Basic Information

Insect: Drosophila flavopinicola
Gene Symbol: Hr39
Assembly: GCA_035042425.1
Location: JAWNLL010000454.1:922581-925537[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.28 1.7e+03 -1.9 0.7 139 183 132 176 25 189 0.70

2 3 3 1.8e+04 -8.0 19.0 43 159 180 303 166 344 0.44

3 3 7.6e-98 4.6e-94 316.2 21.2 1 408 468 854 468 854 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.28	1.7e+03	-1.9	0.7	139	183	132	176	25	189	0.70
2	3	3	1.8e+04	-8.0	19.0	43	159	180	303	166	344	0.44
3	3	7.6e-98	4.6e-94	316.2	21.2	1	408	468	854	468	854	0.86

Sequence Information

Coding Sequence: ATGCCCAACATGTCGAGCATTAAGACGGAGCAGAGTGTCTCGCCCGGTGCCAGTGGCAGCTATCAGCTGCCCGTTAACATGTCCACAACGTCAGTGACGCCGACGTCGCAACGTCACAACGTGTCCGTGACGAACATCAAGTGCGAACTGGACGAGTTGCCGACGCCGAATGGCAACCTGGTGCCGGTCATCGCCAACTACAataatcacaatcacaatcacaatctgCGCATACCGCTGGGCGGCAACGAGGACGATTCCGATTCGGAGGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGCCGACGGGCGGCCGACAAGAACGGGCCGCGACCCATGTCCTGGGAGGGTGAGCTCAGCGAGCCCGACACCAACGGCGGCGACGAGGAGCTCATGGAAACGGAGACGGTGATCAAGAGCgaggcgagcagcagcagcagcagcggcagcggggCCACAACACTGGCCAGCAGCCAGGTGAATCATGCTGTCATGCTGCAGCCGATCAAAACCGAACTGGAGCACATAGCCGGcgagatgcagcagcagcagcaactgcagcagctgcaacagcaacaacaacagcagcagcagcaacagcaacaacaattactgccactcaagcagcagcagagctaTGCGCCCAACAATAAACTGAAGCTGGCGCCCACGCAAAGTGATCCCATCAATTTGAAATACGAACCGACGACAGCGTCGCTGCTGTGCGATCGCAGCAAGTCCAGCAGCGGCGGCCacttgccgctgctgcccgcCAATCCCAGTCCCGACTCGGCCATACATTCCGTCTACACGCACAGCAGCCCCTCGCAGTCGCCGCTGACGTCGCGGCACGCCCCCTACACGCCCTCGCTGAGCCGCAATAACAGCGACGCCTCGCACAGCAGctgctacagctacagctccgAGTTCAGTCCCACCCACTCACCCATCCAGGCGCGTCATGCGCCGCCGGCCAGCGTCGCTGCGCTGTTTCCTGGCAATGCGCAAGCAAACGGCGGCAACTCCAGCTATCCGAACGGGCTGCATCATCATAGTGTGCTCTACCGGCCGCTCAATGTGGATGCCGCCCAGGATGCGGCGCAAAATCTCAGCATGGATGCAGCGGATGCGGCGGCCACGTTGCCAGCCTCGCCGGCGGGAATCTCGCGCCAGCAGCTGATCAATTCGCCGTGTCCGATTTGTGGCGACAAGATCAGCGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTGCAGAATCGCAAgaactatgtgtgtgtgcgtggcgGACCGTGCCAGGTGAGCATCTCCACTCGCAAGAAGTGTCCCGCCTGCCGCTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAAGCGATACGCGAGGATCGCACACGTGGCGGTCGCTCCACCTATCAGTGCTCCTACACTCTGCCCAACTCGATGCTCAGTCCCGATCAGGCggcagccgccgcagccgttgtcaatcagcagcagcagcagcatcagcatcagcagcgactccagcagcagcaacagcagcatcagcagcagcatcagcaacaacagcagcagcaacatggcTCACACAATGGCTTTGGTGGCTCCAACTCACTGCCCGCCAGTCCCAGTCTCGGCACATCCATCAAGACGGAGCAAACGGAGCAGCTGAATCATcacacatcatcatcatcatcatcatcatcatcgcgaGCCTCAAGCATTCCAGCACTATTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCCGAACTGGCGCGCATCAATCAGCCGCTGTCCTCATTTGCATCTGGTGGCTCCTCGTCGAGCGCCGCGGGCGGTTCGAGTTCCGCCGGACAGCACACTGCCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCGTCCAACGGCGAGAACGCCAATCCCGATCTGATCGCTCACCTCTGCAATGTGGCCGATCATCGCCTCTACAAGATCGTCAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGTTTGCTCATCAACTCGTGGTGTGAACTGTTGCTATTCTCCTGCTGTTTTCGTTCCATCGATACGCCCGGCGAGATCAAAATGTCACAGGGCAGAAAGATAACGCTGGCACAGGCTAAAACCAATGGCTTACAGGCCTGCATTGAGCGCATGCTGAATCTGACCGATCATTTGCGACGACTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACCACGGAGCTGCATGAGGCGGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGCTCTGCAGGCATACACGCTAGCCCATTATCCCGATACGCCGTCCAAATTTggtgagctgctgctgcgcatacCCGATCTGCAGCGCACGTGTCAGctgggcaaggAAATGCTGACGATCAAAACGCGCGATGGCGcagatttcaatttgctgatGGAACTGCTGCGTGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPVNMSTTSVTPTSQRHNVSVTNIKCELDELPTPNGNLVPVIANYNNHNHNHNLRIPLGGNEDDSDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPDTNGGDEELMETETVIKSEASSSSSSGSGATTLASSQVNHAVMLQPIKTELEHIAGEMQQQQQLQQLQQQQQQQQQQQQQQLLPLKQQQSYAPNNKLKLAPTQSDPINLKYEPTTASLLCDRSKSSSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPASVAALFPGNAQANGGNSSYPNGLHHHSVLYRPLNVDAAQDAAQNLSMDAADAAATLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPDQAAAAAAVVNQQQQQHQHQQRLQQQQQQHQQQHQQQQQQQHGSHNGFGGSNSLPASPSLGTSIKTEQTEQLNHHTSSSSSSSSSRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFASGGSSSSAAGGSSSAGQHTANAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQALQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00508382;
80% Identity: iTF_00508382;