Basic Information

Insect: Drosophila grimshawi
Gene Symbol: -
Assembly: GCA_018153295.1
Location: JAECXY010000311.1:4077966-4082699[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.00045 0.029 14.6 0.9 1 23 213 235 213 235 0.97

2 26 0.00032 0.021 15.0 4.1 1 23 241 263 241 263 0.98

3 26 0.017 1.1 9.6 0.7 2 23 296 317 295 317 0.96

4 26 0.0013 0.082 13.1 1.9 1 23 392 415 392 415 0.94

5 26 0.71 46 4.5 0.8 2 22 425 445 425 445 0.95

6 26 3.6 2.3e+02 2.3 0.4 1 19 454 472 454 474 0.91

7 26 8.5 5.5e+02 1.1 0.6 2 23 497 518 496 518 0.87

8 26 0.0039 0.25 11.6 0.5 1 23 592 615 592 615 0.96

9 26 0.0075 0.49 10.7 0.1 1 22 624 645 624 645 0.95

10 26 0.015 0.99 9.7 3.2 1 23 654 677 654 677 0.97

11 26 5.5e-05 0.0036 17.4 0.4 2 23 691 712 690 712 0.97

12 26 1.2e-05 0.00079 19.5 5.2 1 23 718 740 718 740 0.98

13 26 0.099 6.5 7.2 1.0 1 23 879 902 879 902 0.95

14 26 0.016 1 9.7 1.9 1 21 909 929 909 930 0.93

15 26 0.2 13 6.2 0.6 1 23 939 962 939 962 0.89

16 26 5e-05 0.0033 17.6 1.6 1 23 986 1008 986 1008 0.97

17 26 0.00038 0.025 14.8 0.7 1 23 1015 1037 1015 1037 0.98

18 26 0.11 7.2 7.0 0.0 2 21 1064 1083 1063 1084 0.94

19 26 0.033 2.2 8.7 4.0 1 23 1129 1152 1129 1152 0.96

20 26 0.0057 0.37 11.1 1.5 1 23 1189 1212 1189 1212 0.96

21 26 0.012 0.78 10.1 3.1 1 23 1239 1262 1239 1262 0.97

22 26 1.2e-05 0.00075 19.6 0.1 2 23 1284 1305 1283 1305 0.95

23 26 3.9e-05 0.0025 17.9 2.9 1 23 1311 1333 1311 1333 0.99

24 26 3.6e-06 0.00023 21.2 2.3 1 23 1339 1361 1339 1361 0.97

25 26 2.4e-07 1.6e-05 24.8 2.6 1 23 1367 1389 1367 1389 0.99

26 26 0.00044 0.028 14.6 0.4 1 22 1395 1416 1395 1419 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.00045	0.029	14.6	0.9	1	23	213	235	213	235	0.97
2	26	0.00032	0.021	15.0	4.1	1	23	241	263	241	263	0.98
3	26	0.017	1.1	9.6	0.7	2	23	296	317	295	317	0.96
4	26	0.0013	0.082	13.1	1.9	1	23	392	415	392	415	0.94
5	26	0.71	46	4.5	0.8	2	22	425	445	425	445	0.95
6	26	3.6	2.3e+02	2.3	0.4	1	19	454	472	454	474	0.91
7	26	8.5	5.5e+02	1.1	0.6	2	23	497	518	496	518	0.87
8	26	0.0039	0.25	11.6	0.5	1	23	592	615	592	615	0.96
9	26	0.0075	0.49	10.7	0.1	1	22	624	645	624	645	0.95
10	26	0.015	0.99	9.7	3.2	1	23	654	677	654	677	0.97
11	26	5.5e-05	0.0036	17.4	0.4	2	23	691	712	690	712	0.97
12	26	1.2e-05	0.00079	19.5	5.2	1	23	718	740	718	740	0.98
13	26	0.099	6.5	7.2	1.0	1	23	879	902	879	902	0.95
14	26	0.016	1	9.7	1.9	1	21	909	929	909	930	0.93
15	26	0.2	13	6.2	0.6	1	23	939	962	939	962	0.89
16	26	5e-05	0.0033	17.6	1.6	1	23	986	1008	986	1008	0.97
17	26	0.00038	0.025	14.8	0.7	1	23	1015	1037	1015	1037	0.98
18	26	0.11	7.2	7.0	0.0	2	21	1064	1083	1063	1084	0.94
19	26	0.033	2.2	8.7	4.0	1	23	1129	1152	1129	1152	0.96
20	26	0.0057	0.37	11.1	1.5	1	23	1189	1212	1189	1212	0.96
21	26	0.012	0.78	10.1	3.1	1	23	1239	1262	1239	1262	0.97
22	26	1.2e-05	0.00075	19.6	0.1	2	23	1284	1305	1283	1305	0.95
23	26	3.9e-05	0.0025	17.9	2.9	1	23	1311	1333	1311	1333	0.99
24	26	3.6e-06	0.00023	21.2	2.3	1	23	1339	1361	1339	1361	0.97
25	26	2.4e-07	1.6e-05	24.8	2.6	1	23	1367	1389	1367	1389	0.99
26	26	0.00044	0.028	14.6	0.4	1	22	1395	1416	1395	1419	0.91

Sequence Information

Coding Sequence: ATGTTGCCGACGAATATTTGTCGCACGTGTGCGTTGCAAGATGACAACTTGTTGGCATTGGCAACGCGGAGTGAAAAATACGCAAAGAAAAGTATTTGCGACATGCTGCACGAATTAACACAAAACGATCCTCTGCTGGAGCATACAGATGATAAGCTACCACAGCATTTGTGCGGCCAATGCTTGAGCCAGCTGGAAGCTGCCTATGCATTTGTGGTGCAGGTACGCCAGACGCAGGAGCAACTGTTGCTGCAGCTACGTAACGGATTGCAGACACAGTGCCTGGATGAAACACCCATCGATATAAGCACAGAGCACATCAAAATCGAAGCAGACATTGACCTAGATGCGGACATGGCTGACTTAGTCGATGCTAAGTTGGAGGAAGAGCAGGAGAAGCAGGTGGCCTTAAAATGTCAGCCGGCAACTGATAGCGATAGCAGTCAAGATAATGTGAAGGACCATCACATTAGGGTCAAAACCCCTCAGCTGCGGCGCAGTGCACGGCGAGCCAAACTGAGCACAGACAGCGAAAATGAGTCTTCCGAGCAGGTGAAGCCGTTGACTGTTAAGCGTGGACGCGGTCGTCCCGCACGTCTGGCCAAGAGGGAGACGACCACCAACGAGGACGGGCGGCATGTGTGCGAGGTGTGCGGCAAGACATTCTCCTGGTATCGCGACATGCAGCGCCATGCGCGCATCCACTTTGAGCAGGCGGGTTTTGTGTGCGAGCACTGCGGCAAGAAGTTCCTGCGCAAGGACAAGTACATGACGCATCTGCGATCGCACAAGAAGCACGTGTCAACAGACAGACAGACACTGCCACGGAGCAACGAGTGGCGCTACGCGGAGCGTCTTTACAGCCCCGGCAGATTCATGCGTGTGGAGTGCAAACTGTGCGGCTTGAGTTGCCAGCGCATTCGGGAGTTGCGCGAGCACCTGGCGAGTCATGTTCACATTGAGACATTGTCGAATCTCAGCCTGGACAACGATGTCATCCGAGAGCAGTTTGGCAGCCAATTAGATTTGCAGCAAATAAAGGAAAAGGTGTGCACGCAAATTGCCAAAGGTCGCGAGCAACTGGAGAATTACTGTGACGTTGTGAATGCTTACGGCTATGAGCAGTGCCTCAGCGATTCGGATGAGGAGGAGGAAGGGGAGCTGACTGGCAAATATCAATGTCTGCGCTGCAATGTCAGCTTTACACGGAAGCATCAACTCATGGGTCACACGCTCGAGGAGCACACGGACAGAAGTGAGACTCTTTTGGAACGCTGCAATATCTGTCAAATTGGCTTTGTTTGCGCCAAGCTGCTGGAACAGCATAAGCGCACGCAGTGTCTCAATCCGCTGAAGCGTTACAGCTGCGAGAATTGTCCTGGCAAGTTTATTTGGCTGCAGAATCTGCAGCAACATGCATGTTGCAGGGCGCAACCGGATATGCAGCATCGGCGTTCGGAGCAGCAGCAGGCACCTCATCACCAGATCCAATGTTGCCTGTGCAAAGTCCAACCCAGCAGCATGGCTGCCCTACGCTCTCATTTACTCACGCATCGTGATGGATATACCGGCATTGATCCGCAGCAGCAGTCTGCCTTCTTTCGCACCTATTACGATGATGACGGCGCCGGCTGCCTGTCGGAGCTCAGGGCACGCATCGCAGGCGATTTTGAGGCACAGCTTTATGGAAGATATTTCAATGCGTGCACGGACAGCGGACAGGAACTGGACTTCAACGACTCTGACAAGGAGTGGAGCGATGCGCCCATTCTGCACAGCTGTGCCGTGTGTGGCGAGAGCAGAATCCGTCTCGATCAGCTGCTCCAGCATCAGCAGAGCCAGCACATAGACCTAGCGGGCAGCCTGCCTCATGTCTGCTCCGATTGTGGATTGGGCTATGTGGCCGAGTCGCTGCTGCAACAGCATCGTCGTCGCATCTGCGCCAAGCTGCATGCCAAGTACGAGTGCCCACTTTGCAGTCACCGCTTCTATTGGCACTCCAACTACGAGCGGCACATTCAGGTGCAACATCCAACGGATACGAAGCAGGAGCAGGAGAAGAGCAAGCTGCAGTGCAGCGAGTGCGATAAGGTGTTTATCTGGCCCAAGGATTTGACGCGCCACAAGCGCATGCATCAGTCGCAGGTGCAGTTCGAATGCGCCCATTGCGATCGCAAGTTTCATCGCAAGGATGGCCTTAAGTCGCACATGCGGATGCACGGCGAGCAGCCGACGTCGTCTCTCGGTGAGCAGCTGCAGCGCATGCCGATGGTATTGAACCAGCTATGTCGCCCCAATGGCTGCAAGCAGATCAAGTGCATGATTTGCCTGTCGCAGCACACAAAGATCTCCGATTTGCGAACTCATTTGACGAGCCATCAGTTGACGCTGTGTTTGGCCGAGGAGCGAGGCATCGCAAATATTTGTCGTGCTCTTTATCCGGAGCTGAGCACGCCACTGAATCAGCAGGCATTGATCAAGCGCATCCAGCGTGATCTAACCAACGACTTGGAGCTGGAAAGATTCGTTTCGATAACCAACGAGGCGGGCATCGAACTAAGCCTGGACAGCAGCGAAACGGACACGGATTCGGATTATGCAGTAGAAACCGAACGGAGTAGCACGGAACGCCGTTACAGCTGTGAATTGTGCCAGGTGCAGGTGATGCGGAAGCATCAGCTATATGCCCACCAGCTGGAGCAGCACACGTGGCACCAGACGACGCACGTGTGCAGCCACTGCCAGGCGAGATTCGTGAATGAGCAGCTGCTGGAGCATCACTATAGCACCCTCTGCCGCAATGCCCAGCGGCGTTTCCTGTGTCGCAAGTGTCCATTGCGCTTTCGCTGGCGCGATAATCTGAAGCTGCACAATAGTGTGGCGCATCAGGAGCGGGGGACTGTGGAACAGGACTCCAATGTGGACATTCAGTTGCGTATGTTGCCCGTGGTTAGCTACGACTGTGTCGAGTGCAAGCGTAGCTTCAAAATGCAAAAGGATCTCACACGGCACACCCTGATGCATGCCAAGGAGTCGAGCATCTATCGGTGTCGCTGGTGCGCACGACGCTTCTATCGCGAGGCGAATCTGCTGCAGCACATCGAGCGACATGGCATCAGCGCTGACCAGCTGCCCTATGCGGAGGCCCTGCTCAACGCCAGCCGGCATCCGCATGGTCCGAAGTGCATCCAGTGTCGCGTGTGTGAATTATCCTTTGGCAGCATTGCGGCACTGCGTTCGCATCTGCAATCGTCGCCAGTTGGCACTCATCATCCGATTGAGTCTATGGCCAACTATTCGATCACCAATCAGCTTGGCTACGAGCTGCACCTGGACGACTCCGAAACGGATGAGGAAGCCAAGCCGGCCGGCACTCCGGCGCATTACACGTGCGGCATGTGCCAGCTGCGCTGTGTGCGCAAGTTTGAACTGCATCAGCATCAGCAGGCCATGCATCGTCTGGAGCGTATCGCCGACGGCTGCAATCTGTGCATCTTCAAGAGCGTCTCGCCCGATCTGATTGCCTATCATCGGCGTGTGCTGTGCGAGAACACGGAGAAGCAGTTTAAGTGCTCTAAGTGCAGCTACAAGTTTATGTGGCAGTCGAATCTGGTGCAGCACATCCAACTGCAGCATCCCAGCAGCGAAGAGTCGCCAACAAAAACAGCAATGCCCAAGACCGTGCCCGATATTGATAACGTTGAATGCCACATCTTCCAGTGTGGTCAGTGTCCCAGTAAATACAATCGTAAGGATCGCCTCACCGCCCATGTGAAAAAGTGTCACACAGCTGGCGCAACTGCGTTAACAAAATCGGCAAAAGCGGCTACCAAGCAGCAGAAGAGTTTTCTGTGCGCCTTCTGCGGCAAGGCGGTGAGCTCATCCTCCAATTTAATCATACACATACGTCGGCACACCGGCGAGAAGCCGTTCAAGTGTGATTACTGCGACATGGCCTTTCCGCGCTCTTCCGATCTCCAGTGCCATCGACGCACCCACACCGGCGAACGGCCCCACATCTGCACCGTCTGTAAGAAGGGATTCGCTCGCTCATACAAGCTGCAGCAGCACATGCGCATCCACAACGGCGAACGGCCCTACAAGTGCACCTTCTGCGACAAGAGCTTCACCCAGTCCAATGACCTCACCCTCCACATCCGACGCCACACGGGCGAACGACCTTATCAGTGCAATACTTGCGGCGAGCGATTCATTCAGGGCACAGCGCTCAAGAACCATCGACAGCAGAATGGCCACTACGAGACGGAAGTGGATCAATCGAAGGATGACTAA
Protein Sequence: MLPTNICRTCALQDDNLLALATRSEKYAKKSICDMLHELTQNDPLLEHTDDKLPQHLCGQCLSQLEAAYAFVVQVRQTQEQLLLQLRNGLQTQCLDETPIDISTEHIKIEADIDLDADMADLVDAKLEEEQEKQVALKCQPATDSDSSQDNVKDHHIRVKTPQLRRSARRAKLSTDSENESSEQVKPLTVKRGRGRPARLAKRETTTNEDGRHVCEVCGKTFSWYRDMQRHARIHFEQAGFVCEHCGKKFLRKDKYMTHLRSHKKHVSTDRQTLPRSNEWRYAERLYSPGRFMRVECKLCGLSCQRIRELREHLASHVHIETLSNLSLDNDVIREQFGSQLDLQQIKEKVCTQIAKGREQLENYCDVVNAYGYEQCLSDSDEEEEGELTGKYQCLRCNVSFTRKHQLMGHTLEEHTDRSETLLERCNICQIGFVCAKLLEQHKRTQCLNPLKRYSCENCPGKFIWLQNLQQHACCRAQPDMQHRRSEQQQAPHHQIQCCLCKVQPSSMAALRSHLLTHRDGYTGIDPQQQSAFFRTYYDDDGAGCLSELRARIAGDFEAQLYGRYFNACTDSGQELDFNDSDKEWSDAPILHSCAVCGESRIRLDQLLQHQQSQHIDLAGSLPHVCSDCGLGYVAESLLQQHRRRICAKLHAKYECPLCSHRFYWHSNYERHIQVQHPTDTKQEQEKSKLQCSECDKVFIWPKDLTRHKRMHQSQVQFECAHCDRKFHRKDGLKSHMRMHGEQPTSSLGEQLQRMPMVLNQLCRPNGCKQIKCMICLSQHTKISDLRTHLTSHQLTLCLAEERGIANICRALYPELSTPLNQQALIKRIQRDLTNDLELERFVSITNEAGIELSLDSSETDTDSDYAVETERSSTERRYSCELCQVQVMRKHQLYAHQLEQHTWHQTTHVCSHCQARFVNEQLLEHHYSTLCRNAQRRFLCRKCPLRFRWRDNLKLHNSVAHQERGTVEQDSNVDIQLRMLPVVSYDCVECKRSFKMQKDLTRHTLMHAKESSIYRCRWCARRFYREANLLQHIERHGISADQLPYAEALLNASRHPHGPKCIQCRVCELSFGSIAALRSHLQSSPVGTHHPIESMANYSITNQLGYELHLDDSETDEEAKPAGTPAHYTCGMCQLRCVRKFELHQHQQAMHRLERIADGCNLCIFKSVSPDLIAYHRRVLCENTEKQFKCSKCSYKFMWQSNLVQHIQLQHPSSEESPTKTAMPKTVPDIDNVECHIFQCGQCPSKYNRKDRLTAHVKKCHTAGATALTKSAKAATKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHICTVCKKGFARSYKLQQHMRIHNGERPYKCTFCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRQQNGHYETEVDQSKDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577186;
90% Identity: iTF_00517121;
80% Identity: -