Basic Information

Insect: Drosophila ficusphila
Gene Symbol: -
Assembly: GCA_018152265.1
Location: JAECXK010000775.1:10855560-10860459[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00015 0.01 16.1 1.2 1 23 166 189 166 189 0.96

2 14 0.0015 0.11 12.9 3.1 2 23 238 260 234 260 0.90

3 14 0.0065 0.46 10.9 0.8 1 23 354 377 354 377 0.93

4 14 0.092 6.6 7.3 3.0 2 23 426 448 425 449 0.93

5 14 0.00059 0.042 14.2 0.4 1 23 516 539 516 539 0.92

6 14 2.5 1.8e+02 2.7 0.0 2 14 558 570 557 582 0.85

7 14 0.0012 0.082 13.2 5.6 2 23 590 611 590 612 0.95

8 14 0.041 2.9 8.4 0.0 1 20 703 722 703 724 0.95

9 14 0.00096 0.068 13.5 0.2 1 23 755 778 755 778 0.93

10 14 0.0021 0.15 12.5 1.5 2 23 828 850 827 850 0.95

11 14 0.016 1.1 9.7 1.8 1 23 942 965 942 965 0.91

12 14 0.025 1.8 9.0 1.2 1 21 1017 1037 1017 1038 0.95

13 14 1.9 1.4e+02 3.1 0.2 3 14 1070 1081 1068 1093 0.72

14 14 4.2 3e+02 2.0 0.1 1 10 1111 1120 1111 1127 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00015	0.01	16.1	1.2	1	23	166	189	166	189	0.96
2	14	0.0015	0.11	12.9	3.1	2	23	238	260	234	260	0.90
3	14	0.0065	0.46	10.9	0.8	1	23	354	377	354	377	0.93
4	14	0.092	6.6	7.3	3.0	2	23	426	448	425	449	0.93
5	14	0.00059	0.042	14.2	0.4	1	23	516	539	516	539	0.92
6	14	2.5	1.8e+02	2.7	0.0	2	14	558	570	557	582	0.85
7	14	0.0012	0.082	13.2	5.6	2	23	590	611	590	612	0.95
8	14	0.041	2.9	8.4	0.0	1	20	703	722	703	724	0.95
9	14	0.00096	0.068	13.5	0.2	1	23	755	778	755	778	0.93
10	14	0.0021	0.15	12.5	1.5	2	23	828	850	827	850	0.95
11	14	0.016	1.1	9.7	1.8	1	23	942	965	942	965	0.91
12	14	0.025	1.8	9.0	1.2	1	21	1017	1037	1017	1038	0.95
13	14	1.9	1.4e+02	3.1	0.2	3	14	1070	1081	1068	1093	0.72
14	14	4.2	3e+02	2.0	0.1	1	10	1111	1120	1111	1127	0.79

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTGTGGACATCGATGTTCTCCTCGGACTTCGAAGAGGGTGAACCGGAGACTGGGGAGGCGGAACTGGAAGAGAGCGAGCAGTATGGCAATGACAACGACGATTTTCCTGGGGATTCAGAGATCCTGGAAGCAGGTGACGCCATTGATGACCTGCTGGATGGTGAAGAGGGTGACAGGGAGGAGGAGGAGGAGGACTATGGCGACGGCAGCAAGGGAGCAAAACCTCTCGATCCAGATGACGATGCCCTCTTTGACTTCGATATGGAGCCAATCGTAAACATTGCAGAGACACAGCCATCGGTTCTAACTCCTGCTGGACCAATGGCCCCCCAAGTGCGTCCTCCCATGCAGCGTCACTCTGTTCCCGGTTCTCAGGGTCGTCCTAGATTAAATCCCGGACTCTCTATACGCCCCACGACCTCGCAGATAAATGCCACCGATGAGAATGGGGTTCCCATTAACTATGAGCTGGGTGTGGTCTACATTTGCCCCGCTTGTGGTGGAGAGTTCCGACAACAGGACCACTGGAAGCGGCACATGAACCACATTCACAAGTACAACACATTGAGGGGCCTCAATTTCACGCCGCTGGACAAGCTCTATCAGCGTTGCAAGGAGTGCAACAAGCGGATTGCCATGCACAGCCGGGAAAACCTGCTGAAGCACAAGTTCACGCACCTGCCCTTCAGGTGCACCAAGTGCTACATCTGCAAGAGGGAGTACAAATACAGGCAAGATCTTATGGTGCATCTGCGTATGGTTCATTGCGATGAAGTGGTGGCCATGATGCGTGAGGGATACAATGCTGCAGGTCGCAAGACACGGGTTCGGGAATCGCGCGTTGAGCAGATGCAGCGGGAGAAGAGCTTTCACGAGGAAAACGACTTCACTGAAGACTTGGATCGCGTAGAGGTGCGAAACGAGGTGCTCGAGCCGGACGCCGATGAGCTTGGTATCCTCGAGCAACCGTTTCCGCAGGAGGTTGCCAAGAAAAAGTCGACTGGCATGCGAGGTGCAGCCGAGCTGTGCGAGGATTACATCCACTACATGTGCCCCGACTGCGGAACCGAATGCGATACCCACGCTCAGTGGAGCCAGCACATCGAATTTGTTCACGACTACGTCAGTCGACGAGGGCTTAACTTTCGGAGCGTAGACATGCAAATGCAGTGCCTCGAGTGCAAAAAGATTGTAATCCCCAACACCATCAAATCACTACGCGCCCACAAGTTCAGCCATTTATCTCAGCCTGAGTGGCTGCGCTGCAAACTCTGCTACAAGGGCTACACGGATCATCAGGAAGTTATAAGGCATCTGCTGCAAACGCACCATATGAACTCGCTGCTGTCCGAAGACGCAGAGGAGGAGGATCCGGCAGTGACCGTAATAATGGAGGATGAAGACGTCGAGGACAATGGAAATGGCGAGGGAAACGGCACCTTATTGGACGAGGATTCGCCCTACTTTGAAGATGCTCCCCGACGTGGCGGTCGCATCAGCAGCGACGACATTTACGAGCCCCACATCGACTACCTTTGTCCGCAGTGTGGCAAGGAGTTCATCGAGAAGAAGCATTGGCGCACCCACGTAGTGATGGCGCACAACATGAACGATCTGTCCAAGCTGAACTTCGCGATGATCAACGAGCGGCAGCTGCAGTGCACCGAGTGCGAGAAGGTCATTACGAATGCCTATGGAATCCAGAATGCCCAGCAGCACAGGATCACGCATCTTCCATTCAAGGCGTACGCCAGGTGTCGCAAGTGCCACAAGTCCTACACGGACAGGAAGGGTCTCGTCAAGCATCTTGCCACCCATCATCGTGTTGGTTGCGGGCCACGAAAGTCCGCTGGCGGTTCCGCTGGCCCTGCTTCGATGCCCACGCCTCCCAAGCAGCCGCGTAGGCAAATTGTGACTGTGGCCAATGAAACGTACGAGATTATTTACCTAGACGACGTGGAGCAAAGCGGCATGGAGGATGAAAACGACATTGGTGAGCAAATGCAAGCGGAAGAGGAGGACTATCCGATTGCACTGCCTGAACCACCACCACCGCCGCCGCCATCAACCTCGCAAGCATCGCATCATCGCTACAAATGCGTCCACTGCGGCTCACTCTTTCCCACTCAGGCGGCTGTGCGCGTTCACATCAGCGAGAAACGTTGTAGGAAGACTATGGGCAGAAGGCATCGACAGGCCGTGGCCAACGCAGACCCATCCGCTGCCACTGTGGAACAGAACTACATCTTTCTGTGCCCCTCCTGCGGCATGGAGTACAAGACGCAGTTCGAGTGGCGTCGTCACATCAACGAGGTGCACAACTTTGACAAGCGGCAGTATCTTAATATGCGGCAGTTGGACAAGTATCGCTACCAGTGCACCCAATGCAAGGACATTGTGTGCAACTCGAAGCTGAAGGGCCTGCAGGACCATCACTTCCGCCACCTACCATACAGACTGTATCTCAAGTGCCTGATCTGCGGCACCTGCTACAATCACAAGCCGAACATAGCTGCCCATTTGAGAGCCCGCCACAGCATCTACGACAGGGAAAACCCGTTGAAGATCGCCAAGCCGAAGCATGCATTCGGTCGCTACAAGGAAGGGAGTAGGGAAAAGCCAAGAGTGCCCACACCGCCACAGGCAGCGCCCTCTCCGCCGGGATGCTCTTCCTCTGCTGCATCCGCTGCGAGTAGTCAACGCTCCCTTAAACCGCAGCCCGGCGGTCTGCCAACCCGACCTGCCGGTCTGAACACCCTGGAGGACAGCATCTCGTATCACAATGCCGTGGATCTGGACTTCATCACGTACTTCTGCCCCAAGTGTAACCAGAACTTTGACTCGCACGCCTTCTGGCGCAAACACATCGTGGAACAGCACAACTTTAATAGCCGCGAGGGTCTGAACTTCCGGCAGATCGACAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGGGTGACTGTGACCCACACCAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGCCATCTGCCACATCGCTCCTTCAAGTGTTTAACCTGCGATGGCGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCATCTCAACCGCGACACCAATCGTTGTGACAATCGACCGCACCGGGACTTGGAGGAAGATGATCCCGATCAGGAGCCAAGTCTGCGTTCCATCTACCAATTGGCGTGTCCGCAGTGCGGCGATAACTTTACAACCCGCAGCATGAAGCAGTGGCGCGAGCACATCAACGACTACCATGGTCTTACCAAGCTGAATCTCCTGCACATGACCAAGATTGGCGAAGATCTCTACCGCTGCCAGGACTGCAACGAGGAGCTTCAGACGAGCAGGCAGTGGGTGCTGCAGTTCCATCGTATTCAGCACCTGCCGCACGCGGCTTACATCCGATGCAAACTGTGCAAGAAGAGCAGTGAAGCGGTTGGAACATCGGCGGGCGAATTGCACAGCCTGCGAGAGCTGCAGCAACATCTCCGTAAACACCATCCTGCGCTGGGCGAAAGCGAAATGGCATTACTGCGCGACCAGATCATCCTGGAGGAGAAGGAGCAGGAGGAGGCCGCCGAGGTGCCCGCTGAGGAGGAAGAAAACCAGGCTGGCCAGGAATCGGGACCCTATATGCCGCTGCCACCGCATTTGCTGGACGAGAGCGACGACGTAGAGTTCGAGGACCAGTATCTGCTGGGCTGA
Protein Sequence: MEGMDLWTSMFSSDFEEGEPETGEAELEESEQYGNDNDDFPGDSEILEAGDAIDDLLDGEEGDREEEEEDYGDGSKGAKPLDPDDDALFDFDMEPIVNIAETQPSVLTPAGPMAPQVRPPMQRHSVPGSQGRPRLNPGLSIRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCKECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRVEQMQREKSFHEENDFTEDLDRVEVRNEVLEPDADELGILEQPFPQEVAKKKSTGMRGAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVIPNTIKSLRAHKFSHLSQPEWLRCKLCYKGYTDHQEVIRHLLQTHHMNSLLSEDAEEEDPAVTVIMEDEDVEDNGNGEGNGTLLDEDSPYFEDAPRRGGRISSDDIYEPHIDYLCPQCGKEFIEKKHWRTHVVMAHNMNDLSKLNFAMINERQLQCTECEKVITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATHHRVGCGPRKSAGGSAGPASMPTPPKQPRRQIVTVANETYEIIYLDDVEQSGMEDENDIGEQMQAEEEDYPIALPEPPPPPPPSTSQASHHRYKCVHCGSLFPTQAAVRVHISEKRCRKTMGRRHRQAVANADPSAATVEQNYIFLCPSCGMEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIYDRENPLKIAKPKHAFGRYKEGSREKPRVPTPPQAAPSPPGCSSSAASAASSQRSLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPHRDLEEDDPDQEPSLRSIYQLACPQCGDNFTTRSMKQWREHINDYHGLTKLNLLHMTKIGEDLYRCQDCNEELQTSRQWVLQFHRIQHLPHAAYIRCKLCKKSSEAVGTSAGELHSLRELQQHLRKHHPALGESEMALLRDQIILEEKEQEEAAEVPAEEEENQAGQESGPYMPLPPHLLDESDDVEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486896;
90% Identity: -
80% Identity: -