Basic Information

Insect: Drosophila hawaiiensis
Gene Symbol: -
Assembly: GCA_037043685.1
Location: JBAMBA010000204.1:2385016-2389537[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0005 0.033 14.6 0.9 1 23 210 232 210 232 0.97

2 24 0.00036 0.024 15.0 4.1 1 23 238 260 238 260 0.98

3 24 0.019 1.2 9.6 0.7 2 23 293 314 292 314 0.96

4 24 0.0014 0.093 13.2 1.9 1 23 389 412 389 412 0.94

5 24 1.1 72 4.1 0.9 2 22 422 442 422 442 0.95

6 24 4 2.7e+02 2.3 0.4 1 19 451 469 451 471 0.91

7 24 0.0044 0.29 11.6 0.5 1 23 589 612 589 612 0.96

8 24 0.0084 0.56 10.7 0.1 1 22 621 642 621 642 0.95

9 24 0.007 0.46 11.0 4.4 1 23 651 674 651 674 0.97

10 24 8.3e-05 0.0055 17.0 0.5 2 23 688 709 687 709 0.97

11 24 1.4e-05 0.0009 19.5 5.2 1 23 715 737 715 737 0.98

12 24 0.11 7.3 7.2 1.0 1 23 876 899 876 899 0.95

13 24 0.0046 0.31 11.5 2.2 1 22 906 927 906 927 0.96

14 24 0.59 39 4.9 0.4 1 20 936 955 936 959 0.86

15 24 5.6e-05 0.0037 17.6 1.6 1 23 983 1005 983 1005 0.97

16 24 0.00042 0.028 14.8 0.7 1 23 1012 1034 1012 1034 0.98

17 24 0.12 8.2 7.0 0.0 2 21 1061 1080 1060 1081 0.94

18 24 0.037 2.5 8.7 4.0 1 23 1126 1149 1126 1149 0.96

19 24 0.0056 0.37 11.3 1.8 1 23 1186 1209 1186 1209 0.97

20 24 1.3e-05 0.00085 19.6 0.1 2 23 1261 1282 1260 1282 0.95

21 24 4.4e-05 0.0029 17.9 2.9 1 23 1288 1310 1288 1310 0.99

22 24 4.1e-05 0.0027 18.0 2.2 1 23 1316 1338 1316 1338 0.96

23 24 2.7e-07 1.8e-05 24.9 2.6 1 23 1344 1366 1344 1366 0.99

24 24 0.00049 0.032 14.6 0.4 1 22 1372 1393 1372 1396 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0005	0.033	14.6	0.9	1	23	210	232	210	232	0.97
2	24	0.00036	0.024	15.0	4.1	1	23	238	260	238	260	0.98
3	24	0.019	1.2	9.6	0.7	2	23	293	314	292	314	0.96
4	24	0.0014	0.093	13.2	1.9	1	23	389	412	389	412	0.94
5	24	1.1	72	4.1	0.9	2	22	422	442	422	442	0.95
6	24	4	2.7e+02	2.3	0.4	1	19	451	469	451	471	0.91
7	24	0.0044	0.29	11.6	0.5	1	23	589	612	589	612	0.96
8	24	0.0084	0.56	10.7	0.1	1	22	621	642	621	642	0.95
9	24	0.007	0.46	11.0	4.4	1	23	651	674	651	674	0.97
10	24	8.3e-05	0.0055	17.0	0.5	2	23	688	709	687	709	0.97
11	24	1.4e-05	0.0009	19.5	5.2	1	23	715	737	715	737	0.98
12	24	0.11	7.3	7.2	1.0	1	23	876	899	876	899	0.95
13	24	0.0046	0.31	11.5	2.2	1	22	906	927	906	927	0.96
14	24	0.59	39	4.9	0.4	1	20	936	955	936	959	0.86
15	24	5.6e-05	0.0037	17.6	1.6	1	23	983	1005	983	1005	0.97
16	24	0.00042	0.028	14.8	0.7	1	23	1012	1034	1012	1034	0.98
17	24	0.12	8.2	7.0	0.0	2	21	1061	1080	1060	1081	0.94
18	24	0.037	2.5	8.7	4.0	1	23	1126	1149	1126	1149	0.96
19	24	0.0056	0.37	11.3	1.8	1	23	1186	1209	1186	1209	0.97
20	24	1.3e-05	0.00085	19.6	0.1	2	23	1261	1282	1260	1282	0.95
21	24	4.4e-05	0.0029	17.9	2.9	1	23	1288	1310	1288	1310	0.99
22	24	4.1e-05	0.0027	18.0	2.2	1	23	1316	1338	1316	1338	0.96
23	24	2.7e-07	1.8e-05	24.9	2.6	1	23	1344	1366	1344	1366	0.99
24	24	0.00049	0.032	14.6	0.4	1	22	1372	1393	1372	1396	0.91

Sequence Information

Coding Sequence: atgttgcCGACGAATATTTGTCGCACGTGTGCGTTGCAAGATGACAACTTGTTGGCATTGGCAACGCGGAGTGAGAAATACGCAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAAACGatCCATTGCTGGAGCATACAGATGATAAGCTACCACAGCATTTGTGCGGCCAATGCTTGAGCCAACTGGAAGCTGCCTATGCATTTGTGGTGCAGGCACGCCAGACACAGGAGCAACTGTTGCTACAGCTACGTAACGGATTGCAGACACAGTGCCTGGACGAAACACCCATTGATATAAGCACGGAGCACATCAAAATCGAAACAGACATTGACCTAGATGCGGATATGGCTGACTTAGTCGATGCTGAGTTGGACGAGGAGCAGGTGGCGTTAAAATGCCAGCCGGCAACTGATTACGATAGCAGTCAAGATAATATGAAAGATCATCACGTTAGGGTCAAAACCCCTCAGCTGCGGCGCAGTGCACGGCGAGCCAAACTGAGCACAGACAGCGAAAATGAGCCTTCCGAGCAGGTGAAGTCGTTGCCTGTTAAGCGTGGACGCGGTCGTCCCGTACGTCTGGCCAAGAGGGATACGACCACCAACGAGGACGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACATTCTCCTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTTTTGTGTGCGAGCACTGTGGCAAGAAGTTCCTGCGCAAGGACAAGTACATGACACATCTGCGATCGCACAAGAAGCACGTGtcaacaggcagacagacactgTCACGGAGCAACGAGTGGCGCTACGCGGAGCGTCTCTACAGCCCCGGCAGATTCTTGCGTGTGGAGTGCAAACTGTGCGGCTTGAGTTGCCAGCGCATTCGGGAGTTGCGCGAGCACCTGGCGAGTCATGATCACATTGAAACTTTGTCGAATCTGAGCCTGGACAACGATGTCATCCGAGAGCAGTTTGGCAGCCAATTGGATTTGCAGCAAATAAAGGAAAAGGTGTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACGGCGCCGTTGTGAATGCTTACGGCTATGAGCTGTGCCTCAGCGACtcggatgaggaggaggaaggGGAGCTGGCTGGCAAATATCAATGTCTGCGCTGCAATGTCAGCTTTACACGCAAGCATCAACTCATGGGTCACACGCTCGAGGAGCACACGGACAGAAGTGAGCCTCTTTTGGAACGCTGCAAAATCTGTCAAATTGGCTTTGTTTGCGTCAAGCTGCTGGAACAGCATCAGCGCACGCAGTGCCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAACATGCATGCTGCAAAGCGCAACCGGAtatgcagcatcagcattcggagcagcagcaggcacctCATCACCAGATCCAGTGTTGCCTGTGCGAAGTCCAACCTAGCAGCATGGCTGTCCTACGCTCTCATTTACTCACGCATCGTGATGGACACACCGGCATTGATCCGCAGCGGCAGTCTGCCTTCTTTCGTACCTATTACGACGATGACGGCGCCGGCTGCCTGTCGGAGCTCTGTGCACGCATCGCTGGCGATTTTGAGGCACAACTTTATGGAAGATATTTCAATGCGTGCACGGACAGCGGGCAGGAACTGGACTTCAACGACTCCGACAAGGAGTGGAGCGATGCGCCCGCTCTGCACAGCTGTGCCGTGTGTGGTGAGAGCAGAATCCGCCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATAGAGCTAGCGGGCAGCCTGCCTCATGTCTGCTCCGATTGTGGATTGGGCTATGTGGCCgagtcgctgctgcagcagcatcgtcGTCGCATCTGCGCCAAGCTGCATGCCAAGTACCAGTGTCCACATTGCAGTCAGCGCTTCTTTTGGCACTCCAACTACGAGCGGCACATTCAGGTGCAACATCCTACGGATAcgaagcaggagcaggagaagAGCAAGCTGCGGTGCAGCGAGTGCGATAAGGTGTTTATCTGGCCCAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGCGCCCACTGCGACCGCAAGTTTCATCGCAAGGATGGTCTTAAGTCGCACATGCGAATGCACGGTGAACAGCCGACGTCGTCTCTCGGTGAGCAGTTGCAGCGCATGCCGATGGTATTGAACCAGCTATGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCACCACACAAAAATCTCCGATTTACGAACTCATTTGACGAGCCATCAGTTGATGCTGTGTTTGGCCGAGGAGCGCGGCATCACAAATATTTCTCGTGCTCTTTATCCGGAGCTGAGCACGCCACTGGATCAGCAGGCATTGATCAAGCGCATCCAGCGTGATCTAACCAACGGCTTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGATTCGGATTGTGCAGCAGAAACCGAACGGAGTAGCACGGAACGCCGTTACAGCTGTGAATTGTGCCAGGTGCAGGTGATGCGGAAGCATCAGCTATATGCCCACCAGCTGGAGCAGCACACGTGGCACCAGACGACGCACGTGTGCAGCCACTGCCAGGCGAGATTCGTGAAtgagcagctgctggagcATCACTATCGCACCCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCATTGCGCTTTCGCTGGCGCGAAAATCTGAAGCTGCACAATGGTGTGGCGCATCAGGAGCGAGGGACTGTGGAACAGCACTCCAATGTGGACATTCAGTTGCGTATGCTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAgcttcaaaatgcaaaaggatCTCACACGGCACACTCTGATGCATGCCCAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCACGACGCTTCTATCGCGAGGCGAATCTGCTGCAGCACATCGAGCGACATGGCATCAGCGCCGACCAGCTGCCCTACGCGGAGGCCCTGCTCAACGCCAGCCGGCATCCGCATGGACTGAAGTGCATCCAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGTTCGCATCTGCAATCGTCGCCAATTGGCACTCACCATCCAATTGAGTCTATGGCCAACTATTCGATCACCAATCAGCTTGGCTACGAGCTGCACCTGGACGACTCCGAAACGGATGAAGAAGCCAAGCCGGCCGGCACTCCGGCACATTACACGTGCGGAATGTGCCAGCTGCGCTGTGTGCGCAAGTTTGaactgcatcagcatcagcaggccATGCATCGTCTGGAGCGCATCACCGATGGCTGCAATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCTGTTTAAGTGCTCTAAGTGCAGCTACAAGTTTATGTGGCAGTCGAATCTGGTGCAGCACATCAAACTGCAGCATCCCAGCAGCGAAGAGTCACCAACAAAACAGCAATGCCCAAGACCGTGCCCGACGTTGATAACGTCGATTGCCACATCTTCCAGTGTGTGTCATACAGCTGGCGCAACTGCATCAACAAAATTGCCATCGGTTACCAAGCAGCAGAAGAGTTTCCTATGCGCCTTCTGCGGCAAGGCGGTGAGCTCATCctccaatttaattatacacataCGTCGGCACACCGGCGAGAAGCCGTTCAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCCTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGCTTGTAAGAAGGGATTCGCTCGCTCATacaagctgcagcagcacatgCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGACGCCACACGGGCGAACGACCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGACAACAGAATGGCCACTACGAGACGGAAGTGGATCAATCGAAGGATGACTAA
Protein Sequence: MLPTNICRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVVQARQTQEQLLLQLRNGLQTQCLDETPIDISTEHIKIETDIDLDADMADLVDAELDEEQVALKCQPATDYDSSQDNMKDHHVRVKTPQLRRSARRAKLSTDSENEPSEQVKSLPVKRGRGRPVRLAKRDTTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGFVCEHCGKKFLRKDKYMTHLRSHKKHVSTGRQTLSRSNEWRYAERLYSPGRFLRVECKLCGLSCQRIRELREHLASHDHIETLSNLSLDNDVIREQFGSQLDLQQIKEKVCTQIAKGREQLENYGAVVNAYGYELCLSDSDEEEEGELAGKYQCLRCNVSFTRKHQLMGHTLEEHTDRSEPLLERCKICQIGFVCVKLLEQHQRTQCLNPLKRYSCENCPGKFIWLQNLQQHACCKAQPDMQHQHSEQQQAPHHQIQCCLCEVQPSSMAVLRSHLLTHRDGHTGIDPQRQSAFFRTYYDDDGAGCLSELCARIAGDFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPALHSCAVCGESRIRLDQLLQHQQSQHIELAGSLPHVCSDCGLGYVAESLLQQHRRRICAKLHAKYQCPHCSQRFFWHSNYERHIQVQHPTDTKQEQEKSKLRCSECDKVFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGEQPTSSLGEQLQRMPMVLNQLCRPNGCKQIKCMICLSHHTKISDLRTHLTSHQLMLCLAEERGITNISRALYPELSTPLDQQALIKRIQRDLTNGLELERFVSITNEAGIELSLDSSETDTDSDCAAETERSSTERRYSCELCQVQVMRKHQLYAHQLEQHTWHQTTHVCSHCQARFVNEQLLEHHYRTLCRNAQRRFLCRKCPLRFRWRENLKLHNGVAHQERGTVEQHSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGLKCIQCRVCELSFGSIAALRSHLQSSPIGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERITDGCNLCIFKSVSPDLIAYHRRVLCENTEKLFKCSKCSYKFMWQSNLVQHIKLQHPSSEESPTKQQCPRPCPTLITSIATSSSVCHTAGATASTKLPSVTKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTACKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRQQNGHYETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00583092; iTF_00514310;
80% Identity: -