Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: ham
Assembly: GCA_037043685.1
Location: JBAMBA010000106.1:2548938-2573883[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.54 36 5.0 0.0 2 21 294 313 293 316 0.87

2 9 0.0081 0.53 10.8 0.1 1 23 323 346 323 346 0.92

3 9 1.7e-07 1.1e-05 25.5 1.7 1 23 352 375 352 375 0.96

4 9 3.2e-07 2.1e-05 24.6 1.5 1 23 381 403 381 403 0.97

5 9 8.2e-05 0.0054 17.1 3.8 1 23 409 431 409 431 0.97

6 9 0.0018 0.12 12.8 2.0 2 21 439 458 438 459 0.94

7 9 6.3e-09 4.2e-07 30.0 1.3 1 23 955 977 955 977 0.99

8 9 3.4e-07 2.2e-05 24.6 0.9 1 23 983 1006 983 1006 0.97

9 9 4.3e-05 0.0028 17.9 6.8 1 23 1012 1034 1012 1034 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.54	36	5.0	0.0	2	21	294	313	293	316	0.87
2	9	0.0081	0.53	10.8	0.1	1	23	323	346	323	346	0.92
3	9	1.7e-07	1.1e-05	25.5	1.7	1	23	352	375	352	375	0.96
4	9	3.2e-07	2.1e-05	24.6	1.5	1	23	381	403	381	403	0.97
5	9	8.2e-05	0.0054	17.1	3.8	1	23	409	431	409	431	0.97
6	9	0.0018	0.12	12.8	2.0	2	21	439	458	438	459	0.94
7	9	6.3e-09	4.2e-07	30.0	1.3	1	23	955	977	955	977	0.99
8	9	3.4e-07	2.2e-05	24.6	0.9	1	23	983	1006	983	1006	0.97
9	9	4.3e-05	0.0028	17.9	6.8	1	23	1012	1034	1012	1034	0.98

Sequence Information

Coding Sequence: ATGTTATTCGATCGTTATGTTATGTCAGGCTCTAACGGCGACGATTACGATCCGAGCGTCGTGCGCCatcaccaccatcatcatcaccactTGGATCTCAGCAGTGGGGCGCCGGCATTTGCACCGTTGCCGCCGGCGCATCTAACCTCCGGTCAGACGAGGCCCGAGGAATCcagcagcagcagcatcaagcagcagcagcagcaacagctgcaacattcACCGCCCACGCTGCCGCCTGCCTCAGCGTCCGTCTCCAACGGTTCCAGCATGGAGCATCTGTTCAATGACAAGGCGCAGGCGGAACGCTTTCTGCTGGAGATGGCGCGTCTGCGCGAACCCGTCTGTGATCTGGATATACGTGATACTGGCGTCTATGCCAAGACACATCTGCCCCGAGGCACCCGCTACGGACCCTTTCCCATGCGACTCTGCCAGCAGCCCAGCGATCGACACTTGGCCTGGGAGGTGATTGCCGGCCCATTGTTTCACGGTTGGCTGGAACCTCATCGGATGAATTTCATCATTGCCGGCTAtCTGTGGTACGAGACGAAACGGGACGTAAATGCTGGCGCTGAAATTGTTGTCGATGCCCGTCCGAAAACCCCCTACGATATCAGCGACAGTTTCATGAACGGGGCAGGGGCTGCCGGCGGCGCGGGCAGTGCAACATCGGCGGGGgccagcagcacagcagccgctacagcggcagcagcagcagcaactgcaatggcagcggcagcaacatccagcaacaacaacaacaacaatggttcGTTGCCAGGCGATGATCGAAGCGATCGTGATAATGGCTTTTATAGCGGAGACGAGAAGAAAGGCGACAACGATTTCACGGACGACGAGAACGGTTTCGATATACGCTGTGAGGTGTGTGATAATGTCTATACGGATTTGGAACGATTGGACGATCATTTAGTGGGCGCACATCATTTCAAGCGCGGAGAATTCCCCTGCGAGCTTTGTGCCCAGCGTTTCAGCCATCGTCCTTTGCTAATCAAACACGGAGCCATCGCCCATAATAATATACGCAAATATTCCTGCGAGAACTGTTCCAAGGTATTCTGTGACCCATCGAATTTACAGCGTCATATTCGCGCCTATCACGTCGGCGCTCGCAGTCACCCGTGTCCGGAGTGCGGtaaaacatttgccacatcATCGGGCCTcaagcagcatcagcacaTCCACTCATCGGTTAAGCCGTTCGCCTGCGAGGTGTGCTTCaaggcgtatacgcaattctCCAATCTGTGCCGCCACAAGCGGATGCACGCCGATTGTCGCATGCAGATCAAGTGCAAGAAGTGCAACACGAGCTTCAGCACGGTCACCTCGCTGTCCAAGCACAAGAAGTTCTGCGATACCTCGGACAGCTTtcgcagccagcagcagagtCGCCTACAACACGCCCACGATCGCCACCatcaccagcatcagcatcagcatcatcagcagcagcagcagcatcagcagcaactctCGCAGCATACGCAGCCGCCATCACTTCTGTTGCCACCCGGTGCCCATCAGCGACTTGCCGCCGAGACGTCAAATTCGGCCATGGCCACGCCACCAAATCACATATTTATGATGCATCCGACACCGTCGTTCTTTGCTGGCTTTCCCAATTACGGGCTGCATAGCTTATTTCCCGGCTTCCAGCAGGCTGGCAATTTTCCGCTATCACACATGTTTCCCAATTCGCAGCTGGGCGATATGAGTCGCGGCCTGCCGCCAATTGTCTCCCCAACTGCCGCAttccaacagcagctgcagtcagCGATGAGCATGAAAACAGAATCGCCACGTTTGAAACGCGACTCCAGCACACCGGAGCGTAAGCCGATCAAATCGGAGCTGCATCCCTCCGACGAGGAGTCCAATTCGCTCAGCTACGAAGAGCTCAAGCTGAAGTCGAGCAAGTTGCAGCAGGAGTCGGGCAAGGTGAAGCGGGAACTTAAATCGGAGGCCAGTTGCACCCAGCAAGCCGACGAGGACAGCGATCATAATAATAGTGACAATGATAACGATAATGATATTGAAAATGACAGGAAATCGATTGACATTGTTAGCACTCCGCCGCCAGCGGAAACGCAAATGAAGACCGAACCGGAAGCGGCGGATGTGGACAAGAGCAGCGCTGAACTGCCGCTGGATCTGTCCATCAGTCGCAAGCGTCGCAGTTCGCTGTGCGCCGCCTCCACGCCCGCCCCGCTCTCCATATCGCTGTCGAGTCGTGAGCCATCGCCCGAGCTGGACGCCGAGGACGATGAGGaagaggatgaggatgaagtGGAGCTGCTGGCACCGCCGGCAAAGCAACCAAAGCACAGTTCCGGCGAATCGAGCACTTCCCGTCAGTCGTACAAGGGCAGCAGTCCGGTGCCAAGTGCAAGTGCCTCTCCGGGACCAACACCCTCACCGTCGCCACCCATCAGCACTGGCGGCGAGTTGAGCAGCATGTCGGAGAGTGCCGCTGCCaatgcaacggcaacggcaacggcatcggcagctgccgcagccgcagcagcagcggccgccTCAGCGATGGCCTGTCCCCGGCAACTGCATCcgcagctgttgctggagGAGCTCTACCGTACACGATTCCCAACGCAGCCGTTTCATTTTTTAGGCCAAATGGGCGGACGGCCAGGTTTTGAGTCACTAAAGTCGCCAGCGATGGGTGCCGCACATGCGCCCATCAGTGGCGGCGGCTCGCGTCATCTGCCGTTTCCGCCCGAGCATAATTTCCACGAGGCACTCCGTGCCGCTGGCTTGGCGGCCGCTGCCGCCCGTCCGCCGACAGCGTGCAACGCCAGTGGCAAGCTAAAGGATCGCTATACGTGCAAATTCTGTGGCAAGGTATTTCCACGTTCCGCGAATCTAACACGGCATCTGCGCACCCACACCGGCGAACAGCCGTACACGTGCAAGTATTGCGATCGTGCCTTCAGCATCTCATCGAATCTGCAGCGTCATGTGCGCAACATCCACAACAAGGAGCGACCATTTCGCTGCCACATGTGCGATCGCTGCTTTGGCCAGCAAACGAATCTCGATCGGCATCTCAAGAAGCACGAGGCAGATGCTGGCGGCTTCGAGTACAACGATTCGCCCAGTTCGAATGAGGCAAATGATCGCGATGAGGCCTGCTTCGATGATATCCGTTCGTTTATGAAACGCGTCTATACGCCCACCAGTTTGGGCGGGGCGGATGGGGACACGGAGGAGTATGCGGGCAGTGATGATCAGTTGTCCGTTTCCACGCGTCAGTCTGCCAACTTTGACAAGGAGCTGCTCTCAAAtggcaacatcatcaacatcaacaacaacaatagcagcaataacaacaacaacaacaacaacaacaatagcaacaacaacaacaatagcaacagcagcagcaacaatcagaCTTTAAATACATCGGAAACAATTGCCGTGAGCACCTAA
Protein Sequence: MLFDRYVMSGSNGDDYDPSVVRHHHHHHHHLDLSSGAPAFAPLPPAHLTSGQTRPEESSSSSIKQQQQQQLQHSPPTLPPASASVSNGSSMEHLFNDKAQAERFLLEMARLREPVCDLDIRDTGVYAKTHLPRGTRYGPFPMRLCQQPSDRHLAWEVIAGPLFHGWLEPHRMNFIIAGYLWYETKRDVNAGAEIVVDARPKTPYDISDSFMNGAGAAGGAGSATSAGASSTAAATAAAAAATAMAAAATSSNNNNNNGSLPGDDRSDRDNGFYSGDEKKGDNDFTDDENGFDIRCEVCDNVYTDLERLDDHLVGAHHFKRGEFPCELCAQRFSHRPLLIKHGAIAHNNIRKYSCENCSKVFCDPSNLQRHIRAYHVGARSHPCPECGKTFATSSGLKQHQHIHSSVKPFACEVCFKAYTQFSNLCRHKRMHADCRMQIKCKKCNTSFSTVTSLSKHKKFCDTSDSFRSQQQSRLQHAHDRHHHQHQHQHHQQQQQHQQQLSQHTQPPSLLLPPGAHQRLAAETSNSAMATPPNHIFMMHPTPSFFAGFPNYGLHSLFPGFQQAGNFPLSHMFPNSQLGDMSRGLPPIVSPTAAFQQQLQSAMSMKTESPRLKRDSSTPERKPIKSELHPSDEESNSLSYEELKLKSSKLQQESGKVKRELKSEASCTQQADEDSDHNNSDNDNDNDIENDRKSIDIVSTPPPAETQMKTEPEAADVDKSSAELPLDLSISRKRRSSLCAASTPAPLSISLSSREPSPELDAEDDEEEDEDEVELLAPPAKQPKHSSGESSTSRQSYKGSSPVPSASASPGPTPSPSPPISTGGELSSMSESAAANATATATASAAAAAAAAAAASAMACPRQLHPQLLLEELYRTRFPTQPFHFLGQMGGRPGFESLKSPAMGAAHAPISGGGSRHLPFPPEHNFHEALRAAGLAAAAARPPTACNASGKLKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYTCKYCDRAFSISSNLQRHVRNIHNKERPFRCHMCDRCFGQQTNLDRHLKKHEADAGGFEYNDSPSSNEANDRDEACFDDIRSFMKRVYTPTSLGGADGDTEEYAGSDDQLSVSTRQSANFDKELLSNGNIININNNNSSNNNNNNNNNNSNNNNNSNSSSNNQTLNTSETIAVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01327310;
90% Identity: iTF_00513601;
80% Identity: -