Basic Information

Insect: Drosophila formosana
Gene Symbol: ftz-f1
Assembly: GCA_035045625.1
Location: JAWNOW010000173.1:552935-554713[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.21 1.2e+03 -1.5 0.4 122 153 53 83 9 126 0.54

2 3 9.3e-18 5.4e-14 52.4 1.2 1 76 240 311 240 352 0.72

3 3 1.5e-63 8.8e-60 203.2 5.9 120 408 305 590 299 592 0.85

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.21	1.2e+03	-1.5	0.4	122	153	53	83	9	126	0.54
2	3	9.3e-18	5.4e-14	52.4	1.2	1	76	240	311	240	352	0.72
3	3	1.5e-63	8.8e-60	203.2	5.9	120	408	305	590	299	592	0.85

Sequence Information

Coding Sequence: ATGATGGGCTACTATCCGCTGGAGAATATGACTCGAAGGTCTGAGGCGACCCCGGCAAGTTTCCTCAGCTCAACAACAGCTCAATTGCTGGACTTGCAGAGCTTTGAGGCGGTTGCCGTCTGCAGCAAAAGCAATCACGCGGATGCAGCTTTTGCAGTTGCCAATGAGCTGGCCgacacaacatcaacaacaacaacagttgctgccacaacgacgacaacgaacACTGGCAATCGTCACTCATTGCACAGAATCGAGGAGCTGACCGGCAATCTTTGTGCCGAGCCCCAAGCTCATCTCGTTCGTGCTTACCAAAGCTCAGAGGATGACTCCAACTTGGAAGAAGAGTTTGCCCAAGATATTGACGGTCCTCAGACAAATGCAACGCATGCACTGGAGAGTGGCAACATCAAGGGCAGCAAAGGAGTCGCAGCCTGTGATGCCACTCCAGCTCCAGGTGCAGCGATCAATGGCGGAACCCTGGACATGAAACAGCTCTTCGAGGAGCTGTGTCCTGTGTGCGGCGACAAAGTGAGCGGCTACCACTACGGTCTGCTCACCTGCGAGTCCTGCAAGGGGTTCTTCAAGCGCACGGTGCAGAACAAAAAGATCTACACGTGCGTGGCAGAGCGTTCGTGCTACATCGACAAGACGCAGCGCAAACGCTGCCCCTACTGCCGCTTCGAGAAGTGCCTGGAGGTGGGCATGAAGCTGGAGGCGGTGCGCGCGGATCGCATGCGAGGCGGTCGCAACATGTTCGGTCCCATGTACAAGCGGAATCGGGCGCGCAAGCTGCAAGCGATGCGACAGCGTCAATTGGCGCTCCAAGCGCTGCGCAGTTCGGTTGGCTCCGAGAGCCGCCTCGTCAAGCCGACGCACTTCCCATCGATCGTCGAGCAGGCGAATCCAAAGCAGGATATTCAAATAGCGCAAGTCTCGTCGCTCACACCGTGGACAGACGCTGATCCGTCGCCCAGCCCCTTGTTTGGCTCATCCGTCAGCAATGCGGGCTATGCAtttgataacaacaacatgtgTGGAGCACAATCGCTGGGAAGAGCATCGCCCATGATTCGGGGATTCATCGAGGCGCAGTTGATCGATGATCGGGAATGGCAGACGCAGCTGTTTGCGCTCTTGCAGAAGCAGTCGTACAATCAAGTTCAGGTCGATCTGTTTGAGCTAATGTGCAAGGTGCTCGATCAGAATCTGTTCTCGCAGGTCGATTGGGCACGCAACAGCGTCTTCTTCAAGGACCTCCCGGTAGACGATCAGatgaagctgctgcagcactCGTGGTCCGACATGCTTGTGCTGGACCATCTGCATCATCGCATGCACAACGCTCTGCCCGATGAGACGCAGTTGCACAACGGTCAGATGTTCGATCTTTTGGGCCTCGGTGTTCTGGGCGTCTCCCAGTTGCGTGATCACTTCATCGAGCTGCAGCACAAGCTGATGGATCTCAAGTGTGATGTGGGCGAGTATGTGTGCCTGAAGTTCCTCATTCTTTTGAATCCACAGTTCCAAGCTGTCAACATTGCCAACATCAAGACTGTCCAGGAGGGGCACGAGAGTGTCCAAGCAGCGCTGCTCGATCACACGCTTGTCTCTTATCCCTCCATTAATGGCAAGCTCGGCAGACTATTGAATATCATACAGGAAATTCGTGCTCTGGCCTCGCGGGGCCAGGAGTATCTGCTCTCCAAGCACTGCGCTGGCAACGCGCCCACGCAGACGCTGCTCATGGAGATGCTGAACGCTAAGCGGAAGGTGTGA
Protein Sequence: MMGYYPLENMTRRSEATPASFLSSTTAQLLDLQSFEAVAVCSKSNHADAAFAVANELADTTSTTTTVAATTTTTNTGNRHSLHRIEELTGNLCAEPQAHLVRAYQSSEDDSNLEEEFAQDIDGPQTNATHALESGNIKGSKGVAACDATPAPGAAINGGTLDMKQLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKIYTCVAERSCYIDKTQRKRCPYCRFEKCLEVGMKLEAVRADRMRGGRNMFGPMYKRNRARKLQAMRQRQLALQALRSSVGSESRLVKPTHFPSIVEQANPKQDIQIAQVSSLTPWTDADPSPSPLFGSSVSNAGYAFDNNNMCGAQSLGRASPMIRGFIEAQLIDDREWQTQLFALLQKQSYNQVQVDLFELMCKVLDQNLFSQVDWARNSVFFKDLPVDDQMKLLQHSWSDMLVLDHLHHRMHNALPDETQLHNGQMFDLLGLGVLGVSQLRDHFIELQHKLMDLKCDVGEYVCLKFLILLNPQFQAVNIANIKTVQEGHESVQAALLDHTLVSYPSINGKLGRLLNIIQEIRALASRGQEYLLSKHCAGNAPTQTLLMEMLNAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00509154; iTF_00614219; iTF_00614243;
90% Identity: iTF_00509154; iTF_00614219; iTF_00614243;
80% Identity: iTF_00509154;