Dgla008591.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila glabriapex
Gene Symbol
RREB1
Assembly
GCA_035042305.1
Location
JAWNLN010000066.1:460965-467940[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 2.3 8.7 0.8 1 21 274 294 274 296 0.93
2 13 0.00035 0.022 15.1 0.2 1 23 306 328 306 328 0.98
3 13 0.00026 0.016 15.5 7.2 1 23 334 356 334 356 0.98
4 13 0.24 15 6.1 1.7 2 20 587 605 587 607 0.93
5 13 0.016 1 9.8 0.2 1 23 756 778 756 778 0.97
6 13 1.3e-05 0.0008 19.6 0.7 1 23 788 810 788 810 0.99
7 13 0.00086 0.054 13.9 2.0 1 23 816 839 816 839 0.97
8 13 0.0031 0.19 12.1 2.0 1 23 1121 1144 1121 1144 0.95
9 13 8.9e-05 0.0056 17.0 0.3 2 23 1541 1562 1540 1562 0.97
10 13 0.15 9.3 6.8 6.3 1 23 1568 1591 1568 1591 0.97
11 13 9.7 6e+02 1.1 3.4 1 23 1709 1732 1709 1732 0.78
12 13 0.0087 0.54 10.7 0.5 3 23 1797 1817 1795 1817 0.96
13 13 0.0014 0.086 13.2 4.8 1 23 1823 1845 1823 1845 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcagcaacagcagcagcagcaacaacaacaacagcaacaatcgcacacagcatcagcaactgcagcagcagcagcagcagcaacacatgAGGATGCTCGGGATTTGGGGTTAATGGAGACGCGACAACGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGacagcaacaccaccagcagcagcagcagcaacagttgccactcTCCGatgaggagcaacagcagcaacagcaacagcagcagcagctgttggacTCATCAGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCgccgttgctgccgctgccagcgcCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAATCGGGCTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTgcttggcagcaacaacaacaacaataataataacaacaacaacaataacaatatcagtaatagcagcagcagcagcgcagtcgcTCAgtcagccgcagcagcagcaacgtcggCAGCGCAGCATGCGCCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGTGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCACGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGTCATTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcagcaacagcagcagcactcgcaacagcagcagtccacacagcagcagcagcagcaggcacagtcgcagcaacaacagcagcgacgccagcaacATGCAggtggagcaggagcagctggtTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcagtccaaccacaacaacaacaatagccacaaaacgaacaacaataataacaacaacaacaataacaacaacaacaatgaggaTGAGCTTGAGCTGGAGGATGAGCAGCTAGTGCTGAGCAGCAAACAGCGACGCCACAAGGCAGccctaaacaacaacaatattattagGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGAGAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTcaccgccgctgctgctgcagagctGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTTTGCCACACATCGGCAGCTGCAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGGaggagcagcaccagcagcaacagcagcagcacgacgAGGAccacgaacagcagcagcacaagcaggaGGTACAGGAGCAGGCTGAGCAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACACGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAACATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGTCGCATGAAACTGCGCGGCGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCCGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTGCGCCACATGCGCACCCACAACGGTGATCGGCCCTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAGCGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAGGCCGATATCCTCACGGAGTTGAGCGGTTATCGTTGTGCAACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGTAAAGgtagctgcaacaacagctgccgcagcagcagcagcagcagcaacaacaacatcgctGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCAGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacagcagcagcaacaacaacagcagcagcagcaacagcagcagcagcaacaaatatttggggCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTCCAGCAATCACCCGGGTTTCCTTTCTTTGGTTTTATggcgccaccgccaccaacaacggcagcggcggcagcggcggcagcggcagcagcagcagcagcagacaagtcaatgacaacaaatccaacagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCAGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcggcGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGGCAcgtgaagcagcagcatccacagtTCTATGCGGAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCCTCGAGTGCTGCCCAAGCGGCAGCCGCTGctcaggcagcagcagccgccgccgccgcagcaatGAGTAATCTCAGCCAGCatcaacagttgcagcagcagcagcaacagttgcagcattcgcattcacatcaCGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttggCGCAGCAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATTttagctacaacaacaacaacaacaacggcaagagcatcagcagcagcaagcagcagcaacaacagttgtgCAACAACACTGGCAACGCTTTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCgaggacgatgaggatgaggaggaggagcaggaatttgatgttgatgaggaggagcaggaggatgAAGAGATGGACATGGACGatgagcatcagcagcagccgcagccgcacgaggaggatgacgatgatgatattgatgatgatgatgcagcagcagcagcagcagcagctgctgcagcagaggcgtcgcagcaacaattgcagccaaCCAAGGACAAGCTGCAATCCAAGCCAATTCAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGCCGAGAAGCAGCCGCATCCTCAATCGGAGTCCATCGGCGGCAATAAGCCGGCGACGCCAACCACAATGAAAACGATGATTGCACAAGCTGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTTGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAACCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTTACCACGAAGAGCAACTGCGATCGTCATCTGTTGCGCAAACATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAATTGGagcgggaacgggaacgggaacacCAACAGTTGATACAACAGTTGCGCCAACAAatggccgctgctgcagcggctgctgtcgctgtggCCGCCGTTGCTGCACCAGCGCATCCACCACCGCCAGACCAATCGCCACCTGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCGccctgctgctggccaagggGGCCATCGAAACGGATGCACAGctgcagcaccaacagcagcagcagcagcagcagcaacagttgccagcgACTGGTGGGGCTCCGCATTCAGATgatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGCAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGCCACATGCGCACCCATTCCGGTGAGCGGCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGAAGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaataacaacaacaatagcaatagcaagcAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacgccctcagcagcaacagcagcagcggcagcaacagctgcagccgcagcagccagTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQQQQQQQQQQSHTASATAAAAAAATHEDARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHQQQQQQQLPLSDEEQQQQQQQQQQLLDSSAQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNNNNNNNNNNNNNNISNSSSSSAVAQSAAAAATSAAQHAPSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQQAQSQQQQQRRQQHAGGAGAAGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNSHKTNNNNNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVESADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQQQQHDEDHEQQQHKQEVQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELSGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTAAAAAAAAATTTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQQQQQQQQQQQQQQQQQIFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGFMAPPPPTTAAAAAAAAAAAAAADKSMTTNPTAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAERQRHRSGHHVMRERAASSSAAQAAAAAQAAAAAAAAAMSNLSQHQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNNNGKSISSSKQQQQQLCNNTGNALVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQEFDVDEEEQEDEEMDMDDEHQQQPQPHEEDDDDDIDDDDAAAAAAAAAAAEASQQQLQPTKDKLQSKPIQAAKKVAETILEQAIKEREEKAAEKQPHPQSESIGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAVAAVAAPAHPPPPDQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQQQQQLPATGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSEDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
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