Basic Information

Insect: Drosophila fuyamai
Gene Symbol: ush
Assembly: GCA_018153365.1
Location: JAECXW010000878.1:5422942-5428208[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.48 11.0 0.0 1 20 270 289 270 291 0.90

2 9 0.0038 0.3 11.6 0.4 3 23 343 363 341 363 0.97

3 9 0.1 7.9 7.2 2.4 2 21 405 424 405 425 0.92

4 9 0.17 13 6.5 2.2 2 21 791 810 790 811 0.93

5 9 0.0085 0.66 10.6 0.0 3 21 863 881 861 882 0.91

6 9 0.0056 0.43 11.1 0.0 2 23 948 969 947 969 0.98

7 9 0.0025 0.2 12.2 1.2 1 23 975 997 975 997 0.99

8 9 0.00069 0.053 14.0 0.9 1 23 1048 1071 1048 1071 0.96

9 9 0.38 30 5.4 0.5 2 20 1186 1204 1185 1206 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.48	11.0	0.0	1	20	270	289	270	291	0.90
2	9	0.0038	0.3	11.6	0.4	3	23	343	363	341	363	0.97
3	9	0.1	7.9	7.2	2.4	2	21	405	424	405	425	0.92
4	9	0.17	13	6.5	2.2	2	21	791	810	790	811	0.93
5	9	0.0085	0.66	10.6	0.0	3	21	863	881	861	882	0.91
6	9	0.0056	0.43	11.1	0.0	2	23	948	969	947	969	0.98
7	9	0.0025	0.2	12.2	1.2	1	23	975	997	975	997	0.99
8	9	0.00069	0.053	14.0	0.9	1	23	1048	1071	1048	1071	0.96
9	9	0.38	30	5.4	0.5	2	20	1186	1204	1185	1206	0.91

Sequence Information

Coding Sequence: ATGTTTGCTGCGGTCGAGATGTCGAATTTCTGGCGAAGCGAGATGCAAACTGCAACGCTTATCCGGCGGCTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACTTCCACTGTCCGCCGCCATAATCTCGGCCAGCATCGCCTTTGGTCGTTATAATATTTCGCCGTGGCCCAAACAGAAACAAATCAGATTGGCCACCATGCGCTTTTCTTTTTGCTCCTCCTCCTGCTCCTTCCCCTTCCTTTTCCACCAGCGTTTTCCACATTCCAAAGATTTGACCGCCCAAGAAATGGGCGAGGAAAAGCAGCAGCAGATGGAGGATCAACTGGATGACCAGTTAGAAGATGCCAGGGACCAACAGGCGACCAACAATAATGATGACGAAGAGGAATATGGTGACTTCGACCAGCCAGAAGAGACTTCTCCCGAGCAGGAACAGGATTTGGGGGAGACAGAGATGGAACGGGAGCACGATCACCAGCCGGAGGAGCAGGATGAAGTGCCAGCCAACAGTCCCAGCACCCCGCCCAGGAGTCCCTGCTCTCCCCAGCTGATTCCCAAGCTGGAACAGCCCGCCACTCCGCCCTCGGAGGCAGAACCTTCTCCGTGTCCCTCGCCCTGCCCCACACCCAAGTTCCCCAAGGTGCGTCTGAATGCGCTCCTGGCCTCAGATCCTGCACTCAAGCCGGATGCCAAGGAGCTAACTCTGCCGGACTCTCGACTGCTGGCTCCCCCGCCGCTCATAAAGCCGGAAACCCCTGCCCCACCGGAGGTGGTGGAACCCCTGCTGAAGCCAGCCAGATTCATGTGCCTGCCCTGCGGGATCGCCTTCAGTTCGCCCTCAACTCTGGAAGCGCATCAGGCCTACTATTGCTCTCATCGGATTAAGGACACCGACGAGACGGGCAGTGATAAGTCGGGAGCAGGAGGATCTGCAGCGGGAGCTGGCGAGGGAGCAGGGTCATCCGGAGGCTCCTCCGAACCACCAGCCAAGATGGCCAGGACAGGAAAGCAATACGGCTGCGCCCAGTGCTCCTACAGTGCGGATAAGAAGGTGTCCTTGAATCGCCACATGCGGATGCACCAGACTTCGCCGGCGGCTCCCACACTGGCCAGCTTGCCAGGTCTCCTCCAGAATGGAATACCACCGCCGGCCGTAACGCCCAGTTCGTTGGAGGATGGCTCTAGTCAACAGCAAACCGATCGCTACTGCAGCCACTGTGATATCCGGTTTAACAACATCAAGACCTATCGGGCCCACAAGCAGCACTATTGCAGCTCCCGGCGACCAGAGGGCCAACTCACTCCGAAGCCAGATGCATCTCCGAGCGCAGGACCGGGACCGGGTTCTAGCGGAGGGTCAGGAGGAGTATCTGTCCAGGCGGCTACTCCCGGCAAGCTCAGTCCGCAGACCAGGAACAAAACTCCTACTCCGGCTATGGTCGCCGTGGCGGCTGCAGCTGCCGCGGCCGCCGCTGCCTCCCTCCAGGCCACGCCCCACCCGCACCCGCCTTTCCTGGCACTGCCCACCCACCCGATCATCATTGTGCCCTGCTCGCTGATCCGGGCGGCCAGCTTTATTCCAGGACCACTGCCCACACCAAACTCGGGTATAGTGAATCCAGAAACCACCTGCTTCACCGTGGACAATGGAACGATCAAGCCCCTGGCCACAGCCCTCATTGGCACCTCTCTGGAGCCCGAACGTCCCTCAGCTCCCTCATCAGCTGCTGAAGCGACGGAGCCCAAGAGCAGTCCACCGGAACCTAAGCGAAAGGAAGCAGGAGGAAGTCGCGAATCTGCGCCTTTGGATCTCTCGCTGCGACGATCGCCGATCTCCGTGAGTTCGTTGAGCCTGCGGCAACGCCACCTGCGCGCTGCTCTTTTAGATGTTGACGAAGCGCTTCTCGGAGTTGGTGGAGCTGGCAAGGAGAATGTGGAGACTCCGCGAGCAGGAGGAAGTGTGACTCCCGAGCAGATCGTGTGCGCCCCCTCCCTGCCGAGCAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATCAGCCCGCGCAGTTCCGGAGCGGGCAGTGCCTCCTCCATGTCACCGCCTGGTCTCAATGTGGCTGTACCCCATCTGCTCGACATGCGATCCATGCTGCCGGCGGACTTTGGACTCACCGAATCGTTGCTGGCCAAAACCAATCCGGAATTGGCTCTCAAACTAGCGGCGGCAGCTGCCGCGGCTGCTGTGGCAGGAGGTGGTGGAGCAGCAGCCTTTCCACCCGCTCCTCTTCCTGCGCAATCGAGTGCCGGAAATCCGGGAAGCGGAGGATCTACCGGTGGATCCCAGCAGCCGCAAATCTATGTAAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTCTGCAAATATGAGAACTACTTGGCTCACAAGCAGCATTATTGCTCGGCAAGGAGTCAAGAGGGTGCGAGTGAAGTGGATGCCAAGTCGGCCGTATCACCATCCAATCCTGGAGCTGGAGGATCGGGAGCTGGCGGGGCAGAAGCTGCTACGTCCGTGGAAACCACTCCGGTGGCATATCAACAACTGATCTGCGCCGCCTGTGGTATTAAGTATACTTCTCTGGACAACCTGCGAGCCCACCAGAACTACTACTGCCCTAAGGGAGGAGCAGCCACTGCCCCCGCCGTGACGCCCGCAGATCCTGGACAACTGGCCATGGCCAAGGAGAAGTGCGGAAAGTGCAAGACCCTGCATGAGATTGGCATACCTTGTCCAGCTCCTGTCACAAATCCTCAGTCAGCACCCGCCTCTAATTCCCAGCAGCCCGCCTCCAATAGTCTGAACAAGTGTCCCGTATGCGGAGTAGTGAGTCCCACGGCCGCGCTGGCCAAGAAGCACATGGAGATGCACGGCACAGTGAAAGCCTACCGCTGCAGCATCTGCCAGTACAAGGGGAATACCCTTCGCGGCATGCGCACCCACATCCGGACCCATTTCGACAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACCTGCATTTTCGAGGAGGAAAGTTCCGCGCCAAGCCAAGAGCTAGCCCCGTCGGCAGGCGGAGCTGCCACAGTTGTCCACGATTCCATGGACCATGCCTCTCAGATGTTTAACTGCGATTACTGCAACTATGCTTCCACTTACAAGGGCAATGTGCTGCGCCACATGAAGCTGATGCATCCGCACGTGGCCATCAACTCACCCTCGATTTCACCCGACACCAGAGATCCGGAAGTGACATCGAACCCCACCCCCAACCAACACTCGAATTCCGATGTTTCCAATGGCGAGGCTACCAGCTTCCTCATCAAGTCTGAGCCTCTTGACCCACAGACGACTCTGAATCTGGTGCACGAGAACAACAACTCGCCGATTGCCACGCCTCACATTAAAGCCGAGCCAATGGACATCGGCGTGGATGCGGTCCCTGGAGGACTGGCCCCGCCGATGGCTTCTCCGCTGGGAAATAGCAGCGTAGCCGCCGCAGCAGCAGCTGTCGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCTACCTGTGACATATCCTTCAACTATGTGAAGACCTACCTGGCGCACAAACAGTTCTACTGCAAGAACAAGCCTATTCGCCCGGAGGTCAACGACAGCCCCAGTCCGAATCACCTCGGCGGCAGCGTGGCGGTGGGCCTGAGCATCGGCGGAATGGTGGCTGGCCATGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MFAAVEMSNFWRSEMQTATLIRRLHLHAMCVPCPRPLPLSAAIISASIAFGRYNISPWPKQKQIRLATMRFSFCSSSCSFPFLFHQRFPHSKDLTAQEMGEEKQQQMEDQLDDQLEDARDQQATNNNDDEEEYGDFDQPEETSPEQEQDLGETEMEREHDHQPEEQDEVPANSPSTPPRSPCSPQLIPKLEQPATPPSEAEPSPCPSPCPTPKFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLIKPETPAPPEVVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKDTDETGSDKSGAGGSAAGAGEGAGSSGGSSEPPAKMARTGKQYGCAQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPGLLQNGIPPPAVTPSSLEDGSSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPSAGPGPGSSGGSGGVSVQAATPGKLSPQTRNKTPTPAMVAVAAAAAAAAAASLQATPHPHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALIGTSLEPERPSAPSSAAEATEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISVSSLSLRQRHLRAALLDVDEALLGVGGAGKENVETPRAGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHLLDMRSMLPADFGLTESLLAKTNPELALKLAAAAAAAAVAGGGGAAAFPPAPLPAQSSAGNPGSGGSTGGSQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDAKSAVSPSNPGAGGSGAGGAEAATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAATAPAVTPADPGQLAMAKEKCGKCKTLHEIGIPCPAPVTNPQSAPASNSQQPASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEESSAPSQELAPSAGGAATVVHDSMDHASQMFNCDYCNYASTYKGNVLRHMKLMHPHVAINSPSISPDTRDPEVTSNPTPNQHSNSDVSNGEATSFLIKSEPLDPQTTLNLVHENNNSPIATPHIKAEPMDIGVDAVPGGLAPPMASPLGNSSVAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEVNDSPSPNHLGGSVAVGLSIGGMVAGHGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00494666; iTF_00588426; iTF_00529835;
80% Identity: -