Basic Information

Insect: Drosophila carrolli
Gene Symbol: ush
Assembly: GCA_018152295.1
Location: JAECXJ010000159.1:24083775-24089776[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.006 0.46 11.0 0.0 1 20 231 250 231 252 0.90

2 9 0.0037 0.28 11.7 0.4 3 23 304 324 302 324 0.97

3 9 0.1 7.5 7.2 2.4 2 21 366 385 366 386 0.92

4 9 0.17 13 6.5 2.2 2 21 752 771 751 772 0.93

5 9 0.0083 0.63 10.6 0.0 3 21 824 842 822 843 0.91

6 9 0.0054 0.41 11.2 0.0 2 23 909 930 908 930 0.98

7 9 0.0025 0.19 12.3 1.2 1 23 936 958 936 958 0.99

8 9 0.00067 0.051 14.0 0.9 1 23 1009 1032 1009 1032 0.96

9 9 0.38 28 5.4 0.5 2 20 1147 1165 1146 1167 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.006	0.46	11.0	0.0	1	20	231	250	231	252	0.90
2	9	0.0037	0.28	11.7	0.4	3	23	304	324	302	324	0.97
3	9	0.1	7.5	7.2	2.4	2	21	366	385	366	386	0.92
4	9	0.17	13	6.5	2.2	2	21	752	771	751	772	0.93
5	9	0.0083	0.63	10.6	0.0	3	21	824	842	822	843	0.91
6	9	0.0054	0.41	11.2	0.0	2	23	909	930	908	930	0.98
7	9	0.0025	0.19	12.3	1.2	1	23	936	958	936	958	0.99
8	9	0.00067	0.051	14.0	0.9	1	23	1009	1032	1009	1032	0.96
9	9	0.38	28	5.4	0.5	2	20	1147	1165	1146	1167	0.91

Sequence Information

Coding Sequence: ATGTTTGCTGCGGTCGAGATGTTGAATTTCTGGCGAAGCGAGATGCAAACTGCAACGCTTATCCGGCGGCTCCATCTGCATGCCATGTGTGTGCCATGTCCACGTCCACTTCCACTGTCCGCCGCCATAATCTCGGCCAGCATCGCCTTTGATTCCAAAGATTTGACCGCCCAAGAGATGGGCGAAGAAAAGCAGCAGCAGATGGAGGATCAACTGGATGACCAGTTAGAAGATGCCAGGGACCAACAGGCGACCAACAATAATGATGACGAAGAGGAATATGGTGACTTCGACCAGCCAGAAGAGACTTCTCCCGAGCAGGACCAGGATTTGGGGGAGACAGAGATGGAACGGGACCACGATCACCAGTCGGAGGAGCAGGATGAACTGCCAGCCAACAGTCCCAGCACCCCGCCCAGGAGTCCCTGCTCTCCCCAGCTGATTCCCAAGCTGGAACAGCCCGCCACTCCGCCCTCGGAGGCGGAACCTTCTCCGTGTCCCTCGCCCTGCCCCACGCCCAAGTTCCCCAAGGTGCGTCTGAATGCGCTCCTGGCCTCAGATCCCGCACTAAAGCCAGATGCCAAGGAGCTAACTCTGCCGGACTCTCGTCTGCTGGCTCCCCCGCCGCTCATAAAGCCAGAAACCCCAGCCCCATCGGAGGTCGTAGAACCCCTGATGAAGCCAGCCAGATTCATGTGCCTGCCGTGCGGGATCGCCTTCAGTTCGCCCTCGACTCTGGAAGCGCATCAGGCCTACTATTGCTCTCATCGGATTAAGGACACGGACGAGACGGGCAGTGATAAGTCGGGAGCAGGAGGATCTGCAGCGGCAGCTGGCGAGGGAGCAGGGTCATCCGGAGGCTCCTCCGAACCACCAGCCAAGATGGCCAGGACAGGAAAGCAATACGGCTGCGCCCAGTGCTCCTACAGTGCGGATAAGAAGGTGTCTTTGAATCGCCACATGCGGATGCACCAGACTTCTCCGGCGGCTCCCACACTGGCCAGCTTGCCAGGTCTCCTCCAGAATGGAATACCACCGCCGGCCGTAACGCCCAGTTCGTTGGAGGATGGCTCTAGTCAACAGCAAACCGATCGCTACTGCAGCCACTGTGATATCCGGTTTAACAACATCAAGACCTATCGGGCCCACAAGCAGCACTACTGCAGTTCCCGGCGACCAGAGGGCCAACTCACCCCGAAGCCAGATGCATCTCCGAGCGCAGGATCGGGGCCGGGTTCCAGCGGAGGGTCAGGAGGAGTATCTGTCCAGGCGGCTGCTCCCGGCAAGCTCAGTCCGCAGACCAGAAACAAGACTCCCACTCCGGCAATGGTCGCCGTGGCGGCTGCAGCTGCCGCGGCCGCCGCTGCCTCCCTCCAGGCCACGCCCCACCCGCACCCGCCTTTCCTGGCACTGCCCACCCACCCGATCATCATTGTGCCCTGCTCGCTGATCCGGGCGGCCAGCTTTATTCCAGGACCACTGCCCACACCAAACTCGGGTATAGTGAATCCAGAAACCACCTGCTTCACCGTGGACAATGGAACGATCAAGCCCCTGGCCACAGCCCTCATCGGCACCTCTCTGGAGCCCGAACGTCCCTCAGCTCCCTCGTCAGCTACTGAGGCGACTGAACCCAAGAGCAGTCCACCGGAACCCAAGAGAAAGGAAGCAGGAGGAAGTCGCGAATCTGCGCCTTTGGATCTCTCGCTGCGACGATCGCCGATCTCCGTGAGTTCGTTGAGCTTGCGGCAGCGCCACCTGCGCGCTGCTCTTTTAGATGTTGACGAAGCGCTTCTCGGAGTTGGTGGAGTTGGCAAGGAGAATGTGGAGACTCCGCGACAAGGAGGAAGTGTGACTCCCGAGCAGATCGTGTGCGCCCCCTCCCTGCCGAGCAGTCCTTCGATGAGTCCCTCGCCCAAGCGACGAGCCATCAGCCCGCGCAGTTCCGGAGCTGGCAGTGCCTCCTCCATGTCACCGCCTGGTCTCAATGTGGCTGTGCCCCATATGCTCGATATGCGATCCATGCTGCCGGCGGACTTTGGTCTCACCGAATCGTTGTTGGCCAAAACCAATCCGGAATTGGCGCTCAAACTAGCGGCAGCGGCTGCCGCGGCTGCTGTGGCAGGAGGTGGTGGAGCAGCAGCCTTTTCACCCGCTCCTCTTCCTGCGCAATCGGGTGGCGGAAATCCGGGAAGCGGGGGATCTACAGGTGGCTCCCAGCAGCCGCAAATCTATGTAAAGAAGGGCGTGTCCAAGTGCATGGAGTGCAATATTGTGTTTTGCAAATATGAGAACTACCTGGCTCACAAGCAGCATTATTGCTCGGCAAGGAGTCAAGAGGGTGCGAGTGAAGTGGATAACAAGTCGGCCGTTTCACCGTCCAATCCTGGAGCTGGAGGATCAGGAGCTGGCGGGGCAGAAGCTGCTACGTCCGTGGAAACCACTCCGGTGGCATATCAACAACTGATCTGCGCCGCCTGTGGTATTAAGTATACTTCTCTGGACAACCTGCGTGCTCACCAGAACTACTACTGCCCCAAGGGAGGAGCAGCTACTGCCCCCACCGTGACGCCCGCAGATCCTGGACAACTGGCCATGGCCAAGGAGAAGTGCGGAAAGTGCAAGACCCTGCATGAGATTGGCCTGCCTTGTCCAGCTCCTGTCACAAATGCACAGTCAGCACCCGCCTCTAATTCCCAGCAGCCCGCCTCCAATAGTCTGAACAAGTGTCCCGTATGCGGAGTAGTGAGTCCCACGGCGGCGCTGGCCAAGAAGCACATGGAGATGCATGGCACAGTGAAAGCCTACCGCTGCAGCATCTGTCAGTACAAGGGGAATACCCTTCGCGGCATGCGCACCCACATCCGGACCCATTTCGACAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACCTGCATTTTCGAGGAGGAAAGTTCCACGCCAAGCCAGGAGCTGCCCCCGTCGGCAGGCGGAGCTGCAACAGTTGTCCACGATTCCATGGACCATGCCTCTCAGATGTTTAACTGCGATTACTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTGCGCCACATGAAGTTGATGCATCCGCATGTGGCCATCAACTCACCCTCGATTTCACCCGACACCAGAGATCCGGAAGTGACATCGAACCCCACTTCCAACCAACACTCGAATTCCGATGTCTCCAATGGCGAGGCTGCCAGCTTCCTCATCAAGTCGGAGCCCCTTGACCCACAGCCGACGCTGAATTTGGTGCACGAGAACAACAACTCGCCGATTGCCACGCCCCACATTAAAGCCGAGCCCATGGACAACGTCGTGGATGCGGCCCCTGGAGGACTGGCCCCACCGATGGCTTCTCCGCTGGGAAACAGCAGCGTAGCCGCAGCAGCCGCAGCTGTCGCCGCCGCCGAGGTGATGAAGAAGTACTGCTCTACCTGTGACATATCCTTCAACTACGTGAAGACCTACCTGGCGCACAAACAGTTCTACTGCAAGAACAAGCCTATTCGCCCGGAGGTCAACGACAGCCCCAGTCCGAATCACCTGGGCGGCAGCGTGGCGGTGGGCCTGAGCATCGGCGGAATGGTGGCTGGCCATGGCCAGCAGAAGAACAAGGAGAACCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MFAAVEMLNFWRSEMQTATLIRRLHLHAMCVPCPRPLPLSAAIISASIAFDSKDLTAQEMGEEKQQQMEDQLDDQLEDARDQQATNNNDDEEEYGDFDQPEETSPEQDQDLGETEMERDHDHQSEEQDELPANSPSTPPRSPCSPQLIPKLEQPATPPSEAEPSPCPSPCPTPKFPKVRLNALLASDPALKPDAKELTLPDSRLLAPPPLIKPETPAPSEVVEPLMKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRIKDTDETGSDKSGAGGSAAAAGEGAGSSGGSSEPPAKMARTGKQYGCAQCSYSADKKVSLNRHMRMHQTSPAAPTLASLPGLLQNGIPPPAVTPSSLEDGSSQQQTDRYCSHCDIRFNNIKTYRAHKQHYCSSRRPEGQLTPKPDASPSAGSGPGSSGGSGGVSVQAAAPGKLSPQTRNKTPTPAMVAVAAAAAAAAAASLQATPHPHPPFLALPTHPIIIVPCSLIRAASFIPGPLPTPNSGIVNPETTCFTVDNGTIKPLATALIGTSLEPERPSAPSSATEATEPKSSPPEPKRKEAGGSRESAPLDLSLRRSPISVSSLSLRQRHLRAALLDVDEALLGVGGVGKENVETPRQGGSVTPEQIVCAPSLPSSPSMSPSPKRRAISPRSSGAGSASSMSPPGLNVAVPHMLDMRSMLPADFGLTESLLAKTNPELALKLAAAAAAAAVAGGGGAAAFSPAPLPAQSGGGNPGSGGSTGGSQQPQIYVKKGVSKCMECNIVFCKYENYLAHKQHYCSARSQEGASEVDNKSAVSPSNPGAGGSGAGGAEAATSVETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGGAATAPTVTPADPGQLAMAKEKCGKCKTLHEIGLPCPAPVTNAQSAPASNSQQPASNSLNKCPVCGVVSPTAALAKKHMEMHGTVKAYRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEESSTPSQELPPSAGGAATVVHDSMDHASQMFNCDYCNYASTYKGNVLRHMKLMHPHVAINSPSISPDTRDPEVTSNPTSNQHSNSDVSNGEAASFLIKSEPLDPQPTLNLVHENNNSPIATPHIKAEPMDNVVDAAPGGLAPPMASPLGNSSVAAAAAAVAAAEVMKKYCSTCDISFNYVKTYLAHKQFYCKNKPIRPEVNDSPSPNHLGGSVAVGLSIGGMVAGHGQQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00505683;
90% Identity: iTF_00512282;
80% Identity: -