Basic Information

Insect: Drosophila ficusphila
Gene Symbol: zfh1
Assembly: GCA_018152265.1
Location: JAECXK010000775.1:17037302-17043041[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 3.5e-05 0.0025 18.0 1.1 1 23 140 162 140 162 0.97

2 15 0.0017 0.12 12.8 1.1 3 23 170 190 168 190 0.94

3 15 0.00024 0.017 15.4 0.2 1 23 341 363 341 363 0.98

4 15 0.00012 0.0082 16.4 0.7 1 23 369 391 369 391 0.98

5 15 1e-05 0.00072 19.7 2.0 1 23 422 444 422 444 0.97

6 15 0.005 0.35 11.3 1.2 1 23 474 496 474 496 0.93

7 15 0.0095 0.68 10.4 1.3 1 23 502 525 502 525 0.97

8 15 0.023 1.7 9.1 0.4 3 19 534 550 533 551 0.95

9 15 0.00014 0.0098 16.2 5.6 1 23 560 582 560 582 0.97

10 15 0.041 2.9 8.4 0.4 2 23 588 609 587 609 0.96

11 15 8.1e-06 0.00058 20.0 1.0 1 23 618 640 618 640 0.98

12 15 0.00092 0.065 13.6 0.1 3 23 648 668 646 668 0.97

13 15 4.9e-05 0.0035 17.6 0.5 1 23 674 696 674 697 0.95

14 15 0.033 2.3 8.7 0.3 1 23 707 729 707 729 0.97

15 15 0.0049 0.34 11.3 0.2 1 23 1260 1282 1260 1282 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	3.5e-05	0.0025	18.0	1.1	1	23	140	162	140	162	0.97
2	15	0.0017	0.12	12.8	1.1	3	23	170	190	168	190	0.94
3	15	0.00024	0.017	15.4	0.2	1	23	341	363	341	363	0.98
4	15	0.00012	0.0082	16.4	0.7	1	23	369	391	369	391	0.98
5	15	1e-05	0.00072	19.7	2.0	1	23	422	444	422	444	0.97
6	15	0.005	0.35	11.3	1.2	1	23	474	496	474	496	0.93
7	15	0.0095	0.68	10.4	1.3	1	23	502	525	502	525	0.97
8	15	0.023	1.7	9.1	0.4	3	19	534	550	533	551	0.95
9	15	0.00014	0.0098	16.2	5.6	1	23	560	582	560	582	0.97
10	15	0.041	2.9	8.4	0.4	2	23	588	609	587	609	0.96
11	15	8.1e-06	0.00058	20.0	1.0	1	23	618	640	618	640	0.98
12	15	0.00092	0.065	13.6	0.1	3	23	648	668	646	668	0.97
13	15	4.9e-05	0.0035	17.6	0.5	1	23	674	696	674	697	0.95
14	15	0.033	2.3	8.7	0.3	1	23	707	729	707	729	0.97
15	15	0.0049	0.34	11.3	0.2	1	23	1260	1282	1260	1282	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGCGGTATGGCGGCATTCAGTGGATACAGCACCACGTCTCCGCTGGGGATTCCTCCGAGGTGGACATCCTGGAGAGCGATGGTGCAACGGGAGCGACAGGCGAGGATCTGGACCATATGGCAGCCGAGAATCTGATATTTATGGCGCGTGACGGTCAGCTGAGCGAGATAATGGCGGCCAACGAGGCGGGCGGAACGGTTCTGGTCACTGCCGACGGGACAACGGTGGCATACGCCGAATCCTTCGATGACGACGCCCAAGTGGTCACCGAGGAAGTTATCACGGACGACTGGGTTCAGCACCAAGGAGCTGAACGTGTGGAAATCGCCGCCGAGCAGATAGCCGGTATAAGCAGCTCGCAGGAATTGCTGGACATGGAGCAGGATGAGTACACCGCGCTGAGACCCTATCCCTGCGACTTTTGCAGCCGTCGCTTTCGAAAGAAGGCCACCTTAAACAACCATATGTTGGCTCATCAGAACGATCGACCGCATCTCTGTAAGCTGTGCGGAGCACGATTCTCGCGTCGTCCGGAGCTCATCAGTCATTTTAAGGCCCACGCAGAGGCCCAGGATGCAGCCGATGCCGAGGCAGCAGCAGCCGCAGCAGATTCCTCCTCATCCATTAAGTTTGAGCACCAGTCGCAGCGGCAATTCGATGATCACTACTACGAACAGGAGTACCAGCTCTACCAGCAGGAACAGGAACAAGCCCAGGAGCAGGAGTTGCAGCAACAGCGACATCAGGTCGTGGAGGAGGGCGAGGTTCAACTCGTGGCCAGCTACCCGGCGGTTGCACAGCCCGCAGCTCCGACACGAGGTAGAATAAGTCGGTTGAAGCCCAAGGAGGAAAGTAGCCAGTTTATAGTTATTTCGGACAAGCCGACTGCCAGTGAGTTGAGGGACTACATGGACACGGAGCCGACTCAGCCTGTGGTCAGCACGTCACAACCAGTTGCCGTCGAGCCTCCTCCTCAGCCGAATTTCCCAGTGCTGGACGACAGTAAACCTTTCGTGTGCCAACAGTGCGGATTGGCCTTTGCGCGGGAAAAAGCACTCGTCTCACATACAAAGAATCACCGCGTGGACTCGCCATTCGAATGCAACCAGTGCCAGGAAATGTTCTGGGATAACAGTAGCCTGCAGGAGCACCAAAAGACGCACCAATTCGAGGAGAGCAACTCTGAGTACGATCCTGCGTCAGCGGAGGATAGCGCCAGCGAATCGGAGCCAGAGGAGCAGTTGTACGGAGAATTCTATTGCAACGAGTGCGGAATCTCTTTCCATCGTCAAGATCTACTGCGGCGACATGCCAAGCTGCACTATAAGCAAACGGATCAGGCGCCGGGAGAAGGCAATTCCGAAGTCACTGCTGGCGGAGATGTGGAGCTTGTCAAAGATTCAAGCGGTCACTGTTGCAACACGTGCGGCAAGTCCTTTCCCAGCGCTTTAGAGATGCTCTCTCATGCTGAGATCCACGCTCGGTTTCCGGCCTTTAAGTGCGTCCTGTGTGGAATCAGCTTTTACGAGGAACAGGCAATCAAGCGGCACCTTCACACCCGCCACCCCAGCGAACTAAAGACCAATTCCTGCGTACTTTGCGGCAAGGAGTGCCGCGACCGAAAAGCCCTGATAAAGCACGCTTGGGACCATTCCCGCGAGAAATGCCATTCGTGCTCCAAGTGCGGCAAGAACTTCCACAATAAGGCGCGTCTAAAGCGGCACATGGCCTCGCACCGCGACAAGTCGGTGGTGTGCGAGGTGTGTCAGGAAGAGTTCCCCGACGGACGGACGCTCTCCAACCACCGCCACTCCCACAGCACCACCTCACCGGGCAAACTGTTCCCGTGCCATGAGTGCGGTAAGACGTTCGGGTCGCGTAGCTCACAGCAGATCCACGTGCGCATCCACACGGGCGAGCGTCCCTACGGCTGTCGCTACTGCTGGAAAGCCTTTGCCGATGGCGGCACTCTGCGCAAGCATGAGAGAATACATACGGGGGAGAAACCTTATGCCTGCTCAGTCTGTCCTCGCGCCTTCAATCAGCGGGTGGTGTTGCGCGAGCACATACGCTCCCATCATTCTGGACTGGATGTGGCGCGGAATACGTACCACTGCACGGTCTGTTCCGAGGATCTGGCATCGTCTAACGACCTTATCCAGCACCTCATCCAACACAGTGACTCAAACACAGCCAAACAGCGTCAGCCCGTTACGGGGCCGCGTAAATACAAGAGGCGCCGCAAACTGCAGCCGCATGAAATCGCCCATATGCGTGCGGAGCACAAAGGCGCCAACGAGGAAGAGGAGGAGGAGGAGTCCACGCGAAAAGGCGATGCAGATGAGTACGCCAGTGACATCGATCTTTGCGACTTTGCTGTGGACGATCTCTTTGACATGGCAGAGTCGCCGAAAAAGGAGAAGCGAAAAAGAGCCGCTGCAGCTCCAAAATCTGAAGCTAAGCCCGTGACCAATGGCAAATCGACAAAGCCTGTTCAAGAAAAGAACAAGGTGAAACCGAGATACGACTCCACCAGTAGCCAGCAATCGGATCGCATTTGGGAGGAAAAGTTTCTGCACGACAGCCAAGTGGCGCTTTTCCAGATCGATTCTCTGGTGGTGGTCAACGATACTCATCTCCAGCCCGCCACTTCCGCTGCATCCTCAGCGATGCCCAATACGAGGGGTGCGGCCAAGCAACAAGGAAAAGCGCTGACGAAACCTGCAGAGCAGGGATCAGGAAATTTCAATTCAACCGAAGCGCCAAGCGTTTCCACATCCTCCGCCACCAACTCTTCTTCCAGTTGTCGTAGTAGGAAGAAGGCAGGAACCAGCAAGACTGTCAACAAAGCACCACCTGCCAGCAGTTCGCGTCCTCGTATGATTCACACGGAGAAGGCTAAGGTGCCTAAGGGAAACGCCACAGAATCCTCCAGTAGTGCGAGCAAGAAGACGCGGTCAAAAACCTACATCAGTCGCACGGAGACGACCAATCTGGGCTTGGATAAGACCCGCAGCAGTGCCTCTAACATGGTCGATGACTATGAGATCATTTCCCCGGCCACCCATCCACCAAATCAGATCAGCTCCAGTCCCTTGCACATAAAACAGGAGCAGGAGCAACAGCAGCGTGTCCAACTGATGTACGACGACAATCTCTTGATAGACGCTGGTCTGCTGAGGGAGAAGACGTACGAGAAGTTTGACCCGAGCATTGTCAACGATCTGGAGGAGATTTTGCGCTCGCCACTCAAGCACGAGAGAAATTCCCGCCTGCGCTTTACTAGCGAATCTTCGACCACGCCGCAGTTTCTTCCCGAAGAGGAACAAAACCTGATCAAAATCGAGCCAACGTCTCCAGATTTGCGGGAAATGGTGGAGAGTCAGCAGAGAGTAACAGCTCCTACTGGTAACACTCCTTCATCCTCCTCTTCTGCCAGAACTTCCAGACATCTGCGACAGATCACTGCCAATGGTACCAGGGCAGGAAGCAAGAGATCGGCGGGAGGAGCTCCGACAAAATCCTCAGCGAACTCGGGAGTGGCTGCCAAAAAAGCGAGCACTGCCACCAAGGTCGGGGGCAGCAGTTCATCCTCGTACCTCGGCTACGGGGTGGACGCCTATAATGTAAACGGTGCTGCTAGTGCCAGCACTGCCGATGTGGGCGGCGGATTCTTTTCCATCTCGGAAGTTGTTTCCGCTGCCGATGCTGCGGACGCGGCGGCCAAAGCGGCGGCGGCTGGTAAATCGGAACGGAAAAGCCGCAGCTTCGAGTGCGAAATGTGCTCGGCGATCTTCTATGATCGCGCCCAACTGCTGGAACATGTACACATTCATATTTGA
Protein Sequence: MNNQRYGGIQWIQHHVSAGDSSEVDILESDGATGATGEDLDHMAAENLIFMARDGQLSEIMAANEAGGTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKATLNNHMLAHQNDRPHLCKLCGARFSRRPELISHFKAHAEAQDAADAEAAAAAADSSSSIKFEHQSQRQFDDHYYEQEYQLYQQEQEQAQEQELQQQRHQVVEEGEVQLVASYPAVAQPAAPTRGRISRLKPKEESSQFIVISDKPTASELRDYMDTEPTQPVVSTSQPVAVEPPPQPNFPVLDDSKPFVCQQCGLAFAREKALVSHTKNHRVDSPFECNQCQEMFWDNSSLQEHQKTHQFEESNSEYDPASAEDSASESEPEEQLYGEFYCNECGISFHRQDLLRRHAKLHYKQTDQAPGEGNSEVTAGGDVELVKDSSGHCCNTCGKSFPSALEMLSHAEIHARFPAFKCVLCGISFYEEQAIKRHLHTRHPSELKTNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVARNTYHCTVCSEDLASSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAEHKGANEEEEEEESTRKGDADEYASDIDLCDFAVDDLFDMAESPKKEKRKRAAAAPKSEAKPVTNGKSTKPVQEKNKVKPRYDSTSSQQSDRIWEEKFLHDSQVALFQIDSLVVVNDTHLQPATSAASSAMPNTRGAAKQQGKALTKPAEQGSGNFNSTEAPSVSTSSATNSSSSCRSRKKAGTSKTVNKAPPASSSRPRMIHTEKAKVPKGNATESSSSASKKTRSKTYISRTETTNLGLDKTRSSASNMVDDYEIISPATHPPNQISSSPLHIKQEQEQQQRVQLMYDDNLLIDAGLLREKTYEKFDPSIVNDLEEILRSPLKHERNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVTAPTGNTPSSSSSARTSRHLRQITANGTRAGSKRSAGGAPTKSSANSGVAAKKASTATKVGGSSSSSYLGYGVDAYNVNGAASASTADVGGGFFSISEVVSAADAADAAAKAAAAGKSERKSRSFECEMCSAIFYDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605719;
90% Identity: -
80% Identity: -