Dfun009894.1
Basic Information
- Insect
- Drosophila funebris
- Gene Symbol
- Hr39
- Assembly
- GCA_018901825.1
- Location
- JAEIFK010000425.1:18384456-18387760[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.56 4.6e+03 -3.5 0.2 121 158 6 42 3 60 0.74 2 3 0.97 8e+03 -4.3 13.3 47 159 166 286 141 312 0.51 3 3 2.7e-91 2.2e-87 294.0 2.3 1 408 451 846 451 846 0.82
Sequence Information
- Coding Sequence
- ATGCCCAACATGTCGAGCATTAAGACGGAGCAAAATGTGTCTCCAGGAGCCAGTGGTAGCTATCAGTTGCCGATGAACATGTCTACGCCATCCTCGACGCGTCATAATGTCTCCGTGACGAACATCAAGTGTGAGCTAGACGAGCTGCCTACGCCAAATGGGAATCTGGTGCCGGTTATAACCAACTTTAATAATCACAGTCATATTCACAATCATGGTGGAAGCCTGCGTATACCTTTGGGCATGCAGGGTGGCAAGGAAGATGAGTCTGATTCGGAGGCGGAACTGGCCAATATTGAGAATCTGAAGGTGCGACGGCGTGTTGCCGATAAGAATGGGCCGCGACCCATGTCCTGGGAGGGTGAACTTAGTGAGCCCGAGACGGCGGTCGATGAGGAGCTAATGGAAACGGAGACGGTTATCAAGAGTGAGACTAGCAGCGGCCAGGAGGCAGCTATGATGCAGCCTATCAAAACCGAACTGGAGCACATTGCTGGCGAATTGCAGTTACAGCGTCAACAACAACAGGTCCAGCACCAACAACAACATCAAGGGCATCAACAACATCATTTGCAGCCCATCAAACAGAACTTTGCATCCAACAAAGTAAAGCTGGCGCCAACGCAAAGTGATCCCATTAATCTAAAATATGAGCCGACAACATCCACATCACTCTGCGATCGAAGCAAATCCAACAGTGGTGGCCACTTACCACTGCTACCAGCCAATCCCAGTCCAGATTCTGCCATACATTCCGTCTATACGCACAGCAGTCCATCGCAGTCCCCGCTGACATCCCGGCACGCCCCCTACACGCCCTCGCTAAGTCGCAACAACAGCGATGCCTCGCACAGCAGCTGCTATAGCTACAGCTCCGAGTTCAGTCCCACCCATTCACCTATACAGGCACGTCATGCACCTCCTGCGGCGGCCGCTTCCGGTTATGCTAACGGCGGTGGACTGCATCATCATAGCGTACTGTATCGTCCAATCAATGTCGAGGCCTCGGTTGCAGCAGCATCCTCTGTTGGCCAGGAAGCGCAAAATCTCAGCATGGATGCCAGTGGCGGTGCACTGGATTCAACTGCCACGTTGCCCGCATCCCCGGCGGGCATATCTCGCCAGCAGCTTATCAATTCACCATGCCCGATTTGTGGTGATAAGATCAGTGGCTTCCATTACGGTATCTTCTCCTGCGAGTCATGCAAAGGTTTCTTTAAGCGCACAGTTCAGAACCGCAAGAATTATGTCTGCGTCCGAGGTGGTCCCTGCCAAGTGAGCATCTCGACGAGGAAAAAGTGCCCGGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAAGCCATACGCGAGGATCGCACACGTGGTGGTCGTTCCACCTATCAATGCTCTTACACTTTGCCCAATTCTATGCTTAGTCCGCTCCTCAGTCCTGATCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCTCCCTTCCGGTCAGTCCAAGTCTGGGCGCATCAATCAAAACGGAGCAAACGGAGCCGTTAACTAATCATGTTTCGAGAGCTTCAAGCATTCCAGTCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAACTGGCACGTATCAATCAACCGCTGTCCTCATTTGCCACTAGTGGCTCCTCATCGAGCTCTGGTGACGGTTCATGTACAGTTGGGCATAATACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTTTCATCTAATGGCGAGAATGCCAATCCCGATCTGATCGCCCACCTCTGCAATGTCGCCGATCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTCTGCCGCTTTTCAAGAATATCTCGATTGACGATCAGATATGCCTGCTCATTAATTCGTGGTGTGAACTTTTGCTCTTCTCCTGCTGTTTTCGTTCCATTGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAAATAACGCTGGCACAGGCAAAAACCAATGGCTTACAGGCCTGTATTGAGCGCATGTTAAATCTGACGGATCATTTGCGACGCTTACGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGATACTACGGAGCTGCACGAGGCTGTCAAAGTTCGCGAGTGCCAAGAGAAAGCGCTGCAAGGCTTGCAAGCATACACGCTGGCCCACTATCCCGATATGCCGTCCAAATTTGGGGAGTTATTGCTGCGCATACCCGATCTACAGCGCACGTGTCAGCTGGGCAAGGAGATGCTGACGATAAAGACGCGCGATGGTGCCGATTTCAATTTGTTAATGGAATTGCTGCGGGGAGAGCATTGA
- Protein Sequence
- MPNMSSIKTEQNVSPGASGSYQLPMNMSTPSSTRHNVSVTNIKCELDELPTPNGNLVPVITNFNNHSHIHNHGGSLRIPLGMQGGKEDESDSEAELANIENLKVRRRVADKNGPRPMSWEGELSEPETAVDEELMETETVIKSETSSGQEAAMMQPIKTELEHIAGELQLQRQQQQVQHQQQHQGHQQHHLQPIKQNFASNKVKLAPTQSDPINLKYEPTTSTSLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAAAASGYANGGGLHHHSVLYRPINVEASVAAASSVGQEAQNLSMDASGGALDSTATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXSLPVSPSLGASIKTEQTEPLTNHVSRASSIPVLLQEIMDVEHLWQYTDAELARINQPLSSFATSGSSSSSGDGSCTVGHNTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDMPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575636;
- 90% Identity
- iTF_00510595;
- 80% Identity
- iTF_00510595;