Basic Information

Insect: Drosophila grimshawi
Gene Symbol: -
Assembly: GCA_018153295.1
Location: JAECXY010001376.1:24587172-24595357[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 1.5e-05 0.00094 19.2 2.1 1 23 123 145 123 145 0.97

2 18 4.8e-06 0.00031 20.8 0.4 1 23 151 173 151 173 0.97

3 18 0.00071 0.046 13.9 0.9 1 23 179 201 179 201 0.95

4 18 1e-05 0.00066 19.7 3.1 1 23 207 229 207 229 0.97

5 18 2.3e-05 0.0015 18.6 4.7 1 23 235 257 235 257 0.99

6 18 4.2e-05 0.0027 17.8 5.7 1 23 263 285 263 285 0.97

7 18 2.1e-07 1.3e-05 25.1 4.3 1 23 291 313 291 313 0.98

8 18 7.4e-08 4.8e-06 26.5 2.4 1 23 319 341 319 341 0.97

9 18 4.3e-05 0.0028 17.8 6.7 1 23 348 370 348 370 0.97

10 18 7.5e-05 0.0049 17.0 6.5 1 23 376 398 376 398 0.98

11 18 3.4e-05 0.0022 18.1 4.7 1 23 404 426 404 426 0.98

12 18 4.9e-06 0.00032 20.7 8.1 1 23 432 454 432 454 0.98

13 18 4e-06 0.00026 21.0 7.6 1 23 460 482 460 482 0.97

14 18 4.4e-07 2.9e-05 24.0 7.7 1 23 488 510 488 510 0.98

15 18 0.00014 0.009 16.2 9.5 1 23 516 539 516 539 0.95

16 18 4.9e-05 0.0032 17.6 0.9 1 23 545 567 545 567 0.98

17 18 0.00054 0.035 14.3 3.4 1 23 577 599 577 599 0.97

18 18 6.1e-06 0.0004 20.4 1.6 1 23 605 628 605 628 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	1.5e-05	0.00094	19.2	2.1	1	23	123	145	123	145	0.97
2	18	4.8e-06	0.00031	20.8	0.4	1	23	151	173	151	173	0.97
3	18	0.00071	0.046	13.9	0.9	1	23	179	201	179	201	0.95
4	18	1e-05	0.00066	19.7	3.1	1	23	207	229	207	229	0.97
5	18	2.3e-05	0.0015	18.6	4.7	1	23	235	257	235	257	0.99
6	18	4.2e-05	0.0027	17.8	5.7	1	23	263	285	263	285	0.97
7	18	2.1e-07	1.3e-05	25.1	4.3	1	23	291	313	291	313	0.98
8	18	7.4e-08	4.8e-06	26.5	2.4	1	23	319	341	319	341	0.97
9	18	4.3e-05	0.0028	17.8	6.7	1	23	348	370	348	370	0.97
10	18	7.5e-05	0.0049	17.0	6.5	1	23	376	398	376	398	0.98
11	18	3.4e-05	0.0022	18.1	4.7	1	23	404	426	404	426	0.98
12	18	4.9e-06	0.00032	20.7	8.1	1	23	432	454	432	454	0.98
13	18	4e-06	0.00026	21.0	7.6	1	23	460	482	460	482	0.97
14	18	4.4e-07	2.9e-05	24.0	7.7	1	23	488	510	488	510	0.98
15	18	0.00014	0.009	16.2	9.5	1	23	516	539	516	539	0.95
16	18	4.9e-05	0.0032	17.6	0.9	1	23	545	567	545	567	0.98
17	18	0.00054	0.035	14.3	3.4	1	23	577	599	577	599	0.97
18	18	6.1e-06	0.0004	20.4	1.6	1	23	605	628	605	628	0.96

Sequence Information

Coding Sequence: ATGCAGCACGTGAGCGCTGCCAGTTCGGCACCTTCGGTGGTTTCAGCACCGGTGGTGACCACTGGCGGTGGCACCACCATCACCTTGGGCGGACCGCCGTCATTGCCCGGTGTAAAATCGACGGAATCATCTCATAAAGAGGACGGCGGCAAGCAGCCGCCACACGGCATTGAAATGTATAAAGTGAACATTGAGGATATTTCGCAGTTATTCACGTATCACGAGGTCTTTGGCAAAATCCACGGCGATGTGGTTAATCATGTGGCGGCGTTGCTAATGCCGAAAATGGAGGGAGGCATCCATGGCGTTGATGGTCAGTCGAGCGTTGCGTTGGCGCCGGATGGCACGCCCATTGCGACTGGTACGCATGTGTGCGACATTTGTGGCAAGATGTTCCAGTTTCGCTATCAGCTGATTGTGCACCGCCGCTACCACAGCGAGCGCAAGCCGTTCATGTGTCAGGTGTGCGGTCAGGGTTTTACCACATCGCAGGATTTGACCCGTCATGGCAAGATCCACATTGGTGGTCCCATGTTCACGTGCATTGTCTGCTTCAATGTGTTTGCCAATAATACGAGTCTGGAGCGCCATATGAAACGGCATTCAACGGACAAGCCATTCGCCTGCACCATTTGCCAAAAGACTTTCGCACGCAAAGAGCATCTGGACAATCATTTTCGTTCGCATACGGGCGAAACGCCGTTCCGTTGCCAGTACTGCGCCAAGACGTTTACGCGCAAGGAGCACATGGTCAATCATGTGCGCAAACACACGGGTGAGACGCCACATCGTTGCGATATTTGTAAGAAGTCCTTCACGCGCAAGGAACACTATGTTAACCACTACATGTGGCACACTGGTCAAACACCGCATCAGTGCGATGTCTGCGGCAAGAAATACACGCGCAAGGAGCACCTAGCCAACCATATGCGCTCCCACACCAACGAGACGCCGTTCCGTTGCGAAATCTGCGGCAAGAGCTTTAGTCGCAAGGAGCACTTCACCAATCACATACTCTGGCATACAGCAGGTGAGACGCCGCATCGGTGCGACTTCTGCTCCAAGACGTTTACGCGCAAGGAGCATTTGTTAAATCATGTGCGCCAGCACACGGGAGAGTCGCCGCATCGCTGCTCCTACTGCATGAAGACGTTCACGCGCAAGGAGCATCTGGTGAATCATATACGCCAGCACACGGGTGAGACACCGTTCAAGTGCACGTTCTGCACGAAAGCGTTCACACGCAAAGATCACATGGTTAATCATGTACGGCAACATACAGGCGAATCGCCGCACAAGTGCACATATTGCACCAAGACGTTTACGCGCAAGGAGCACCTCACCAATCATGTGCGACAGCATACGGGCGATTCGCCGCATCGCTGCTCCTACTGTAAGAAGACGTTCACCCGCAAGGAGCACCTGACGAATCATGTGCGTCTGCACACGGGCGACTCGCCGCACAAGTGCGAGTACTGTCAGAAGACGTTTACGCGCAAGGAGCATCTCAATAATCATATGCGCCAGCACTCCAGCGACAATCCCCATTGTTGCAACGTCTGCAACAAGCCCTTCACACGCAAGGAGCATCTGATCAATCATATGTCGCGCTGCCACACCGGCGATCGTCCCTTCACCTGCGAGACGTGTGGCAAATCCTTCCCACTCAAGGGCAATCTGCTGTTCCATCAGCGCAGCCACACCAAGGGGCAGGAGTGCGAGCGTCCATTCGCCTGCGAGAAGTGCCCCAAGAATTTCATATGCAAAGGTCACTTGGTCTCGCACATGCGCTCCCATTCGGGAGAGAAACCGCACGCGTGCACACTGTGCAGCAAGGCGTTCGTCGAGCGCGGCAATTTGAAGCGCCACATGAAGATGAATCACCCGGATGCTATGATGCCGCCACCACCCGTGCATCCGCATCCGCAAATACCGGCTGGTGTGCTGACCCAAGTCAAGCAGGAAGTGAAACCGATCATAATTCCCCATCACTCGGCGACGACGACGATGCACACCATCCAGCAGATAACAGCGGGCGCCGCAGCGGCGGGCGGCGGGGCCGTCCAGTTAGCGCCCGGCCTGGTGCCGCTGTCAGACAAGTTGTTGGTTGCTTATCCACCACAAATAAATGAGAAAGCGAAGATGAAGAAGAAGAAAATGAAAATAACCTGCTATATATGGGGCAAGGCGTATTAG
Protein Sequence: MQHVSAASSAPSVVSAPVVTTGGGTTITLGGPPSLPGVKSTESSHKEDGGKQPPHGIEMYKVNIEDISQLFTYHEVFGKIHGDVVNHVAALLMPKMEGGIHGVDGQSSVALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTFCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQECERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDAMMPPPPVHPHPQIPAGVLTQVKQEVKPIIIPHHSATTTMHTIQQITAGAAAAGGGAVQLAPGLVPLSDKLLVAYPPQINEKAKMKKKKMKITCYIWGKAY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00599004;
90% Identity: iTF_00599004;
80% Identity: -