Basic Information

Insect: Drosophila hamatofila
Gene Symbol: -
Assembly: GCA_035045345.1
Location: JAWNPA010000020.1:18056810-18060705[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00044 0.033 14.8 0.1 1 23 161 184 161 184 0.96

2 14 0.00022 0.016 15.8 2.3 2 23 233 255 232 255 0.97

3 14 0.013 0.99 10.2 0.9 1 23 357 380 357 380 0.93

4 14 0.14 10 7.0 6.2 2 23 429 451 428 452 0.95

5 14 0.0035 0.26 12.0 0.5 1 23 516 539 516 539 0.88

6 14 2.2 1.6e+02 3.2 0.1 2 14 558 570 557 582 0.85

7 14 0.00074 0.055 14.1 3.3 2 23 590 612 590 612 0.96

8 14 0.0024 0.18 12.5 0.1 1 23 715 738 715 738 0.95

9 14 9e-05 0.0067 17.0 0.3 1 23 790 813 790 813 0.93

10 14 0.0012 0.092 13.4 2.2 2 23 863 885 862 885 0.97

11 14 0.0013 0.098 13.3 1.4 1 23 971 994 971 994 0.92

12 14 0.15 11 6.9 1.5 1 21 1046 1066 1046 1067 0.95

13 14 0.26 19 6.1 0.2 2 23 1110 1133 1109 1134 0.87

14 14 6.3 4.6e+02 1.8 2.3 1 23 1152 1176 1152 1176 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00044	0.033	14.8	0.1	1	23	161	184	161	184	0.96
2	14	0.00022	0.016	15.8	2.3	2	23	233	255	232	255	0.97
3	14	0.013	0.99	10.2	0.9	1	23	357	380	357	380	0.93
4	14	0.14	10	7.0	6.2	2	23	429	451	428	452	0.95
5	14	0.0035	0.26	12.0	0.5	1	23	516	539	516	539	0.88
6	14	2.2	1.6e+02	3.2	0.1	2	14	558	570	557	582	0.85
7	14	0.00074	0.055	14.1	3.3	2	23	590	612	590	612	0.96
8	14	0.0024	0.18	12.5	0.1	1	23	715	738	715	738	0.95
9	14	9e-05	0.0067	17.0	0.3	1	23	790	813	790	813	0.93
10	14	0.0012	0.092	13.4	2.2	2	23	863	885	862	885	0.97
11	14	0.0013	0.098	13.3	1.4	1	23	971	994	971	994	0.92
12	14	0.15	11	6.9	1.5	1	21	1046	1066	1046	1067	0.95
13	14	0.26	19	6.1	0.2	2	23	1110	1133	1109	1134	0.87
14	14	6.3	4.6e+02	1.8	2.3	1	23	1152	1176	1152	1176	0.85

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCAATGTTTTCAGCCGATTTCGATGAAGGTGGTGGTGAAGTGGAGGGCCATAATAATGGCAATACCGCACTCGCAGACGAATTTATGggagaagaggaggaggaagaacAGGAGGCTGAAGAGGATGAGGGCTCGGCCGACGACAGgggcagcaaacaaaaagggCACGAGCCTGATGACGATGCcatatttgattttgagcTAGAGCCTATTGTTAACATTGCGGAACCAGAACTGGAACAGTTGCCCAGACAAACAGCGGTCCCCCTGCAGCCCCCAATACCGACGGGTCCAGCTATCCGACCCCAGCACCGCCAGTCGTTGCCAGCCTCGTTTGGTTCTCAGCCGATGGTGGGTCGTGGTGGTGCAGGTACGCTATCCACACGGCCAACGACCTCACAGATCAATGCCACCGATGAGAACGGCGTGCCAATCAATTATGAACTGGGCGTTACTTATATATGCCCCGCCTGCGGCGCAGAGTATAGGCAGCAGGACATGTGGAAGCGTCATATGAACCAAATGCATCAGTACAATACCCGGCGAGGTCTCAATTTCGTGGCCATTGACAAGCTGTATCATCGGTGCCTGGAGTGCAACAAGCGCATCGCGATGCACAGCAGGGAGAATTTGTTGAAGCACAAGTTCACCCATTTGCCATTTAGGTGCACCAAGTGCCACATATGCAAGCGCGAGTACAAATACAGGCAGGACCTGATGGTACATCTGCGAATGGTGCACTGTGATGAAGTGGTGGCCATGATGCGTGGTGGCAAATTGAGTGCCGGACGCAAGACGCGTGTTAGGGAGCCGCGCATCGAGCAGCATCGCGAACATTACGGGCAGGTTCATGACGACGGTGGCATGGAGGTCAAGAATGAGCTGTTGGAAGCGGAAGGTAATGCGGAGCCAGCTCAAGAGTCCTATCATGACTTGGATGATGAGCACAGTCACAGTTCCAATCAAGCGATTAGAAAGAATCGTAACACTTCTGTGGGAGCCAATGGCAGCGGTGCAGCGGATATTTGCGAGgactatatacactatatgtGTCCGGACTGTGGCACCGATTGTGATACGCACGCCCAGTGGAGTCAGCACATTGAGTTTGTCCACGATTACGTCAGTCGAAGGGGGCTGAACTTTCGCTGCGTGGATATGCAAATGCAGTGCCTCGAGTGCAAGCAGTTTGTCATCCCGAACACCATTAAGACGCTGCGCGCACATAAGTTCAGCCACTTGCCACAACCGGAGTGGATGCGTTGCAAACTGTGCTATAAGGGCTTCACAGAGCATCATGAACTACTGACGCATCTTCTCAAACAGCATCATTTGGAAACCTTAATGCCTGAGAACGAGGAGGaggaacaacagcagccattGGTTATATCCAGTGTGGGCGATGAGTGTGAGGAGAATCCGGGCATTGCATGCGATGATGAAACTTCATTGCATTGGGACGATGTACCTCGTCGTGGTGGTCGCATTGGTAGCGATGATATGTATGAGCCGCATATTGATTATCTCTGTCCGCAGTGCGGCAGGGAATTCATAGAGAAGAAACATTGGCGCACCCATGTTGTCCAAGTGCACGGCATGAATGATCTGACTAAGTTGAATTTCGAGGTGATCAACGATCGTCAGTTGAAGTGCACCGAATGCGATAAGATCATAACAAATGCCTATGGCATACAGAATGCCCAGCAGCACAGGATAACACATTTACCCTACAAGGCGTACGCGAGATGCCGCAAATGCCACAAGTCCTATACGGATCGCAAGGGTCTTGTCAAACACTTGGCAACATACCATCGCGTGGGCTACGAGCCGCGCAAAGTGGTTGGAACAGGCACAGGTGTTGCACCACTGACGCCAAGCAAATCGCAGATGCCGCGCAAGCAAATCGTCACCGTGGCCAACGAGACCTATGAGATTATCTATTTGGATGAGGAGCAATCACCGCCTagtaacaataatataaatgaagagAATGATTTCGGCGAGCAAATGCAAGCGGACGATGATGACTATGCCGTAGGCAGCACCAGTGGCTTAATGGGTCGCCATCCGCAAGCacctactgctgttgctgcagcaccCAATCCAAATCCGAATCGTTATAAGTGCGTAGACTGCGGTTCGCTCTTTGCCACACAGATAGCACTAAAGACTCACATCAGCGAGGAACATGATTTTATGGACACGCAATACAGTGCCAAAAAGTTTGACAATGCTGAGCCCACGGAGGAGGCAACTGCGGTGCCTGTTGCCGTTTCAGCCACTGCATCTAGTACGCCTGTAAAGAACACCTCGGGCGCTTCCACCATAGAGCAGAACTATATATTCCTGTGCCCGTCGTGCGGCAAGGCCTACAAGACGCAGTTTGAGTGGCGCCGCCACATCAACGAGGAGCACAATTTCGACAAAcggcaatatttaaatatgcgcCAGCTGGACAAATATCGCTATCAGTGCACCCTTTGCAAGGATGTTGTGTGTAATTCAAAGCTGAAGGGCCTGCAGGATCATCATTTTCGTCATTTGCCTTACCGGCTGTATCTGAAGTGCTTGGTGTGCGGCACCTGCTACAATCACAAGCCCAACATCGCAGCGCATCTGCGCACGCGGCACAACATCTATGAGCGCGACTCCTCATCTTGGCGTGAGCTGCACCAGAAGACCCAGAATGGCAATGAACAGCACAAGCATAAGGATAGGGATGTGCAAGCCACGGCTGCCACCGGAACTACTTCTGTCTCACCTACACCCGGCACCAGTCGCACGCTCAAGCCACAGCCGGGCGTGCTGCCGACGAGACCCGCTGGACTCAACACATTGGAGGATAGTATATCGTATCACAATGCCGTGGATCTGGACTTTATCACCTATTATTGTCCCAAGTGCAATAAGAACTTTGACTCGCATGCCTTTTGGCGCAAACACATCGTGGAGGTACACAACTATAATAGTCGGCAAGGCCTGAACTTTCGCCAGATTGACAACCACCACTATCTGTGCCTGGAGTGCTATAAGCGTGTGACTGTGACGCATACTAAGGGCGCCATTGGGCAGCTACAGTCGCACAAGTTCCGGCATTTACCGTATCGCTCCTTCAAGTGCTTGACTTGCACCGGGGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCACTTGAACCGCGACACCAATCGCTGTGACAACAAGCCACTCAGTGGCCAGGAGAATGATGAGGATACCACGGATCAGCCGGAGAGACCAGCTACCATGCTCGCAAAGGAGACACTCGATGTCGCAACGTATCGCTTGATGTGTCCACAGTGCGGTGATGGGTTTACCACCAGCAGCAAAGCTCTGTGGCGAGAGCACATTAACATCCATCATGGTCTGGGGAAGCGGGAGATGCTGCACCTGCGCAAGCTGGGCGACGAACTGTACCGCTGCACAGACTGTGAAGAGCAGCTGCATACGAATCGTTTGcgagagctgcagcagcatcgcTTCCAGCATTTGCCCTATGCCGCATACATACGCTGCCAGCTATGCGAGCAGCAGTCAGCGGATGGAGTGGGTCATGGTGTAGCTGCTGCCGGATTACATAGTATGCGGGAACTGCAACAGCACATACGCAATGTACATCCGGATGTGGTGGAGCAGGACGATCAAATGGAAGCACTGCTGGAAGAGGAGGACAGTCAGCAGCCATCGGTTAGCGGAGAAGCAACAGACAGTGGACTATATATGCCCCTGCCGCCGCATTTGCTAGACGATGATGTGGAGGACATGGAATTCGAGGAACAGTATCTGCTAGGTTAA
Protein Sequence: MEGMDLWTSMFSADFDEGGGEVEGHNNGNTALADEFMGEEEEEEQEAEEDEGSADDRGSKQKGHEPDDDAIFDFELEPIVNIAEPELEQLPRQTAVPLQPPIPTGPAIRPQHRQSLPASFGSQPMVGRGGAGTLSTRPTTSQINATDENGVPINYELGVTYICPACGAEYRQQDMWKRHMNQMHQYNTRRGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPFRCTKCHICKREYKYRQDLMVHLRMVHCDEVVAMMRGGKLSAGRKTRVREPRIEQHREHYGQVHDDGGMEVKNELLEAEGNAEPAQESYHDLDDEHSHSSNQAIRKNRNTSVGANGSGAADICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFSHLPQPEWMRCKLCYKGFTEHHELLTHLLKQHHLETLMPENEEEEQQQPLVISSVGDECEENPGIACDDETSLHWDDVPRRGGRIGSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVQVHGMNDLTKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKVVGTGTGVAPLTPSKSQMPRKQIVTVANETYEIIYLDEEQSPPSNNNINEENDFGEQMQADDDDYAVGSTSGLMGRHPQAPTAVAAAPNPNPNRYKCVDCGSLFATQIALKTHISEEHDFMDTQYSAKKFDNAEPTEEATAVPVAVSATASSTPVKNTSGASTIEQNYIFLCPSCGKAYKTQFEWRRHINEEHNFDKRQYLNMRQLDKYRYQCTLCKDVVCNSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDSSSWRELHQKTQNGNEQHKHKDRDVQATAATGTTSVSPTPGTSRTLKPQPGVLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEVHNYNSRQGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCTGEFVRKQMFFKHLNRDTNRCDNKPLSGQENDEDTTDQPERPATMLAKETLDVATYRLMCPQCGDGFTTSSKALWREHINIHHGLGKREMLHLRKLGDELYRCTDCEEQLHTNRLRELQQHRFQHLPYAAYIRCQLCEQQSADGVGHGVAAAGLHSMRELQQHIRNVHPDVVEQDDQMEALLEEEDSQQPSVSGEATDSGLYMPLPPHLLDDDVEDMEFEEQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00532646;
90% Identity: iTF_00551845;
80% Identity: -