Basic Information

Insect: Drosophila helvetica
Gene Symbol: -
Assembly: GCA_963969585.1
Location: OZ018401.1:8698706-8703075[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 1e-07 1e-05 26.2 1.8 2 23 135 156 135 156 0.97

2 9 1.4e-07 1.3e-05 25.8 0.5 1 23 162 184 162 184 0.98

3 9 1.2e-07 1.2e-05 25.9 1.1 1 23 190 212 190 212 0.98

4 9 7.4e-07 7.1e-05 23.5 0.7 1 23 218 242 218 243 0.95

5 9 4.4e-05 0.0042 17.9 3.1 1 23 248 270 248 270 0.97

6 9 0.00052 0.05 14.5 3.2 1 23 276 299 276 299 0.97

7 9 0.00049 0.047 14.6 1.3 1 23 305 327 305 327 0.98

8 9 4.2e-06 0.0004 21.1 0.8 1 23 332 354 332 354 0.98

9 9 0.001 0.095 13.6 0.5 2 23 361 385 360 385 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	1e-07	1e-05	26.2	1.8	2	23	135	156	135	156	0.97
2	9	1.4e-07	1.3e-05	25.8	0.5	1	23	162	184	162	184	0.98
3	9	1.2e-07	1.2e-05	25.9	1.1	1	23	190	212	190	212	0.98
4	9	7.4e-07	7.1e-05	23.5	0.7	1	23	218	242	218	243	0.95
5	9	4.4e-05	0.0042	17.9	3.1	1	23	248	270	248	270	0.97
6	9	0.00052	0.05	14.5	3.2	1	23	276	299	276	299	0.97
7	9	0.00049	0.047	14.6	1.3	1	23	305	327	305	327	0.98
8	9	4.2e-06	0.0004	21.1	0.8	1	23	332	354	332	354	0.98
9	9	0.001	0.095	13.6	0.5	2	23	361	385	360	385	0.95

Sequence Information

Coding Sequence: ATGGACACCATCTGTAGGCTCTGTTTTCAAACAGCAACGTTATTCCAAGTGCCCGGCTATAGCATACCCACGTGCGTACGCTGctccgaacagctgacaaacaATTCAAACTTCCATCAAGCGGTGCGGGGGGCAGAAGGTGGATCGACTGTTTCCGTATCGGCGGCCGTTgcagcagccgctgccgccgccgtcgCATCGTCATCGACGTCCAGTGATAGCGACGTTGCTGCAGTCGCGCAGCAGCTGACCAACGGCAGTAATGCTGCTGCCGTCGCAGTGCTGCAGctacaccagcagcagcatcagcagcaacaacaaatgcaATCATCGAGCTCTTCCGAGAATCTACAATCGCAGGACGATTCTGAAGATGTGGATCTGATATTCAATGAGGAGGGCTCCTGCCCCCTTTGCAACAAGACGTTCTCGCGCAAATCCTCGCTGATGACGCACATACGGAACCACTCGGCGGAGCGTAAATTTGTTTGCACCTACTGCAACAAAGGCTTCACCCAGGCGGCCAATCTGCGGAATCATGAACGCATTCACACGAACGATCGCCCATACCAGTGCGTCGATTGTGGCAAGACCTTCACACAGATCACGAACCTAAATAATCACCGCCGCCTGCACACCGGCGAGCGGCCCTTCGTCTGCAATGAGCCCGAATGCGGACGCAGCTTTGCCCAGGTGACCAATCTGAACAACCACATGAAGTCACACCACAAGGTGCAACAATACTGCTGCAACGTATGTAACAAGAAGTTCACTCAGGTCACCTCACTGAACCAACACCTGCAGGCGCATGCCGGTGTCAGCGGCTACTTTTGTCCGCGCTGTCCCGATAAGAGCTTCAAGCTGCAGTCACAGTTGCACACGCACATGAAATCGCACGGTCTGGCCTTCCCCTACGAGTGCGGCAAGTGCGACGAGAAGTTCTTGCAGCAGGCCCACCTCGACCAGCACCTGAAGATGCACGACGAGTTCAAGTTCAAGTGCGACATCTGCCCCAGCAGCTTCAACCAAGAgtcgctgctgaagaagcatGTGCAGCGGCATGTCGAGGGTCGGTATCTCAGTTGTCCGGTGGCCAACTGTACGGAATCGTTTGCCGTACGCCAGCACCTGTCCAAGCATTTGCTCACAAATCACTCCCATCACGAGCTGCCGCCACCGAAGCGCTCCAAAAAGACGGTCACGCTGCAATCGCCACAACAGCCACTGGCGATGATCGGCCAGCCACTATCGCTGCAGCACACGACGGGGCAGCGTGGACGACCGCCGAAAAATAAGAACAAAACGACCGGCACATTGGCCGCCACGGCTATCAAGATTGAGATCAATGAGCCGCTACACAGCCAGCATATCATCAGCAGTGCCAGTGGACTCTCCATCCAacagcagatcaaccagcacATGCAACAGCAGGCGCAACagcaggcgcagcagcaggcgcagcagcaacaccagcagcagcagcagcatctacATCTGTCCATGGGCCAGGCGGTCAAGGCGCGCTTCATACCCACCAAGTAG
Protein Sequence: MDTICRLCFQTATLFQVPGYSIPTCVRCSEQLTNNSNFHQAVRGAEGGSTVSVSAAVAAAAAAAVASSSTSSDSDVAAVAQQLTNGSNAAAVAVLQLHQQQHQQQQQMQSSSSSENLQSQDDSEDVDLIFNEEGSCPLCNKTFSRKSSLMTHIRNHSAERKFVCTYCNKGFTQAANLRNHERIHTNDRPYQCVDCGKTFTQITNLNNHRRLHTGERPFVCNEPECGRSFAQVTNLNNHMKSHHKVQQYCCNVCNKKFTQVTSLNQHLQAHAGVSGYFCPRCPDKSFKLQSQLHTHMKSHGLAFPYECGKCDEKFLQQAHLDQHLKMHDEFKFKCDICPSSFNQESLLKKHVQRHVEGRYLSCPVANCTESFAVRQHLSKHLLTNHSHHELPPPKRSKKTVTLQSPQQPLAMIGQPLSLQHTTGQRGRPPKNKNKTTGTLAATAIKIEINEPLHSQHIISSASGLSIQQQINQHMQQQAQQQAQQQAQQQHQQQQQHLHLSMGQAVKARFIPTK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00533229;
90% Identity: iTF_00574989;
80% Identity: -