Dgau012177.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila gaucha
Gene Symbol
hang
Assembly
GCA_035045545.1
Location
JAWNOY010000310.1:1878318-1891717[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.37 26 5.6 1.0 3 23 586 607 585 607 0.93
2 17 1.1 76 4.2 3.2 3 22 714 733 712 733 0.89
3 17 0.0008 0.057 14.0 3.3 1 22 837 858 837 860 0.90
4 17 0.092 6.6 7.5 0.1 2 21 872 891 871 892 0.93
5 17 0.00093 0.066 13.8 0.2 2 23 1016 1038 1015 1038 0.95
6 17 0.0027 0.19 12.4 0.1 1 23 1046 1069 1046 1069 0.96
7 17 0.0002 0.014 15.9 0.2 2 23 1155 1176 1154 1176 0.97
8 17 0.00038 0.027 15.0 2.9 2 23 1275 1297 1274 1297 0.97
9 17 0.03 2.1 9.1 0.2 2 23 1306 1328 1305 1328 0.95
10 17 0.001 0.071 13.7 0.3 1 23 1341 1364 1341 1364 0.97
11 17 0.00017 0.012 16.2 1.1 1 23 1405 1427 1405 1427 0.99
12 17 0.0026 0.18 12.4 0.9 1 23 1435 1458 1435 1458 0.96
13 17 0.09 6.4 7.6 0.4 2 19 1466 1483 1466 1484 0.94
14 17 3.5e-05 0.0025 18.3 0.4 3 23 1596 1616 1595 1616 0.98
15 17 0.0067 0.48 11.1 0.1 1 23 1651 1673 1651 1673 0.97
16 17 0.00079 0.056 14.0 0.6 2 23 1762 1784 1761 1784 0.93
17 17 0.0085 0.61 10.8 0.3 3 23 1840 1860 1840 1860 0.98

Sequence Information

Coding Sequence
ATGAAACTGCCTTTTGGATTTGTGGGCTTCGCTAGCGACGCTTTGTTGCCTGGTGCTCTCGGCTCGGTTATTGATTCTTTCATTTGGCAGGCAGACACAGGGCACACAGCTGAGCCAGCAGGCAGCCAGACGACGAGCAGGCAGGCGCAGGCAGGCATTCAGGCAAACCCAGAGCCAGAGTCGCCCTCGTCATCCACTTTTCGCTCAACACAAAATGGTTGCCTGCTGCTCAGCACAGCTCGCCGCGACGcagcaacgacgacgacgacgacgactctCTGGACTGCGCCCCCGGCAACGACATCATCATCTACGTCGGCGTCGTCGTTGTCGGCACGTTGCTGCTGCGTGTGCTTAGTGCTTGGTGCTGGCACTAGGCGAAAGGCATTTGGTGGTGTTCCCGCCTCGGTGGCACTTGAGAAAGAGATGTGCCCAACAGCAGGATGTCGCTGTGCGGGCGGTTGGatcACGCCATTAGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAACGCCAATGGCTGGACGCCGATAAAAGCAAGCAGCAGACACTTTTAGGTTATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATTgaacatcatcatcagcagcagcagcagcacgaatCGAACATCGATTCGGCGACGGTTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATTCCCTCGCTGAAGAAACGCAAATCGTTAACAGTTTATGTGAGTCCCAAGCAACAgcttcaacagcaacaacaacaacaacagctacaacaacagcagcaactgcatcagcaacaacaacaacagcagcagcaagcagcaagagcaacaagcGCAACGGCGGCGGCGGAGTCACAGCAAACACTGCAGACCCTTTTATTGCAGGTgcccacagcagcagcattggcAACGACGtcaacacagcagcaacagcagcagcagctgcgcaaatatcaacaacaacaacaacgtgtcaagcagcaacagtaccaccagcaacatcaacatagtcatcagcagcagcatcagcgtTTGAGTCGAATTCGTCAGCCCAGACGCCAACAACAGGCGATAATGTCCGGGCAGCGCTTGGTCAAATTCAAgccgaaattgtatttgccGTTGGATATATCAGTACCACCGCTGCCaccgctgctgccgccacaGCAGCCgtcgactgttgctgctggtgctaaGTTGgcgccgttgccgttgccgttgccgttgccactTGATTTTAGCCAGAGTCAGTGTCAGCATCCGAATCAGAATACGAATCAGAGTCAAAAACATGGCAGCGtgttgccgttgccgccgccgctgccagTTGCAGCAATGACCAGCAacgccgctgcctctgcctctgcctctgtctcagccgcagccgcagccgcagtcaCGACTCCTCTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCATTGACGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAGTCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTACGATTATACGGCGCAACACGGCGTGACGGCAGTCGTGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCAAATGTGGCAGCCGCTGGCGACTCGAAGGTGGCCAGCTGCCGGGCCTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGACGCCACGAGCGTAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCCATCACAAAGCCGACGCCGGCACTGGCCGCCGCGCTGGAAATTCAGCGTGCCGCAGCGGCGGCAGCCGCCACCGCGGAGGCAACAAAAGCAGCCGCCGGCGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAACACGTTCATCAAATGCGAAAACGGCGGCTTCGACTACGACAACCCGGAACAGTATCAGCAGCTGCTCACACGCGACAAGGTGGACTTCATACAGGAGAACAACGAGTTTCTGGAGCAATACCAGACGATGACGTGTCGCTGCTGCAACAAGTACTTCAACACCTACAAGAACTTTATGGCCCACGTCCGTAAAAAGTATCCGATGCTGCCACGCAATTTGTGCTTCAACTGCCTAAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAATTTGTATCGGGTCCTCAATGCTCTGCGCCTGAAGCAGCCTAACTTTTCGCATGCCACCGCGTCCGGCGTCGCTGTCTCAACGGATGTGTCTTTGGGGCAGGGCGCTGCTGTGGGTCTTGGTATTGGGATGGTTGGGGCAACAGCACACGACACATCCTCGGAGCGGCCAGAGAAGCTGCGTGCCAAGGAGCTGTTGGTGAACAAACTGTATGAGTGCAAGCTCTGTCCAAAAGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTATGACAAGCACGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCAGCTTCTGTGGACTGGACTTTGCCGATCCGGTGGATCGTCGTCGCCACTACAACAACATGGACTGTATTGTGCGACTGCGCTGCATGACCTGCGATGCCAAGCTGGAGACACATCAGCGCTTTCTCGACCACGTCTATCAGGATCACTTGGGCGGCGTGAGCAGTGATAACGCCTCGACAGCCAACAGCGGCATGGATCATTCGCCCGGCAAGCGCAGTCTGCTGGGCGCCCTGGGCATCGGTGTCAGTCAGTCGTCGAATGACGAGTCGCGCAGCAGCAtccacaacaataacaatgccGTGGAATCGCCATTCACCTCAACACCGAAACTATCGGGCggagctgtggcagctgcggCCAGTGGCGGCTCCGCATCGGGCAGTCGCGATGCACCCAAGTCGCAGTATTTTTCCCGCATGCCCCAGGTGTGCCCGATCTGTGGACAGCAGTACAACAACTATAATAACGTGCTGCGCCACATGGAGTCGAAGCATCCCAATAAACTGCCCGAGACCTACAAGTGTGTACGCTGCGGCCTTGGCTATCCGCGAATCTCATACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGACACTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTCAAATTGGCGGATGGCAGCACGCCCAACGTCTATACCGGGCGCTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgatgatgaggaggaAACCGGAAGCGTTGCTAAGAAGATGCGACTcgacgacagcagcaacaatagcagcatCAACATGAGCGTTGCCAATCAGCAGAAGGAGTGCCTCATCTGCAACGCGGTGTTCAGCAACAACATCGGACTCTCCAATCATATGCGGTCGCATTACACGGCCTCTACGACGACGAGTGCTGCGCTGGCGGCTGCCAATCGCATGACGCCCAAATCGTTGACAATTACAGCGACTCCGCCACTGGACACGACACCGGCAACGTCCTCGagcattgcagcagcagcagcagcagccttgACGCCTGCcccaagtgcagcagcagcaggaacgaCAACTGTTGCCGCCGGTGGCAGCTTGCCGCCAGCGATGGTGCATCAAACGCCGCAGGAGCAGGCGGTTTTCCGGCGTAGCTTGGATCAGGCGGCGGATCGACGCTTTAGGCGCATGCGCTGCCGCATCTGCCAGCGGAGATTCAGCTCGAAGAAGTCCTACCGCTACCACATGCTCACCGACCATCAGGTGCAGAACGTACAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTTGCCTACGAGAAGGGCCTGAAGGTGCATCTGTTCAAGGTGCACGGACGGGCCATCAAGGACGAGATGATTATCAAGCAATTCGAGTGCGATATCTGTTCCACTGTCTACAGCtcggagctggagctgcagcagcacaagcGCAGCGTTCACAAAGCCCAGCTGAGCGCCACAGACGCCGCCAAGTCGTCAGCCAAATCATCTACAGCTACCTCAGCTGCCGACCTGGCCGACACATCGGGCACGGCAGCGGCAGCCCTGCCCCTCTACTGGTACCAGTGCAAGTACTGCCCCTCCAACTTCAACACCAACAAGAAGCTGGCCATTCACATCAACTCGCACGACGAGTTCGACTCGAACGATTATTCGTGCAAGGACTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTTCCCGATCCAGCTGAGTGTACGCTGTGCCGCAAGATGTTCTTTGACCGACAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCCATTACTGCCACCGGCGCCCATCAGCaggatcagcagcagcagcagcagcaacagcagcagcaacagcaacaattgcaaatgcagcagcagcagcgcgccATATTCAAGCACAAAACGggcgatgatgacgatgaggaGGACGAtgatcagctgctgctgctggacgaTGGTGTCGCCGGCAGCGACAGTAACGGTGGCAATGTGATTCatgtggcggcggcggcggtggcggcgtcGTCCTCGTCGTCCTTGAAATCCAATCCAAATACGATTAGCTCGAGCACATTGAAGATACGGATACCGGAGGTGGCGTGCACCATTTGTGGTGCCCGCTTCACCGACCAGGAGATGTTCACCAAGCATATACAGAAGCACGAACAGGATCTGTATGTGGACAATCCATTGGCGGCCATGTTCGACGATGGGCCAGCCGATGCTGGCCAATTTCAGGTGGAGCGCCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacaacaacaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTGCGCGAACTGCATGCAGTGGGTCTGATGcccaaccagcagcagcaccagaagcaacaacagcaacaacaacagcagcaacaacaacaacggaaCAACACATCGAGCAGCTCGAGCAAATCGATGAAGCGAAAACGTGAACTTAAATGCGAATATTGCGCCTCCACATtcataagcaacaacaacctgCGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCCATCATTGAAGTGGATGAGCCGCTGAGTTGTCGCCGTTGCGGCGATCTGCGCTTCGACACCAAAGAGCTGTGGATCGAGCACAAGCTGGCCGATGCCAAGGTGGTGCGTCCCTTCTGTCCATTCCAGTGGGGCTGTGATCTGTGCGGCGAGTATTTGTCGCGCAAAGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCCGTGGCGGTGTCTGCCACAACAACTAAGGCAGCGGCGCCATCAGTTCCCGTACTCTCCCATAAGAATGCTACAGCAAAAAcaggagcaactgcagcagcagcagcagcagctgctggaacagcaacaacagcagcagcagcagcagctggaacaGGAGTCGGAGCAAAGGGCAGCATAAACAGAGCGGCACCAGCTGGAAAGTTGATTAAAAATGAACAAGTGAACGACGAGCAGCTGGCGATGaaggtggaggaggaggaggaggataGTGATATGGATGACGATGATAGCGATAGTCGAGAGGATGGGGATAGTACAAGCGgggacgatgacgacgacgacgatgatgatgatgacgacgacgatgaggGCGATgtcgacgacgatgacgatgaagatgatgaagatgctgtgcaacaacaattgctgcaacaaacaaacaaacagcaacaacaacaacagcaacagcaacagcagcagcccctcaatagcaacaacaacagcaacgatgATGAGGATGATCTCATTGAGGAAGTGATCGAGGATGATGGCATTGTCGAGGAGCTAGACgatgaagacgacgacgacgataacgacgacgatgatgatgatgatgatgatgccacAACAGATGAAAACACAGAGATTGCGGCCAATACGAAACAGCAGGCGAGACGCCTCAACTTCAACTACACGCGCTCCGACAGCGCCAAGCTGAACGGCAATGGCAAACAGACGACGGCAAAGGCGAAGGCGGTGCTGGTCATGCACAGCTCAGAGGATGAGGATGGTGACGGTGTTGACGATGTCGATGATGATGccgaagaggaggaggaggaggaagtgGAAGCAATGACCATCGATGATATTATTGTAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGGTGGTGGTGTTGTTgaggacgatgatgatgatatcGAGGAGGATATGGATGAagatgatgacgacgacgatgacgacgacgacgacgatgatgacgacgatgacgagAATATTAACAACGGCGATGATGCTGTGGTGGTCAGCGGCATCAACATTGGCGGCGCTGAACCTGATgccgatgctgatgctgatggtACATCATCATCTGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGcaaaagcaaaaccaaaaagtCCGGCTTGGATGCAACGAAAGGCGGCagtgctgctcctgctgctgcaacagcaacagcaacaacaacaacaacgacaacaacagcaacagcaacagttgccgctgAAGCCGCAAAAGCAGATGCAGCAAACAGCTTGA
Protein Sequence
MKLPFGFVGFASDALLPGALGSVIDSFIWQADTGHTAEPAGSQTTSRQAQAGIQANPEPESPSSSTFRSTQNGCLLLSTARRDAATTTTTTTLWTAPPATTSSSTSASSLSARCCCVCLVLGAGTRRKAFGGVPASVALEKEMCPTAGCRCAGGWITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDADKSKQQTLLGYLDLNKTENGSSIEHHHQQQQQHESNIDSATVAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQLQQQQQLHQQQQQQQQQAARATSATAAAESQQTLQTLLLQVPTAAALATTSTQQQQQQQLRKYQQQQQRVKQQQYHQQHQHSHQQQHQRLSRIRQPRRQQQAIMSGQRLVKFKPKLYLPLDISVPPLPPLLPPQQPSTVAAGAKLAPLPLPLPLPLDFSQSQCQHPNQNTNQSQKHGSVLPLPPPLPVAAMTSNAAASASASVSAAAAAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVDFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPMLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHATASGVAVSTDVSLGQGAAVGLGIGMVGATAHDTSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSIHNNNNAVESPFTSTPKLSGGAVAAAASGGSASGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEETGSVAKKMRLDDSSNNSSINMSVANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLDTTPATSSSIAAAAAAALTPAPSAAAAGTTTVAAGGSLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSTVYSSELELQQHKRSVHKAQLSATDAAKSSAKSSTATSAADLADTSGTAAAALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQLQMQQQQRAIFKHKTGDDDDEEDDDQLLLLDDGVAGSDSNGGNVIHVAAAAVAASSSSSLKSNPNTISSSTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQQQQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPIIEVDEPLSCRRCGDLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVSATTTKAAAPSVPVLSHKNATAKTGATAAAAAAAAGTATTAAAAAAGTGVGAKGSINRAAPAGKLIKNEQVNDEQLAMKVEEEEEDSDMDDDDSDSREDGDSTSGDDDDDDDDDDDDDDEGDVDDDDDEDDEDAVQQQLLQQTNKQQQQQQQQQQQQPLNSNNNSNDDEDDLIEEVIEDDGIVEELDDEDDDDDNDDDDDDDDDATTDENTEIAANTKQQARRLNFNYTRSDSAKLNGNGKQTTAKAKAVLVMHSSEDEDGDGVDDVDDDAEEEEEEEVEAMTIDDIIVEDDGEDDDDVVGVGGGVVEDDDDDIEEDMDEDDDDDDDDDDDDDDDDDENINNGDDAVVVSGINIGGAEPDADADADGTSSSESESTTTTSHSIAKAKPKSPAWMQRKAAVLLLLLQQQQQQQQQRQQQQQQQLPLKPQKQMQQTA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00476771;
90% Identity
-
80% Identity
-