Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018404.1:13609787-13613458[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 6 5.8e+02 1.7 0.0 1 23 365 390 365 390 0.92

2 16 0.036 3.5 8.7 2.2 2 23 401 422 401 422 0.93

3 16 3.7 3.5e+02 2.4 0.5 3 23 463 484 462 484 0.92

4 16 0.039 3.7 8.6 0.3 3 23 492 512 490 512 0.90

5 16 0.0016 0.15 13.0 0.2 1 23 520 543 520 543 0.98

6 16 0.00074 0.071 14.0 0.2 2 23 548 569 547 569 0.97

7 16 2.8e-05 0.0027 18.5 1.0 1 23 617 641 617 641 0.92

8 16 0.14 14 6.8 1.8 1 21 646 666 646 667 0.94

9 16 0.15 14 6.8 0.4 1 23 686 711 686 711 0.95

10 16 0.8 76 4.5 1.9 2 23 729 751 728 751 0.94

11 16 0.033 3.1 8.9 0.2 2 23 757 779 756 779 0.90

12 16 0.075 7.2 7.7 0.2 2 23 783 805 782 805 0.95

13 16 5.8e-05 0.0055 17.5 2.0 1 23 811 833 811 833 0.98

14 16 0.0046 0.44 11.5 1.5 1 23 837 860 837 860 0.93

15 16 3.4e-05 0.0033 18.2 2.4 1 23 866 889 866 889 0.97

16 16 1.3e-05 0.0012 19.6 0.6 5 23 902 921 893 921 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	6	5.8e+02	1.7	0.0	1	23	365	390	365	390	0.92
2	16	0.036	3.5	8.7	2.2	2	23	401	422	401	422	0.93
3	16	3.7	3.5e+02	2.4	0.5	3	23	463	484	462	484	0.92
4	16	0.039	3.7	8.6	0.3	3	23	492	512	490	512	0.90
5	16	0.0016	0.15	13.0	0.2	1	23	520	543	520	543	0.98
6	16	0.00074	0.071	14.0	0.2	2	23	548	569	547	569	0.97
7	16	2.8e-05	0.0027	18.5	1.0	1	23	617	641	617	641	0.92
8	16	0.14	14	6.8	1.8	1	21	646	666	646	667	0.94
9	16	0.15	14	6.8	0.4	1	23	686	711	686	711	0.95
10	16	0.8	76	4.5	1.9	2	23	729	751	728	751	0.94
11	16	0.033	3.1	8.9	0.2	2	23	757	779	756	779	0.90
12	16	0.075	7.2	7.7	0.2	2	23	783	805	782	805	0.95
13	16	5.8e-05	0.0055	17.5	2.0	1	23	811	833	811	833	0.98
14	16	0.0046	0.44	11.5	1.5	1	23	837	860	837	860	0.93
15	16	3.4e-05	0.0033	18.2	2.4	1	23	866	889	866	889	0.97
16	16	1.3e-05	0.0012	19.6	0.6	5	23	902	921	893	921	0.86

Sequence Information

Coding Sequence: ATGTCCGAAAACCCAAAAATAAACCGCAGCGCTCCTAGCTGCCTGCATTGTGGCGCATTCGGTGCGAAATTGAAGTATCAGGATATATTTGATGAATTTGGTCTGGAACTGGGACTCCAACAGCTGCTGGCGAAGCACTTCGACTTAGATGCGACGCCCAAAGCAAAGAAACAACAGTTCCTCTGCGAGGAGTGCGTGAATGTTTTGATCCGATTATTTGACATTGACGAGCTCCAGAAAGAACAGGATGCTgcaattgccaaaaaaaagagcGCTGCACAGGCTGCTCCTGCAGCAAAGAGTGCATCCAAGACGCCTCCTACCCCAAAGAGTGCGTCCAAGGTGCCTCCAAATGCTGCAAAGCCCGCTAGGAAGGCCACACCGCCGGAGCCCCAAACTAAAGTGGAAAAGGTGGAACAGCCGGACCCAAAACCCAGCCGACgtataattaaaaatgtatcaGCCCCACTGCCATCTGCTGCCGTCGTGGCACCCGTAGCAGCCGTAGTTGATAAAGTCAAGGCACCATCCAAAACAACCGTGAAGGTGGTTAAGCATGCTCCACAGGACGCAGACCACGAGCAGATTAGTGCCCTCATTCTTAATATTCTTAACGATGATGAACCGAGTGAGGAAGATGAGGCAGATACAGGTCTTCCCAAATCTCCCCAAACAACAATTGCTGTGACAGAGAACGAAGCGATGGATGTTGAGGTTGAGGAAAAGGAAGAACAAGAACTAGATGGATTGCATATAATATACGAGCATGAGGATATTTTACTTGAAGAGGAGGTCAATACCAAGCCAGACGTCCATCCATCTAGAATCAAAAGGCAGAAAACGGAAAGCCAGAGCGAAGCAGACAACGAGGAGGGCGAGGCCAGCAATATCGTCCTTTTTAACTTCGTCGAGATCAAAGAGAAGGATGATATTGACGACCTTTATGAATATTTGGCCACGGTGGTGAGGACCAGCTTTGAAAAGCTAAAGTTCGACTGGAGCACTGTGTGCCAACTTTGCACATTTAAGTCCGCTAGCTACGAGATCCTGCTGGAGCATATGCTGAGGGTGCACAAGTCCCGGGCGGATGTCTTTCGCTGCCCAATCGAGGGCTGCAGCTTGGAGATAAAAGGACGCAAACTTCTGGCCATGCATTTGGTGGTTCTGCACGCGCCTGTGGCTGATATTTCCATTTACGGCAGCTGTCCGGAATGCAAGATGACATTCTCAAATATCTTACAGTACAATAAACATTCATGTGCGCACATCATCAAGAAGAAACGAGGCATTCGATTGTTTTGCGAAATGTGCGCTCTAGAGTTTCCCTCCTGGAAGCGCTTCAATTTTCACAATCAATTCCATTTGGAGAAGCACCGACCCCGTGCGTGCTTTGTCTGTGGCTATGAGAACACCAACATCGACGAGCTCTTCCAGCATTTGCACTATTCCCATGAGCCAGAAGGCACTCTCTTCTGTGATCTTTGCGATCGCACGTTCCGAGATGCCGCAGTCTTCCTGGAGCACAACACGTCGCATGCGACTGTGGGCAGCGCCACGTACATCTGCGGCGAGTGCCTGGCCCCCTTCGAGACTCGTGGCAAACTGAATAGCCACACGAGAACAATGCATGGCAACGTCATCAGCTGTGAGCTCTGCTCCCGCGAGTTTGCCTCTGAGGGCACCTACAACGTCCACATGAAGAGCCATTTGATTATCGAACGGGATGTTCATGTCTGCGGCACTTGTGGCCAACTGAGTGAGAATCAGGAGAAAATGGACACCCACTTGGGGACCGAGGGCTCTACCTGCTTTGGGGCGGAGAGTTACGTGGAACTGCTACGCGATGCCTATGTCTGTGAATACTGCACCACGTACTTTAAGCAGAAGTCCGACTTACAGTCCCATCGCGAGACCGGTGTGCACAATGATGGCGTATTTCGGTGCCAGCCTTGCGAAAAGAATTTTACCGACATGAAATTATATCGACACCATTGGCGCAACTATCAACAGTTGCGAGTAGATGTTGCACATCGGAAGCTGGACATTTGCACCTTCTTCATGTGCGACCAAAAGGGCTGCTTGGCGGCATATGCGAACTGGAACTCATTATATACGCACAAACGACGCACTCACGATGAGGCCAAAGAGCACCAGGAGAAATCGGCCAAGCCGCTGCAGGAATGGCAATGCCAATTCTGTCTTAAGCTATGCCGCTCGAAAATGTCCTTATCCGTCCATGTCGCCCGGAGCCACAATAATGACAATGTGGTCTGTTCAGTGTGCAACTCCTCGTACAAGAGCAAGGAAGCCCTGGACAAACACTTTGCTTACTGGCACGAGCCCGTCGAGTGTCCGCAGTGCTTCAAGATAGTCAAGAACACGCGCAACTACGACACCCACGTGAATGTGGTGCattcaaacaaaaagcgcTACACCTGCAGTGTATGCGAGAAAGGCTTCTACCACAAGAGCGAGATGGAGGCTCACAAAAGGCTCCACTCCCAGTCGTACAGTTGCGATCAGTGCAACTTCACCACCAGGAACAAGAAGTCCCTGTCTGTTCATACCCTGGGCCAGCACTTTAAGCGCTTCGCCTTCGAATGCAAGACGTGCGACAAACACTTTGGTCGACGCCAGGGACTGACCAACCACATACAACGTGTGCACGCCTCCAAGCATGTGTGCCGTAACTACATTGATAATGGCTGCGGGCGTTCTTTTGCCACCAGTTCCCAGCTGAACGTGCATTTGCGGAAGGTTCACAACTCCTCTATAGCAGCCGACGATGTGCTCGAAGAGGAGGAGTATGCCATCGCCAGACCGTCGGTAGCGAAGAAACGTTGCTTTGGAATCTTGAAAGATACCAAAGCTGACCTTATAGACGATTCTGAAGTTGATTTGGACACAATGAAAGACTCTGTCTATACCGTTGTacagaagaaggagaaggatggggaagaggaggagatggaggtggagcagaagcaggaggatGATGAATGTGAGGTGGAATTTGCCGAGGATGAGGCAGAGGaggaaccgaaaccgaaaccgatcCCTGGCTCAGGCAGAAAACATGGAAGAAAACACCGTTCGGATGATTAG
Protein Sequence: MSENPKINRSAPSCLHCGAFGAKLKYQDIFDEFGLELGLQQLLAKHFDLDATPKAKKQQFLCEECVNVLIRLFDIDELQKEQDAAIAKKKSAAQAAPAAKSASKTPPTPKSASKVPPNAAKPARKATPPEPQTKVEKVEQPDPKPSRRIIKNVSAPLPSAAVVAPVAAVVDKVKAPSKTTVKVVKHAPQDADHEQISALILNILNDDEPSEEDEADTGLPKSPQTTIAVTENEAMDVEVEEKEEQELDGLHIIYEHEDILLEEEVNTKPDVHPSRIKRQKTESQSEADNEEGEASNIVLFNFVEIKEKDDIDDLYEYLATVVRTSFEKLKFDWSTVCQLCTFKSASYEILLEHMLRVHKSRADVFRCPIEGCSLEIKGRKLLAMHLVVLHAPVADISIYGSCPECKMTFSNILQYNKHSCAHIIKKKRGIRLFCEMCALEFPSWKRFNFHNQFHLEKHRPRACFVCGYENTNIDELFQHLHYSHEPEGTLFCDLCDRTFRDAAVFLEHNTSHATVGSATYICGECLAPFETRGKLNSHTRTMHGNVISCELCSREFASEGTYNVHMKSHLIIERDVHVCGTCGQLSENQEKMDTHLGTEGSTCFGAESYVELLRDAYVCEYCTTYFKQKSDLQSHRETGVHNDGVFRCQPCEKNFTDMKLYRHHWRNYQQLRVDVAHRKLDICTFFMCDQKGCLAAYANWNSLYTHKRRTHDEAKEHQEKSAKPLQEWQCQFCLKLCRSKMSLSVHVARSHNNDNVVCSVCNSSYKSKEALDKHFAYWHEPVECPQCFKIVKNTRNYDTHVNVVHSNKKRYTCSVCEKGFYHKSEMEAHKRLHSQSYSCDQCNFTTRNKKSLSVHTLGQHFKRFAFECKTCDKHFGRRQGLTNHIQRVHASKHVCRNYIDNGCGRSFATSSQLNVHLRKVHNSSIAADDVLEEEEYAIARPSVAKKRCFGILKDTKADLIDDSEVDLDTMKDSVYTVVQKKEKDGEEEEMEVEQKQEDDECEVEFAEDEAEEEPKPKPIPGSGRKHGRKHRSDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00580943;
90% Identity: iTF_00517963; iTF_00517940;
80% Identity: -