Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:1980010-1984982[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00014 0.0091 16.1 1.2 1 23 161 184 161 184 0.96

2 14 0.021 1.3 9.3 3.8 2 23 233 255 229 255 0.89

3 14 0.0064 0.4 10.9 0.8 1 23 349 372 349 372 0.93

4 14 0.05 3.2 8.1 3.1 2 23 421 443 420 444 0.93

5 14 0.00057 0.036 14.2 0.4 1 23 513 536 513 536 0.92

6 14 5.8 3.7e+02 1.6 0.1 2 14 555 567 554 579 0.83

7 14 0.00019 0.012 15.7 1.6 2 23 587 609 587 609 0.96

8 14 0.0051 0.32 11.2 0.1 1 20 701 720 701 722 0.95

9 14 0.00094 0.06 13.5 0.2 1 23 755 778 755 778 0.93

10 14 0.002 0.13 12.5 1.5 2 23 828 850 827 850 0.95

11 14 0.016 0.99 9.7 1.8 1 23 942 965 942 965 0.91

12 14 0.025 1.6 9.0 1.2 1 21 1017 1037 1017 1038 0.95

13 14 0.71 45 4.5 0.2 3 23 1070 1093 1068 1093 0.85

14 14 3.1 2e+02 2.4 0.1 1 10 1111 1120 1111 1127 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00014	0.0091	16.1	1.2	1	23	161	184	161	184	0.96
2	14	0.021	1.3	9.3	3.8	2	23	233	255	229	255	0.89
3	14	0.0064	0.4	10.9	0.8	1	23	349	372	349	372	0.93
4	14	0.05	3.2	8.1	3.1	2	23	421	443	420	444	0.93
5	14	0.00057	0.036	14.2	0.4	1	23	513	536	513	536	0.92
6	14	5.8	3.7e+02	1.6	0.1	2	14	555	567	554	579	0.83
7	14	0.00019	0.012	15.7	1.6	2	23	587	609	587	609	0.96
8	14	0.0051	0.32	11.2	0.1	1	20	701	720	701	722	0.95
9	14	0.00094	0.06	13.5	0.2	1	23	755	778	755	778	0.93
10	14	0.002	0.13	12.5	1.5	2	23	828	850	827	850	0.95
11	14	0.016	0.99	9.7	1.8	1	23	942	965	942	965	0.91
12	14	0.025	1.6	9.0	1.2	1	21	1017	1037	1017	1038	0.95
13	14	0.71	45	4.5	0.2	3	23	1070	1093	1068	1093	0.85
14	14	3.1	2e+02	2.4	0.1	1	10	1111	1120	1111	1127	0.79

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTATGGACGTCGATGTTCTCATCCGATTTTGAGGAGGGTGAGCCGGAAGCGGAACCGGAGGGCAGCGAGCAATACGGAAATGGCAATGATGATTTCATAGGAGATTCGGAGATCCTGGAAGCAGGAGACGCCATTGATGATCTGCTCGAAGGCGAAGACGATGAAAGGGAAGAAGAGGAGTACGAGGATAGCCCAAAGGCAACAAAGAAACCTGATCCCGACGACGATGCTCTTTTTGACTTTGATACGGAGCCTATTGTAAGCATTGCCGAGCCAAATAACTCGGTTTTGGCCCCTGCGGGACCCATGGGCCATCGTGTTCGGCCCCCGACGCAGCGTCAATCAGTGCCCGGTGCTTTGGGTCGACCCAGAATAGGTCCTGGTCTCTCCGTAAGACCCACCACCTCGCAGATCAATGCTACGGATGAGAATGGGGTGCCTATTAACTACGAGCTGGGCGTGGTCTACATCTGCCCTGCCTGCGGCGGAGAGTTCCGCCAACAGGACCACTGGAAGCGGCATATGAACCACATCCACAAGTACAACACCCTGCGTGGCTTGAATTTCACGCCGCTAGATAAACTTTATCAGCGCTGCAAGGAGTGTAACAAGCGAATCGCTATGCATAGCCGGGAGAATCTTCTCAAGCACAAGTTCACTCACCTGCCCTTCAGGTGTACCAAATGCTACTTCTGCAAGCGGGAGTACAAATACAGGCAAGATCTTATGGTTCACCTGCGCTTGGTACACTGTGACGAAGTGGTGGCCATGATGCGGGGGGGATATAATGCTGCAGGCCGTAAGACGCGGGTTAGGGAATCTAGAACCGAGCAATTGCAGCGGGAAAAGAGCTTCCGAGAGAATAATGACTttgaggaggaggaagatCGCATAGAGGTGCGGAATGAGTTGCTCGAGCCAGATGCGGATGAGGTCGGTCTCCTGGAGCAACCTTTGGTGGAGGAAGTTTCCAAGAAGAAGGTTTCACGAAATCGAGGGGCTGCCGAACTGTGCGAGGATTACATACACTACATGTGCCCCGACTGTGGAACCGAATGCGACACACATGCACAATGGAGTCAGCACATCGAGTTCGTTCATGACTACGTGAGCCGAAGGGGACTTAATTTCCGGAGCGTAGATATGCAGATGCAATGCCTAGAGTGCAAAAAGATTGTGATTCCAAACACCATAAAATCGCTGCGCTCCCACAAATTCAGCCATTTGTCGCAGCCAGAGTGGCTGCGCTGCAAACTCTGCTACAGGGGTTTCACGGATCATCAGGAGGTGATCAGACATCTGCTGCAGCAGCACCACATGGATTCGCTGATGTCGGAGGAAATTGAGGACGAGGATGGTGATGGTTCGTTATCCATAATGCAGCAAGAAGAATCCGTCGAGGATAACGGAAACGGCGAAGGTAGTGGCGCCCCCTTGGACGAAGACTCTCCTTACTTTGAAGACGCGCCCAGACGCGGCGGGCGCATCAGCAGCGATGACATGTTTGAGCCTCACATCGACTATCTCTGCCCGCAGTGCGGTAAAGAGTTCATCGAGAAGAAGCATTGGCGCACCCATGTGGTCATGGCGCACAGCATGAACGATCTGACGAAGCTGAACTTTGAGATGATCAACGAACGGCAACTGAAATGTACTGAGTGCGAGAAGATAATCACCAACGCGTATGGAATCCAGAATGCCCAGCAGCACAGGATCACCCATCTTCCGTTCAAGGCGTACGCCAGATGTCGCAAGTGCAACAAGTCGTACACGGATAGGAAAGGTCTCGTCAAGCATCTGGCTACTTATCATGGCGTTGGTTGGCCAAAAAGGTCCGCCGGAGAAGTTGGTGTGCCAGCTTCGTTGCCCACACCCATCAAGCAACCCCGCAAGCAGATCGTGACGGTGGCGAATGAAACATACGAGATAATTTATCTTGACGACGTCGATCAAGGCGAAATGGAAGAGGATAACGATTTTGGAGAACAGATGCAGGCGGATGAAGAGGATTACCTGATTgcaccagctccagctcctcctccacctcctcctcctccgccaccCTCGCAAGGACCTCATCAACGCTATAAGTGCGTCCATTGCGGTACACTCTTTCCCACCCAGGCGGCTGTACGGGTTCACATAAGCGAGAAACGTTGCAGGAAGACAGTCGGCAGAAGAAGTCGACAGGCCGTGAATTCAGCCGGGTTGGACCCATCCGTTCCCACCGTGGAACAAAACTACATCTTCTTGTGTCCTTCCTGTGGCATGGAATATAAGACTCAGTTCGAGTGGCGTCGTCACATTAATGAGGTACACAACTTTGACAAGCGGCAATATCTTAATATGAAGCAGTTGGATAAGTACCGTTACCAATGCACTCAGTGCAAGGACATTGTGTGCAATTCGAAGCTGAAGGGGTTGCAAGACCACCACTTCCGACACCTGCCATACCGACTGTATCTTAAGTGCCTAATATGTGGTACTTGCTACAATCATAAGCCGAACATTGCGGCACATTTGAGAGCCCGACACAGCATCTACGATAGAGAGGCACCGGCGATGATCACCAAACCGAAGCAGGTGTTCGGCCGCCACAAGGATAACAGCAGTAAGGAGAAACCAAGACTGTCCTCTCCGCCTCCAGCACCACCGTCTCCCCCGGCATGCTCCTCATCATCTGCTTCCTCAGTGGCCAGTCGTTCATTAAAACCACAGCCTGGGGGTTTACCCACTCGACCCGCTGGTCTCAACACATTGGAGGACAGCATCTCATACCATAATGCCGTGGATTTAGACTTCATCACGTATTTCTGCCCCAAGTGTAATCAAAACTTTGACTCACATGCATTCTGGCGAAAACACATCGTGGAGCAACACAACTTTAATAGTCGGGAAGGACTGAACTTCCGCCAAATCGATAACCATCACTACCTGTGCCTGGAGTGCTACAAGCGGGTGACCGTGACCCACACCAAAGGCGCAATCGGGCAACTGCAGTCACACAAGTTCCGCCACCTGCCGCATCGATCGTTTAAGTGCTTGACATGTGACGGCGAATTTGTACGCAAGCAAATGTTCTTCAAGCACCTGAATCGCGACACCAATCGCTGTGATAATCGCCCGCACAGAGATTTGGAAGACGATGACGCGGAACAGGAGACGCAGCTGCAATCCATTTTTCACCTGGCGTGTCCGCAGTGCGGTGACAACTTTACAACACGCAACAAGACACAGTGGCGCGAGCATATTAACGACTACCATGGTTTGGCGAAGTTGGACCTATTGCACATGAGCAAAGTGGATGACAACCTTTACCGCTGCCAGGACTGTGACGAGGAGCTACAGACAAATCGACAGTGGGTATTGCAGTTCCATCGATTCCAGCACCTGCCACATGCAGCCTACATCCGTTGTAAACTGTGCAAGCAGAGCAATGAAGCTGGTGCAGCATCGGCGGGGGAGTTACATAGCCTACGTGAACTGCAACAGCACCTACGTAAGCACCATCCAACGGTAGGCGAAAACGAAATGATATTACTCCGAGAGCAGATTGTTCTGGAGGAGAAGGAACAAGAAGAAGGGGGGGAACTGCCCGCAGACGAGGAAAGCCAAGCTGACCAAGATTCTGGACCGTATATGCCGCTACCGCCGCATTTATTGGACGATGGGGACGACATAGAATTCGAGGACCAGTATCTGCTGGGCTAG
Protein Sequence: MEGMDLWTSMFSSDFEEGEPEAEPEGSEQYGNGNDDFIGDSEILEAGDAIDDLLEGEDDEREEEEYEDSPKATKKPDPDDDALFDFDTEPIVSIAEPNNSVLAPAGPMGHRVRPPTQRQSVPGALGRPRIGPGLSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCKECNKRIAMHSRENLLKHKFTHLPFRCTKCYFCKREYKYRQDLMVHLRLVHCDEVVAMMRGGYNAAGRKTRVRESRTEQLQREKSFRENNDFEEEEDRIEVRNELLEPDADEVGLLEQPLVEEVSKKKVSRNRGAAELCEDYIHYMCPDCGTECDTHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVIPNTIKSLRSHKFSHLSQPEWLRCKLCYRGFTDHQEVIRHLLQQHHMDSLMSEEIEDEDGDGSLSIMQQEESVEDNGNGEGSGAPLDEDSPYFEDAPRRGGRISSDDMFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLTKLNFEMINERQLKCTECEKIITNAYGIQNAQQHRITHLPFKAYARCRKCNKSYTDRKGLVKHLATYHGVGWPKRSAGEVGVPASLPTPIKQPRKQIVTVANETYEIIYLDDVDQGEMEEDNDFGEQMQADEEDYLIAPAPAPPPPPPPPPPSQGPHQRYKCVHCGTLFPTQAAVRVHISEKRCRKTVGRRSRQAVNSAGLDPSVPTVEQNYIFLCPSCGMEYKTQFEWRRHINEVHNFDKRQYLNMKQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIYDREAPAMITKPKQVFGRHKDNSSKEKPRLSSPPPAPPSPPACSSSSASSVASRSLKPQPGGLPTRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPHRDLEDDDAEQETQLQSIFHLACPQCGDNFTTRNKTQWREHINDYHGLAKLDLLHMSKVDDNLYRCQDCDEELQTNRQWVLQFHRFQHLPHAAYIRCKLCKQSNEAGAASAGELHSLRELQQHLRKHHPTVGENEMILLREQIVLEEKEQEEGGELPADEESQADQDSGPYMPLPPHLLDDGDDIEFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00486896;
90% Identity: -
80% Identity: -