Basic Information

Insect: Drosophila fulvimacula
Gene Symbol: ibtk
Assembly: GCA_035045555.1
Location: JAWNOX010000191.1:1687533-1691738[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 7e-08 1.8e-05 24.9 0.0 5 79 553 623 549 672 0.84

2 3 1.5e-15 4e-13 49.5 1.4 5 107 686 792 682 795 0.88

3 3 0.21 54 4.0 0.2 69 109 788 826 781 827 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	7e-08	1.8e-05	24.9	0.0	5	79	553	623	549	672	0.84
2	3	1.5e-15	4e-13	49.5	1.4	5	107	686	792	682	795	0.88
3	3	0.21	54	4.0	0.2	69	109	788	826	781	827	0.79

Sequence Information

Coding Sequence: ATGTCAGCGTTAAGAAACCACGAATATGATTGCACTGCCAAGTGCCGTCAACGTCAACATGGTAATTGCATTACCGCAGCGCTGACCAAGCGCTCCATCGACGATCAGATCTTAGCGACTTTCATAGCCAAAACCTGTGcgaatttttgtaatattccGGACTACTTGGGCCGCTCCGCCGTGCATATGTGTGCTTCCGTGGCACGATATAGAATACTCGAATGGCTATTGAATCAGGGCGCACATGCCAATGAGCGTGATTGGGAATCGGGCTTCACGCCTTTGCATAGAGCTTTGTATTACGGCTCTATTGATTGTGCCGTACTGCTGCTGCGTTACGGCGGCAGCTTGGAGCTGCTGGATGAGGATACACGTTGTCCGCTGCAGGCCATATGCCGGAAATGTGacctgcagcagcaggtcGAATCACAAAACGAAGCGCTCGTCTGGGGCTCCAATAGGAACTATAATCTGGGGATTGGCGATGATCAGAATACATTGACACCACAATCCTTAGATTTCTTTCGCAAGTCAAATCTTTGGCTGGAGCAAGTGGCTCTCGGACCCTTCCACAGTCTTTTTCTGGACAAACGTGGCCAACTCTATGCAGTGGGTCATGGCAAGGGTGGCCGCTTGGGCATTGGTGTGGAGAACAGTCTGCCAGCGCCCAAGCGAGTGAAAGTTCAACTCAAACACAACGAGGATCGCATCATAGGCATCAGCGTCTCGCGCCAACATTCGCTGCTCCTGACCAATCGGTCGTTGGTCTTCGCCTGCGGCTTGAATGATCAACAACAGCTGGGCGTACGGGATGCTGGCGACTATTTGACCACATTCAGGGAGGTAGTTGCTCTGAGGGACAAAGGTGCGAATCAGCTCTTGCGTGTCATTGCCTGCGATCAGCACTCGATTGCCTACAGTGCGAAGGGCGTCTATGTGTGGGGCGCCAACCAGGGACAATTCGGCATTAGCCCCAATACTAAAATCATTGCAGCGCCCACGTTGTTAAAGCTGGCGGAACGGACCTGCATACGCTTCGTGGAGGGAAATAATGCCGCAACTGTTGTCTACACCGAGGAGAAGCTCATACTGCTCTTCTATGCGGATAAACCTAGGACTATAAAGACTCCTAACTATGAGCACTTGAAGAGCATCTCTGTCATGGGCGGTCATATCAAGAACTCCACCAAAGGCTCTGCTGCCGCACTGAAGCTGCTGATGCTAACCGAAACGAATGTGGTCTTTCTTTGGTATGAGAATACGCAACAGTTCTACAGATGCATCTTCTCACCCATTCGCATGCCACAAATCAAGCGCATCTTATACAAGTGCAATCAGGTGCTGCTTCTGTCCATGGACGGCTGCGTTTATCGTGGCAAGTGCCACCAGCTAGCCTTGCCCGCCAGTCCTCAGGAGAAATCAAAGCCCAATTTGGATATTTGGCAAAATAATGATCAGCATCGCACAGAAATCTCCAGGGAACATTACGTTCGCATCGACTTGCAGCGTGTGCCAAATGTGGATCGCGTTGTAGAGATTGTGTGCGATGAGAGCTTCGCCTCGTTTGCTGTGCTTCAGGAATCGCACTTGAAATACTTTCGGAAACCCGCTTTGCCACGGCGTGAGCACAGCCTAAAGAAGCTCTACCATGATACGAGTGAAGCGGATGCTGTGCATGATTTAGTCTTCCATGTGGATGGAGAACGCTTTGCGGCCCATAAGTTTATCATCTTTGTTCGTGCCCCGGGCTTGAGGGAACTCATTCGCGCCTATTTGGATAAGAatgtttatttgaattttcagaATTTAACTGGCAAAATGTTTGAACTGATACTGAAGCATATCTACACGGGTTATTGGCCCACAGAGGATGACATTGACTGCATGCAGCAGAGCTTGGGCCCCAGTAAACCGGCACAGCGCAGTCTCGTCTGTGAAATTTTTCATGCACATCTGCAAAAGTTTCAACTCTATGAGTTGGCCAAATATGTCCACAACTACCTCAGCGAGCAGCAGTTCCCTATGCCTCCTCGGCAACGGTTTTATCGTCTGCAACGCTCACAGTATCCGGAGCTCTACGATGTTCGCATTGTCTGCGAGGATAATCAAGTGCTAGAAGCTCACAAATGCATTCTCGTTGCTCGGCTCGAGTACTTTGAAATGATGTTCATGCACTCGTGGGCCGAGCGCACCACAGTTCACTTCGATGGCGTGCCCTGTGAGTACTTGGAGCCAGTGCTGGATTATCTCTACAGTCTCGATACGGAGTTGTTTTGCAAGCAAAACTATACGGAAACGTTTCTGTATAATATGATAACGCTGTGCGATCAGTACTTCATTGAATCCCTGCAGAATGTGTGCGAATCCTTGATTCTGGATAAGATTAGCATTCGCAAGTGTGGCGAGATGCTGGAATTTGCCACGATGTACAATTGCAAGCTGCTCCAGCAGGGTTGTTTGGATTTCATCTGTCAGAATCTGGCGCGAGTTCTATGCTATCGCAGCATCGAGCAGTGCGAACCAAACACACTGCAACGTATCAATGAGCACTATCGCAAGATGTTTCAAACGGTCTTCGACTATAGACAGATTACGCCGTTTTCCGAAGCGATTGAAGATGAGCTGCTGCTTAGCTATGTGGATGGCTGTGAAGTCGATCTGGATTATCGAGTGGATGCGGACGCCAAGCTCAAGGAGGCTGCCAAGCACAAGCAAAAGGAGCTGCACAACAAGCAGGATGCTCGACATTACGAGCAGCAGGCCATATCCACCATGATGCGTTCGCTGAGTCTAAGTGAATCAACTGGACCAGCACAAGCAGCGGCCACAGCAGCCAACTCCGAGTCAGCACCAAGTGAGACTAAGAATTGGTCCCGCGTTGTGGACAAAAAGGAGCAAAAGCGCAAGCTGGCCGAGACGGCAGTCAAGGTCAACAACGTGCTCAAGCAGGAGGAGCTGCCCTCGCCCGATCTTGTGCCCATATCGCCACGTGCCATGTCCACTAAGGAAGCAACGCCTCCACCGCAGTCAGCTAACAGTTCAGCCGAGTGCAGTACGCCCTTAAGCAAGACCTACAATCTGGACTTAAGTTCCTTAGTGCCGCAGTCCGCTAAGCTGTCGCAGAAGCAACGTAAACGTCTCTCCTCTGAGTCGCAGAGCTGGCGGGCGCCAGTGGAGCTAAACAGCTCCACGCCTGTGGCTGTGCCCAATGCTTGGGGTGTCACTGCCAGCTCACCGACTTCTTCGTATGTTGAGCCGTTTAGCCCACCATCTGCAGCTGCCACGGGCAGCGGCTCAGATCCCACTTCTTTCGCCAACATGATGCGCGGCGGACAGGTGGCCAGTCCAGCCGAGTCCGGCAACAGCTTCTCCCAGATCCTCGCCGACGAGCGCCGTCAACGCGATAGCTTCGAACGCATGCGCAATAAATCGCTCGTTCACACCCAGATAGAGGAGACGGCCATAGCAGAGCTGCGTGAATTCTACAATGTTGACAACATAACCGATGAGACGATTACCATCGACCGCAAGTCGAGGCCCagcaatattaattttaccaCCTGGCTGAAGCATTGA
Protein Sequence: MSALRNHEYDCTAKCRQRQHGNCITAALTKRSIDDQILATFIAKTCANFCNIPDYLGRSAVHMCASVARYRILEWLLNQGAHANERDWESGFTPLHRALYYGSIDCAVLLLRYGGSLELLDEDTRCPLQAICRKCDLQQQVESQNEALVWGSNRNYNLGIGDDQNTLTPQSLDFFRKSNLWLEQVALGPFHSLFLDKRGQLYAVGHGKGGRLGIGVENSLPAPKRVKVQLKHNEDRIIGISVSRQHSLLLTNRSLVFACGLNDQQQLGVRDAGDYLTTFREVVALRDKGANQLLRVIACDQHSIAYSAKGVYVWGANQGQFGISPNTKIIAAPTLLKLAERTCIRFVEGNNAATVVYTEEKLILLFYADKPRTIKTPNYEHLKSISVMGGHIKNSTKGSAAALKLLMLTETNVVFLWYENTQQFYRCIFSPIRMPQIKRILYKCNQVLLLSMDGCVYRGKCHQLALPASPQEKSKPNLDIWQNNDQHRTEISREHYVRIDLQRVPNVDRVVEIVCDESFASFAVLQESHLKYFRKPALPRREHSLKKLYHDTSEADAVHDLVFHVDGERFAAHKFIIFVRAPGLRELIRAYLDKNVYLNFQNLTGKMFELILKHIYTGYWPTEDDIDCMQQSLGPSKPAQRSLVCEIFHAHLQKFQLYELAKYVHNYLSEQQFPMPPRQRFYRLQRSQYPELYDVRIVCEDNQVLEAHKCILVARLEYFEMMFMHSWAERTTVHFDGVPCEYLEPVLDYLYSLDTELFCKQNYTETFLYNMITLCDQYFIESLQNVCESLILDKISIRKCGEMLEFATMYNCKLLQQGCLDFICQNLARVLCYRSIEQCEPNTLQRINEHYRKMFQTVFDYRQITPFSEAIEDELLLSYVDGCEVDLDYRVDADAKLKEAAKHKQKELHNKQDARHYEQQAISTMMRSLSLSESTGPAQAAATAANSESAPSETKNWSRVVDKKEQKRKLAETAVKVNNVLKQEELPSPDLVPISPRAMSTKEATPPPQSANSSAECSTPLSKTYNLDLSSLVPQSAKLSQKQRKRLSSESQSWRAPVELNSSTPVAVPNAWGVTASSPTSSYVEPFSPPSAAATGSGSDPTSFANMMRGGQVASPAESGNSFSQILADERRQRDSFERMRNKSLVHTQIEETAIAELREFYNVDNITDETITIDRKSRPSNINFTTWLKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00546747;
90% Identity: iTF_00493744;
80% Identity: -