLLTAAMEPSPIKGLRPRLPRTPNYACKLCKKSFDELGKLVKHEMDAHTVGQSTRLGYEHRCGTCGTTYRTVALLKFHMKRHQTRKFTCKLCAKEFVFKTELDRHVLAKHATEKSFRCSLDGCRKMFAFKHHLVRHQNASHLKLRHVCAICQKEVKTSLHLRHHMTVHRGMTAYKCPKCDRTYLRRGALRVHALSVHHVQLTETELAEVFRNNVGYTNPHDMKVFTRNGQLVRRKELEAGKEREMQMGDESSTAVANISK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575090;
90% Identity: iTF_00484653;
80% Identity: -