Deug009241.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila eugracilis
Gene Symbol
RREB1
Assembly
GCA_018153835.1
Location
NW:1317244-1327502[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.03 1.9 8.8 0.8 1 21 254 274 254 276 0.93
2 13 0.00028 0.018 15.2 0.2 1 23 286 308 286 308 0.98
3 13 6.7e-05 0.0042 17.1 7.3 1 23 314 336 314 336 0.98
4 13 3.2 2e+02 2.4 4.6 2 19 549 566 549 568 0.97
5 13 0.0073 0.46 10.7 0.1 1 23 710 732 710 732 0.97
6 13 1e-05 0.00065 19.7 0.7 1 23 742 764 742 764 0.99
7 13 0.00068 0.043 13.9 2.0 1 23 770 793 770 793 0.97
8 13 0.0024 0.16 12.2 2.0 1 23 1061 1084 1061 1084 0.95
9 13 7.1e-05 0.0045 17.0 0.3 2 23 1454 1475 1453 1475 0.97
10 13 0.12 7.6 6.9 6.3 1 23 1481 1504 1481 1504 0.97
11 13 6.4 4e+02 1.4 2.0 1 23 1626 1649 1626 1649 0.83
12 13 0.007 0.44 10.8 0.5 3 23 1705 1725 1703 1725 0.96
13 13 0.0012 0.073 13.2 4.8 1 23 1731 1753 1731 1753 0.99

Sequence Information

Coding Sequence
ATGCTTGCCGCACATCAGCAGCACAACAACAGCACAGTGGAAACCGAAATGGAGCGTCAGCGACGTGACTCTACAACATCAGAGTCCTCACTGGAGCATCTGGACTTGGGTCGTACGCCCAAGAAATTGGGTGGTAATGGTGTTACAACACAAACAACATCAACGCCACGTGACTTGACGGCAGTGACGTCGCGCAAGCGCAAACTTcgacaactgcaacaacatcagcagcagcagcagcagcaacagcagcagcagcagcagcaacaggatTTGCTAActgatgaggatgaggaggaggaggcgatGGATGAGGATGATATAGATGAACAGCAGGTGGCTTCCAGAAATATGGGACGCCACAAGCAGCGACGCAGTGGCGCCACTACACAGGCCTCCATTGTCGTTGATTATAGCAGCGGTGATGCCAGTTCGTTGCGCAAAAAGTTCCGTCTCAATCGCTCGGCTCCGAGTCTCTCGGAATCGGGATTTGTGGATGCCAGTAGTACAACCGGTCATAGTGGTTATCTGGGTAATAGTAGTACTGGCAGTACTACCAATACAACTATACCAGCCAGTGGTACCATCGTTCCATCATCGTTGGGTGGCGATAATGGTGTTGTTGTGACAGCAGGAGCCTCAaatagcagtagcagtagTGGTAGCAGTAGCAGTGGTGGATCCGGTGGTTCATCACCGCAGGGATTGTGCTTGTCAAGCGGTGAATCTGGCATCGGTGCCGGGGATGAGCATATGAAATACCTTTGCCCCATCTGTGAAGTGGTATCGGCCACGCCCCATGAGTTCACCAACCATATCCGGTGCCACAATTACGCCAACGGCGATACGGAGAACTTCACCTGCCGCATTTGCTCTAAGgtGCTATCCTCGGCTTCATCCCTGGACAGACACGTGCTGGTTCACACGGGCGAGCGGCCCTTTAACTGCCGCTACTGCCACCTGACCTTCACCACCAATGGCAACATGCACCGTCATATGCGCACCCACAAGCAGCATCAAGTTGCGCAgtcgcaacagcagcagcagcagcaacagcaacagtcacagcagcagcagcagcagcagcgacgacagcagcAAAATCAGCAgtcacagcagcaacagaatcccgcccagcagcaacagcaattggTGGCCAGCACATTATCCGGACGAGCAGAGAGTTATGAGAGTGATGGCAGCTGCTCAACGGATGTGTCCAGTGGTCATAGTCATAGTCGCAGCAGTAGCTCCCTTaatcacaacaacaataactcGCACAAGGCTAACCATAATCTTAAGGAGGAGCTAGATGATCACGTTGAAGATCAGCAGGAGTTGGAGAATAAGCAGCGTCGCCTGAAGACCACCATCAATAACAACATCATTGATAGTGAGCATCAAGGGGATATCGATGATGAGGAGGCTGATGATACAGATGTGGCCATGCTAACTAGTACACCCGATGTGGCCACCCTATTGGCCGGAGCCAGTGCATCTGGTGCTGCATCGCGTTCACCAACACCATCGCCATCTGCCTCGCCTGCTTTGGTCCTCAATTGCCCGGCCTGTGGTGCCTCCGATTTTGAGACTTTACCCGCTTTATGTGCCCATTTGGATGCCAGTCATTCGGATATACCCGCCAAGTGTCGGGATTGTGAGGTCATCTTTGCCACTCATCGTCAGCTGCAGTCGCATTGCTGTCGCGGATCGTCCATCATGGGTGTCGGTTTGCCACCTCTACTCGGTGCCAGCAGTTCACCATTGCACAATGAAGACGCCGAAGATGAAGAGCACGATCATGATGAGAATCTCGAGCAGAAGGGAAGAATACCAACTCAAAGCGAGGACTTCTTCCATCAATTGTATTTGAAGCAAAAGACATCCAGTGGTGCCATCTCGCATCCTCCGTCTCCTATTAAACACGAGCCGGCGGATAGCAAGGATCTGGCCGATATCCAGAGCATTCTGAACATgaccagttccagttccagtttccTGCGTAACTTTGAACAATCCGTAAATACACCCAGTTCGAGTCAGTACAGTTTGGATGGTCGAGATCAGGAGGAGGAAGCCCAAGATGCATTCACCTCGGAATTCCGCAGGATGAAGCTGCGCGGCGAGTTCCCTTGCAAGCTGTGCTCTGCCGTTTTTCCCAATCTTCGTGCCTTGAAGGGTCACAATAGAGTTCATTTGGGTTCCGTAGGTCCAGCTGGACCCTTCCGTTGCAACATGTGTCCCTATGCCGTTTGCGATAAGGCCGCCCTGGTGCGGCACATGCGCACCCACAATGGTGACCGTCCATATGAATGCGCCGTTTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAACGTCATCTGAGGAATCGTCATGGAAAGACCAGTCGCGAGGAAGTCAAGCGGGCCATAGTCTATCATCCGGCGGAAGATGCTGGCTGTGAGGATAGCAAATCACGTTTGGGTGAGGATCTAGCCGATATGAGTTTCCGTTCGATTAGTCCaacgccaccgccaccgccggTCAACGAGAGCAGCTCACAGCTGAAGCACATGCTTTTGGGTGAGAATCATATGGCTCCCGTTGCCCAGCCACCATTGAAGATTCAGGTGAAGAGTCTCGATCAGTTGGTGGACAAGAAGCCATCTGTACCAGCgcctcagcagcagcagcagcagcagcagcagcaggagaaggGCGGAGCTGCTTTGGACTTTAGCATGGATGTCTTGGATCTCAGCAAGAAGCCAACTGGTGGAGCTTTACTAACACCATCAGTTACTCCAACTCCAACGCCGGCTACCGTGGCTCCGATTGTTCCAGGAATTGTTACCCCTGACTTGGCCGCCGCCATGGAGGAGCAGCAATTGCTATTGGCTCAGCGACAACTGTTCGGCGGTGCCGGAGATGCTGCCTCTCAGTATGTGCAACAATTATTCCGCAGCCTGATGTTCCAATCGCAAACGCCGGGATTTTCGTTCTTTCCATTTATggcaccaccaccgccacaaTCGAATCCCGAGAAGCCACCACTGGTGAGTCCACCAAATCGCTTGAATGCTTTGCCCGTTGGTGTCGGTGTGCCAGTGCCTCCCGGCGGTCCCGTCAAGATGGTCATCAAGAATGGTGTCCTAATGCCCAAGCAGAAGCAACGTCGCTATCGCACCGAACGTCCATTTGCCTGTGAGCATTGCTCGGCAAGATTCACGCTGCGTTCGAATATGGAGCGACATGTAAAGCAACAGCATCCCCAGTTCTATGCTCAACGTCAGAGAAGTGGCCACCATGTGATGAGGGGCAGAGGAGCATCCaatgccgccgctgctgctgccgccgctgcagctgcagctgccatGGGTCAAGTTCCAGTTGGTGGATCAGGATCCTTGGCCACAGGCTCTAATCATCATCATGGCCATAGCCATAGTTCCCATGGACATGCTCCAATTTCGGAGCAGGTGAAATATGCCATCCTGGCACAGCAATTGAAAGCTCACAAGAACACCGATCTCCTACAGCAGGCTTTGGCTCATGGTTCTAGCAGTGTTGCTGGTAATCCTCTCCTTCAATTCGGCTATCCACTTGCCACACCCAGTCCCCTGCACAATGGCAGCCAGGGTAATGGTCAGGCCATGACCATGGATGATGATGAACCCAAGCTGGTCATTGATGAGGATGAAAACGAGCATGATCGTGAGATGGAAGCTGAGGAAGGTGATGATTTCgaagaagatgaagatgaggaGGAGCTGGATGAGCCGGAAGATGAGCCCGAGTTGATTGCCGATGAGCAGCCAGTCGAAGAGGAAGCAGAGGAAGAACAAGATCTGCCCAAACCTCTGGAGCAATTGGCCTTCGTTGCGGCATCCAATGAAGCGGCTCAGAAAATGGCCGAAACTATCTTGGAGCAGGCCATTAAAGCGGGCAAGCCGTCGAGTCCATCGCCCCAGGAGAATGCCACGCCAGTTAATCCAAGTGTAGCTACTACCATGCAGGAACCAGCCACCACCTCTCCACCCAGTAATCCAAGCAGTTTGAAAGCCATGATTGCCCAAGCCGAATCCGTGGGTAAATCCCTTAAAGAAGTTGCCAGTTCTCCGTTTAAAGATGAATCCCAAGATCTGGTGCCAGTGGCCAAATTGGTGGACAATGCCACCAGCCAGAACATGAGCTTCAATAGCTATTTCCGACCCAGCGATGTGGCCAATCACATGGAACAGAGCGACGAAGAGGGTCTGGTGGCCTCCGGTAGTGCCAGCGAGAGTAACAATAGTGGCACCGAGGACGTTACCAGCAGCAGTTCCGGCAGTGAGCCCAAAAAGAAGTCCGCTTATAGCTTGGCACCCAATCGTGTCTCCTGTCCATACTGCCAGAGAATGTTCCCATGGAGCAGCTCGCTTCGCCGGCACATCCTCACCCATACTGGCCAGAAACCCTTCAAGTGCTCTCATTGCCCATTGCTGTTCACCACCAAAAGCAACTGCGATCGTCATCTGTTGCGCAAACATGGCAATGTGGAGTCCGCTATGTCGGTTTATGTGCCCACCGAGGATGTTAGTGAACCGATACCGGTACCCAAGTCCGTGGAGGAGATCGAATTGGAGGAGCAACGTCGTCGGCAGGAGGCAGAACGTGAAAAGGAACGAGAGCTGGAACGTGAAAGGGAGTTGGAACGCGAAAGGGAACTGGAGCGGGAGCGTGAGttggagaaggagaaggagcgGGAACGTCAACAGCTCATCCAAAAGTTGGCGGCCCAAATGAATGCCGCTGCCAATGCCgccgcagctgctgcagctaGGGCGGGAAATGGTAATGTCACCGGGTCAAATGGACCTATCGTAGATGCTTTGGCTGGCGGAGATTTACCCTATAAGTGCCATCTATGCGAGGGTTCCTTTGCCGAGCGTTTGCAATGCTTGGAGCATATCAAGCAGGCGCATGCCCATGAGTTTGACTTACTCCTGGCCAAGGGAGCCATTGAGAACGAGTCTCTCGAAGCTAATCCTCAACAGCAGCCATCACAGCAATCAGTGCATTCCGATGATGAGGCACCAAATGGTGGAAGCAGGGGCAAATATCCAGACTATAGCAATCGCAAGGTGATCTGTGCCTTTTGCGTACGTCGTTTTTGGTCCACCGAGGATCTGCGTCGTCATATGCGAACCCATTCGGGTGAAAGGCCATTCCAGTGTGATATTTGCCTAAGAAAGTTCACCCTGAAGCACAGCATGCTGAGGCACATGAAAAAGCACAGTGGACGGGCTCATAATGGTGATAATCCAGGATCCGATTGCTCTGACGATGAGCAGGTGAGCAGCCCGCCCAGCACACCACTACCTAGCCAACCACCGACCAGcgccaataacaacaatagctgtcacaacaacaacaataccaataacaataataataataacaacaataacagtgGCTCCAAGTTGGGATTGAAGCTGCCCAAGCTTCATGAGCTACTGGATAAGGCAAGTGAATGGCGTGCCAGCCGACTGGGTGAGCACAAGGAGAACATGGGCGAGGCCACACCATCGGGAGCAGCTGTAGCTGGATCAGATTTGATTGGCAATCTGTTAGGTATCAGTGATCAGGGAATTCTCAATAAGCTTCTGTCCTCCGCCGATGAGGCGGCCAAACTTCTTGGTGTGGACAACAAGTAA
Protein Sequence
MLAAHQQHNNSTVETEMERQRRDSTTSESSLEHLDLGRTPKKLGGNGVTTQTTSTPRDLTAVTSRKRKLRQLQQHQQQQQQQQQQQQQQQDLLTDEDEEEEAMDEDDIDEQQVASRNMGRHKQRRSGATTQASIVVDYSSGDASSLRKKFRLNRSAPSLSESGFVDASSTTGHSGYLGNSSTGSTTNTTIPASGTIVPSSLGGDNGVVVTAGASNSSSSSGSSSSGGSGGSSPQGLCLSSGESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQVAQSQQQQQQQQQQSQQQQQQQRRQQQNQQSQQQQNPAQQQQQLVASTLSGRAESYESDGSCSTDVSSGHSHSRSSSSLNHNNNNSHKANHNLKEELDDHVEDQQELENKQRRLKTTINNNIIDSEHQGDIDDEEADDTDVAMLTSTPDVATLLAGASASGAASRSPTPSPSASPALVLNCPACGASDFETLPALCAHLDASHSDIPAKCRDCEVIFATHRQLQSHCCRGSSIMGVGLPPLLGASSSPLHNEDAEDEEHDHDENLEQKGRIPTQSEDFFHQLYLKQKTSSGAISHPPSPIKHEPADSKDLADIQSILNMTSSSSSFLRNFEQSVNTPSSSQYSLDGRDQEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGSVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDAGCEDSKSRLGEDLADMSFRSISPTPPPPPVNESSSQLKHMLLGENHMAPVAQPPLKIQVKSLDQLVDKKPSVPAPQQQQQQQQQQEKGGAALDFSMDVLDLSKKPTGGALLTPSVTPTPTPATVAPIVPGIVTPDLAAAMEEQQLLLAQRQLFGGAGDAASQYVQQLFRSLMFQSQTPGFSFFPFMAPPPPQSNPEKPPLVSPPNRLNALPVGVGVPVPPGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASNAAAAAAAAAAAAAMGQVPVGGSGSLATGSNHHHGHSHSSHGHAPISEQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAGNPLLQFGYPLATPSPLHNGSQGNGQAMTMDDDEPKLVIDEDENEHDREMEAEEGDDFEEDEDEEELDEPEDEPELIADEQPVEEEAEEEQDLPKPLEQLAFVAASNEAAQKMAETILEQAIKAGKPSSPSPQENATPVNPSVATTMQEPATTSPPSNPSSLKAMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSQNMSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSGSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQEAEREKERELERERELERERELERERELEKEKERERQQLIQKLAAQMNAAANAAAAAAARAGNGNVTGSNGPIVDALAGGDLPYKCHLCEGSFAERLQCLEHIKQAHAHEFDLLLAKGAIENESLEANPQQQPSQQSVHSDDEAPNGGSRGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGRAHNGDNPGSDCSDDEQVSSPPSTPLPSQPPTSANNNNSCHNNNNTNNNNNNNNNNSGSKLGLKLPKLHELLDKASEWRASRLGEHKENMGEATPSGAAVAGSDLIGNLLGISDQGILNKLLSSADEAAKLLGVDNK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00605068;
90% Identity
-
80% Identity
-