Dfal008144.1
Basic Information
- Insect
- Drosophila falleni
- Gene Symbol
- rdx
- Assembly
- GCA_035045575.1
- Location
- JAWNOV010000062.1:25675941-25681219[-]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 1.6e-28 3.9e-26 91.5 0.1 6 109 3 105 1 106 0.94 2 4 1.5e-27 3.6e-25 88.4 0.0 7 109 109 210 104 211 0.94 3 4 9.7e-28 2.3e-25 89.0 0.1 7 109 214 315 209 316 0.94 4 4 0.023 5.5 7.3 0.0 80 109 318 347 313 348 0.86
Sequence Information
- Coding Sequence
- ATGCTAAACACAAAGGAATTGGCCGATGTGACAATCGTCACAAGTGACGGCCATAAGATACCGGCTCATAAGTTCGTATTATCAGcACGCAGCAAAGTCTTTGCGGCCATGTTCAAGCATCCATTTAAGGAAAATAGAGATAATTGTGTTGATATTAGCGAATTTAGTTTCGCTGTTGTCACGGAACTGCTACAATTCATGTACACGGGGGAAGCACCTAAATTGGGAGATATGCCAGTAGATCTACTGGCGGCAGCTGACAAGTACCAGCTCGATAGACTTAAGGCGCTGTGTGCCAAGTCCATGAGGGATAATCTATCCATAGAAACTGAATTGGCCGATGTGACAATCATCACAAGTGACGGCCATAAGATACCGGCTCATAAGTTCGTATTATCAGcACGCAGCAAAGTCTTTGCGGCCATGTTCAAGCATCCATTTAAGGAAAATGGAGATAATTGTGTTGATATTAGCGAATTTAGTTTCGCTGTTGTCACGGAACTGCTACAATTCATGTACACGGGGGAAGCACCTAAATTGGGAGATATGCCAGTAGATCTACTGGCGGCAGCTGACAAGTACCAGCTCGATAGACTTAAGGCGCTGTGTGCCAAGTCCATGAGGGATAATCTATCCATAGAAACTGAATTGGCCGATGTGACAATCATCACAAGTGACGGCCATAAGATACCGGCTCATAAGTTCGTATTATCAGcACGCAGCAAAGTCTTTGCGGCCATGTTCAAGCATCCATTTAAGGAAAATAGAGATAATTGTGTTGATATTAGCGAATTTAGTTTCGCTGTTGTCACGGAACTGCTACAATTCATGTACACGGGGGAAGCACCTAAATTGGGAGATATGCCAGTAGATCTACTGGCGGCAGCTGACAAGTACCAGCTCGATAGACTTAAGGCGCTGTGTGCCAAGTCCATGAGGGATAATCTATCCATAGAAACTGCACCTATGGTCCTAGACGCAGCCGATCTCTACAACATGAAAGATCTTAAGATCGagacaattcaatttattcaaaCCAATGCTGGCGAAATAACAAAGACGTCAAACTGgagaaatattattacaacACACAGAAAGTTGATTTTAGAGGCTTTGGTCGAACAAAAACTACAAGaattaaacataaatgaaGATTATTTGGATGAgccaagaaaatataaataa
- Protein Sequence
- MLNTKELADVTIVTSDGHKIPAHKFVLSARSKVFAAMFKHPFKENRDNCVDISEFSFAVVTELLQFMYTGEAPKLGDMPVDLLAAADKYQLDRLKALCAKSMRDNLSIETELADVTIITSDGHKIPAHKFVLSARSKVFAAMFKHPFKENGDNCVDISEFSFAVVTELLQFMYTGEAPKLGDMPVDLLAAADKYQLDRLKALCAKSMRDNLSIETELADVTIITSDGHKIPAHKFVLSARSKVFAAMFKHPFKENRDNCVDISEFSFAVVTELLQFMYTGEAPKLGDMPVDLLAAADKYQLDRLKALCAKSMRDNLSIETAPMVLDAADLYNMKDLKIETIQFIQTNAGEITKTSNWRNIITTHRKLILEALVEQKLQELNINEDYLDEPRKYK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -