Dfun012863.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila fungiperda
Gene Symbol
RREB1
Assembly
GCA_035042345.1
Location
JAWNLM010000235.1:2405-8845[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.033 2.3 8.8 0.8 1 21 256 276 256 278 0.93
2 13 0.00031 0.021 15.2 0.2 1 23 288 310 288 310 0.98
3 13 0.00023 0.016 15.6 7.2 1 23 316 338 316 338 0.98
4 13 0.22 15 6.2 1.7 2 20 569 587 569 589 0.93
5 13 0.014 1 9.9 0.2 1 23 736 758 736 758 0.97
6 13 1.1e-05 0.00078 19.7 0.7 1 23 768 790 768 790 0.99
7 13 0.00076 0.053 13.9 2.0 1 23 796 819 796 819 0.97
8 13 0.0027 0.19 12.2 2.0 1 23 1085 1108 1085 1108 0.95
9 13 7.9e-05 0.0055 17.0 0.3 2 23 1451 1472 1450 1472 0.97
10 13 0.13 9.2 6.9 6.3 1 23 1478 1501 1478 1501 0.97
11 13 8.6 5.9e+02 1.2 3.4 1 23 1620 1643 1620 1643 0.78
12 13 0.0078 0.53 10.8 0.5 3 23 1700 1720 1698 1720 0.96
13 13 0.0012 0.085 13.3 4.8 1 23 1726 1748 1726 1748 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcaacagcagcaacaacaacaacaatcgcacacagcagcagcagcagcagcagcaacacttgaGGAAGCTCGCGATTTAGGCTTAATGGAGACGCGACAACGTCGCGATTCGAGTACATCTGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCAAAAaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGGAAACTGcgacagcaacaccagcagcagcaacagttgccgctCTCCGATGAGGACCAGCatcagaagcaacagcagcagctgttgggCTCTTCAGCGCAACGACCGCGTCACAAGCAGCAACGCAGCGCTGTTCCTGCCGCCACCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGAGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCTGCCAACGGTGATTTATCCGAGTCTGGCTTCGTCGATGGCAGCGCCCTCAGTGGCTATCTgcttggcaacaacaacaacaataacaacaacaacaacaatgttagtagtagtagcagcagcagcgcagtcgCTCagtcagcagcatcagcagcagcgtcggcAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAAGGCCTTTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGcacatgaaatatttgtgcCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTAGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcaacagcagcacagctcgcagcagcagcaatcaagccaacagcagcagcagcaggcacagtcgcagtcgcaacagcagcaacagcgacgccAGCAACATGCGggtggagctggagcagctggcCCCGAATCGGGATCGGCACAGTTGTTGACAACGCGAGCCGAGAGCTATGAGAGTGATGCTAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccccaacaacaatagccacaaaacgaacaacaataacaacaataagaacaacaacaacaacaacaatgaggaTGAGATGGAGCTGGAGGATGAGCAGCTAGTGTTGAGCAGCAAACAGCGACGCCTAAAGGCAGtcctaaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGGCGGATGATGATTCGGATGTGGACAGCGTTGATAGTGTTGCCCAGGTGATAACAAGCACACCAGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCGAGCCACTCGCATTCGGAATCGCATTCaccgccactgctgctgcagagtTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAATGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGTGGATTGCCACCGCTCCTTGGTGTCAGCTCATCGCCACTGCACAAGCAGGAGGAGAACGaactggaggaggaggagcagcaacagcagcagcacgaggAGGACCATGaacagcaacacaagcagGAGGAACAGGAGCAGGCTGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAGCGCTCCTGCCATCTCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGACATTCAAAGCATTCTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGTGATGGCGAGGAGGAGGCTCAGGATGCCTTCACCAATGAGTTCCGCAGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTATGCACTGCCGTCTTTCCCAATCTTCGGGCACTCAAGGGCCACAACCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGCCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTGCGTCACATGCGCACTCACAACGGGGATCGGCCCTACGAGTGCGCCGTCTGCAACTATGCGTTCACCACCAAGGCGAACTGTGAGCGCCATTTGCGCAATCGACATGGAAAGACCAGTCGGGATGATGTGAAACGTGCGATTGTCTACCATCCAGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGCACCGATGCCGATATCCTAACCGAGCTGAGCGGCTATCGCTGTCCAACACCCACAGAGCACAGTTCCTCGGCTAGCTCCTCGTCCCAACTGAAGCACATGTTGCTGGCGGAGCCGACACCGGCCGTAAaggtaacagcaacagcagcagcaacaacatcgatGCCGCAACGACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTGAGCATGGATGCGCTAGACTTGAGCAAGAAGCCCGCACAGCTGCTGGCTGAGCAAAGGGAGCAAAGGGACCAGCTCGAAAGACACgaattgctgttgcagcagcaacagcagcagcagcagcaacagcaacaacaacagcagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTCTTGCGCAGCTTCATGCTCCAGCAGTCACCCGGTTTTCCTTTCTTTGGTTTTATGGCGCCACCGCCACCAACAGCGGCatcagtagcaacagcagcagacaagtcaatgccaacaaatccaacagcagcagcagccggcgcaacagcagcaacaattgctgcattGCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACGCTGCGTTCCAACATGGAGCGGCACgtgaagcagcagcatccacagTTCTATGCGCATCGCCAACGACACCGCAGCGGTCATCATGTGATGCGTGACCGGGCTGCATCATCCAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagcggccgcAGCAATGAATAATCTCAGagccagcaacaCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCACCAATCCGCTGCTGCATtttaactacaacaacaacagcatcggcaacaagcagcagcagcagcaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGATGATGAGCCGCCCAAGCTGATTATTGACGAGGATGATGAGGATGTGGAGGGCGAGGGCGAGTGcgaggacgatgatgatgaggaggaggagcatgAATTTAATGTCGATGACGAGGAGCAGGAGGATGAAGAGATGGACTTGGACGATGagtatcagcagcagcagctgccgcacgaggatgatgatgataatgatgatgataatgatgcagcaGCAGCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGCAGCGGAGATCATAATCAAGGAGAACGAGGAGAAGGCCTCCGAGAAGCAGGCGCGTTGCCAATCTCAGTCGAGAGGCGGCAATAAGCCGGCGacgccaacaacaatgaaaacaatgatTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAAGATCTGGTGCCTGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCATTCAATAGCTATTTCCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCATTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCTGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACAGGCCGAACGGGAGCAGCTCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAATTGGAACGGGAAAGGGAGcgggaacagcaacaattgatACAACAGTTGCGCCAACAAatggccgctgctgcagcagctgttgctgttgccgttgtcacTGCACTAGCGCATCCACCAGCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGACCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTCCACTCGCACGAATTCGCACTGCTCCTGGCCAAGGGGGCCATAGAGACGGATGCACAACTGCAGCATCAACAGTTGCCAGTGGCTGGTGGCGCCTCGCATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGCAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGCGAGCGTCCTTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGTTCCGATGATGAGCAGATGTTGCACTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacacttgccagaacaacaacaacaatagcaacaacaataacaacaacaatagcaatagcaagcAGGTGCTGCGCGAGCTGCTGGGCAAGGCAAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCAGAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcagcagcagcagcagcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATTCTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGAGAGAGTGA
Protein Sequence
MLATQQQQQQQQQQQSHTAAAAAAATLEEARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHQQQQQLPLSDEDQHQKQQQQLLGSSAQRPRHKQQRSAVPAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGNNNNNNNNNNNVSSSSSSSAVAQSAASAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQHSSQQQQSSQQQQQQAQSQSQQQQQRRQQHAGGAGAAGPESGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNPNNNSHKTNNNNNNKNNNNNNNEDEMELEDEQLVLSSKQRRLKAVLNNNNIIRDEEHENRADDDSDVDSVDSVAQVITSTPDVATLLASGGTSPSHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEENELEEEEQQQQQHEEDHEQQHKQEEQEQAEQRECEDFFQQLYLKNKSSAALLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCEENKSRTDADILTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAATTSMPQRPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQRDQLERHELLLQQQQQQQQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGFMAPPPPTAASVATAADKSMPTNPTAAAAGATAATIAALPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAHRQRHRSGHHVMRDRAASSSAVQAAAAAQAAAAAAAAMNNLRASNTQQLKARKDTDLLQQALAHGSSSVVTNPLLHFNYNNNSIGNKQQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVEGEGECEDDDDEEEEHEFNVDDEEQEDEEMDLDDEYQQQQLPHEDDDDNDDDNDAAAAKDKLQSKPIEAAKKAAEIIIKENEEKASEKQARCQSQSRGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQLERQKERERELELEREREREQQQLIQQLRQQMAAAAAAVAVAVVTALAHPPAPQPAQSPPGLEASSDLTYKCHLCEFSFGERLQCLEHIKQLHSHEFALLLAKGAIETDAQLQHQQLPVAGGASHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQMLHCSPPSTPTPTNNNNNTCQNNNNNSNNNNNNNSNSKQVLRELLGKANEWRVSRLGEQKENIAEATTTPSAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
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