Dhaw003269.1
Basic Information
- Insect
- Drosophila hawaiiensis
- Gene Symbol
- Znf639
- Assembly
- GCA_037043685.1
- Location
- JBAMBA010000101.1:2696428-2699582[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.014 0.92 10.0 0.4 3 23 287 308 286 308 0.91 2 10 0.00015 0.0099 16.2 0.5 6 23 317 334 317 334 0.99 3 10 8.9e-06 0.00059 20.1 0.3 1 23 340 363 340 363 0.98 4 10 0.00012 0.0081 16.5 0.5 1 23 375 397 375 397 0.98 5 10 0.0003 0.02 15.3 7.7 1 23 404 427 404 427 0.96 6 10 1.3e-05 0.00083 19.6 1.8 1 23 433 455 433 455 0.96 7 10 0.31 21 5.8 0.9 2 23 464 485 463 485 0.96 8 10 0.00012 0.0079 16.5 2.8 2 23 491 513 490 513 0.95 9 10 1.9e-07 1.2e-05 25.4 0.7 2 23 520 541 519 541 0.97 10 10 0.00019 0.012 15.9 4.4 1 23 547 570 547 570 0.96
Sequence Information
- Coding Sequence
- ATGATCTGTCGCTTGTGTTTAAAAAGCATAAACGCAAACAATGCTGTCTATCTGTTCGAAACGAACGACACCCTGGCCGAATCCTCGCTGCTCAAGATAATAGCCAAGTTCCTGCAGCTGGAGATAATGCCCGATGACAACATCTCGACGAACATTTGCCACGATTGCTGCGAACATTTGGAGGACTTTAACAACTTCTGGCAGCTGGTCGAGCAAAAGCAGTTAACGCTTAAAAAGGAGTTCCTCAACGTGGATGTCGATTGCGTGGCCCTCAAATGGACGGGCGGTATCGATGTGGATGTCAATATAGATGAGCTGCCGCTGGTCACCGACGAGATGGACGAAAAGCCCCTCGATATACACAATCTCAGTCTGCTTGGCAGCGTTCTCGATCTACTACCCCTGCACGTCTTCAATcctgacgacgatgatgatgacgacgacgatgtcgATGAGAAGCCCATAATGAATGAGAGCAGCGATAGCACGCCGCACACTTCCTCAGATGATGATGATGAAGTGCCTCTGGTGAAGCTGAAGCACAAGCTCAAACCAAAGCGGAAGGGACGCATTGTGGCACGCAGTGAGCAGCGCCGGCTAACGCTCGCCCAGGAGCTGAATCAGCTGCTGGATGACACCGACACTGGATGCGACAACGATAACGATGGCGATAGCGTCAATCGAGGGCGTCGCAAACAGCggaacacaaacagaaacacaaacacaaataataatgcgCCAACGGATACACAGAAGAGCGAGCTGCAGGCGGCCATGGAACGGAAGCCGAAGGGCTGCTCGCGGGCGCAGCTATCGAAGCGTTACGAGGAGGCCATCGCCAGCTATATGAATGCCGACTGTGATCTGTGCGACTTCAGCACCAAGTACCTGTCCCAGTTGAAGGTCCACTTCCTGGAGGTGCATCAGCGCGACGCGTATCTCAAGTGCTGCAACAAGGTCTTCAATCGCGCCTCCAAACTGATGGATCACATACGCAAGCACATCAATCCCAAGCTATTCACttgttCGATTTGCAACAAGTCGCTAAATTCTCAGGATTATCTGGCCACGCACATTGAGACGGTGCACAACAAGGTCGCCCAGATTGGCAAGGTGCTGAAGTATCCGTGTCCGAAATGCGAGCGCACGTTCAGCAGCGAGAGGCGTTTGGGTAATCATTTGCTGAAGCACGACACGGATCAGTTGGAGCACAGTTGCCACATATGCCACAAGAGCTTTGCGAATGTGCATCGGCTGCGTCGGCATATACAGTCGATCCATGAGGATGTGCATCCGCATGTCTGCGACATTTGTGGCAAGAAGTTCAAGTTTAAGCCATCGTTCGAGCGCCACTTGCTGGAACATCAGGGTGTCGTCGCACCAGCGATGGAGTGCTCCGTCTGCGGTGTCTGGCTGAAGAACGAGCACAGTCTGCGACTGCATCGATTTACGCACGATAGCACCGATACCGTCTGTCCCCATTGCTCCAAGACGTGCAGTTCGCGGACAGCGTTGCGTGCCCATGTTAAATATGCTCACAAGCTGACCACAAACCTGCAGTGCACGTACTGCGAGAAGAGCTTCAAGCAGCAGCGCAACCTCGAGGAGCACATGGCGATCCACACTGGCCTCCAGCTATACAATTGCCCCCACTGTCCCAAGGAGTGCAGGTCGCGCTCCAACATGTATGTCCACATCAAGCAGAGGCATGCGGACGAGTGGCTCAAAGCCAAAATGGCACGCTCCCATAATCCGCAGTTTAAGCCGCACGCCTAA
- Protein Sequence
- MICRLCLKSINANNAVYLFETNDTLAESSLLKIIAKFLQLEIMPDDNISTNICHDCCEHLEDFNNFWQLVEQKQLTLKKEFLNVDVDCVALKWTGGIDVDVNIDELPLVTDEMDEKPLDIHNLSLLGSVLDLLPLHVFNPDDDDDDDDDVDEKPIMNESSDSTPHTSSDDDDEVPLVKLKHKLKPKRKGRIVARSEQRRLTLAQELNQLLDDTDTGCDNDNDGDSVNRGRRKQRNTNRNTNTNNNAPTDTQKSELQAAMERKPKGCSRAQLSKRYEEAIASYMNADCDLCDFSTKYLSQLKVHFLEVHQRDAYLKCCNKVFNRASKLMDHIRKHINPKLFTCSICNKSLNSQDYLATHIETVHNKVAQIGKVLKYPCPKCERTFSSERRLGNHLLKHDTDQLEHSCHICHKSFANVHRLRRHIQSIHEDVHPHVCDICGKKFKFKPSFERHLLEHQGVVAPAMECSVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCSSRTALRAHVKYAHKLTTNLQCTYCEKSFKQQRNLEEHMAIHTGLQLYNCPHCPKECRSRSNMYVHIKQRHADEWLKAKMARSHNPQFKPHA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00610817;
- 90% Identity
- iTF_00553200;
- 80% Identity
- -