Basic Information

Insect: Drosophila falleni
Gene Symbol: grau
Assembly: GCA_035045575.1
Location: JAWNOV010000011.1:3612557-3614604[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.025 1.9 9.3 1.1 6 23 290 307 290 307 0.98

2 9 5.3e-05 0.004 17.7 2.9 1 23 313 336 313 336 0.93

3 9 0.00016 0.012 16.1 2.3 1 23 344 366 344 366 0.97

4 9 0.00022 0.016 15.8 0.4 2 23 372 394 371 394 0.96

5 9 0.1 7.5 7.4 0.1 2 23 400 421 399 421 0.95

6 9 3 2.3e+02 2.7 3.9 2 23 430 451 429 451 0.90

7 9 0.0001 0.0075 16.8 0.2 2 23 459 481 458 481 0.96

8 9 8.9e-06 0.00067 20.1 0.6 3 23 489 509 488 509 0.99

9 9 0.00064 0.048 14.3 8.5 1 23 515 538 515 538 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.025	1.9	9.3	1.1	6	23	290	307	290	307	0.98
2	9	5.3e-05	0.004	17.7	2.9	1	23	313	336	313	336	0.93
3	9	0.00016	0.012	16.1	2.3	1	23	344	366	344	366	0.97
4	9	0.00022	0.016	15.8	0.4	2	23	372	394	371	394	0.96
5	9	0.1	7.5	7.4	0.1	2	23	400	421	399	421	0.95
6	9	3	2.3e+02	2.7	3.9	2	23	430	451	429	451	0.90
7	9	0.0001	0.0075	16.8	0.2	2	23	459	481	458	481	0.96
8	9	8.9e-06	0.00067	20.1	0.6	3	23	489	509	488	509	0.99
9	9	0.00064	0.048	14.3	8.5	1	23	515	538	515	538	0.98

Sequence Information

Coding Sequence: ATGATTTGCCGTCTGTGCCTAAACAGCGCCAACGACACCATTCAAATATTTGAGGGCGTTGGCTTGTCCCTAAACGTTGCCACGGTGCTAgccaaatatttttggtttcagCCCAAAAACGATGATCCAATATCGACTGCCATTTGTGTGGGCTGCTGGACGCATGTGAGCGACTTTAACGAGTTTTACTGCAGCGTGGAGAAGGCGCATCGTCTGCTCACCGAAAGATTCTCTTTAAAAGGCGGCGAGCAACAGGAGAGGATTAACAAGAGTGCGACAGGAGAAGCACATAAGGATGACCACTCTGAGCATTCAAAAGAGTTTCTAGATAACAGCGAAGGTGACGACGGCTTGGAACAGGACAATGACAATGCCGTCGAGGATTTATATGACAGTGAGAGTGAAGCAGCTGCATCCTTTAGCAATGAGCAATTTCTCAACGAGGTGCTGACCCAGCAGACAGCTGATGATTCCACTCCAGTTACTGAGCCACCTAATGAGCCGGAAGATGTCGTTGTCAAGCAGGAAATCGGAGTTGTAGCTGTGCAGGAACGTCGAGAGACACGAGCCACACGAGCCAAAAGCAAAGCGAATCAATTGCTCGCACCTGAATCTCCGCCAGCTGAAAAAGCCACATCCGCCAGGCGCAGGGGCAGATCAAAGTCGGAGAAACATGACGTCACTGTCGAGGAGAGAGCAAAGAGCAAACGCTATGTGGATTACAAGAAGTCCATGTGGGAGATTGATGAGAAGATAGCGCAACATATGCGACTCACCTGTGCCATTTGCCACGAGGGCCAGGAGACGTTCCTGTTGCTCTGCAAGCACATGCAGCAGGTGCATCATCGCAAGGGTTATGCCATCTGCTGCAACAAGAAGTTCTACAAGCGATCCTTTCTCACCGATCACATCGATCGGCATAACAATCCTGAGAAATTTAAATGCAATCTCTGTGGCAGAACCTTTGCGGATAAACAGTGTTTGCGCAATCATGAGCTGCTCAAGCATCAGCCCGATGAGGAGAAGACATTCATGTGCGAGCACTGCCCAAAGAGATATACCAAGCAGTATTTATTGGATCAGCATCGGATTATACACAAGGAACGCAATGTTCCCTGCGATCTGTGTGACAGGCGATTCCCCAACGTTTCCATGCTCTGTACGCATGTAAAAATGGTGCACGGCAATTATGGCACAATGTGCGATATTTGTGCCCAGGTGATAAGAGGACAGGCGGCGTTTCAGCGTCATCAGCTGGAGCACGCTGGCATCACGGAGCCCAAGGTGCAGTGTGATATTTGCGGATCGTGGCACAAGAACAAATACAGTTTGAAGAAGCATGTGAGTCGACACAACGGCTCCTCGGAGGCGAGCACCTGCAACATCTGTGGCAAGGTGTCGCCCAATCGCAGCGCCATGTTGAGTCATCAGCGTTATGTGCACACTGCGGATCGTGTCCATGGCTGCAGTGTGTGCAACAAGAAGTTCAAAAAGGCCATCAATCTCAAGGAGCACATGGCCACACACACGGGCGAAGTGCTGTACAAGTGTCCACACTGTCCCAAGACCTTCAACTCGAATGCCAATCAGCATTCGCATAGGAAGAAGTGTCATCCCAAGGAGTTTGAGGAGGCGCGTAAGGCGCGTCTACAAAAACGCATGGCGCCCAGTGCAGGTGAAAGCAAATCCAAGGCAAACATGATAACAATTACAACGTCAGGAGAGACAGATGGGGAGATGGAGACACACAACATTCTGGTGACGACAGCGGAGCAAAGCGATGAAGAGGAATTCAAAGGCGAGGACATTGAGTTTATGCTCACCCTCAGTCCACAGCCAACGGAGTGA
Protein Sequence: MICRLCLNSANDTIQIFEGVGLSLNVATVLAKYFWFQPKNDDPISTAICVGCWTHVSDFNEFYCSVEKAHRLLTERFSLKGGEQQERINKSATGEAHKDDHSEHSKEFLDNSEGDDGLEQDNDNAVEDLYDSESEAAASFSNEQFLNEVLTQQTADDSTPVTEPPNEPEDVVVKQEIGVVAVQERRETRATRAKSKANQLLAPESPPAEKATSARRRGRSKSEKHDVTVEERAKSKRYVDYKKSMWEIDEKIAQHMRLTCAICHEGQETFLLLCKHMQQVHHRKGYAICCNKKFYKRSFLTDHIDRHNNPEKFKCNLCGRTFADKQCLRNHELLKHQPDEEKTFMCEHCPKRYTKQYLLDQHRIIHKERNVPCDLCDRRFPNVSMLCTHVKMVHGNYGTMCDICAQVIRGQAAFQRHQLEHAGITEPKVQCDICGSWHKNKYSLKKHVSRHNGSSEASTCNICGKVSPNRSAMLSHQRYVHTADRVHGCSVCNKKFKKAINLKEHMATHTGEVLYKCPHCPKTFNSNANQHSHRKKCHPKEFEEARKARLQKRMAPSAGESKSKANMITITTSGETDGEMETHNILVTTAEQSDEEEFKGEDIEFMLTLSPQPTE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00602095;
90% Identity: iTF_00586209;
80% Identity: -