Basic Information

Insect: Drosophila gunungcola
Gene Symbol: -
Assembly: GCA_011057485.1
Location: WTSR01005050.1:2280149-2284070[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00012 0.011 16.1 1.2 1 23 164 187 164 187 0.96

2 15 0.0012 0.11 12.9 3.1 2 23 236 258 232 258 0.90

3 15 0.0051 0.48 10.9 0.8 1 23 352 375 352 375 0.93

4 15 0.042 3.9 8.0 3.5 2 23 424 446 423 447 0.93

5 15 0.00033 0.03 14.7 0.2 1 23 516 539 516 539 0.92

6 15 4.7 4.3e+02 1.6 0.1 2 14 558 570 557 582 0.83

7 15 0.00047 0.044 14.2 3.3 2 23 590 612 590 612 0.96

8 15 0.0041 0.38 11.2 0.1 1 20 707 726 707 728 0.95

9 15 0.00076 0.07 13.5 0.2 1 23 759 782 759 782 0.93

10 15 0.0016 0.15 12.4 1.5 2 23 832 854 831 854 0.95

11 15 0.013 1.2 9.7 1.8 1 23 949 972 949 972 0.91

12 15 0.02 1.9 9.0 1.2 1 21 1024 1044 1024 1045 0.95

13 15 0.55 51 4.5 0.3 3 23 1077 1100 1075 1100 0.87

14 15 2.7 2.5e+02 2.3 0.1 1 13 1118 1130 1118 1134 0.79

15 15 8.9 8.3e+02 0.7 3.1 10 23 1171 1184 1170 1185 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00012	0.011	16.1	1.2	1	23	164	187	164	187	0.96
2	15	0.0012	0.11	12.9	3.1	2	23	236	258	232	258	0.90
3	15	0.0051	0.48	10.9	0.8	1	23	352	375	352	375	0.93
4	15	0.042	3.9	8.0	3.5	2	23	424	446	423	447	0.93
5	15	0.00033	0.03	14.7	0.2	1	23	516	539	516	539	0.92
6	15	4.7	4.3e+02	1.6	0.1	2	14	558	570	557	582	0.83
7	15	0.00047	0.044	14.2	3.3	2	23	590	612	590	612	0.96
8	15	0.0041	0.38	11.2	0.1	1	20	707	726	707	728	0.95
9	15	0.00076	0.07	13.5	0.2	1	23	759	782	759	782	0.93
10	15	0.0016	0.15	12.4	1.5	2	23	832	854	831	854	0.95
11	15	0.013	1.2	9.7	1.8	1	23	949	972	949	972	0.91
12	15	0.02	1.9	9.0	1.2	1	21	1024	1044	1024	1045	0.95
13	15	0.55	51	4.5	0.3	3	23	1077	1100	1075	1100	0.87
14	15	2.7	2.5e+02	2.3	0.1	1	13	1118	1130	1118	1134	0.79
15	15	8.9	8.3e+02	0.7	3.1	10	23	1171	1184	1170	1185	0.85

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTGTGGACGTCGATGTTCTCCKCGGATTTCGAGGAGGGCGGGGAGGCGGAACTGGAGGACAGCGAGCAgtatggcaatggcaacggcaaTGACGACTTTCCGGGCGACTCGGAGATCCTGGAAGCAGGCGATGCCATTGATGACCTGCTGGATGGCGAAGAGGACGAccgggaggaggaggaggatacCTACGAGGGTGGCACCAAGGGACCAAAACAACCCGATCCCGACGACGATGCCCTCTTTGACTTCGACATGGAGCCCATTGTAAGCATATCGGAGTCACAGNCACCGGTTTTGGCTCCTGCAGGAGCAATGGGTGTCCAATTGCGTCCTCCCATGCAGCGACACTCGCAGTCCGGAACTATGGGTCGTCCCAGATTGGGACCGGGACTCTCAGTGCGGCCCACCACCTCGCAGATCAACGCCACGGATGAAAAYGGGGTGCCCATTAACTACGAGCTGGGCGTGGTCTAYATATGCCCCGCCTGCGGTGGTGAGTTCCGGCAACAGGACCACTGGAAGCGGCACATGAACCACATCCACAAATATAACACGCTGCGCGGCTTGAACTTCTCGCCGCTGGACAAGCTGTATCAGCGCTGCAGGGAGTGCAACAAGCGGATCGCCATGCACAGCCGCGAAAACTTGCTGAAGCACAAGTTTACCCACCTGCCTTTCAGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAGTACAGGCAAGATCTAATGGTGCACCTGCGCATGGTGCACTGCGACGAAGTGGTGGCCATGATGCGGGAGGGATACAATGCGGCTGGCCGAAAGACACGGGTGCGGGAGTCGCGCActgagcagctgcagcgggAGAAGAGCTTTCGCGGGGATAGTGACTTCGTGGATGACTCTGATCGCATAGAGGTGCGGAATGAGCTGCTCGAGCCGGATGCCGATGAGTCTGGNNNNGTGGAGCAGTCATNNNCCGATGAGGTTACCAAGAAAAAGTCTCCTGGCAGTCGAGGAGCAGCCGAGCTCTGCGAGGATTACATCCACTACATGTGCCCCGATTGCGGCACCGAGTGCGACACCCACGCCCAGTGGAGCCAGCACATCGAGTTCGTCCACGACTATGTCAGCCGGCGGGGACTTAATTTCCGGAGCGTAGACATGCAGATGCAGTGCCTCGAGTGCAAGAAGATTGTGACCCCCAACACCATCAAATCGCTGCGCGCCCACAAATTCAGCCATTTATCGCAGCCAGAGTggctgcgttgcaaactttgcTACAAGGGATTCAAGGACCATCAAGAAGTGGTGAGGcatctgctgcagcagcaccatATGGATACGCTGATGTCAGAGGACgccgaagaggaggaggacgcTCCCAACGCCATGATGATGAATGAGGATGAATGCTTCGAGGACAATGGAAACGGCGAAGGAAACGGCGCCGTCTTGGACGAGGATTCTCCCTATTTTGAAGACGCACCGAGACGTGGCNGTCGCATCAGCAGCGATGACATCTACGAGCCTCACATCGACTACCTCTGTCCGCAGTGCGGCAAGGAGTTCATCGAGAAGAAACACTGGCGCGCCCACGTCGTTATGGCGCACAACATGAACGATCTGTCCAAGCTGAACTTCGAGATGATCAACGAGCGGCAGCTGAAGTGCACGGAGTGCGAGAAGATCATCACGAATGCTTATGGCATCCAGAATGCCCAGCAGCACAGGATCACTCATCTGCCGTTCAAGGCGTATGCCAGGTGCCGCAAGTGCCACAAGTCCTACACGGACAGGAAGGGTCTTGTGAAGCATTTGGCTACCTATCATCGCGTTGGTTGTGGGCCACGAAAGTCCGCGGGCGGAGTTGGCGGCCCTGCTCTGATGCCCACTCCCACCAAGCCACCTCGCAAGCAGATCGTCACGATCGCCAATGAAACGTACGAGATAATCTACTTGGACGACGTGGAGCAGGGCGGCGGCATGGAGGAGGACAACGACTTTGGCGAACAAATGCAGGCGGATGAGGAGGATTACCCTGTTGCGCCAcccgcaccaccaccaccgccgccggcNNNNNNGCCGTCNNNGTCGCAGGGCAACCATCATCGCTACAAATGCGTCCACTGCGGCACACTCTTCCCCACCCAGGCGGCCGTGCGGGTTCACATAAGCGAGAAGCGCTGCCGGAAGACAGTGGGCAGGAGGCATAGGCAGGCAACGGCCAACGCGGACCCATCCATTCCCACCGTGGAACAAAACTACATTTTCCTCTGTCCCTCTTGCGGCATGGAGTACAAGACGCAGTTCGAGTGGCGGCGCCACATCAACGAGGTTCACAACTTCGACAAGCGGCAGTATCTTAACATGCGGCAATTGGACAAATATCGCTACCAGTGCACCCAGTGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGCTTGCAGGACCACCACTTCCGCCACCTGCCCTACCGACTGTACCTCAAGTGCCTGATCTGCGGCACCTGCTACAATCACAAGCCGAACATAGCGGCGCATTTGAGGGCCCGCCACAGCATCTTCGACAGGGAGACGCCGGTGATGGTCACCAANCCGAAGCATGTGCTTGGCCGCTACAAGGACGGCAGTAGGGAAAAGCACAGAGTGCCATCTCCCACGCCGCTGCCAGCGCCCTCTCCACCCGGATGCTCCTNCTCGGCAGCCTCGGCAGCCTCCTCTGCGATCGTTCGCTCTCTTAAGCCGCAACCCGGCGGCCTGCCCACTCGACCCGCTGGTCTCAACACCCTGGAGGATAGCATCTCGTACCACAATGCCGTGGACTTGGACTTCATCACATACTTCTGCCCCAAGTGTAACCAGAACTTTGACTCGCACGCCTTCTGGCGTAAGCACATCGTGGAGCAGCACAACTTCAACAGCCGCGAGGGTCTCAACTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGGGTGACCGTGACCCACACCAAGGGCGCCATAGGTCAGCTGCAGTCGCACAAGTTCCGCCATCTGCCGCACCGATCCTTCAAGTGTTTAACCTGCGACGGCGAGTTTGTGCGCAAGCAAATGTTCTTTAAGCACCTCAATCGCGACACCAATCGGTGTGACAATCGCCCGCACCGGGACTTGGAAGAGGAGGAGCCGGATCAGGAGACGCAGCTACGCTCCATCTACCACATGGCTTGCCCGCAGTGCGGCGACAACTTTACAACCCGCAACAAGAAGCAGTGGCGCGAGCACATCAACGACTACCACGGTCTGGCCAAACTGGACCTGTTGCACATGAGCAAAGTGGGCGAGGACCTCTTCCGCTGCCAGGACTGTGACGAGGAGCTGCAGACGAAGCGACAGTGGGTGCTGCAGTTCCACCGTTTCCAGCACCTGCCCCACGCGGCCTACATCCGTTGCAAACTCTGTAAGCAGAGCGGCGAGGCGGGTTCNGCAGAATCAGTAGCGGCAAGCGGTTTTCACAGCCTCCGTGAGCTGCAACAGCACCTCCGAAAGCACCATCCAACAGTGGGCGAAAGCGAGATGATATTGCTTCGCGAGCAGATCGTCCtggaggagaaggagcaggAAGACGCAACGGATCTGCCCGCAGACGAAGACAATCAGGCTGGCCAGGATTCGGGACCGTAtatgccgctgccgccgcatTTATTGGACGATGGGGACGAATTCGAGGACCATTATCTTCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSXDFEEGGEAELEDSEQYGNGNGNDDFPGDSEILEAGDAIDDLLDGEEDDREEEEDTYEGGTKGPKQPDPDDDALFDFDMEPIVSISESQXPVLAPAGAMGVQLRPPMQRHSQSGTMGRPRLGPGLSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFSPLDKLYQRCRECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLQREKSFRGDSDFVDDSDRIEVRNELLEPDADESGXVEQSXXDEVTKKKSPGSRGAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKSLRAHKFSHLSQPEWLRCKLCYKGFKDHQEVVRHLLQQHHMDTLMSEDAEEEEDAPNAMMMNEDECFEDNGNGEGNGAVLDEDSPYFEDAPRRGXRISSDDIYEPHIDYLCPQCGKEFIEKKHWRAHVVMAHNMNDLSKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATYHRVGCGPRKSAGGVGGPALMPTPTKPPRKQIVTIANETYEIIYLDDVEQGGGMEEDNDFGEQMQADEEDYPVAPPAPPPPPPAXXPSXSQGNHHRYKCVHCGTLFPTQAAVRVHISEKRCRKTVGRRHRQATANADPSIPTVEQNYIFLCPSCGMEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIFDRETPVMVTXPKHVLGRYKDGSREKHRVPSPTPLPAPSPPGCSXSAASAASSAIVRSLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPHRDLEEEEPDQETQLRSIYHMACPQCGDNFTTRNKKQWREHINDYHGLAKLDLLHMSKVGEDLFRCQDCDEELQTKRQWVLQFHRFQHLPHAAYIRCKLCKQSGEAGSAESVAASGFHSLRELQQHLRKHHPTVGESEMILLREQIVLEEKEQEDATDLPADEDNQAGQDSGPYMPLPPHLLDDGDEFEDHYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486896;
90% Identity: -
80% Identity: -