Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018404.1:13604772-13608440[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6 5.8e+02 1.7 0.0 1 23 363 388 363 388 0.92

2 16 0.036 3.5 8.7 2.2 2 23 399 420 399 420 0.93

3 16 3.7 3.5e+02 2.4 0.5 3 23 461 482 460 482 0.92

4 16 0.039 3.7 8.6 0.3 3 23 490 510 488 510 0.90

5 16 0.0016 0.15 13.0 0.2 1 23 518 541 518 541 0.98

6 16 0.00074 0.071 14.0 0.2 2 23 546 567 545 567 0.97

7 16 2.8e-05 0.0027 18.5 1.0 1 23 615 639 615 639 0.92

8 16 0.14 14 6.8 1.8 1 21 644 664 644 665 0.94

9 16 0.15 14 6.8 0.4 1 23 684 709 684 709 0.95

10 16 0.8 76 4.5 1.9 2 23 727 749 726 749 0.94

11 16 0.062 5.9 8.0 0.3 3 23 756 777 755 777 0.90

12 16 0.075 7.2 7.7 0.2 2 23 781 803 780 803 0.95

13 16 5.7e-05 0.0055 17.5 2.0 1 23 809 831 809 831 0.98

14 16 0.0046 0.44 11.5 1.5 1 23 835 858 835 858 0.93

15 16 3.4e-05 0.0032 18.2 2.4 1 23 864 887 864 887 0.97

16 16 1.3e-05 0.0012 19.6 0.6 5 23 900 919 891 919 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6	5.8e+02	1.7	0.0	1	23	363	388	363	388	0.92
2	16	0.036	3.5	8.7	2.2	2	23	399	420	399	420	0.93
3	16	3.7	3.5e+02	2.4	0.5	3	23	461	482	460	482	0.92
4	16	0.039	3.7	8.6	0.3	3	23	490	510	488	510	0.90
5	16	0.0016	0.15	13.0	0.2	1	23	518	541	518	541	0.98
6	16	0.00074	0.071	14.0	0.2	2	23	546	567	545	567	0.97
7	16	2.8e-05	0.0027	18.5	1.0	1	23	615	639	615	639	0.92
8	16	0.14	14	6.8	1.8	1	21	644	664	644	665	0.94
9	16	0.15	14	6.8	0.4	1	23	684	709	684	709	0.95
10	16	0.8	76	4.5	1.9	2	23	727	749	726	749	0.94
11	16	0.062	5.9	8.0	0.3	3	23	756	777	755	777	0.90
12	16	0.075	7.2	7.7	0.2	2	23	781	803	780	803	0.95
13	16	5.7e-05	0.0055	17.5	2.0	1	23	809	831	809	831	0.98
14	16	0.0046	0.44	11.5	1.5	1	23	835	858	835	858	0.93
15	16	3.4e-05	0.0032	18.2	2.4	1	23	864	887	864	887	0.97
16	16	1.3e-05	0.0012	19.6	0.6	5	23	900	919	891	919	0.86

Sequence Information

Coding Sequence: ATGTCCGAAAACCCAAAAATAAACCGCAGCGCTCCTAGCTGCCTGCATTGTGGCGCATTCGGTGCGAAATTGAAGTATCAGGATATATTTGATGAATTTGGTCTGGAACTAGGACTCCAACAGCTGCTGGCGAAGCACTTCGACTTAGATGCGACGCCCAAAGCAAAGAAACAACAGTTCCTCTGCGAGGAGTGCGTGAATGTTTTGATCCGATTATTTGACATTGACGAGCTCCAGAAAGAACAGGATGCTgcaattgccaaaaaaaagagcGCTGCACAGGCTGCTCCTGCAGCAAAGAGTGCATCCAAGACGCCTCCTACCCCAAAGAGTGCGTCCAAGGTGCCTCCAAATGCTGCAAAGCCCGCTAGGAAGGCCACACCGCCGGAGCCCCAAACTAAAGTGGAAAAGGTGGAACAGCCGGACCCAAAACCCAGCCGACgtataattaaaaatgtatcaGCCCCACTGCCATCTGCTGCCGTCGTGGCACCCGTAGCAGCCGTAGTTGATAAAGTCAAGGCACCATCCAAAACAACCGTGAAGGTGGTTAAGCATGCTCCACAGGACGCAGACCACGAGCAGATTAGTGCCCTCATTCTTAATATTCTTAACGATGATGAACCGGGTGAGGAAGATGAGGCAGACACAGGTCTTCCCAAATCTCCCCAAACAACAATTGCTGTGACAGAGAACGAAGCGATGGATGTTGAGGAAAAGGAAGAACAAGAACTAGATGGATTGCATATAATATACGAGCATGAGGATATTTTACTTGAAGAGGAGGTCAATACCAAGCCAGACGTCCATCCATCTAGAATCAAAAGGCAGAAAACGGAAAGCCAGAGCGAAGCAGACAACGAGGAGGGCGAGGCCAGCAATATCGTCCTTTTTAACTTCGTCGAGATCAAAGAGAAGGATGATATTGACGACCTTTATGAATATTTGGCCACGGTGGTGAGGACCAGCTTTGAAAAGCTAAAGTTCGACTGGAGCACTGTGTGCCAACTTTGCACATTTAAGTCCGCTAGCTACGAGATCCTGCTGGAGCATATGCTGAGGGTGCACAAGTCCCGGGCGGATGTCTTTCGCTGCCCAATCGAGGGCTGCAGCTTGGAGATAAAAGGACGCAAACTTCTGGCCATGCATTTGGTGGTTCTGCACGCGCCTGTGGCTGATATTTCCATTTACGGCAGCTGTCCGGAATGCAAGATGACATTCTCAAATATCTTACAGTACAATAAACATTCATGTGCGCACATCATCAAGAAGAAACGAGGCATTCGATTGTTTTGCGAAATGTGCGCTCTAGAGTTTCCCTCCTGGAAGCGCTTCAATTTTCACAATCAATTCCATTTGGAGAAGCACCGACCCCGTGCGTGCTTTGTCTGTGGCTATGAGAACACCAACATCGACGAGCTCTTCCAGCATTTGCACTATTCCCATGAGCCAGAAGGCACTCTCTTCTGTGATCTTTGCGATCGCACGTTCCGAGATGCCGCAGTCTTCCTGGAGCACAACACGTCGCATGCGACTGTGGGCAGCGCCACGTACATCTGCGGCGAGTGCCTGGCCCCCTTCGAGACTCGTGGCAAACTGAATAGCCACACGAGAACAATGCATGGCAACGTCATCAGCTGTGAGCTCTGCTCCCGCGAGTTTGCCTCTGAGGGCACCTACAACGTCCACATGAAGAGCCATTTGATTATCGAACGGGATGTTCATGTCTGCGGCACTTGTGGCCAACTGAGTGAGAATCAGGAGAAAATGGACACCCACTTGGGGACCGAGGGCTCTACCTGCTTTGGGGCGGAGAGTTACGTGGAACTGCTACGCGATGCCTATGTCTGTGAATACTGCACCACGTACTTTAAGCAGAAGTCCGACTTACAGTCCCATCGCGAGACCGGTGTGCACAATGATGGCGTATTTCGGTGCCAGCCTTGCGAAAAGAATTTTACCGACATGAAATTATATCGACACCATTGGCGCAACTATCAACAGTTGCGAGTAGATGTTGCACATCGGAAGCTGGACATTTGCACCTTCTTCATGTGCGACCAAAAGGGCTGCTTGGCGGCATATGCGAACTGGAACTCATTATATACGCACAAGCGACGCACTCACGATGAGGCCAAAGAGCAACAGGAGAAATCGGCCAAGCCGCTGCAGGAATGGCAATGCCAATTCTGTCTTAAGCTATGCCGCTCGAAAATGTCCTTATCCGTCCATGTCGCCCGGAGCCACAATAATGACAATGTGGCCTGTTCAGTGTGCAACTCCTCGTACAAGAGCAAGGAAGCCCTGGACAAACACTTTGCTTACTGGCACGAGCCCGTCGAGTGTCCGCAGTGCTTCAAGATAGTCAAGAACACGCGCAACTATGACACCCACGTGAATGTGGTGCattcaaacaaaaagcgcTACACCTGCAGTGTATGCGAGAAAGGCTTCTACCACAAGAGCGAGATGGAGGCTCACAAAAGGCTCCACTCCCAGTCGTACAGTTGCGATCAGTGCAACTTCACCACCAGGAACAAGAAGTCCCTGTCTGTTCATACCCTGGGCCAGCACTTTAAGCGCTTCGCCTTCGAATGCAAGACGTGCGACAAACACTTTGGTCGACGCCAGGGACTGACCAACCACATACAACGTGTGCACGCCTCCAAGCATGTGTGCCGTAACTACATTGATAATGGCTGCGGGCGTTCTTTTGCCACCAGTTCCCAGCTGAACGTGCATTTGCGGAAGGTTCACAACTCCTCTATAGCAGCCGACGATGTGCTCGAAGAGGAGGAGTATGCCATCGCCAGACCGTCGGTAGCGAAGAAACGTTGCTTTGGAATCTTGAAAGATACCAAAGCTGACCTTATAGACGATTCTGAAGTTGATTTGGACACAATGAATGACTCTGTCTATACCGTTGTACAGAAGAATGAGAAGGAGGGGGAAGAGGAGGAGATGGAGgtggagcagaagcaggaggatGATGATGAATGTGAGGTGGAATTTGCCGAGGATGAGGCAGAGGaggaaccgaaaccgaaaccgatcCCTGGCTCAGGCAGAAAACATGGAAGAAAACACCGTTCGGATGATTAG
Protein Sequence: MSENPKINRSAPSCLHCGAFGAKLKYQDIFDEFGLELGLQQLLAKHFDLDATPKAKKQQFLCEECVNVLIRLFDIDELQKEQDAAIAKKKSAAQAAPAAKSASKTPPTPKSASKVPPNAAKPARKATPPEPQTKVEKVEQPDPKPSRRIIKNVSAPLPSAAVVAPVAAVVDKVKAPSKTTVKVVKHAPQDADHEQISALILNILNDDEPGEEDEADTGLPKSPQTTIAVTENEAMDVEEKEEQELDGLHIIYEHEDILLEEEVNTKPDVHPSRIKRQKTESQSEADNEEGEASNIVLFNFVEIKEKDDIDDLYEYLATVVRTSFEKLKFDWSTVCQLCTFKSASYEILLEHMLRVHKSRADVFRCPIEGCSLEIKGRKLLAMHLVVLHAPVADISIYGSCPECKMTFSNILQYNKHSCAHIIKKKRGIRLFCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCGYENTNIDELFQHLHYSHEPEGTLFCDLCDRTFRDAAVFLEHNTSHATVGSATYICGECLAPFETRGKLNSHTRTMHGNVISCELCSREFASEGTYNVHMKSHLIIERDVHVCGTCGQLSENQEKMDTHLGTEGSTCFGAESYVELLRDAYVCEYCTTYFKQKSDLQSHRETGVHNDGVFRCQPCEKNFTDMKLYRHHWRNYQQLRVDVAHRKLDICTFFMCDQKGCLAAYANWNSLYTHKRRTHDEAKEQQEKSAKPLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVACSVCNSSYKSKEALDKHFAYWHEPVECPQCFKIVKNTRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCDQCNFTTRNKKSLSVHTLGQHFKRFAFECKTCDKHFGRRQGLTNHIQRVHASKHVCRNYIDNGCGRSFATSSQLNVHLRKVHNSSIAADDVLEEEEYAIARPSVAKKRCFGILKDTKADLIDDSEVDLDTMNDSVYTVVQKNEKEGEEEEMEVEQKQEDDDECEVEFAEDEAEEEPKPKPIPGSGRKHGRKHRSDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580943;
90% Identity: iTF_00517935;
80% Identity: -