Basic Information

Insect: Drosophila fuyamai
Gene Symbol: -
Assembly: GCA_018153365.1
Location: JAECXW010000062.1:12051319-12056482[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 7.4e-15 3.3e-11 42.6 0.1 7 72 597 658 591 661 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	7.4e-15	3.3e-11	42.6	0.1	7	72	597	658	591	661	0.88

Sequence Information

Coding Sequence: ATGAGCTCGCCCGACGATATTCCTGGACCGTCAAAGCCGCGCGCCAAGAAGCGCTCACCACGCAGCTCCAGCAGCGATTCCAAGTCGCAGGCATCGCCGCCGCTGACGACCAGCAATGGACATGGATCCGGATCGGGAGGCGAACGTAGTCCCGCCGGCAATCAAAGTCCCGCTGCTGGTCGAAGTCCCGCAGGTGGACTTAGTCCAGGCTTAGGACCAACCAACATGCGGGACCGCCTGCTGGTGGCCAATGCCATGGCCATAGAGCTATCGACTAGCGAGCAGGAAGACTCCACTAGCTCTTCGTCGCCGCAGATGAATGGTCATCATCATAACGAATCTGGCGAGTCCGATCAGCAAAATGGAGCGGCCGTAAATGGAGATTCCCGTAAGTCCAAGAAGAAAAAGAAGAAGAGCAGGAGTCGTCGTGAACGCCGCATATCTGGAGATACCGCGCTCATGGGCTGGACGGGCGGATTCCCGAAGCTAACAGCCATGGCCAGCATTGACAGTAGCTCTGATATGGAGCCCCAGTCGCCGGGCGAGCTGCGGGCACTGGGCAGGAGAGGATTGAGGGTGTTTCCAAGAGTTGAACCGCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTCCTCTCTGTCCTCAAACTCTGACTTGATTATGACGATATCAACGCCACCAGGACGTGAACCAGAACCAGAACAGCAACAAAACCCAGAACCAGAACAGCCAATCACTTTAGCAACTGTAACTAGTACAAATCAAACCACAACAACTACGACAACTAGCAACAGCAACAGCAACAACAATTCCAACGCAACTGGTACTGCAACAACTTCAAGTCCAAGCACAACGGCATCCAGCATGCAACAAACAGAATTAGACAACCAGGAGAAGAATATGGAGATGGAGCAGCCGGCGAAGGCAGAGGATAACCAGCAGCCAGCGAAGGAAGAGGATAAGCAGCAGCCGGCGAAGGAAGAGAATAAGCAGCAGTCGGCGAAAGCAGAGCATAATCAGCAGCCGGCGAAGGCAGGGGATAATCAACAGCCAGCGAAGGCAGAAGATAACCAGCAGCCGGCGAAGAATGAGGATAACCAGCAGCCGGCGAAGGCAGACGATAACCAGTCGCCGGCAAAGGCAGATGATAAGCAGCAGCCAGCGGAGAATGAGAATGAGGAGGAGAAGGAGGAGGAAATTGAACCCCTGGTGGTGGCCGAGGATGAGGTCAGCTCGGATATCCAACTGGTGTCTACTACGTCGTCTTCGCCACCGCCACCACCGGATCCGGCTCCCAATCCTCGTTCCCGCAAACGCGCATTCAGTCCGACTAAAAAAGACGCCAAGCTGGCCAAACAGGAGGATACCGAGAAAAAGAAGAAAAAGATGGAGGAGGAACCTGAAGTTCCGTTGGTCAAAAGTCCCAATAAATTGGAGGAAACAGACCAACCCGTGTCCAGTCGCTTTGCCAAGCGTGCCAAGTCTCTGAGTACCCAGACATCGCAGCCGGAGCAGGTGCGCCGTACCTCGCGCTTTAGCAGCCAGGAGTTGTTGACTGAGGAGCAGATCAAACTGGATACACCGGCACCCACCATCAACAAGGAGCCTGATGCCCAAATCGAGGCCATACCGGAACCACCGCCCACAGCCTCAGCCTTAAAGCTGAAAGCCACCGACCAGTTCTATCGCCTGCCCTTCGCCTACGGCTGGAAGCGTGAGTTCGTCCTGCCCAGCACTGGGAATCAAAAGCGTCGCACTGGTGACGTTTTCTTCATAGCACCCAATGGACGCAAGCTACGATCGCGCGAAGATATTGTGCCCCTGCTGGAGGGCGAGCTGACCATCGAGCACTTCTGCTTCCAGCGTCAGGCGCAAGAGGCGGGACCAGAGTACGAACTGGTGCGTCGGGCCACGCCCGCCAGCGCATCGCGTCGGAAATCCCAGCATGCTCAGCTTCAGCCCGCTCCATTGCCAGTCACCGGAAAGCGCGTGTCGAAGCCCAAAGTGCCCAAGGGGGCAAGTCCACCGAGTGAGGGCTGGACCGCCACTATGGCGGTAAAGGGGAATTCTCGAGTGCTGGCCAGCAGCAACGGCAGCAGCTCAGCCGGAACTTCAGGAGCGAGCATATCATCTCGCAAGCGAAACTTCATGTCTAGACAGTCGTCGAGGACTTCAAACGTGATGCTCGCGGGCTGTGTGCGTTGCCAAGCTCCATTGCAGCCAACTGGGTCCAAGCAGGTATCGCCCAGGACCAACACTTGCCAGAACTGCTTGAAGATAAAGCGAGAAAAAGAGAGGGAATCTGAGAAGAACGATATGGTAGCCGAGCCGCAGCTAGAGGATGAAGATCATGATGATGATCAGGATGATGATGACAACGCAAGCGTCGGCAGTCTGTTGGAGATCGGCGAGGAGATTGAGGTGCCCGGTCATCATCCGCCGGCGCAGCTTTTCAATAACCTGGGACAACGACGTTCGCCCAAGGAGCAGGAGGTTGTTGTGATTGGGGGGCGCAAGGCCATAGCCATCAAAGCCGATCCGCCGCGTCCCCAAGTGAAAGTGGTTCCACGCCATCCGGATTTAACCAGCTACGAAAAGATCTTCAACAAGCGCATGCAGGCCAAAAAGTCGCGCCACGACCTCGTGGAGAGCCTGGGTGATGCTCACAACGGCTGTCAGGTGCTGATGGCTATTATGAAAACTATGAACCTGAAGGAACGTGCCAACATGTCGCGGGTGTGCAAGACCTGGGCTATGGTTAGCCGTGAGAACGCCGTGTGGCGTTCGGTCCGCCTGCGCGACACTCATATCGGAAATTGGGTGTTCTGTTTACGTGAACTGGCCCGCCACCGCACTCGTGAGTTGGACATGATGGGCGTGATTATGGCTAAACCGCAGATTCGCATGACCGGTGATCTGCGCGTACTCAAAGCATTGCGCATACTACGTACCGATACAACTGATGCGGAGTTCCTCCAGTTGGTCTTTCGCCATCTGCCTCAGTTGCTCGAGTTAAGAGCCACTTGCTTGAGCGGAACATTGAGCCTGGCGCACTTGGAGCGGACTGATGAGCTGCGCGTACTTCGAATCCAGATGACGGAGGCAAAGGCTACAGTTGGATCACTAAATTCGCTGGCAAAACTAAAGCATCTAACTGAGTTAAGTCTGCGTGGAGTGAACAATCTGGCCAGGCTGAACTTGCTGCTCTTGAAGGATCTAACTAATCTGGAGGTGCTATCGTTGGGCTCCTGCCAAGACATAAACGGTGAGAGGCTCGGCAAGCAAGTGCTGCCCAATCTGAAGGCTCTACGCTCCTTTCGCCTGGAGAACGATCACAAAGGAATGGCTATGTTTCCGGTAGATGAGATTATGCGAGGTCTGGCTCGCGCAGGTGGAGTGCGTCGCCTGGAGCTGGTGAACGTCGACGTGGACGGCGGTTTTAGCGTTTTGCTCGCCAGCTGTCCCAGTATAACGGAGCTGCTGCTGACCCCCAAATGTATGCATAATACGGCCAACATGACTAATGCCGTAATGCAGGCTATCAGCGACAATGCCGAGCAGTTGCTTGTGTTCCGCTTGGGATTGGTAACGCAGCTGTTAAGTGCCACTGGTACGCTGTACAAGGGGACGGGCAAGGACGTGATACCAGTGCAGCGCCCAGTGCCGGGAGTTCCGGCCAGCGATCACCTAAATCGCTGCTCCGCTGAGGATAATTGCCAGGAGTCGGATCACGATCAATGCGTGGCCTTTCTGCCCGTGGAACGTCTGGAAGCGATCTTGCATCACATGATGCCGCAGGCTTGGCTTTCGGTGGCCAAGGTGGCCATGTGCGACACCACCAAGATCAAGTTCCTGCCCCGACCAGAGGAGAGCAGCGAGGAGAACTTTTAG
Protein Sequence: MSSPDDIPGPSKPRAKKRSPRSSSSDSKSQASPPLTTSNGHGSGSGGERSPAGNQSPAAGRSPAGGLSPGLGPTNMRDRLLVANAMAIELSTSEQEDSTSSSSPQMNGHHHNESGESDQQNGAAVNGDSRKSKKKKKKSRSRRERRISGDTALMGWTGGFPKLTAMASIDSSSDMEPQSPGELRALGRRGLRVFPRVEPXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSSLSSNSDLIMTISTPPGREPEPEQQQNPEPEQPITLATVTSTNQTTTTTTTSNSNSNNNSNATGTATTSSPSTTASSMQQTELDNQEKNMEMEQPAKAEDNQQPAKEEDKQQPAKEENKQQSAKAEHNQQPAKAGDNQQPAKAEDNQQPAKNEDNQQPAKADDNQSPAKADDKQQPAENENEEEKEEEIEPLVVAEDEVSSDIQLVSTTSSSPPPPPDPAPNPRSRKRAFSPTKKDAKLAKQEDTEKKKKKMEEEPEVPLVKSPNKLEETDQPVSSRFAKRAKSLSTQTSQPEQVRRTSRFSSQELLTEEQIKLDTPAPTINKEPDAQIEAIPEPPPTASALKLKATDQFYRLPFAYGWKREFVLPSTGNQKRRTGDVFFIAPNGRKLRSREDIVPLLEGELTIEHFCFQRQAQEAGPEYELVRRATPASASRRKSQHAQLQPAPLPVTGKRVSKPKVPKGASPPSEGWTATMAVKGNSRVLASSNGSSSAGTSGASISSRKRNFMSRQSSRTSNVMLAGCVRCQAPLQPTGSKQVSPRTNTCQNCLKIKREKERESEKNDMVAEPQLEDEDHDDDQDDDDNASVGSLLEIGEEIEVPGHHPPAQLFNNLGQRRSPKEQEVVVIGGRKAIAIKADPPRPQVKVVPRHPDLTSYEKIFNKRMQAKKSRHDLVESLGDAHNGCQVLMAIMKTMNLKERANMSRVCKTWAMVSRENAVWRSVRLRDTHIGNWVFCLRELARHRTRELDMMGVIMAKPQIRMTGDLRVLKALRILRTDTTDAEFLQLVFRHLPQLLELRATCLSGTLSLAHLERTDELRVLRIQMTEAKATVGSLNSLAKLKHLTELSLRGVNNLARLNLLLLKDLTNLEVLSLGSCQDINGERLGKQVLPNLKALRSFRLENDHKGMAMFPVDEIMRGLARAGGVRRLELVNVDVDGGFSVLLASCPSITELLLTPKCMHNTANMTNAVMQAISDNAEQLLVFRLGLVTQLLSATGTLYKGTGKDVIPVQRPVPGVPASDHLNRCSAEDNCQESDHDQCVAFLPVERLEAILHHMMPQAWLSVAKVAMCDTTKIKFLPRPEESSEENF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00588139; iTF_00494381; iTF_00529559;
90% Identity: iTF_00529559;
80% Identity: -