Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000019.1:8820122-8840967[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 3.5 2.6e+02 2.6 0.4 3 21 464 482 463 486 0.91

2 14 0.15 11 6.9 0.5 2 23 508 530 507 530 0.92

3 14 0.042 3.1 8.6 0.6 1 23 547 570 547 570 0.96

4 14 0.73 54 4.7 0.1 1 21 575 595 575 599 0.89

5 14 0.013 1 10.2 0.3 2 23 649 671 648 671 0.91

6 14 0.5 37 5.2 1.5 1 21 676 696 676 697 0.92

7 14 1.3 95 3.9 0.2 2 23 716 737 715 737 0.91

8 14 0.014 1.1 10.1 2.7 2 23 750 770 749 770 0.96

9 14 0.0002 0.015 15.9 2.0 1 23 776 799 776 799 0.96

10 14 0.00064 0.047 14.3 0.0 1 23 822 844 822 844 0.97

11 14 0.0061 0.45 11.2 4.1 1 23 851 875 851 875 0.98

12 14 0.15 11 6.9 4.1 1 23 880 904 880 904 0.96

13 14 0.016 1.2 9.9 1.8 2 23 915 936 914 936 0.97

14 14 0.0025 0.19 12.5 6.6 1 20 942 961 942 963 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	3.5	2.6e+02	2.6	0.4	3	21	464	482	463	486	0.91
2	14	0.15	11	6.9	0.5	2	23	508	530	507	530	0.92
3	14	0.042	3.1	8.6	0.6	1	23	547	570	547	570	0.96
4	14	0.73	54	4.7	0.1	1	21	575	595	575	599	0.89
5	14	0.013	1	10.2	0.3	2	23	649	671	648	671	0.91
6	14	0.5	37	5.2	1.5	1	21	676	696	676	697	0.92
7	14	1.3	95	3.9	0.2	2	23	716	737	715	737	0.91
8	14	0.014	1.1	10.1	2.7	2	23	750	770	749	770	0.96
9	14	0.0002	0.015	15.9	2.0	1	23	776	799	776	799	0.96
10	14	0.00064	0.047	14.3	0.0	1	23	822	844	822	844	0.97
11	14	0.0061	0.45	11.2	4.1	1	23	851	875	851	875	0.98
12	14	0.15	11	6.9	4.1	1	23	880	904	880	904	0.96
13	14	0.016	1.2	9.9	1.8	2	23	915	936	914	936	0.97
14	14	0.0025	0.19	12.5	6.6	1	20	942	961	942	963	0.94

Sequence Information

Coding Sequence: ATGAACTCGCAATCGGATGATCTGGAGGATTTGCACATGTGCATAAAGTGCAACGAGACGATTGTGGGTCTACGCAAATACATTTATCACCGTAAGCAAAATTGTCAGAGAATTGTCGGAAATAATCGCAAAGAGAAGCAATTGgtggctacaacaacaacatcttcCACATCCACCGCCCATGAGACGCGTACAGCCATAACTCGCTCCAGCTTGGAGCAGAGCTATGATGGGTTTAACTTCTCCGAGCCGGAGGCACCGAGCAGTTACCTTCGCAAGACGACGGCCAGTCATGGCGGCAAGACGTCGAAAGCCCTAACTGAGGCATATGATCCAACCTACGAGCTGGGCGCCGATGTCTTCTTCTcctcgctgcagctgcagagcGTCTCAACGGGCGGCAAGACGGGCGCTCGACCTGAACGTGGCGCCAAAGAGGACCAGAGCTGGCATTCAGCCAGCCGGTGTTCCGATCCATTGCTGAAGGCGGTGCGGGAGCATGAAGAGCCCGTCTTCAAGCCGCTGAACTTTGCGCACTCGCCAGAGGCGAGCGAGGAcgaggaggatgaggaggagccCGATGACACTGAAGGCGATGAGGATGAAGCAGATAACGACCAGGACCCAGACTATGATCCCGATCCCGATGACGATTACGATGGGCGACGCCACTCGCCGCCGACTGTGCCTGCCACGCACACCGGCGGCAAGTGGAGGCCGGAGCACCGGCCGCAGCTGCGTCACACGCACCTGGAACGCATCTCGCCCAGCTGGGATGAGCCGCCCGACGACGCCCACGACCATCCGCCCGCCGAGCATACACACGGCAAATGGGTGCCGGGCAGCAAGCAGCTGGAGTATCGCGAAAACATTGATCTGACCAAGCTAAAGCAGCCGGACGCCAGCTATTGGTGCAACATCTGCTGTCGACAGCTGAAGACGCGTCTCATCTACGATCAGCATCTGCGCAGCAACTATCATAAGCGGCGTGCGGACACTGAGTGCCAATTGGAGCAGGCCAATCTGCAGTCCGTCAATCTGAAGGTCAACAAAAACTTTGCTCATCCGCCGGCTGCAGCGAAGGAGCAGAGGCGACGACGGCGTCGTCTGCTGCGCTGCGATCTCTGCCGCCACAGCATGGCACGCCATCTCATCGGCAAGCATCTGATCTCCCACTATCACTATCGACGCATGCAGCAGAAGACACAGCTGCCCAGCCAGACTGACTCCCTGCACGACATCCTGGAGCACATGGGCAGCATTGTGCGACAGGCGCCATTCCAATGCCTGCCCTGTCGATTCTATGCCAATACGGAGGAGACTTTTCTGGCTCATTGGCGCTCATCCGCTCATTTCGAGCTGACCAAGCAACTGGGGGGCAGCTTCTGGTGCAGCTACTGCCAGTTCGAGTGCGAGAGCAACGAGGGAATGTGGCAGCATCTCCTGGGCAATGCGCACATGGAGGTGCTGCATGCGATCAATCGATCGGTGCCCGTTTGCATTGCCCAGCGACGGCATCTGAGCTGCTCCGTGTGCAAGGCCCGCTTTCTGTACAACGCACAGCTGCGACGGCATTTCGCCTCGGagcatgtgggcgtggcggccACAGGCAGCGCCTCGGATGACTATCAGAGCCGCTTTCGCTGTGACATTTGCGGAGCTGCGGAAAAATCGCGAATAGCCTTGCAGCGACACGAGAGGCACAAACATCGTCTGAGCAAATATTATTGTGCCGTTTGTCAGTTGGAGTTCGAGACGCCGCTGGCAGCTCGCAAGCATCGCAGTCTCTTGTCACATAGACAAAATGCGACTGTGCGTCAGGAGGCTGAGCCACCGGAGGAGGGGGAGGAAGCTGAAATTGAGAATATGCTGCGCGAGGTGCTGGACGAGCCGCTGTCGGAGTCCGAGCAGCCCACAACCAGCACAAGGCGGGCCTCGGTTATCGAATGCGCGAATTGCCAGCAAAAGTTTGAGTCGTCCGAAGCACTGATTCAGCATCGCCACGCAGCCCATCCCACGGAGAATCATTGCTGTCTCAGTTGCGGCAGCAGCTTTCAGAATGCTCAGGCCCTGGGACGGCACACGCGCAGCTGTCAGCCCATCACCTCGATTCCCTCAACTCGCCAATCGGTCGCCAATTACTGGCCCTGCGATCAGTGCGGCTTCAGTGCACAATATGAATCGGATCTGCTCTATCATCGCTTCTTTCACCTGCGCGGCCCCAACATTGGCAAGGACGAGCTGCTCCAATGTCCGCGCTGCCCCAAACAATTCCGCAAGCACTCGCTGCGCCCCCATCTGCGCAACCACACGGACGAGCGGATCTTCGAGTGTGCCCAGTGCAAGTCCAGGTTCGCCAGGCGACACAATCTCAAGAGTCACATGGCCAGCATTCATGGCCAAGGGGCACGTCCAAAGAAAGCTCCcaaaacgacgacgacggcgatgCAACCCACGAAGAAATTTGAATGTGCCATTTGTGGCAAAATTTTGGCTAGAAaGCAATCACTTGTAGTGCACGAAATGATACATACCAAGGCGAAGCATCAATTCCAATGCACTCTCAAGGACTGCTCCTATTCGGGACGCACGCGTGAGTGCCTGAAAACCCATATGAAATCCCACGCCCAAGGCAAACACAAATGTGGACGCGAGAACTGCACATATGTGGGCAAAAGCGAGCTGCACCTGAAGCGTCACCTCAAAACGCATGCAAATGACCGAGACGGTGGCAAAAGGCTCAAGTGCGATCAGTGCGGGTTCAGGGCACAGATCAAGGCTCACCTGGATCGTCACATGCGCAAACATACTGGAGAGAAGCCCCACAAATGTCCCCACTGTAGCTACCGGTGTAGCAGCCAAGACAATCTGCGCAAACATTTTACAAGGACGAACATACATCCGGGCAAGTTCCTCTACGAGTGTTCCACCTGTAATACATTTAAGAGCAACAGCTTTAAGGACTATCTGAAACATTCGAGCACACATGAAGCGGAAGAAGATCTGCTAAAGTtataa
Protein Sequence: MNSQSDDLEDLHMCIKCNETIVGLRKYIYHRKQNCQRIVGNNRKEKQLVATTTTSSTSTAHETRTAITRSSLEQSYDGFNFSEPEAPSSYLRKTTASHGGKTSKALTEAYDPTYELGADVFFSSLQLQSVSTGGKTGARPERGAKEDQSWHSASRCSDPLLKAVREHEEPVFKPLNFAHSPEASEDEEDEEEPDDTEGDEDEADNDQDPDYDPDPDDDYDGRRHSPPTVPATHTGGKWRPEHRPQLRHTHLERISPSWDEPPDDAHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLKQPDASYWCNICCRQLKTRLIYDQHLRSNYHKRRADTECQLEQANLQSVNLKVNKNFAHPPAAAKEQRRRRRRLLRCDLCRHSMARHLIGKHLISHYHYRRMQQKTQLPSQTDSLHDILEHMGSIVRQAPFQCLPCRFYANTEETFLAHWRSSAHFELTKQLGGSFWCSYCQFECESNEGMWQHLLGNAHMEVLHAINRSVPVCIAQRRHLSCSVCKARFLYNAQLRRHFASEHVGVAATGSASDDYQSRFRCDICGAAEKSRIALQRHERHKHRLSKYYCAVCQLEFETPLAARKHRSLLSHRQNATVRQEAEPPEEGEEAEIENMLREVLDEPLSESEQPTTSTRRASVIECANCQQKFESSEALIQHRHAAHPTENHCCLSCGSSFQNAQALGRHTRSCQPITSIPSTRQSVANYWPCDQCGFSAQYESDLLYHRFFHLRGPNIGKDELLQCPRCPKQFRKHSLRPHLRNHTDERIFECAQCKSRFARRHNLKSHMASIHGQGARPKKAPKTTTTAMQPTKKFECAICGKILARKQSLVVHEMIHTKAKHQFQCTLKDCSYSGRTRECLKTHMKSHAQGKHKCGRENCTYVGKSELHLKRHLKTHANDRDGGKRLKCDQCGFRAQIKAHLDRHMRKHTGEKPHKCPHCSYRCSSQDNLRKHFTRTNIHPGKFLYECSTCNTFKSNSFKDYLKHSSTHEAEEDLLKL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00549908;
90% Identity: -
80% Identity: -