Basic Information

Insect: Drosophila guanche
Gene Symbol: -
Assembly: GCA_900245975.1
Location: NW:1894286-1897501[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 3e-07 1.8e-05 24.5 0.9 1 23 213 236 213 236 0.96

2 17 0.015 0.89 9.7 0.4 1 23 243 265 243 265 0.98

3 17 0.19 11 6.3 0.1 2 23 297 318 296 318 0.94

4 17 3.7e-05 0.0022 17.9 3.1 1 23 407 430 407 430 0.97

5 17 0.23 14 6.0 0.5 1 19 437 455 437 458 0.94

6 17 0.022 1.3 9.2 5.2 1 23 467 489 467 489 0.95

7 17 1.8e-05 0.0011 18.9 0.7 1 23 496 519 496 519 0.97

8 17 0.00036 0.021 14.8 2.6 2 23 527 548 526 548 0.96

9 17 0.013 0.74 10.0 0.0 2 21 575 594 574 595 0.94

10 17 0.0039 0.23 11.5 2.7 1 23 645 668 645 668 0.98

11 17 0.25 15 5.9 1.9 1 23 705 728 705 728 0.92

12 17 0.00011 0.0066 16.4 1.6 2 23 757 779 756 779 0.95

13 17 9.9e-05 0.0058 16.6 0.2 1 23 793 815 793 815 0.95

14 17 0.00012 0.0068 16.4 1.1 1 23 821 843 821 843 0.99

15 17 2.9e-07 1.7e-05 24.5 2.3 1 23 849 871 849 871 0.98

16 17 3.2e-05 0.0019 18.1 3.8 1 23 877 899 877 899 0.97

17 17 0.00041 0.024 14.6 0.4 1 22 905 926 905 929 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	3e-07	1.8e-05	24.5	0.9	1	23	213	236	213	236	0.96
2	17	0.015	0.89	9.7	0.4	1	23	243	265	243	265	0.98
3	17	0.19	11	6.3	0.1	2	23	297	318	296	318	0.94
4	17	3.7e-05	0.0022	17.9	3.1	1	23	407	430	407	430	0.97
5	17	0.23	14	6.0	0.5	1	19	437	455	437	458	0.94
6	17	0.022	1.3	9.2	5.2	1	23	467	489	467	489	0.95
7	17	1.8e-05	0.0011	18.9	0.7	1	23	496	519	496	519	0.97
8	17	0.00036	0.021	14.8	2.6	2	23	527	548	526	548	0.96
9	17	0.013	0.74	10.0	0.0	2	21	575	594	574	595	0.94
10	17	0.0039	0.23	11.5	2.7	1	23	645	668	645	668	0.98
11	17	0.25	15	5.9	1.9	1	23	705	728	705	728	0.92
12	17	0.00011	0.0066	16.4	1.6	2	23	757	779	756	779	0.95
13	17	9.9e-05	0.0058	16.6	0.2	1	23	793	815	793	815	0.95
14	17	0.00012	0.0068	16.4	1.1	1	23	821	843	821	843	0.99
15	17	2.9e-07	1.7e-05	24.5	2.3	1	23	849	871	849	871	0.98
16	17	3.2e-05	0.0019	18.1	3.8	1	23	877	899	877	899	0.97
17	17	0.00041	0.024	14.6	0.4	1	22	905	926	905	929	0.90

Sequence Information

Coding Sequence: ATGAAGCTGCCGGGTATTTGTCGGACCTGTGATGCGACAGATGCCGATAATCTCTTGAAGCTGGCCACTCCCACTAAGAAGTACCCAGACAAGTTGCTTTCGGACATCTTGAgcgaattaattaattttaatCTGGATACATCTAACCAGAAGCTTCCACAACGGTTGTGCAGCAGTTGCACCAAGAAATTAATGGGTGCCTATTGCTATATGAGACAGGCGCTGGACGCCAATGAAATATTGCTGAGGCACCTGAAAAACGGTACTACCGACTGCTTGCAAGAAACGCCAATGGAACTTTGTGCGGAGCAACATGTGATGGTGAAACTAGAAACGGATGATGAGGATGGAAGGGGGACtgaaacaaacataaattgcTCTGGCTTACCTGAAATTGTCCCAGAAGAGATTCCAGACGAGAAAGATTTCGACCACAAGAAATCTGTTGATCCCCTAATAATGATCGATTCTGTTAAGCAGGAAACTGTCCAGGCCAGGATAGAAAAGCATGTGGGCGACGAAGCCGGGTCGGACTTTGAGGACGAAGACTCGCTGGATAACTTACCGCTGGGACAGCGCATACTTAAATGGAAGACGGGAAGTGTCGATTCCTTGCGAAGCCTGAATCGGTCGGCATATCAGTGCAATGAATGCCCAAAGAGCTACAAAAGAGCCGATTATCTGAAACGACATCAGGTCAAAGCTCATAGGCCAGAATCCCGTTGGTTCTCCTGCTCACTCTGCATCCGAAAGTTCAATAGCAGTGAAGCCTTAGATATGCATCTCAAAGTACATCGAAACTCCAAGCGTTCGGCCAATATAAGTGAACTTAAAAAGGCAAAGTCTGTGGATCTAAATCTTTGCAAACCCCATGGCTACAAGCTCATCGAATGCATGATATGTCAGAGTCAGTATAACAAGATTGCGGACTTGCGACGCCATTTGGAGGAGCATCCGGCAATTGTTACCTTGGGTGTGCGTCCAAATATGGAGCCCAATGAGTTGGCCGAATTGTTCTATCCCGATGCCAAGGATGTTGGCGAGGATCAATTAATTGAGTTAATTCGCAAAGATTTGGCAGGCGGCATTTATCATCGCTTCTATTCCATAACTAATCAGTGTGGTTATGAAATGAACCTGGACAGCTCTGACACTGATAGTGAGCTGGACGTGGAGCCCGAGGACCAACTAAAGAAGCGCAAAACTAGACACGCGCACTACAGCTGCGAGCTGTGCCAACAGAGGTTTACCAGGAAGTATCAACTCTACGATCATCAGCGTCAGACGCACAGCTGGTCCGAAGCACCGCATGTTTGCGGCCGTTGCGATGGCCGCTTTGTCAGTTTGCAAATGCTGAGGCATCATAATGAGTCGCAGTGCAGAAACTCGCAAAAGCGATTCCTTTGCCATAAATGCCCACTGCGTTTCCGGTGGAAGCACAACCTGAGAGCACACTTCCGAGAGCACCGAATCACGAATCAAACCTTCGAATGTTCCGAATGCAAGCGAGTTTTTGATAAGAAAAAATCACTGACTGTTCATTTACTCAGCGCTCATGCTGAGGAATCTAAACTCATTCCGTGTCAGTGGTGTACGCGCAAGTTCTACCGTCATGATTACCTGGTGAAACATCTAAAGCGGCACGGACTCAAGGAGCAGGACATTCCATTGGCCGAGACTTTGATAGCTGCCACATCGAAGCGAAATGGAGCCAAGCGCATTAGCTGTAAAATTTGCAACCTGGACTTCGACCGCATCATAGACTTGCGAGCCCACATTCAACTGGAACTAAAGCTTTCTCTCAACTCTCAGCACCATAGCTATGACTCCCCACAAAACTACTCTATAACCAATGAATCCGGGTTCGAGATGCAGCTTGAAGATTCGGAAACAGAGGACGAAATACAGCCCGGGTCTCTCATCCGTCCTCCCTACGTCTGCGAGCTTTGCAGTGTCCAGTGCAAGCGCAAATTCGAAATGATTCAACATCAACGAACCATGCACCGCTTCGACAAAATGCCTCATGAGTGTGATAAGTGCGTTTTCAAGTGTGTGTCCAAGAATATTATGGATCATCATCTTCTATGGcaatgcagcagcacagaGAAGAAGTATTCATGCAGCAAGTGCACCTATAAATTCATGTGGCCTGAGAATCTGGATAAACATGTGCACCTCCAGCACAGCGAAGTCTCTGAAAGTACCAAAGCAGCCAAGCCGACAAGTGGTCTTGTCGACGAAGCCACAGAGGACGGAGTCCAGCTGCTGCAATGCCCGCATTGTGATCGCACCTATCAAATGAAGTCGCGATTGAACAACCACATTCGAGATGTTCATGTAAACGGCGATCGGAAGCGCAAGGATGCGATTAAGCGATTCCTTTGCTCGCTTTGTGGCAGAGAAACgcggtctgctgctgctctggttACCCACATGCGACGCCACACCGGCGAGAAGCCCTTTAAATGTGATCTATGTGAAATGGCTTTTCCGAGACACTCGGAGATGGCTTCGCATCGCAGGATGCATACGGGGGAGAAACCATTCCACTGCACAGTTTGTGGCAAGGATTTTGCCCGGTCCGACAAACTGACGCGCCACATGCTCACCCACAGCGGACTGAAGCCGCATAAGTGCACGTACTGCGAGAAGAGCTACCGGCAAGCCAAAGATCTTAAGctccacttgcagcagcacacaggCGAGTGTCCATTTATCTGTGGTACTTGTGGCGAACGTTTTATTCAAAACATAACTCTGGAGAAGCATCGTCTAATGCGCCGCCATTTCGATTGGAGCTTgccataa
Protein Sequence: MKLPGICRTCDATDADNLLKLATPTKKYPDKLLSDILSELINFNLDTSNQKLPQRLCSSCTKKLMGAYCYMRQALDANEILLRHLKNGTTDCLQETPMELCAEQHVMVKLETDDEDGRGTETNINCSGLPEIVPEEIPDEKDFDHKKSVDPLIMIDSVKQETVQARIEKHVGDEAGSDFEDEDSLDNLPLGQRILKWKTGSVDSLRSLNRSAYQCNECPKSYKRADYLKRHQVKAHRPESRWFSCSLCIRKFNSSEALDMHLKVHRNSKRSANISELKKAKSVDLNLCKPHGYKLIECMICQSQYNKIADLRRHLEEHPAIVTLGVRPNMEPNELAELFYPDAKDVGEDQLIELIRKDLAGGIYHRFYSITNQCGYEMNLDSSDTDSELDVEPEDQLKKRKTRHAHYSCELCQQRFTRKYQLYDHQRQTHSWSEAPHVCGRCDGRFVSLQMLRHHNESQCRNSQKRFLCHKCPLRFRWKHNLRAHFREHRITNQTFECSECKRVFDKKKSLTVHLLSAHAEESKLIPCQWCTRKFYRHDYLVKHLKRHGLKEQDIPLAETLIAATSKRNGAKRISCKICNLDFDRIIDLRAHIQLELKLSLNSQHHSYDSPQNYSITNESGFEMQLEDSETEDEIQPGSLIRPPYVCELCSVQCKRKFEMIQHQRTMHRFDKMPHECDKCVFKCVSKNIMDHHLLWQCSSTEKKYSCSKCTYKFMWPENLDKHVHLQHSEVSESTKAAKPTSGLVDEATEDGVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKDAIKRFLCSLCGRETRSAAALVTHMRRHTGEKPFKCDLCEMAFPRHSEMASHRRMHTGEKPFHCTVCGKDFARSDKLTRHMLTHSGLKPHKCTYCEKSYRQAKDLKLHLQQHTGECPFICGTCGERFIQNITLEKHRLMRRHFDWSLP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487433;
90% Identity: iTF_00611484;
80% Identity: -