Basic Information

Insect: Drosophila grimshawi
Gene Symbol: prg
Assembly: GCA_018153295.1
Location: JAECXY010001376.1:15391238-15394629[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.2 13 6.2 1.1 1 19 217 235 217 240 0.85

2 9 0.001 0.068 13.4 0.1 1 23 246 269 246 269 0.96

3 9 4.5e-06 0.00029 20.9 0.3 1 23 275 297 275 297 0.97

4 9 9.3e-08 6.1e-06 26.1 4.3 1 23 303 325 303 325 0.98

5 9 2.4e-05 0.0016 18.5 0.6 1 23 331 353 331 353 0.98

6 9 2.2e-05 0.0014 18.7 0.7 1 23 359 381 359 381 0.98

7 9 2.8e-05 0.0018 18.3 0.5 1 23 455 477 455 477 0.96

8 9 1.7e-05 0.0011 19.0 0.2 1 23 482 505 482 505 0.91

9 9 0.037 2.4 8.5 0.6 1 23 509 531 509 531 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.2	13	6.2	1.1	1	19	217	235	217	240	0.85
2	9	0.001	0.068	13.4	0.1	1	23	246	269	246	269	0.96
3	9	4.5e-06	0.00029	20.9	0.3	1	23	275	297	275	297	0.97
4	9	9.3e-08	6.1e-06	26.1	4.3	1	23	303	325	303	325	0.98
5	9	2.4e-05	0.0016	18.5	0.6	1	23	331	353	331	353	0.98
6	9	2.2e-05	0.0014	18.7	0.7	1	23	359	381	359	381	0.98
7	9	2.8e-05	0.0018	18.3	0.5	1	23	455	477	455	477	0.96
8	9	1.7e-05	0.0011	19.0	0.2	1	23	482	505	482	505	0.91
9	9	0.037	2.4	8.5	0.6	1	23	509	531	509	531	0.98

Sequence Information

Coding Sequence: ATGAAAGGACACAGGGTAGTTCATGATGATGACACGCACACATGTCGCTTGTGCCACTCACGGATAAAATCGACCACAGATTCGCCGAATATTTACGAGGCGTCTGTTGACTTTGGCCACGAGGAAGAAGAAGAAGGAAGAACAGAAGAGGAAAAAGTCATAATTGCCGATGTTTGCCAGACTGTTTATGGTGTGAAATATGAGCGCCATGAGTTCCTGCCGGAGCACATTTGTATGAACTGCCTGGAGATATTGAGGGACTTCTACGAGCAACGCCAATACATGCAGCAGCATGAATTGGAGCTGCAGCAGAACCTAAAGAAAATAATTGCTGTGGATGCCAAGTATCGACCCGGCCTCAACGGCAATCCTGGCGAGTTTGCATTCGGGGACGGCGAAGAAGGCTGCGTCATTGTCGATGTGGATCCCGAGCAACTGTGCGAAACGAGTGATGACGAATTCCCAGGCTCCGAAGGTGAAGCTGAACTCGATGACGAGGATTGGGACGACGAGGATGAGGAAGGAGGAACTGCACAAAATGAAGAAACAGAGATGCCTCTCGGCATGGATGCCGCCCAAATGGCGATGATGCGGGTGCATCAAACGGTCGACTCCAGTGTCCAATTCAATGCGCATCCAAAGAGCGCCTTCCTCTGCCAGTACTGCGATCTGGCCTTCACCCTACAGTCGGACTGCCAGCAGCATGAAGTGGGCTCTCACGACGCCTCGGCGCCGTACATTTGCAACTACTGTCAGGTGAGATTGACGACACGTCCGGCATTAATTGCGCACATCAAGGAGCTGCATGATGCCGAGCGTCCCTATGTGTGCGCACTGTGCAGCAAGGGATTCGTGCGACGTTCGGACTTGAAGAAGCACACAATTGTGCATACGGGCGTGCGTCCGTTCTCGTGCCACGTCTGCTCTAAGAGCTTCTCGCGCAACACCAACCTGACCAAGCACCTGCGCATCCACAGCAGCGTGAAGCCGTTCGTTTGCCAGCAGTGTCCACGCTCATTCCAGACACCGCTGGAGCTGCTGAAGCACACGCGCTCCCATGCCGAAGTGAAACCATTCCGGTGCGGTCGCTGCCCCGCCTCGTTCACCCGCAAGGACAAGCTATTGATGCATCAGCAGGTGCATCTGAAGCGCGACATCGAGCAAAAGCAAAGTCAAAACCTGCGCATAAATATGATTATGCCGGCAGAGCAGATGCAAGTGCAGCTGCCACTCCATCCGTACGTGGAGCCAGATGCATCGGCCCAACAGGCCTTACCGGCTATACCAGCATATCCGTTTCAGCAGCAAACGCCTCCCGTGATGCAGCCTAAGGTGAAACCATCTCCGAAGGTAACGCGCAATTTCCGCTGCGATGTATGCGATCGGGGCTTCCAACGGGAGCGGGATCTGCAGCGCCATCGGGCCCTGCACATGGACACACTATTCGCCTGCAAGTTGTGCGGCCAGGGCTTTAATCGGCGTGAGCAACTGCAGCGTCACGAGCTGGAGGCTCATGGCCCCAGCTATACATGTGCCATTTGCTGCATCACTTTCCTGCAACAGGCGGAGCTGGAGACGCATCTCAAAGTGCACGAGCTGCAGCACAGTGTGGCCAAAAGCAACCAGGAGGCTTTAATAGCTGCCGCCGCTGTAGTACCGCTAGCTAATCCCATGGGCGAGCACACGGGTGCCCCAATGCCAGCCATCGTTCCAGAGCCCGTCCAGCTGCCCAATGTACGGCCTTCCGCAGCCGAAATGTCCTTCTATAGCAACATGATACCTACCATGAATCTGGGCTTCTACAGCGAGACGCGTCCCGAAGAGCGCAACGGAGTTTAA
Protein Sequence: MKGHRVVHDDDTHTCRLCHSRIKSTTDSPNIYEASVDFGHEEEEEGRTEEEKVIIADVCQTVYGVKYERHEFLPEHICMNCLEILRDFYEQRQYMQQHELELQQNLKKIIAVDAKYRPGLNGNPGEFAFGDGEEGCVIVDVDPEQLCETSDDEFPGSEGEAELDDEDWDDEDEEGGTAQNEETEMPLGMDAAQMAMMRVHQTVDSSVQFNAHPKSAFLCQYCDLAFTLQSDCQQHEVGSHDASAPYICNYCQVRLTTRPALIAHIKELHDAERPYVCALCSKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTPLELLKHTRSHAEVKPFRCGRCPASFTRKDKLLMHQQVHLKRDIEQKQSQNLRINMIMPAEQMQVQLPLHPYVEPDASAQQALPAIPAYPFQQQTPPVMQPKVKPSPKVTRNFRCDVCDRGFQRERDLQRHRALHMDTLFACKLCGQGFNRREQLQRHELEAHGPSYTCAICCITFLQQAELETHLKVHELQHSVAKSNQEALIAAAAVVPLANPMGEHTGAPMPAIVPEPVQLPNVRPSAAEMSFYSNMIPTMNLGFYSETRPEERNGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00511438;
90% Identity: iTF_00610063;
80% Identity: -