Basic Information

Insect: Drosophila eugracilis
Gene Symbol: -
Assembly: GCA_018153835.1
Location: NW:3693316-3698050[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0019 0.12 12.5 0.9 1 23 209 231 209 231 0.96

2 26 1.5 94 3.4 3.2 1 20 237 256 237 259 0.81

3 26 0.00073 0.047 13.8 0.7 2 23 291 312 290 312 0.97

4 26 0.0032 0.2 11.8 2.9 1 23 385 408 385 408 0.92

5 26 0.21 13 6.1 1.2 1 23 448 470 448 470 0.97

6 26 0.23 15 6.0 0.1 3 23 479 499 478 499 0.97

7 26 0.0024 0.15 12.2 0.2 1 23 574 597 574 597 0.97

8 26 0.0013 0.084 13.0 0.3 2 21 607 626 606 627 0.93

9 26 0.00083 0.053 13.7 3.9 1 23 636 658 636 659 0.96

10 26 0.0023 0.15 12.3 1.4 2 23 673 694 672 694 0.97

11 26 0.00022 0.014 15.5 7.1 1 23 702 724 702 724 0.97

12 26 0.69 44 4.5 2.6 2 23 759 780 758 780 0.83

13 26 0.013 0.85 9.9 0.3 1 23 862 885 862 885 0.94

14 26 0.76 48 4.4 0.7 2 20 893 911 892 913 0.71

15 26 0.0038 0.24 11.6 1.0 1 23 922 945 922 945 0.96

16 26 3.9e-05 0.0025 17.9 2.4 2 23 964 985 963 985 0.97

17 26 0.00039 0.025 14.7 1.0 1 23 992 1014 992 1014 0.98

18 26 1.9 1.2e+02 3.1 0.1 2 21 1041 1060 1040 1061 0.92

19 26 0.01 0.66 10.2 3.2 1 23 1111 1134 1111 1134 0.96

20 26 0.0038 0.24 11.6 5.0 1 23 1171 1193 1171 1194 0.96

21 26 0.00054 0.034 14.3 2.7 1 23 1220 1243 1220 1243 0.98

22 26 4.7e-06 0.0003 20.7 0.2 2 23 1269 1290 1268 1290 0.95

23 26 0.00021 0.014 15.5 3.6 1 23 1296 1318 1296 1318 0.99

24 26 1.8e-06 0.00012 22.0 2.0 1 23 1324 1346 1324 1346 0.97

25 26 1.6e-07 1e-05 25.3 2.4 1 23 1352 1374 1352 1374 0.99

26 26 0.00083 0.053 13.7 0.2 1 22 1380 1401 1380 1404 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0019	0.12	12.5	0.9	1	23	209	231	209	231	0.96
2	26	1.5	94	3.4	3.2	1	20	237	256	237	259	0.81
3	26	0.00073	0.047	13.8	0.7	2	23	291	312	290	312	0.97
4	26	0.0032	0.2	11.8	2.9	1	23	385	408	385	408	0.92
5	26	0.21	13	6.1	1.2	1	23	448	470	448	470	0.97
6	26	0.23	15	6.0	0.1	3	23	479	499	478	499	0.97
7	26	0.0024	0.15	12.2	0.2	1	23	574	597	574	597	0.97
8	26	0.0013	0.084	13.0	0.3	2	21	607	626	606	627	0.93
9	26	0.00083	0.053	13.7	3.9	1	23	636	658	636	659	0.96
10	26	0.0023	0.15	12.3	1.4	2	23	673	694	672	694	0.97
11	26	0.00022	0.014	15.5	7.1	1	23	702	724	702	724	0.97
12	26	0.69	44	4.5	2.6	2	23	759	780	758	780	0.83
13	26	0.013	0.85	9.9	0.3	1	23	862	885	862	885	0.94
14	26	0.76	48	4.4	0.7	2	20	893	911	892	913	0.71
15	26	0.0038	0.24	11.6	1.0	1	23	922	945	922	945	0.96
16	26	3.9e-05	0.0025	17.9	2.4	2	23	964	985	963	985	0.97
17	26	0.00039	0.025	14.7	1.0	1	23	992	1014	992	1014	0.98
18	26	1.9	1.2e+02	3.1	0.1	2	21	1041	1060	1040	1061	0.92
19	26	0.01	0.66	10.2	3.2	1	23	1111	1134	1111	1134	0.96
20	26	0.0038	0.24	11.6	5.0	1	23	1171	1193	1171	1194	0.96
21	26	0.00054	0.034	14.3	2.7	1	23	1220	1243	1220	1243	0.98
22	26	4.7e-06	0.0003	20.7	0.2	2	23	1269	1290	1268	1290	0.95
23	26	0.00021	0.014	15.5	3.6	1	23	1296	1318	1296	1318	0.99
24	26	1.8e-06	0.00012	22.0	2.0	1	23	1324	1346	1324	1346	0.97
25	26	1.6e-07	1e-05	25.3	2.4	1	23	1352	1374	1352	1374	0.99
26	26	0.00083	0.053	13.7	0.2	1	22	1380	1401	1380	1404	0.91

Sequence Information

Coding Sequence: ATGCTTCCGTCAGACATTTGTCGAACCTGTGCACTGAATAACGTTTGTTTGCTACCCTTATCCACTTGCTTGGAGAGAGACGCTTCCAAAAGTTTCTACGATGTGCTCCAGGAGCTTACGCAAATTGATACCCGGCTAGAGAGCTCGAACGAAAATCTGCCGCAGCATCTGTGCACTGATTGTTGGACAAGGTTAGACAATGCCTATGCCTTTGTGGAGCAGGCCAAACGAGTCAATGGGGAGCTGCTGGCGCGGCTAAGAGAGTGTCTGGATGAAATGCCCATCGACATCCCACCGGAGCAGAACATAAAAACTGAAGTTGACCTCGATGATGAGGCTAATAAGTCCGAGGAGGATGTGGACAGCACTGGAATGGCAAAACTGGAGCTCAAATGGCAGCCAGAAAGTGACAGCGATGAGGAATTCGTTGATGCAGCATTAAGTGATAAAGAAGAGGTGGATAAGAAGCCTTACCATCTGCGACGGAGTTCTCGAAAAGACAAGCAGGCGCCATTAGAAAGCGAGGATGAAGATGTTAAGCCATCTGAATCTTCGCCCATAAAACGGCGTCGAGGACGTCCCCCTGGTCGAGCTAAAAGCCAGTCGATGACCAGCGATGGCCGTCACGCCTGTGAGGTCTGCGATAAGACCTTCTCCTGGTACCGTGACATGCAGCGTCACGCTAGGATTCACTTTGAGAAAGCCTCATACGTGTGTGATACCTGTGGCAAGGGATTCTTGCGTAAGGACAAATACATGTTCCACCTCCGCTGTCACAAAAAACGCGAGGCCAAATGGAAGGCTCTCCAGGTCGGAAAACAATGGCGATTTGCTGAGCGCCTTTATAGCTCCGGAAgattaaagaaaatagaatGTAAGTTGTGTGGATTAAGTTGTCAGCGAATGGAGGAGCTTAGAATTCATATAAATACTCATGTGAACGTGGAGAGTTTGGCCGACTTGAGAAAAGATAGCGATGTGGTCAGAGAGCATTTTGCTGGATTGTCTTGCGACTTAGACACTATCAAGCAAAAGATATGCTCTGACGTAGCCGAAGGACTTTCCGAGAAGTTTGCTTGCATTGTAAATTTTTACGGCTATGAGATGGGTTTGAATGATTCAGATGAAGAGAGTGCTAGCGAGGAGTCGAAGTACAATTGCTTTGTGTGCAATCTATCGTTCACTCGCAAGCACCGCCTGGTAAAACATACTTTGGATGAGCACTCCCAATCTTCTTCAACGCTTCCCTGGCAAAGCTGCGGTTCCTGTAAGGTTGGTTTCCTATGCTTAACACTCTACAATCAACATTTGAACACCCATTGCCACAGTCAAATAAGACGATATCGCTGCCGGAAATGTCCCGGGAAGTTTATGTGGCCAGAAAACCTGCAAAACCATGCATGCTCCCATCGGCGAGCGGAGAAGAAAATATTGTGCACGTTGTGTGATGCTGTGCAAACTAGTTTAGCGCAACTTCGGGTTCACCTAATCACACACCAAAATGATTTGAATGGAATTAGTTTGGATTACAATTCCACCTTCTTTCGATCGTTTTACCCTGATGGACTTGACTGCTCTACATCGGATCTTGCTGCTCGTATATCTGAGGATTTCAATGTCCAGGACTTTGATCGATATTACAATGCCAGTACGGAGAGTGGACGAGAGCTGGATTTGTTCGATTCCGAAACAGATGAAAGCGATGAGGAGACTAGGATATACAGTTGTCTTTTGTGTGGGGAAAATACTAGTACTCTGGCGAGTCTTTTGCAGCACCAAAAGAACATACATTCAGATAGGGCAGCTAATCTGCCCTGTCCCTGCGATGATTGTGGTTCTGGATTCGTCAGCAAAGATCTTCTGGAGCAACACCGTAGGCAAAGATGCGCCAAAACACACTTCCGCTTTCAATGCCATATTTGCAATATTCGATTCGTGTGGCAATCCAATTATGAATTGCATCTGAAGACTCACCATAGCAAAAAACACGATGAAGAAGAACTTACAACAAGGTTGCAATGCGACGAATGTGAAAAGgtcTTCATCTGGCACAAAGATCTCAACCGACACAAGCGACTGCACCAGCCTCAGTCTGCAGCGCCGTTCGACTGCCCTCATTGCCATCGCAGGTTCCATCGCAAGGACGGTCTCAAATCCCACCTTAAAGTGCATGCAGGAGAACCCGATCATATAAAAGAGCTGCCTTTCATACCCAACGTTGTTAATGGAATAACCCTTAGCCGACTTAGTCGTCCCCATGGCTGCAAGCTTATTAGGTGCATGATCTGCCTCTCAACCCACTCAAAAATAAGTAATCTAAGAACTCACATGCGTTCTCATCAATATGAATTAAGTTTTTCCGAAGAGAGAGATATTTCTAGTGCCTCAAAGGCTTTTTACCCGGAACTCGAAAATGTCTTAGGAAGAGATGAACTCGCCGGAAGGATTATGGGTGATGTGCAGCAACAATTGGATTTGGATCGATTTGTGTCTATCACAAACGAGGCTGGTCTAGAGCTGAATCTCGATAGCagtgaaactgaaactgaatcCGAGCAAAAAGAAGATCAATCATTCCAGGGCTACGCTTGCAATCTTTGTGATGTGGTTTCGATGAGAAAGCATCAGTTGTATGCCCACCAGCTAGCGGAGCACAAGTGGGATGAGGCATTCCTTGTATGCTCTCACTGCCAGGCCCGGTTTGTTAACGTATCTTTGCAAGACCATCACTCAAGAACCGTCTGTTACAATCCGCAGAAAGTCTTTCAGTGTCGCAAATGTCCACTTCGGTTCCGCTGGCGGGAGAACCTGCAGCTCCACATAAACCTTTTCCATCAGCAAGTTGAGATTCCAGTCCCAGAAGATTTCCCTCAAGCGGATAGTGATCTGCAGTGCGATAAGTGCCAACGCACCTTTAAGATGCAAAAGGATCTCACGCGTCATACACTGATGCACGGCCAAGAATCGAATATTTTCCGGTGCCGTTGGTGTGCTCGTCGTTTTTATCGCAAGCCCAATCTCCTACAGCATATCGCTCGCCATGGGATAAGTGTTAGCCAATTGCCTTATGCAGAGGCAATTCTAGACTCATATGTGAATCCCGCTGGTCAAAAGAAGATAGAGTGCAAAGTGTGCTGTGTGAGCTTTCCCACCATTGCGGCACTGCGTCTGCATTTGGAAACAATGCCCACAGGCAGTCACCACGACTTGTCATCTCTTCAAAACTACTCGATTACCAACCAAATGGGATACGAGATGGAATTGGATGATTCGGAGACGGATGATAATGACTCTAGGACACATTCAAAACCACCTGGGGCCACGGAGTTTTACACCTGTGGAATGTGCCAACTAAAGTGTTCGCGAAAATTCGAGCTTTATCAACACCAGCAAGCCATGCATCGGATGGAGAAGATCCCCGACGGTTGTGATAGGTGCATCTTTAAAAGTGTCTGCCCGGAAATAATTTCTCATCATAAGAAAACTCAATGTGAAAATCGCGAAAAGCAGTTTAAATGCACCCGCTGTGGCTACAAGTTCATGTGGGAGTCTAACCTATTGCATCACATGCAGATGCATCATGAAAAGCCAGAGGATCAACAGCTTGATGAATCAAAGGAGGCGACAGGTAATGATCCAAAAGCCGATTGTCAGGTCTTTCAGTGTGGACTTTGTACAAGGAAATATAACCGCAAGGATCGGCTCACAGCACACTTGAAGAAGTTTCATGGACCTGATGGCAAAGGCTCAAATGAAGTTAGAACCTCGAATAGACCCACATCTCCTAAGGAACCAAAACGGTTCCTGTGTGCCTTTTGTGGCAAGGCGGTCAGCTCATCCTCCAATCTGATCATACACATGCGCCGGCATACCGGAGAGAAGCCTTTCAAGTGCGATTACTGCACAATGGCCTTCCCGCGTTCCTCTGACCTCCAGTGCCATCGAAGGACGCATACCGGAGAACGTCCTCATGTTTGCACTGTCTGTCAGAAAGGATTCGCCCGCTCGTACAAACTGCAGCAGCACATGAGGATCCATAGCGGAGAACGGCCTTACAAGTGCACCTACTGCGAGAAGAGTTTCACGCAATCCAACGATCTAACACTTCATATCCGTCGGCACACAGGCGAACGGCCCTACCAGTGCGGCGTCTGCGGAGAACGATTTATCCAAGGCACCGCCCTGAAGAATCATCGCATGCAGCAGAGCCACTACGAGGAGGGACAGGAATCAGGAGAGCCCCCAAGACGCACGGTTGTGGAGcagtttaatatataa
Protein Sequence: MLPSDICRTCALNNVCLLPLSTCLERDASKSFYDVLQELTQIDTRLESSNENLPQHLCTDCWTRLDNAYAFVEQAKRVNGELLARLRECLDEMPIDIPPEQNIKTEVDLDDEANKSEEDVDSTGMAKLELKWQPESDSDEEFVDAALSDKEEVDKKPYHLRRSSRKDKQAPLESEDEDVKPSESSPIKRRRGRPPGRAKSQSMTSDGRHACEVCDKTFSWYRDMQRHARIHFEKASYVCDTCGKGFLRKDKYMFHLRCHKKREAKWKALQVGKQWRFAERLYSSGRLKKIECKLCGLSCQRMEELRIHINTHVNVESLADLRKDSDVVREHFAGLSCDLDTIKQKICSDVAEGLSEKFACIVNFYGYEMGLNDSDEESASEESKYNCFVCNLSFTRKHRLVKHTLDEHSQSSSTLPWQSCGSCKVGFLCLTLYNQHLNTHCHSQIRRYRCRKCPGKFMWPENLQNHACSHRRAEKKILCTLCDAVQTSLAQLRVHLITHQNDLNGISLDYNSTFFRSFYPDGLDCSTSDLAARISEDFNVQDFDRYYNASTESGRELDLFDSETDESDEETRIYSCLLCGENTSTLASLLQHQKNIHSDRAANLPCPCDDCGSGFVSKDLLEQHRRQRCAKTHFRFQCHICNIRFVWQSNYELHLKTHHSKKHDEEELTTRLQCDECEKVFIWHKDLNRHKRLHQPQSAAPFDCPHCHRRFHRKDGLKSHLKVHAGEPDHIKELPFIPNVVNGITLSRLSRPHGCKLIRCMICLSTHSKISNLRTHMRSHQYELSFSEERDISSASKAFYPELENVLGRDELAGRIMGDVQQQLDLDRFVSITNEAGLELNLDSSETETESEQKEDQSFQGYACNLCDVVSMRKHQLYAHQLAEHKWDEAFLVCSHCQARFVNVSLQDHHSRTVCYNPQKVFQCRKCPLRFRWRENLQLHINLFHQQVEIPVPEDFPQADSDLQCDKCQRTFKMQKDLTRHTLMHGQESNIFRCRWCARRFYRKPNLLQHIARHGISVSQLPYAEAILDSYVNPAGQKKIECKVCCVSFPTIAALRLHLETMPTGSHHDLSSLQNYSITNQMGYEMELDDSETDDNDSRTHSKPPGATEFYTCGMCQLKCSRKFELYQHQQAMHRMEKIPDGCDRCIFKSVCPEIISHHKKTQCENREKQFKCTRCGYKFMWESNLLHHMQMHHEKPEDQQLDESKEATGNDPKADCQVFQCGLCTRKYNRKDRLTAHLKKFHGPDGKGSNEVRTSNRPTSPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCDYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSHYEEGQESGEPPRRTVVEQFNI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548203;
90% Identity: -
80% Identity: -