Dfal017045.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila falleni
Gene Symbol
Dsp1
Assembly
GCA_035045575.1
Location
JAWNOV010000185.1:10512200-10516338[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.1e-16 7.9e-14 52.0 4.5 5 68 193 258 189 259 0.96
2 2 1.7e-24 1.2e-21 77.0 0.8 1 69 281 349 281 349 0.99

Sequence Information

Coding Sequence
ATGGAACACTTTCATCAAATTCAGCAAACAATTCAACACTATCAGCAGCAACTGGCtgcgcagcaacaacaacaagcggctgcagtacaacagcaacagttgcaacaacatcaagtaGTTGTCCAGCAGAATCAACAGCAGGCGCATCAAAATAGCTCCAATACAACAGCCGGCGTTGGCACCCAACAGCTATTTACATACAAAATGGCAAGTAGTTTCCCCAATCCGGCAACGACAATGGCACAAGTTGTTGCCACATCGAATGCGGCCACCACCGGCTACGATTACCGTCTAAATATGGCACAAGCGGCAGCAGCCGCTGCAGTTCCTGGCTCCCAATGGTGGTATTCGGCTGCCAATCAGGGACAGGTGGATGCCAACACAGCTgcacagttgcagcagcagcaacaacagcagcaacagcagcagcaacagcaacaacagcagcaacaacagcagcagcaacaacagcagcaacagcaacaaatgcaacaacagcaacagcaacaaaatgtcaTCAACTCAGCCGGTAGCCCAATGGTCAGAGGAAAAGCTGATGCGAAACCCAGAGGCCGAATGACCGCCTATGCATACTTTGTACAAACATGCAGAGAGGAGCACAAAAAGAAGCATCCCGATGAGACGGTGATATTTGCCGAATTCTCCCGAAAATGTGCCGAGAGATGGAAGaCAATGGTCGATAAGGAGAAGAAACGTTTCCATGAAATGGCTGAAAAAGACAAGCAGAGATACGAGACGGAAATGCAGAACTATGTACCGCCCAAGGGTGCTGTTGTGGGACGTggcaagaaaagaaaacagatCAAGGACCCAAATGCGCCAAAACGTTCATTGTCTGCGTTCTTCTGGTTCTGCAATGATGAAAGAAATAAAGTGAAGGCTCTTAATCCCGAATTCGGTGTTGGTGATATTGCCAAAGAGCTGGGCCGCAAATGGTCCGATGTTGATCCCGAAGTGAAGCAAAAATACGAATCGATGGCCGAGCGGGATAAGGCACGATATGAGAGGGAAATGACCGAGTACAAGACAAGCGGGAAAATTGCCATGTCAGCGCCCTCAATGCAAGCGTCGCTGCAGGCGCAGGCACAAGCGGTGCAGAAAGCAGCGTTATTAGCAGCTGCtgcccaacaacaactggaTGAGCAacatgacgatgatgatggtgaCGGTGATGATGACGAGAATCAATAG
Protein Sequence
MEHFHQIQQTIQHYQQQLAAQQQQQAAAVQQQQLQQHQVVVQQNQQQAHQNSSNTTAGVGTQQLFTYKMASSFPNPATTMAQVVATSNAATTGYDYRLNMAQAAAAAAVPGSQWWYSAANQGQVDANTAAQLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQMQQQQQQQNVINSAGSPMVRGKADAKPRGRMTAYAYFVQTCREEHKKKHPDETVIFAEFSRKCAERWKTMVDKEKKRFHEMAEKDKQRYETEMQNYVPPKGAVVGRGKKRKQIKDPNAPKRSLSAFFWFCNDERNKVKALNPEFGVGDIAKELGRKWSDVDPEVKQKYESMAERDKARYEREMTEYKTSGKIAMSAPSMQASLQAQAQAVQKAALLAAAAQQQLDEQHDDDDGDGDDDENQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00603303;
90% Identity
iTF_00518401; iTF_00511234; iTF_00535270; iTF_00570356; iTF_00607029; iTF_00543703; iTF_00521313; iTF_00566753; iTF_00495074; iTF_00497346; iTF_00564611; iTF_00501764; iTF_00593062; iTF_00528008; iTF_00552264; iTF_00597322; iTF_00513419; iTF_00500269; iTF_00496559; iTF_00576304; iTF_00498833; iTF_00482194; iTF_00522132; iTF_00609845; iTF_00516952; iTF_00499546; iTF_00574011; iTF_00619803; iTF_00485820; iTF_00548764; iTF_00560222; iTF_00616158; iTF_00525087; iTF_00542399; iTF_00558623; iTF_00498112; iTF_00577024; iTF_00595907; iTF_00582919; iTF_00580680; iTF_00517668; iTF_00580679; iTF_00473739; iTF_00574770; iTF_00471571; iTF_00480821; iTF_00514847; iTF_01327849; iTF_00591660; iTF_00619111; iTF_00557168; iTF_01326354; iTF_01327126; iTF_01325623; iTF_01321880; iTF_01320429; iTF_01321151; iTF_00588801; iTF_00537471; iTF_00527267; iTF_00541032; iTF_00594506; iTF_00488624; iTF_00477978; iTF_00480124; iTF_00578499; iTF_00536727; iTF_00581495; iTF_00614147; iTF_00509061; iTF_00520591; iTF_00612772; iTF_00515558; iTF_00550214; iTF_00805926; iTF_00509063; iTF_00509062; iTF_00504648; iTF_00568936; iTF_00470827; iTF_00595208; iTF_00589508; iTF_00501005; iTF_00483650; iTF_01318991; iTF_00491472; iTF_00479441; iTF_00540327; iTF_00554343; iTF_00516218; iTF_00473021; iTF_00602545; iTF_00604802; iTF_00505362; iTF_00477299; iTF_00545925; iTF_00548026; iTF_00614867; iTF_00563862; iTF_00603303; iTF_00551546; iTF_00606266; iTF_00804348; iTF_01356094; iTF_00481503; iTF_00592351; iTF_00539619; iTF_00596607; iTF_00553696; iTF_00562432; iTF_00472325;
80% Identity
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