Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018403.1:9035237-9038449[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0036 0.34 11.9 4.6 1 23 175 198 175 198 0.97

2 16 0.0018 0.17 12.9 2.1 1 23 242 265 242 265 0.95

3 16 0.011 1 10.4 5.7 1 23 330 353 330 353 0.96

4 16 0.0014 0.14 13.1 0.7 2 23 417 438 416 438 0.97

5 16 6.9 6.6e+02 1.5 1.1 1 20 551 570 551 572 0.88

6 16 0.015 1.4 10.0 0.5 1 23 581 603 581 603 0.94

7 16 0.00018 0.018 15.9 0.7 1 23 610 633 610 633 0.96

8 16 0.00077 0.073 14.0 0.8 2 23 642 663 641 663 0.95

9 16 0.0037 0.35 11.9 0.1 2 20 690 708 689 713 0.90

10 16 0.033 3.1 8.9 3.0 1 23 748 771 748 771 0.96

11 16 3 2.8e+02 2.7 1.2 3 22 780 799 778 799 0.95

12 16 0.023 2.2 9.4 1.4 1 23 808 831 808 831 0.97

13 16 4e-05 0.0038 18.0 0.1 1 23 853 876 853 876 0.97

14 16 0.038 3.6 8.7 0.2 1 23 886 908 886 908 0.94

15 16 6.4e-05 0.0061 17.4 3.7 1 23 914 936 914 936 0.99

16 16 3.1e-06 0.0003 21.5 1.5 1 23 942 964 942 964 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0036	0.34	11.9	4.6	1	23	175	198	175	198	0.97
2	16	0.0018	0.17	12.9	2.1	1	23	242	265	242	265	0.95
3	16	0.011	1	10.4	5.7	1	23	330	353	330	353	0.96
4	16	0.0014	0.14	13.1	0.7	2	23	417	438	416	438	0.97
5	16	6.9	6.6e+02	1.5	1.1	1	20	551	570	551	572	0.88
6	16	0.015	1.4	10.0	0.5	1	23	581	603	581	603	0.94
7	16	0.00018	0.018	15.9	0.7	1	23	610	633	610	633	0.96
8	16	0.00077	0.073	14.0	0.8	2	23	642	663	641	663	0.95
9	16	0.0037	0.35	11.9	0.1	2	20	690	708	689	713	0.90
10	16	0.033	3.1	8.9	3.0	1	23	748	771	748	771	0.96
11	16	3	2.8e+02	2.7	1.2	3	22	780	799	778	799	0.95
12	16	0.023	2.2	9.4	1.4	1	23	808	831	808	831	0.97
13	16	4e-05	0.0038	18.0	0.1	1	23	853	876	853	876	0.97
14	16	0.038	3.6	8.7	0.2	1	23	886	908	886	908	0.94
15	16	6.4e-05	0.0061	17.4	3.7	1	23	914	936	914	936	0.99
16	16	3.1e-06	0.0003	21.5	1.5	1	23	942	964	942	964	0.98

Sequence Information

Coding Sequence: ATGACCCGGACCTGCAGAATCTGTGGCGATACAAATGGACGTTACTGGATCGAGACGCCGGTGGAGAAGTATGCCGAGAAGACCTTCAGTCAGCTATTGCTGGAGTTAACCAAGATTGAGTTGACCATGGTCCAGGCCGAAAAGTTGCCCCACTGGCTGTGCTCCAGTTGCTCCCAGAGGCTGGAGAGCGCCTACGATTTTGTGTTGCAGGCGAAACAGACGCACAAATTGTGGCTGCAACAGCTGGAGGATACGGGGCAGATAATGAGCTCTGGGGGGGCATTGGAGTGCCTGCGCGAGACCCCTATACATCTGTTTGAGATCGAGGGTGCTACCATCAAAACCGAAGCGCTAGAGTCAACGGTTGCAGATGCCGGGAATAGCTCCTGCGATCCTCTAGTCCGCACACGCATCAAAAAGCGTACCATCTTTCACTTCAGCGATACGGAGGATGACCAGGATGATGTGCCGCTTAGGCAACGCAGGACTGGCAGCCAAGCGAACAGCTCATCAGCAAAGCTGCACAAGTGCAATCTGTGCGCCAGATCCTTCAGATATATCACAAATCTCTATCGCCACAAGAAAAGAGATCACGGCTATCCAGGGCATTCTAAAAGTGAGAGCACCGAATCATACCCGGAAAAGACACAAAAAAGCGACGTGGCAGCGCAGGACAGCTCCAATTTAGAaCAAAACGATGATGACGAGGATGATGATAACTACTACAAATGCGATCAGTGCGACAAGTCCTATAAGCACATAATGGTGCTTATCAAGCACAAGCAGAATGCCCATGAAGCTAATCAGCTGCCAATCCGATCTGGGCCCAAGCGAAGAAACAGAAGGGACGTGGGTGAGGCGGCAAGTCCAGCTTCTTCCGGGAAATCCACACAACGAGCCAGAATCAGCACCGATACCCTGGTCCATAGCCTCATCAAAGCAGTGGAGCTGTCGGATGAGGATGGAAACAGCGGCAGCGATAACTATTACAAGTGCGATCAGTGCCACAGATCATACAAATACATTGTAAGCCTCATCAAGCACAAGCACAAGGAACATTCGGAAGCTGACAAAAACTGGGACGACGAGGACAATCAACCATTGGCCTCCACATCTACCtgcgccactgccactgccactgccgcctcaggctcaggctcaggctctcCCACCAAGGCATCGCGAATCAATCGTCGAGTTCAGGGCTTCGATCCGCATCGCTGCGAGCCGAATGGTGCGAAGGAGATTCAGTGCATGATCTGTCTGCGGAAATTCACTAAATTGCGTGAGCTGAGAGATCACCTCAGGGCGCATCCCACCGACTTTAATTTCCAGGCGCACGGTGAGCCCATCGAACGCATTGCCGAGGGCTTCTTCAAGACGGCTGTGGAGTCCACTGTGGAGGGTTTGAAGAGCAGGATTCTGCACGATCTAAGGATGGGTGCCTTCGGACGCTTCTATTCCATTACCAACGAGGCGCGCTACGAGATGAGTCTGGACAGCTCGGACACGGATAGCGATGGCGATGCAGATGTTGTACTGAGACGAAGCTATGCCTGCGAGCTATGCGACTCTCCGGAAGCCAGGTGGCCGCGCAAGTATCAGCTGCACGAGCATCACAGACAGCAGCACACCTGGGAAGAGGCTCCGCATGTCTGCCAGCGCTGCGACTCTCGTTTCCTCAGTCTCCAGCTGCTGGAGCATCATACTCTACAGCTCTGCCAGAACACCCTGAAGCGTTACATGTGCGACAAGTGCCCGCAGCGCTTCTTCTGGCGAAGAAATCTGCGTGCCCATCTGGTCGAGCACAAGAGCAAGCAAGACAACTATCCGTGCGACCAGTGCCAGCGCAGCTTTCAGGATAAAAGCGCCGTGACCAAGCACAAGCTGATGATGCATCGCGATGAAAAGAATCAGCTTATTCCCTGCCGCTGGTGCTCACGGACCTTCTATCGTCCCGCCCTTCTGCACAAGCATGTCGAACGGCATGGCTTCACCGGCGACGATTTGCCCTTGGCTGAGACACTGCTAGCCGATGCAGCCAAGCCATCGGGCCCAAAGACTGTCCAGTGCAAGATCTGTGACCTGCAGTTCGTAAGCGTCGCCGATCTGCGCCGCCACAATGCCATGCTCGGCCACAGTGAGCGACTAACCGAGTACATGATCAGCACCGAGGCTGGCTTCGAGCTGTTATTGGAGGACACAGACGACAGCGATGACGACACTACGGCGGGCAGGTCCTACTCCTGCGATCTCTGTCAGATGACGTTCCATCGCCGCAGGGAGATGAGCGAGCATCAGTATTCACTGCACGCCTTTGACAAGTTGCCATATGGTTGCAAACATTGCATTTATAAGACCGTGGATAAGCTCATGCTGGAGCATCATCTGCGCACACAATGTCTGAACAACGAGAAGCCATTCAGCTGCTCCCGCTGCAAATACAAGTTCATGTGGAAGGAGAACCTGGAGCAGCACTTGGCCACTCAGCATCCCAAGCAGCCGCCCACCCATGAGCAGTCGTCCATGCCCTTGAGGAGAAGAAGACGCTTCAGATATCAATGCCCACAGTGCTGGCGCTCGTTTGTGGTGCAGCCCAGCCTCGATAAGCATATAAGGGACATGCATGTGGCCAAGAGGAATCCGGGCAAGAAATACCTCTGCTCCCTCTGTGGCCTGGAGTCGCTGACGCCCAACAAGCTAAACATCCATATGCGTCGCCACAACGGAGAAAAGCCCTTCAAATGCGATCTCTGCGACATGCGCTTCACAGTCCACTACGAGCTGAAGGTCCATCGGCGGAAGCACACCGGCGAGCGGCCCTACCAGTGCACCTTCTGTGACAAGCAGTTCGCCCGACCCGACAAGCTGAGACGGCATGTCTACATGCACAGTGCTCGTCGCTAG
Protein Sequence: MTRTCRICGDTNGRYWIETPVEKYAEKTFSQLLLELTKIELTMVQAEKLPHWLCSSCSQRLESAYDFVLQAKQTHKLWLQQLEDTGQIMSSGGALECLRETPIHLFEIEGATIKTEALESTVADAGNSSCDPLVRTRIKKRTIFHFSDTEDDQDDVPLRQRRTGSQANSSSAKLHKCNLCARSFRYITNLYRHKKRDHGYPGHSKSESTESYPEKTQKSDVAAQDSSNLEQNDDDEDDDNYYKCDQCDKSYKHIMVLIKHKQNAHEANQLPIRSGPKRRNRRDVGEAASPASSGKSTQRARISTDTLVHSLIKAVELSDEDGNSGSDNYYKCDQCHRSYKYIVSLIKHKHKEHSEADKNWDDEDNQPLASTSTCATATATAASGSGSGSPTKASRINRRVQGFDPHRCEPNGAKEIQCMICLRKFTKLRELRDHLRAHPTDFNFQAHGEPIERIAEGFFKTAVESTVEGLKSRILHDLRMGAFGRFYSITNEARYEMSLDSSDTDSDGDADVVLRRSYACELCDSPEARWPRKYQLHEHHRQQHTWEEAPHVCQRCDSRFLSLQLLEHHTLQLCQNTLKRYMCDKCPQRFFWRRNLRAHLVEHKSKQDNYPCDQCQRSFQDKSAVTKHKLMMHRDEKNQLIPCRWCSRTFYRPALLHKHVERHGFTGDDLPLAETLLADAAKPSGPKTVQCKICDLQFVSVADLRRHNAMLGHSERLTEYMISTEAGFELLLEDTDDSDDDTTAGRSYSCDLCQMTFHRRREMSEHQYSLHAFDKLPYGCKHCIYKTVDKLMLEHHLRTQCLNNEKPFSCSRCKYKFMWKENLEQHLATQHPKQPPTHEQSSMPLRRRRRFRYQCPQCWRSFVVQPSLDKHIRDMHVAKRNPGKKYLCSLCGLESLTPNKLNIHMRRHNGEKPFKCDLCDMRFTVHYELKVHRRKHTGERPYQCTFCDKQFARPDKLRRHVYMHSARR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575022;
90% Identity: iTF_00481028;
80% Identity: -